To the top

Page Manager: Webmaster
Last update: 9/11/2012 3:13 PM

Tell a friend about this page
Print version

Clinical and MRI Features… - University of Gothenburg, Sweden Till startsida
Sitemap
To content Read more about how we use cookies on gu.se

Clinical and MRI Features of Cerebral Small-Vessel Disease in Type 1 Diabetes

Journal article
Authors L. M. Thorn
S. Shams
D. Gordin
R. Liebkind
C. Forsblom
P. Summanen
S. Hagg-Holmberg
Turgut Tatlisumak
O. Salonen
J. Putaala
J. Martola
P. H. Groop
Published in Diabetes Care
Volume 42
Issue 2
Pages 327-330
ISSN 0149-5992
Publication year 2019
Published at Institute of Neuroscience and Physiology
Pages 327-330
Language en
Links dx.doi.org/10.2337/dc18-1302
Keywords risk-factors, microbleeds, stroke, retinopathy, prevalence, Endocrinology & Metabolism, ckert t, 1989, diabetologia, v32, p219
Subject categories Endocrinology

Abstract

OBJECTIVETo assess the prevalence of cerebral small-vessel disease (SVD) in subjects with type 1 diabetes compared with healthy control subjects and to characterize the diabetes-related factors associated with SVD.RESEARCH DESIGN AND METHODSThis substudy was cross-sectional in design and included 191 participants with type 1 diabetes and median age 40.0 years (interquartile range 33.0-45.1) and 30 healthy age- and sex-matched control subjects. All participants underwent clinical investigation and brain MRIs, assessed for cerebral SVD.RESULTSCerebral SVD was more common in participants with type 1 diabetes than in healthy control subjects: any marker 35% vs. 10% (P = 0.005), cerebral microbleeds (CMBs) 24% vs. 3.3% (P = 0.008), white matter hyperintensities 17% vs. 6.7% (P = 0.182), and lacunes 2.1% vs. 0% (P = 1.000). Presence of CMBs was independently associated with systolic blood pressure (odds ratio 1.03 [95% CI 1.00-1.05], P = 0.035).CONCLUSIONSCerebral SVD, CMBs in particular, is more common in young people with type 1 diabetes compared with healthy control subjects.

Page Manager: Webmaster|Last update: 9/11/2012
Share:

The University of Gothenburg uses cookies to provide you with the best possible user experience. By continuing on this website, you approve of our use of cookies.  What are cookies?

Denna text är utskriven från följande webbsida:
http://gu.se/english/research/publication/?languageId=100001&disableRedirect=true&returnUrl=http%3A%2F%2Fgu.se%2Fforskning%2Fpublikation%2F%3FpublicationId%3D277877&publicationId=277877
Utskriftsdatum: 2020-01-18