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3D evaluation of fetal brain structures: reference values and growth curves

Journal article
Authors G. Babucci
Karl Gustaf Rosén
B. Cappuccini
G. Clerici
Published in Journal of Maternal-Fetal and Neonatal Medicine
ISSN 1476-7058
Publication year 2019
Published at Institute of Neuroscience and Physiology
Language en
Links dx.doi.org/10.1080/14767058.2019.16...
Keywords Cerebellum, cortex, thalami, TUI, VOCAL
Subject categories Prenatal and perinatal research

Abstract

Background: The development of the fetal central nervous system is one of the most important fields of research in perinatology. Since the early 1980s, 3 D ultrasound has become one of the major research tools in obstetrics and gynecology. Objective: The aim of this study was to reconstruct thalamus, cerebellum and Cortex volumes of fetal brain and generate, for these volumes, growth curves related to gestational age. Methods: We enrolled 344 pregnant women. Using “Tomographic Ultrasound Imaging” (TUI), in all cases we obtained a satisfying 3 D acquisition of fetal brain. We reconstructed offline thalamus, cerebellum and cortex volumes using “Virtual Organ Computer-Aided AnaLysis” (VOCAL) or 4 D View (GE Healthcare). Results: Among the 344 fetuses examined, we obtained 314 thalamus volumes, 252 cerebellum volumes and 261 cortex volumes and we constructed the reference growth curves. Conclusion: Our study confirms the reliability of cerebral volumes evaluation using 3 D technology and how these cerebral structures grow through gestation. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.

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Denna text är utskriven från följande webbsida:
http://gu.se/english/research/publication/?publicationId=290371
Utskriftsdatum: 2020-08-12