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Wheezing bronchitis reinvestigated at the age of 10 years.

Artikel i vetenskaplig tidskrift
Författare Göran Wennergren
Mainor Åmark
Kerstin Åmark
Sólveig Oskarsdóttir
Gunilla M. Sten
Staffan Redfors
Publicerad i Acta paediatrica (Oslo, Norway : 1992)
Volym 86
Nummer/häfte 4
Sidor 351-5
ISSN 0803-5253
Publiceringsår 1997
Publicerad vid Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik
Sidor 351-5
Språk en
Länkar www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Asthma, epidemiology, etiology, Bronchitis, complications, epidemiology, virology, Follow-Up Studies, Histamine, Humans, Hypersensitivity, Immediate, epidemiology, etiology, Infant, Respiratory Sounds, etiology, Respiratory Syncytial Virus Infections, complications, epidemiology, Retrospective Studies, Severity of Illness Index, Sweden, epidemiology, Tobacco Smoke Pollution, adverse effects
Ämneskategorier Pediatrik, Lungmedicin och allergi, Epidemiologi

Sammanfattning

We have reinvestigated 92/101 children aged 10, who before the age of 2 years were admitted to a paediatric ward due to wheezing bronchitis. At the present time, 70% are symptom-free without medication, 20% have mild asthma, 8% moderate and 2% severe asthma. Persistent asthma correlated significantly to the presence of some other atopic disease in recent years, to early start of wheezing during infancy and to intense obstructive disease as a young child, while initial respiratory syncytial virus infection did not. A clear-cut relationship between smoking in the home in infancy and persistent asthma emerged (not visible at a preschool follow-up). The histamine challenge results correlated to the clinical picture. A normal histamine challenge was seen in 63%, mild hyperresponsiveness in 19%, moderate in 12% and pronounced hyperresponsiveness in 6%. The figures for persistent asthma and bronchial hyperresponsiveness are high compared with the prevalence of asthma in the overall population of schoolchildren.

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