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Plasma platelet factor 4: a potentially useful predictor of ischaemic heart disease?

Artikel i vetenskaplig tidskrift
Författare Jack Kutti
K Svärdsudd
A Sigvaldason
S Safai-Kutti
Hans Wadenvik
Publicerad i Folia haematologica (Leipzig, Germany : 1928)
Volym 110
Nummer/häfte 6
Sidor 868-73
ISSN 0323-4347
Publiceringsår 1983
Publicerad vid Medicinska institutionen
Sidor 868-73
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Adult, Aged, Coronary Disease, blood, Female, Humans, Male, Middle Aged, Myocardial Infarction, blood, Platelet Factor 4, analysis, Prognosis
Ämneskategorier Klinisk medicin

Sammanfattning

The aim was to investigate whether plasma platelet factor 4 (PF-4) in suspected acute myocardial infarction (AMI) patients could serve as a prognostic tool and identify patients at risk for future death from AMI or ischaemic heart disease (IHD). Therefore, upon admission to our coronary care unit plasma PF-4 was measured on 109 consecutive patients. 53 of them proved to have AMI, and 50 IHD but no AMI; the remaining 6 had no evidence of IHD. 24 patients died in hospital or during the follow-up period which was an average of 16.7 +/- 2.4 months. The decreased were subgrouped into those dying of AMI (n = 16), and those dying of IHD but with no AMI (n = 8). No deaths from other causes were recorded. As compared with survivors there was a tendency towards higher PF-4 values among those who died of AMI. However, patients who during follow-up suffered death from IHD proved to have significantly (p less than 0.05) higher PF-4 levels than survivors.

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