Till sidans topp

Sidansvarig: Webbredaktion
Sidan uppdaterades: 2012-09-11 15:12

Tipsa en vän
Utskriftsversion

P-cadherin as a marker in… - Göteborgs universitet Till startsida
Webbkarta
Till innehåll Läs mer om hur kakor används på gu.se

P-cadherin as a marker in the differential diagnosis of breast lesions.

Artikel i vetenskaplig tidskrift
Författare Anikó Kovács
R A Walker
Publicerad i Journal of clinical pathology
Volym 56
Nummer/häfte 2
Sidor 139-41
ISSN 0021-9746
Publiceringsår 2003
Publicerad vid Institutionen för laboratoriemedicin , Avdelningen för patologi
Sidor 139-41
Språk en
Länkar dx.doi.org/10.1136/jcp.56.2.139
www.ncbi.nlm.nih.gov/entrez/query.f...
Ämnesord Adenocarcinoma, diagnosis, Biomarkers, Tumor, analysis, Breast Diseases, diagnosis, Breast Neoplasms, diagnosis, Cadherins, analysis, Carcinoma, Intraductal, Noninfiltrating, diagnosis, Diagnosis, Differential, Female, Humans, Neoplasm Proteins, analysis
Ämneskategorier Medicinsk laboratorievetenskap

Sammanfattning

To assess the value of the calcium dependent cell adhesion molecule P-cadherin as a myoepithelial marker in the differential diagnosis of benign and malignant breast lesions.Immunohistochemical analysis of normal breast, sclerotic breast lesions, tubular carcinomas, and ductal carcinoma in situ using a P-cadherin specific antibody and comparison with smooth muscle actin.All myoepithelial cells in normal breast ducts, ductules, and lobules and sclerotic lesions showed strong staining for P-cadherin. There was no staining of tubular carcinomas; myoepithelial cells were demonstrated around in situ carcinomas. Weaker reactivity was seen in a proportion of cells in some hyperplasias and in situ carcinomas. This weak reactivity in these tissues was not seen for smooth muscle actin but in radial scars, tubular carcinomas, and ductal carcinoma in situ staining of stromal cells caused difficulties in the identification of myoepithelial cells.P-cadherin is a useful marker in the differential diagnosis of breast lesions.

Sidansvarig: Webbredaktion|Sidan uppdaterades: 2012-09-11
Dela:

På Göteborgs universitet använder vi kakor (cookies) för att webbplatsen ska fungera på ett bra sätt för dig. Genom att surfa vidare godkänner du att vi använder kakor.  Vad är kakor?