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Plasma factor VII-activating protease antigen levels and activity are increased in ischemic stroke.

Journal article
Authors Ellen Hanson
S M Kanse
A Joshi
Katarina Jood
Staffan Nilsson
Christian Blomstrand
Christina Jern
Published in Journal of thrombosis and haemostasis : JTH
Volume 10
Issue 5
Pages 848-56
ISSN 1538-7836
Publication year 2012
Published at Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Department of Mathematical Sciences, Mathematical Statistics
Pages 848-56
Language en
Keywords Adult, Aged, Biological Markers, blood, Brain Ischemia, blood, enzymology, epidemiology, genetics, Case-Control Studies, Female, Genotype, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Phenotype, Polymorphism, Single Nucleotide, Risk Assessment, Risk Factors, Serine Endopeptidases, blood, genetics, Stroke, blood, enzymology, epidemiology, genetics, Sweden, epidemiology, Up-Regulation
Subject categories Neurology, Medical Genetics


Factor VII-activating protease (FSAP) is a recently discovered plasma protease with a role in the regulation of hemostasis and vascular remodeling processes. Higher levels and activity of FSAP have been reported in patients with deep vein thrombosis, but there are no data on plasma FSAP in ischemic stroke (IS).

Page Manager: Webmaster|Last update: 9/11/2012

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