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Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden.

Artikel i vetenskaplig tidskrift
Författare Hanna Gyllensten
Andrius Kavaliunas
Kristina Alexanderson
Jan Hillert
Petter Tinghög
Emilie Friberg
Publicerad i Multiple sclerosis journal - experimental, translational and clinical
Volym 4
Nummer/häfte 3
ISSN 2055-2173
Publiceringsår 2018
Publicerad vid Institutionen för vårdvetenskap och hälsa
Språk en
Länkar dx.doi.org/10.1177/2055217318783352
https://journals.sagepub.com/doi/ab...
www.ncbi.nlm.nih.gov/entrez/query.f...
Ämneskategorier Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Neurologi, Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi

Sammanfattning

Population-based estimates of costs of illness and health-related quality of life, by disability levels among people with multiple sclerosis, are lacking.To estimate the annual costs of illness and health-related quality of life, by disability levels, among multiple sclerosis patients, 21-64 years of age.Microdata from Swedish nationwide registers were linked to estimate the prevalence-based costs of illness in 2013, including direct costs (prescription drug use and specialised healthcare) and indirect costs (calculated using sick leave and disability pension), and health-related quality of life (estimated from the EQ-5D). Disability level was measured by the Expanded Disability Status Scale (EDSS).Among 8906 multiple sclerosis patients, EDSS 0.0-3.5 and 7.0-9.5 were associated with mean indirect costs of SEK 117,609 and 461,357, respectively, whereas direct costs were similar between the categories (SEK 117,423 and 102,714, respectively). Prescription drug costs represented 40% of the costs of illness among multiple sclerosis patients with low EDSS, while among patients with high EDSS more than 80% were indirect costs. Among the 1684 individuals who had reported both EQ-5D and EDSS, the lowest health-related quality of life scores were found among those with a high EDSS.Among people with multiple sclerosis, we confirmed higher costs and lower health-related quality of life in higher disability levels, in particular high indirect costs.

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