Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

Nitric oxide and release … - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

Nitric oxide and release of the peptide VIP from parasympathetic terminals in the submandibular gland of the anaesthetized cat.

Artikel i vetenskaplig tidskrift
Författare A V Edwards
Gunnar Tobin
Jörgen Ekström
S R Bloom
Publicerad i Experimental physiology
Volym 81
Nummer/häfte 3
Sidor 349-59
ISSN 0958-0670
Publiceringsår 1996
Publicerad vid Institutionen för fysiologi och farmakologi, Avdelningen för farmakologi
Sidor 349-59
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Animals, Arginine, pharmacology, Atropine, pharmacology, Blood Pressure, drug effects, physiology, Cats, Electric Stimulation, Enzyme Inhibitors, administration & dosage, pharmacology, Heart Rate, drug effects, physiology, Injections, Intra-Arterial, Male, NG-Nitroarginine Methyl Ester, administration & dosage, antagonists & inhibitors, pharmacology, Nitric Oxide, physiology, Nitric Oxide Synthase, antagonists & inhibitors, pharmacology, Nitroprusside, pharmacology, Parasympathetic Fibers, Postganglionic, drug effects, physiology, Parasympatholytics, pharmacology, Regional Blood Flow, Saliva, drug effects, Submandibular Gland, blood supply, innervation, physiology, Vascular Resistance, drug effects, Vasoactive Intestinal Peptide, drug effects, secretion
Ämneskategorier Farmakologi

Sammanfattning

The role of nitric oxide (NO) in mediating various submandibular responses to stimulation of the parasympathetic innervation has been investigated in anaesthetized cats, in which N omega-nitro-L-arginine methyl ester (L-NAME; 30 mg kg-1 I.A.) was used to block the synthesis of NO. L-NAME significantly reduced the vasodilator response and the flow of saliva, together with the output of salivary protein that occurred during stimulation of the chorda lingual nerve (20 Hz for 1 s at 10 s intervals), without significantly reducing the output of vasoactive intestinal peptide (VIP) from the gland. The results show that NO is implicated not only in the release of VIP, as established previously, but also in mediating its actions following release in the submandibular gland of the cat.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?