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Författare |
Grethe Jonasson Jack Hilon Bengt Hasséus Torgny Alstad Hossein Kashani |
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Publicerad i | Crohn's & Colitis 360. |
Volym | 1 |
Nummer/häfte | 2 |
Publiceringsår | 2019 |
Publicerad vid |
Institutionen för odontologi Institutionen för odontologi, sektion 1 Institutionen för odontologi, sektion 2 |
Språk | en |
Länkar |
https://doi.org/10.1093/crocol/otz0... |
Ämnesord | bone fracture, colitis, inflammatory bowel disease, osteoporosis |
Ämneskategorier | Medicinska grundvetenskaper |
Background Studies are inconsistent whether people with Crohn disease (CD) have an increased fracture risk. This study showed that patients with Crohn’s disease (CD) had a higher ten year probability of fracture, assessed by the fracture assessment tool FRAX, and more fractures, but the proportion of CD patients with a fracture was not significantly higher than that of controls. Methods Forty-nine CD and 49 controls participated. All 98 completed a health questionnaire. A score with the fracture assessment tool FRAX > 15% was considered risk factor for fracture. Results Mean FRAX score for 49 CD was 10.1 ± 10.3% and for 49 controls 5.0 ± 3.9% (P = 0.002). The variables correlated with fracture were being female (P = 0.04) and having a fractured mother (P = 0.002). Conclusion The CD group had significantly higher FRAX scores and more fractures, but the proportion of CD subjects with a fracture was not significantly higher than that of controls.