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Tobacco smoke exposure and pregnancy outcome among working women. A prospective study at prenatal care centers in Orebro County, Sweden

Artikel i vetenskaplig tidskrift
Författare Gunnar Ahlborg
L. Bodin
Publicerad i Am J Epidemiol
Volym 133
Nummer/häfte 4
Sidor 338-47
ISSN 0002-9262 (Print)
Publiceringsår 1991
Publicerad vid Institutionen för samhällsmedicin, Avdelningen för miljömedicin
Institutionen för invärtesmedicin, Avdelningen för internmedicin
Sidor 338-47
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Adult, Female, Humans, Odds Ratio, Pregnancy, Pregnancy Outcome/*epidemiology, Prospective Studies, Questionnaires, Sweden/epidemiology, Tobacco Smoke Pollution/adverse effects/*statistics & numerical data, *Women, Working
Ämneskategorier Reproduktiv hälsa, Folkhälsomedicinska forskningsområden, Yrkesmedicin, Barn

Sammanfattning

Among 4,687 women undergoing prenatal care in Orebro County, Sweden, from October 1980 to June 1983, 678 nonsmokers reported passive exposure to tobacco smoke. Of these women, 267 had been passively exposed at work, and the risk ratio (RR) for intrauterine death (spontaneous abortion or stillbirth) among these pregnancies was increased to 1.53 (95% confidence interval (CI) 0.98-2.38) compared with pregnancies of unexposed working women. This could not be explained by age, previous spontaneous abortion, educational level, planning of pregnancy, or alcohol use. The effect was confined to first-trimester fetal loss (adjusted RR = 2.16, 95% CI 1.23-3.81), while active smoking was associated with intrauterine death after the first trimester. Passive exposure in the workplace was weakly associated with preterm birth (less than 37 weeks) but not with low birth weight (less than 2,500 g) among full-term livebirths. Active smoking clearly increased the risk of both of these outcomes. However, passive exposure in the home only did not seem to affect pregnancy outcome. The lack of quantitative exposure data points to the need for more research before passive exposure to tobacco smoke can be regarded as an established hazard to fetal development and survival.

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