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Regional distribution of melanocytic naevi in relation to sun exposure, and site-specific counts predicting total number of naevi.

Artikel i vetenskaplig tidskrift
Författare A Augustsson
Ulrika Stierner
Inger Rosdahl
M Suurküla
Publicerad i Acta dermato-venereologica
Volym 72
Nummer/häfte 2
Sidor 123-7
ISSN 0001-5555
Publiceringsår 1992
Publicerad vid Institutionen för särskilda specialiteter, Avdelningen för dermatologi och venereologi
Institutionen för särskilda specialiteter, Avdelningen för onkologi
Sidor 123-7
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Adult, Female, Humans, Male, Middle Aged, Neoplasms, Radiation-Induced, pathology, Nevus, Pigmented, etiology, pathology, Skin Neoplasms, etiology, pathology, Sunlight, adverse effects
Ämneskategorier Cancer och onkologi

Sammanfattning

The role of exposure to ultraviolet light in the formation of melanocytic naevi was analysed by investigating the regional naevus distribution in 310 subjects (30-50 years) from a Swedish census file. The lateral aspect of the arms and the back had the largest concentration of naevi. The mean naevus count per unit surface area was higher in intermittently exposed than in rarely exposed skin (p less than 0.001), while the lowest mean count was found in chronically exposed skin. These results support the idea that intermittent exposure to ultraviolet light has a "naevogenic" effect while chronic exposure might be protective. Dysplastic naevi had a distribution pattern quite different from common naevi. Considering the distribution pattern solely, dysplastic naevi seem to develop independently of exposure to ultraviolet light. The numbers of naevi in different skin areas were tested for their power in predicting the total body naevus count. The strongest correlations were found between total counts and counts on the anterior surface of the thighs and the lateral aspect of the arms. Counts from any of these areas will provide a practical and satisfactory estimate of the total number of naevi.

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