- Hem
- Om universitetet
- Hitta person
- Pierre Åman
Pierre Åman
Seniorforskare
Avdelningen för-
Identification of genomic binding sites and direct target genes for the transcription factor
DDIT3/CHOP
Ayman Osman, Malin Lindén, Tobias Österlund, Christoffer Vannas, Lisa Andersson, Mandy Escobar, Anders Ståhlberg, Pierre Åman
Experimental Cell Research - 2023 -
Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid
liposarcoma
R. Berthold, I. Isfort, C. Erkut, L. Heinst, I. Grunewald, E. Wardelmann, T. Kindler, Pierre Åman, T. G. P. Grunewald, F. Cidre-Aranaz, M. Trautmann, S. Frohling, C. Scholl, W. Hartmann
Oncogenesis - 2022 -
FET fusion oncoproteins interact with BRD4 and SWI/SNF chromatin remodelling complex subtypes in
sarcoma
Malin Lindén, Christoffer Vannas, Tobias Österlund, Lisa Andersson, Ayman Osman, Mandy Escobar, Henrik Fagman, Anders Ståhlberg, Pierre Åman
Molecular Oncology - 2022 -
Different HSP90 Inhibitors Exert Divergent Effect on Myxoid Liposarcoma In Vitro and In
Vivo
Christoffer Vannas, Lisa Andersson, Soheila Dolatabadi, Parmida Ranji, Malin Lindén, Emma Jonasson, Anders Ståhlberg, Henrik Fagman, Pierre Åman
Biomedicines - 2022 -
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid
Liposarcoma
Soheila Dolatabadi, Emma Jonasson, Lisa Andersson, Manuel Luna Santa-María, Malin Lindén, Tobias Österlund, Pierre Åman, Anders Ståhlberg
Frontiers in Oncology - 2022 -
Total mRNA Quantification in Single Cells: Sarcoma Cell
Heterogeneity.
Emma Jonasson, Soheila Dolatabadi, Pierre Åman, Anders Ståhlberg
Cells - 2020 -
IGF2/IGF1R Signaling as a Therapeutic Target in MYB-Positive Adenoid Cystic Carcinomas and Other Fusion Gene-Driven
Tumors
Mattias K Andersson, Pierre Åman, Göran Stenman
Cells - 2019 -
Requirement for YAP1 signaling in myxoid
liposarcoma.
Marcel Trautmann, Ya-Yun Cheng, Patrizia Jensen, Ninel Azoitei, Ines Brunner, Jennifer Hüllein, Mikolaj Slabicki, Ilka Isfort, Magdalene Cyra, Ruth Berthold, Eva Wardelmann, Sebastian Huss, Bianca Altvater, Claudia Rossig, Susanne Hafner, Thomas Simmet, Anders Ståhlberg, Pierre Åman, Thorsten Zenz, Undine Lange, Thomas Kindler, Claudia Scholl, Wolfgang Hartmann, Stefan Fröhling
EMBO molecular medicine - 2019 -
Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid
Liposarcoma
M. Trautmann, M. Cyra, I. Isfort, B. Jeiler, A. Kruger, I. Grunewald, K. Steinestel, B. Altvater, C. Rossig, S. Hafner, T. Simmet, J. Becker, Pierre Åman, E. Wardelmann, S. Huss, W. Hartmann
Molecular Cancer Therapeutics - 2019 -
Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and
Bone
I. Isfort, S. Elges, M. Cyra, R. Berthold, M. Renner, G. Mechtersheimer, Pierre Åman, O. Larsson, N. Ratner, S. Hafner, T. Simmet, C. Schliemann, C. Rossig, U. Dirksen, I. Grunewald, E. Wardelmann, S. Huss, W. Hartmann, M. Trautmann
Scientific Reports - 2019 -
JAK–STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid
liposarcoma
Soheila Dolatabadi, Emma Jonasson, Malin Lindén, Bentolhoda Fereydouni, Karin Bäcksten, Malin Nilsson, Anna Martner, Amin Forootan, Henrik Fagman, Göran Landberg, Pierre Åman, Anders Ståhlberg
International Journal of Cancer - 2019 -
FET family fusion oncoproteins target the SWI/SNF chromatin remodeling
complex
Malin Lindén, Christer Thomsen, Pernilla Grundevik, Emma Jonasson, Daniel Andersson, Rikard Runnberg, Soheila Dolatabadi, Christoffer Vannas, Manuel Luna Santa-María, Henrik Fagman, Anders Ståhlberg, Pierre Åman
EMBO Reports - 2019 -
Identification of inhibitors regulating cell proliferation and FUS-DDIT3 expression in myxoid liposarcoma using combined DNA, mRNA, and protein
analyses.
David Svec, Soheila Dolatabadi, Christer Thomsen, Nicole Cordes, Mark Shannon, Paul A. Fitzpatrick, Göran Landberg, Pierre Åman, Anders Ståhlberg
Laboratory investigation; a journal of technical methods and pathology - 2018 -
A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic
astrocytoma
Tajana Tesan, Josefin Olausson, Annica Wilzén, Magnus Sabel, Katarina Truvé, H. Sjogren, S. Dosa, Birgitta Lannering, F. Enlund, Tommy Martinsson, Pierre Åman, Frida Abel
PLoS ONE - 2017 -
FUS-DDIT3 Fusion Protein-Driven IGF-IR Signaling is a Therapeutic Target in Myxoid
Liposarcoma
M. Trautmann, J. Menzel, C. Bertling, M. Cyra, I. Isfort, K. Steinestel, S. Elges, I. Gunewald, B. Altvater, C. Rossig, S. Frohling, S. Hafner, T. Simmet, Pierre Åman, E. Wardelmann, S. Huss, W. Hartmann
Clinical Cancer Research - 2017 -
Cell Cycle and Cell Size Dependent Gene Expression Reveals Distinct Subpopulations at Single-Cell
Level
Soheila Dolatabadi, J. Candia, Nina Akrap, Christoffer Vannas, Tajana Tesan Tomic, W. Losert, Göran Landberg, Pierre Åman, Anders Ståhlberg
Frontiers in Genetics - 2017 -
HSP90 inhibition blocks ERBB3 and RET phosphorylation in myxoid/round cell liposarcoma and causes massive cell death in vitro and in
vivo
Setareh Safavi, Sofia Järnum, Christoffer Vannas, Sameer Udhane, Emma Jonasson, Tajana Tesan Tomic, Pernilla Grundevik, Henrik Fagman, Magnus Hansson, Zeynep Kalender, Alexandra Jauhiainen, Soheila Dolatabadi, E. W. Stratford, O. Myklebost, M. Eriksson, Göran Stenman, R. S. Stock, Anders Ståhlberg, Pierre Åman
OncoTarget - 2016 -
Establishment and characterization of a new human myxoid liposarcoma cell line (DL-221) with the FUS-DDIT3
translocation
M. A. de Graaff, J. S. E. Yu, H. C. Beird, D. R. Ingram, T. Nguyen, J. J. Liu, S. Bolshakov, K. Szuhai, Pierre Åman, K. E. Torres, D. Lev, T. O. Nielsen, Jvmg Bovee, A. J. Lazar, N. Somaiah
Laboratory Investigation - 2016 -
Regulatory mechanisms, expression levels and proliferation effects of the FUS-DDIT3 fusion oncogene in
liposarcoma.
Pierre Åman, Soheila Dolatabadi, David Svec, Emma Jonasson, Setareh Safavi, Daniel Andersson, Pernilla Grundevik, Christer Thomsen, Anders Ståhlberg
The Journal of pathology - 2016 -
HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to
vorinostat.
Michaela Angelika Ihle, Sabine Merkelbach-Bruse, Wolfgang Hartmann, Sebastian Bauer, Nancy Ratner, Hiroshi Sonobe, Jun Nishio, Olle Larsson, Pierre Åman, Florence Pedeutour, Takahiro Taguchi, Eva Wardelmann, Reinhard Buettner, Hans-Ulrich Schildhaus
The journal of pathology. Clinical research - 2016 -
SRC inhibition represents a potential therapeutic strategy in
liposarcoma
E. Sievers, M. Trautmann, D. Kindler, S. Huss, I. Gruenewald, U. Dirksen, M. Renner, G. Mechtersheimer, F. Pedeutour, Pierre Åman, J. Nishio, H. U. Schildhaus, J. Kirfel, P. Schirmacher, E. Wardelmann, R. Buettner, W. Hartmann
International Journal of Cancer - 2015 -
Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid
liposarcoma
S. Steinmann, H. Gali-Muhtasib, K. Huebner, R. Al-Halabi, R. Abou Merhi, Pierre Åman, A. Agaimy, F. Haller, R. Schneider-Stock
Cancer Letters - 2015 -
Comparison of reverse transcription quantitative real-time PCR, flow cytometry, and immunohistochemistry for detection of monoclonality in
lymphomas.
Anders Ståhlberg, Pierre Åman, Linda Strömbom, Neven Zoric, Alfredo Diez, Olle Nilsson, Mikael Kubista, Börje Ridell
ISRN oncology - 2014 -
Normal and Functional TP53 in Genetically Stable Myxoid/Round Cell
Liposarcoma
Anders Ståhlberg, Christina Kåbjörn-Gustafsson, Katarina Engström, Christer Thomsen, Soheila Dolatabadi, Emma Jonasson, C. Y. Li, D. Ruff, S. M. Chen, Pierre Åman
Plos One - 2014 -
Cell Senescence in Myxoid/Round Cell
Liposarcoma
Christina Kåbjörn-Gustafsson, Anders Ståhlberg, Katarina Engström, Anna Danielsson, Ingela Turesson, Pierre Åman
Sarcoma - 2014 -
DDIT3 Expression in Liposarcoma
Development
Christina Kåbjörn-Gustafsson, Katarina Engström, Pierre Åman
Sarcoma - 2014 -
A conserved N-terminal motif is required for complex formation between FUS, EWSR1, TAF15 and their oncogenic fusion
proteins.
Christer Thomsen, Pernilla Grundevik, Per Elias, Anders Ståhlberg, Pierre Åman
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2013 -
Fused in sarcoma (FUS) interacts with the cytolinker protein plectin: implications for FUS subcellular localization and
function.
Christer Thomsen, Sameer Udhane, Rikard Runnberg, Gerhard Wiche, Anders Ståhlberg, Pierre Åman
Experimental cell research - 2012 -
Distinct cytoplasmic and nuclear functions of the stress induced protein
DDIT3/CHOP/GADD153
Alexandra Jauhiainen, Christer Thomsen, Linda Strömbom, Pernilla Grundevik, Carola Andersson, Anna Danielsson, Mattias K Andersson, Olle Nerman, Linda Rörkvist, Anders Ståhlberg, Pierre Åman
PLoS ONE - 2012 -
Quantitative PCR Analysis of DNA, RNAs, and Proteins in the Same Single
Cell.
Anders Ståhlberg, Christer Thomsen, David Ruff, Pierre Åman
Clinical chemistry - 2012 -
The first European interdisciplinary ewing sarcoma research
summit.
Heinrich Kovar, Javier Alonso, Pierre Åman, Dave N T Aryee, Jozef Ban, Sue A Burchill, Stefan Burdach, Enrique De Alava, Olivier Delattre, Uta Dirksen, Argyro Fourtouna, Simone Fulda, Lee J Helman, David Herrero-Martin, Pancras C W Hogendoorn, Udo Kontny, Elizabeth R Lawlor, Stephen L Lessnick, Antonio Llombart-Bosch, Markus Metzler, Richard Moriggl, Stephan Niedan, Jenny Potratz, Françoise Redini, Günther H S Richter, Lucia T Riedmann, Claudia Rossig, Beat W Schäfer, Raphaela Schwentner, Katia Scotlandi, Poul H Sorensen, Martin S Staege, Franck Tirode, Jeffrey Toretsky, Selena Ventura, Angelika Eggert, Ruth Ladenstein
Frontiers in oncology - 2012 -
Single-cell gene-expression profiling and its potential diagnostic
applications.
Anders Ståhlberg, Mikael Kubista, Pierre Åman
Expert review of molecular diagnostics - 2011 -
Nuclear expression of FLT1 and its ligand PGF in FUS-DDIT3 carrying myxoid liposarcomas suggests the existence of an intracrine signaling
loop.
Mattias K Andersson, Melker Göransson, Anita Olofsson, Carola Andersson, Pierre Åman
BMC cancer - 2010 -
DDIT3/CHOP and the sarcoma fusion oncoprotein FUS-DDIT3/TLS-CHOP bind cyclin-dependent kinase
2.
Christoffer Bento, Mattias K Andersson, Pierre Åman
BMC cell biology - 2009 -
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast
cancer.
R Shah, P Smith, C Purdie, P Quinlan, L Baker, Pierre Åman, A M Thompson, T Crook
British journal of cancer - 2009 -
Expression of the class I interferon-related MxA protein in temporal arteries in polymyalgia rheumatica and temporal
arteritis.
Claes Nordborg, K Larsson, Pierre Åman, Elisabeth Nordborg
Scandinavian journal of rheumatology - 2009 -
Trabectedin (ET-743) promotes differentiation in myxoid liposarcoma
tumors.
Claudia Forni, Mario Minuzzo, Emanuela Virdis, Elena Tamborini, Matteo Simone, Michele Tavecchio, Eugenio Erba, Federica Grosso, Alessandro Gronchi, Pierre Åman, Paolo Casali, Maurizio D'Incalci, Silvana Pilotti, Roberto Mantovani
Molecular cancer therapeutics - 2009 -
The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with
NFKBIZ.
Melker Göransson, Mattias K Andersson, C Forni, Anders Ståhlberg, Carola Andersson, A. Olofsson, R Mantovani, Pierre Åman
Oncogene - 2009 -
Proliferation of Ewing sarcoma cell lines is suppressed by the receptor tyrosine kinase inhibitors gefitinib and
vandetanib
Mattias K Andersson, Pierre Åman
Cancer Cell International - 2008 -
The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress
response
Mattias K Andersson, Anders Ståhlberg, Yvonne Arvidsson, Anita Olofsson, Henrik Semb, Göran Stenman, Ola Nilsson, Pierre Åman
BMC Cell Biology - 2008 -
Characterization of the 12q amplicons by high-resolution, oligonucleotide array CGH and expression analyses of a novel liposarcoma cell
line
Fredrik Persson, Anita Olofsson, Helene Sjögren, Nihal Chebbo, Bengt E Nilsson, Göran Stenman, Pierre Åman
Cancer Letters - 2008 -
Tissue and cell specific expression patterns of the proto-oncogenic FUS, EWS and TAF15
ribonucleoproteins
Mattias K Andersson, Yvonne Arvidsson, Anita Olofsson, Göran Stenman, Ola Nilsson, Pierre Åman
Molecular Targets for Cancer, Whistler Resort, Whistler, British Columbia, Canada - 2007 -
TET family proteins localize to stress granules upon abnormal protein
expression
Mattias K Andersson, Pierre Åman
Protein Synthesis and Translational Control, EMBL, Heidelberg, Germany - 2007 -
Irradiation of myxoid/round cell liposarcoma induces volume reduction and lipoma-like
morphology.
Katarina Engström, Peter Bergh, C. G. Cederlund, Ragnar Hultborn, Helena Willen, Pierre Åman, Lars-Gunnar Kindblom, Jeanne Meis-Kindblom
Acta oncologica (Stockholm, Sweden) - 2007 -
Tissue distribution and cellular localization of the three RNA-binding proteins FUS, EWS and TAF15, identified as components of the large Drosha microprocessor
complex
Mattias K Andersson, Pierre Åman
Symposium LXXI: Regulatory RNAs, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, U.S.A. - 2006 -
The myxoid/round cell liposarcoma fusion oncogene FUS-DDIT3 and the normal DDIT3 induce a liposarcoma phenotype in transfected human fibrosarcoma
cells.
Katarina Engström, Helena Willén, Christina Kåbjörn-Gustafsson, Carola Andersson, Marita Olsson, Melker Göransson, Sofia Järnum, Anita Olofsson, Elisabet Warnhammar Finnborg, Pierre Åman
The American journal of pathology - 2006 -
Myxoid liposarcoma FUS-DDIT3 fusion oncogene induces C/EBP β-mediated interleukin 6
expression
Melker Göransson, Erik Elias, Anders Ståhlberg, Anita Olofsson, Carola Andersson, Pierre Åman
International Journal of Cancer - 2005 -
Functional studies of fusion oncogenes associated with the EWS family of
sarcomas
Mattias K Andersson, Anita Olofsson, Pierre Åman
Cancer and Development, Fairmont Banff Springs, Banff, Alberta, Canada - 2005 -
Cell-type-specific expression of p53 and p21 in giant cell
arteritis.
Claes Nordborg, Pierre Åman, M Persson, Elisabeth Nordborg
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 2005 -
Skadade stamceller ger cancer hos
unga
Mattias K Andersson, Pierre Åman
Forskning & Framsteg - 2005 -
Fusion
oncogenes.
Pierre Åman
Seminars in cancer biology - 2005 -
Oncostatin M signaling in human glioma cell
lines.
Annika Krona, Sofia Järnum, Leif G Salford, Bengt Widegren, Pierre Åman
Oncology reports - 2005 -
Quantitative real-time PCR for cancer detection: the lymphoma
case.
Anders Ståhlberg, Neven Zoric, Pierre Åman, Mikael Kubista
Expert review of molecular diagnostics - 2005 -
Fusion oncogenes in tumor
development.
Pierre Åman
Seminars in cancer biology - 2005 -
Large-cell medulloblastoma in Aicardi syndrome. Case report and literature
review.
L Palmér, Claes Nordborg, Karin Steneryd, Pierre Åman, Mårten Kyllerman
Neuropediatrics - 2004 -
Translocated in liposarcoma (TLS) is a substrate for fibroblast growth factor
receptor-1.
Peter Klint, Ulf Hellman, Christer Wernstedt, Pierre Åman, David Ron, Lena Claesson-Welsh
Cellular signalling - 2004 -
Abnormal expression of cell cycle regulators in FUS-CHOP carrying
liposarcomas.
Anita Olofsson, Helena Willén, Melker Göransson, Katarina Engström, Jeanne Meis-Kindblom, Göran Stenman, Lars-Gunnar Kindblom, Pierre Åman
International journal of oncology - 2004 -
LEPREL1, a novel ER and Golgi resident member of the Leprecan
family.
Sofia Järnum, Christian Kjellman, Anna Darabi, Ingar Nilsson, Klaus Edvardsen, Pierre Åman
Biochemical and biophysical research communications - 2004 -
Quantitative real-time PCR method for detection of B-lymphocyte monoclonality by comparison of κ and λ immunoglobulin light chain
expression
Anders Ståhlberg, Pierre Åman, Börje Ridell, Petter Mostad, Mikael Kubista
Clinical Chemistry - 2003 -
The complexity of KIT gene mutations and chromosomal rearrangements and their clinical correlations in gastrointestinal stromal (pacemaker cell)
tumors
Johanna Andersson, Helene Sjögren, Jeanne Meis-Kindblom, Göran Stenman, Pierre Åman, Lars-Gunnar Kindblom
American Journal of Pathology - 2002