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Urinary albumin excretion in healthy adults: a cross sectional study of 24-hour versus timed overnight samples and impact of GFR and other personal characteristics.

Journal article
Authors Peter Fagerstrom
Gerd Sällsten
Magnus Åkerström
Börje Haraldsson
Lars Barregård
Published in BMC nephrology
Volume 16
Issue 1
Pages 8
ISSN 1471-2369
Publication year 2015
Published at Institute of Medicine, Department of Public Health and Community Medicine, Section of Occupational and environmental medicine
Institute of Medicine, Department of Molecular and Clinical Medicine
Pages 8
Language en
Links dx.doi.org/10.1186/1471-2369-16-8
Subject categories Clinical Medicine

Abstract

Urinary albumin can be measured in 24 h or spot samples. The 24 h urinary albumin excretion rate is considered the gold standard, but is cumbersome to collect. Instead, often an overnight sample is collected, and adjusted for dilution. Proxies for 24 h excretion rate have been studied in diabetics, but seldom in healthy individuals. Our aims were to compare 24 h and overnight albumin excretion, to assess the impact of personal characteristics, and to examine correlations between the 24 h excretion rate and proxies such as the albumin to creatinine ratio (ACR).

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