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ICTV Virus Taxonomy Profile: Deltavirus

Journal article
Authors L. Magnius
J. Taylor
W. S. Mason
C. Sureau
P. Deny
Helene Norder
Published in Journal of General Virology
Volume 99
Issue 12
Pages 1565-1566
ISSN 0022-1317
Publication year 2018
Published at Institute of Biomedicine, Department of Infectious Medicine
Pages 1565-1566
Language en
Keywords Deltavirus, ICTV report, taxonomy, hepatitis delta virus, hepatitis, helper virus, hepatitis B virus, hepatitis, antigenome
Subject categories Virology


Hepatitis delta virus, the only member of the only species in the genus Deltavirus, is a unique human pathogen. Its -1.7 kb circular negative-sense RNA genome encodes a protein, hepatitis delta antigen, which occurs in two forms, small and large, both with unique functions. Hepatitis delta virus uses host RNA polymerase II to replicate via double rolling circle RNA synthesis. Newly synthesized linear RNAs are circularized after autocatalytic cleavage and ligation. Hepatitis delta virus requires the envelope of the helper virus, hepatitis B virus (family Hepadnaviridae), to produce infectious particles. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of Deltavirus which is available at

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