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Serum IGF-I levels correlate to improvement of functional outcome after ischemic stroke.

Journal article
Authors Daniel Åberg
Katarina Jood
Christian Blomstrand
Christina Jern
Michael Nilsson
Jörgen Isgaard
N David Åberg
Published in The Journal of clinical endocrinology and metabolism
Volume 96
Issue 7
Pages E1055-64
ISSN 1945-7197
Publication year 2011
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Institute of Medicine, Department of Internal Medicine
Pages E1055-64
Language en
Links dx.doi.org/10.1210/jc.2010-2802
Subject categories Medical and Health Sciences

Abstract

GH has positive cognitive effects when given to GH-IGF-I-deficient patients. GH and IGF-I exert both neuroprotective and regenerative effects on experimental stroke. We investigated whether the endogenous serum IGF-I (s-IGF-I) levels correlated with recovery of functional independence in patients who had suffered an ischemic stroke.

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