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GlyConnect: Glycoproteomics Goes Visual, Interactive, and Analytical

Journal article
Authors D. Alocci
J. Mariethoz
A. Gastaldello
E. Gasteiger
Niclas G. Karlsson
D. Kolarich
N. H. Packer
F. Lisacek
Published in Journal of Proteome Research
Volume 18
Issue 2
Pages 664-677
ISSN 1535-3893
Publication year 2019
Published at Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology
Pages 664-677
Language en
Links dx.doi.org/10.1021/acs.jproteome.8b...
Keywords data integration, database, software, glycoprotein, glycomics, glycoproteomics, glycan structure, symbol nomenclature, relational database, glycomics, tool, ontology, Biochemistry & Molecular Biology
Subject categories Biological Sciences

Abstract

Knowledge of glycoproteins, their site-specific glycosylation patterns, and the glycan structures that they present to their recognition partners in health and disease is gradually being built on using a range of experimental approaches. The data from these analyses are increasingly being standardized and presented in various sources, from supplemental tables in publications to localized servers in investigator laboratories. Bioinformatics tools are now needed to collect these data and enable the user to search, display, and connect glycomics and glycoproteomics to other sources of related proteomics, genomics, and interactomics information. We here introduce GlyConnect (https://glyconnect.expasy.org/), the central platform of the Glycomics@ExPASy portal for glycoinformatics. GlyConnect has been developed to gather, monitor, integrate, and visualize data in a user-friendly way to facilitate the interpretation of collected glycoscience data. GlyConnect is designed to accommodate and integrate multiple data types as they are increasingly produced.

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Denna text är utskriven från följande webbsida:
http://gu.se/english/research/publication/?publicationId=278447
Utskriftsdatum: 2019-11-12