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Diet and exercise weight-loss trial in lactating overweight and obese women

Journal article
Authors Fredrik Bertz
Hilde Kristin Brekke
Lars Ellegård
K. M. Rasmussen
Margareta Wennergren
Anna Winkvist
Published in American Journal of Clinical Nutrition
Volume 96
Issue 4
Pages 698-705
ISSN 0002-9165
Publication year 2012
Published at Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Institute of Clinical Sciences, Department of Obstetrics and Gynecology
Pages 698-705
Language en
Keywords total-energy-expenditure, pregnancy, metaanalysis, retention, adults, gain, Adult, Behavior Therapy, Body Composition, Body Mass Index, Diet Records, Diet, Reducing, Exercise, Female, Follow-Up Studies, Humans, Lactation, Obesity, diet therapy, prevention & control, therapy, Overweight, diet therapy, prevention & control, therapy, Patient Dropouts, Patient Education as Topic, Recurrence, prevention & control, Sweden, Walking, Weight Loss
Subject categories Family Medicine, Public Health, Global Health, Social Medicine and Epidemiology, Nutrition and Dietetics


Background: Current evidence suggests a combined treatment of postpartum weight loss of diet and exercise. However, to our knowledge, neither their separate and interactive effects nor long-term outcomes have been evaluated. Objective: We evaluated whether a 12-wk dietary behavior modification (D) treatment to decrease energy intake, physical exercise behavior modification (E) treatment to implement moderate aerobic exercise, or combined dietary and physical exercise behavior modification (DE) treatment compared with control (usual care) (C) reduces body weight in lactating women measured at the end of treatment and at a 1-y follow-up 9 mo after treatment termination. Design: At 10-14 wk postpartum, 68 lactating Swedish women with a prepregnancy BMI (in kg/m(2)) of 25-35 were randomly assigned to D, E, DE, or C groups. Measurements were made at baseline, after the intervention, and again at a 1-y follow-up 9 mo later. A 2 x 2 factorial approach was used to analyze main and interaction effects of treatments. Results: Weight changes after the intervention and 1-y follow-up were -8.3 +/- 4.2 and -10.2 +/- 5.7 kg, respectively, in the D group; -2.4 +/- 3.2 and -2.7 +/- 5.9 kg, respectively, in the E group; -6.9 +/- 3.0 and -7.3 +/- 6.3 kg, respectively, in the DE group; and -0.8 +/- 3.0 and -0.9 +/- 6.6 kg, respectively, in the C group. The main effects of D treatment, but not of E treatment, on weight were significant at both times (P < 0.001). Conclusions: Dietary treatment provided clinically relevant weight loss in lactating postpartum women, which was sustained at 9 mo after treatment. The combined treatment did not yield significant weight or body-composition changes beyond those of dietary treatment alone. This trial was registered at as NCT01343238. Am J Clin Nutr 2012;96:698-705.

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