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Oxidized, bioactive implants are rapidly and strongly integrated in bone. Part 1--experimental implants.

Artikel i vetenskaplig tidskrift
Författare Young-Taeg Sul
Yongsoo Jeong
Carina B. Johansson
Tomas Albrektsson
Publicerad i Clinical Oral Implants Research
Volym 17
Nummer/häfte 5
Sidor 521-6
ISSN 0905-7161
Publiceringsår 2006
Publicerad vid Institutionen för kliniska vetenskaper
Sidor 521-6
Språk en
Länkar dx.doi.org/10.1111/j.1600-0501.2005...
Ämnesord Animals, Coated Materials, Biocompatible, chemistry, Crystallography, Dental Implants, Dental Materials, chemistry, Dental Prosthesis Design, Electrochemistry, Electron Probe Microanalysis, Magnesium, chemistry, Microscopy, Electron, Scanning, Osseointegration, physiology, Oxidation-Reduction, Porosity, Rabbits, Stress, Mechanical, Surface Properties, Tibia, surgery, ultrastructure, Time Factors, Titanium, chemistry, Torque, Wound Healing, physiology
Ämneskategorier Biomaterial, Ytbehandlingsteknik, Yt- och kolloidkemi

Sammanfattning

OBJECTIVES: The study presented was designed to investigate the speed and the strength of osseointegration of oxidized implants at early healing times in comparison which machined, turned implants. MATERIAL AND METHODS: Screw-shaped titanium implants were prepared and divided into two groups: magnesium ion incorporated, oxidized implants (Mg implants, n=10) and machined, turned implants (controls, n=10). Mg implants were prepared using micro-arc oxidation methods. Surface oxide properties of implants such as surface chemistry, oxide thickness, morphology/pore characteristics, crystal structures and roughness were characterized with various surface analytic techniques. Implants were inserted into the tibiae of ten New Zealand white rabbits. After a follow-up period of 3 and 6 weeks, removal torque (RTQ), osseointegration speed (DeltaRTQ/Deltahealing time) and integration strength of implants were measured. Bonding failure analysis of the bone-to-implant interface was performed. RESULTS: The speed the and strength of osseointegration of Mg implants were significantly more rapid and stronger than for turned implants at follow-up periods of 3 and 6 weeks. Bonding failure for Mg implants dominantly occurred within the bone tissue, whereas bonding failure for turned implants mainly occurred at the interface between implant and bone. CONCLUSIONS: Oxidized, bioactive implants are rapidly and strongly integrated in bone. The present results indicate that the rapid and strong integration of oxidized, bioactive Mg implants to bone may encompass immediate/early loading of clinical implants.

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