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Functional assessment of high-grade ICA stenosis with duplex ultrasound and transcranial Doppler.

Journal article
Authors Helene Zachrisson
Marita Fouladiun
Christian Blomstrand
Jan Holm
Reinhard Volkmann
Published in Clinical physiology and functional imaging
Volume 32
Issue 3
Pages 241-6
ISSN 1475-097X
Publication year 2012
Published at Institute of Clinical Sciences, Department of Surgery
Institute of Neuroscience and Physiology, Department of Clinical Neuroscience and Rehabilitation
Institute of Neuroscience and Physiology, Department of Physiology
Pages 241-6
Language en
Keywords Adult, Aged, Aged, 80 and over, Blood Flow Velocity, Carotid Artery, Internal, physiopathology, ultrasonography, Carotid Stenosis, physiopathology, ultrasonography, Cerebrovascular Circulation, Circle of Willis, physiopathology, ultrasonography, Collateral Circulation, Female, Hemodynamics, Humans, Magnetic Resonance Angiography, Male, Middle Aged, Predictive Value of Tests, Prognosis, Regional Blood Flow, Retrospective Studies, Severity of Illness Index, Sweden, Ultrasonography, Doppler, Duplex, Ultrasonography, Doppler, Transcranial
Subject categories Clinical Medicine


Duplex ultrasound (DUS) has shown a >90% accuracy compared to angiography, concerning the degree of internal carotid artery (ICA) stenosis. However, uncertainty may occur in a severe stenosis, in which peak systolic velocity (PSV) may decrease owing to high flow resistance or high backward pressure. We investigated intracranial collateral flows using transcranial Doppler (TCD) to further evaluate the hemodynamic significance of high-grade ICA stenosis.

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