Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12
| Författare |
Sebastian Völz Petur Petursson Oskar Angerås Jacob Odenstedt Dan Ioanes Inger Haraldsson Christian Dworeck Geir Hirlekar Björn Redfors Anna Myredal Berglind Libungan Per Albertsson Truls Råmunddal Elmir Omerovic |
|---|---|
| Publicerad i | European heart journal. Acute cardiovascular care |
| ISSN | 2048-8734 |
| Publiceringsår | 2019 |
| Publicerad vid | |
| Språk | en |
| Länkar |
dx.doi.org/10.1177/2048872619877287 www.ncbi.nlm.nih.gov/entrez/query.f... |
| Ämneskategorier | Kardiovaskulär medicin |
Percutaneous coronary intervention (PCI) improves outcomes in non-ST elevation acute coronary syndromes (NSTE-ACSs). Octogenarians, however, were underrepresented in the pivotal trials. This study aimed to assess the effect of PCI in patients ≥80 years old.We used data from the SWEDEHEART registry for all hospital admissions at eight cardiac care centres within Västra Götaland County. Consecutive patients ≥80 years old admitted for NSTE-ACS between January 2000 and December 2011 were included. We performed instrumental variable analysis with propensity score. The primary endpoint was all-cause mortality at 30 days and one year after index hospitalization. During the study period 5200 patients fulfilled the inclusion criteria. In total, 586 (11.2%) patients underwent PCI, the remaining 4613 patients were treated conservatively. Total mortality at 30 days was 19.4% (1007 events) and 39.4% (1876 events) at one year. Thirty-day mortality was 20.7% in conservatively treated patients and 8.5% in the PCI group (adjusted odds ratio 0.34; 95% confidence interval 0.12-0.97, p = 0.044). One-year mortality was 42.1% in the conservatively treated group and 16.3% in the PCI group (adjusted odds ratio 0.97; 95% confidence interval 0.36-2.51, p = 0.847).PCI in octogenarians with NSTE-ACS was associated with a lower risk of mortality at 30 days. However, this survival benefit was not sustained during the entire study-period of one-year.
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