To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

A Prospective, Controlled… - University of Gothenburg, Sweden Till startsida
To content Read more about how we use cookies on

A Prospective, Controlled, Multicenter Study to Evaluate the Clinical Outcome of Implant Treatment in Women with Osteoporosis/Osteopenia: 5-Year Results

Journal article
Authors A. Temmerman
Lars Rasmusson
A. Kubler
A. Thor
J. Merheb
M. Quirynen
Published in Journal of Dental Research
Volume 98
Issue 1
Pages 84-90
ISSN 0022-0345
Publication year 2019
Published at Institute of Odontology
Pages 84-90
Language en
Keywords dental implants, marginal bone loss, postmenopausal, long-term outcome, survival rates, bone, bone-mineral density, dental implants, fractures, Dentistry, Oral Surgery & Medicine
Subject categories Dentistry


The impact of osteoporosis on implant treatment is still a matter of debate in the scientific community, as it may possibly lead to higher failure rates. As long-term controlled trials are missing, the aim of this study was to verify the long-term outcome of implants placed in patients with systemic osteoporosis. Postmenopausal women in need of implants underwent bone mineral density measurements in hip and spine, using dual X-ray absorptiometry scans. Based on T-scores, they were divided into 2 groups: group O (osteoporosis group) with a T-score <=-2 or group C (control group) with a T-score of >=-1. Implants were placed in a 2-stage manner and loaded 4 to 8 wk after abutment surgery. Six months after loading and thereafter yearly, clinical and radiographical parameters were assessed. In total, 148 implants were placed in 48 patients (mean age: 67 y [range, 59-83]). Sixty-three implants were placed in 20 patients (group O) and 85 implants in 28 patients (group C). After 5 y, 117 implants (38 in group O and 79 in the group C) in 37 patients were assessed. Cumulative survival rate on an implant level was 96.5% (group O: 91.5%; group C: 100.0% [P < 0.05]) and 95.7% (group O: 89.2%; group C: 100.0% [P > 0.05]) on a patient level. The overall marginal bone-level alterations, after 5 y of loading, were -0.09 +/- 0.78 mm (group O: -0.15 +/- 0.50 mm; group C: -0.06 +/- 0.89 mm) on an implant level and -0.09 +/- 0.54 mm (group O: -0.18 +/- 0.43 mm; group C: 0.06 +/- 0.58 mm) on a patient level (P > 0.05). Oral implant therapy in osteoporotic patients is a reliable treatment option with comparable osseointegration rates, implant survival, and marginal bone-level alterations after 5 y of functional loading ( NCT00745121).

Page Manager: Webmaster|Last update: 9/11/2012

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?