Sören Riis Paludan

ER stress induces caspase-2-tBID-GSDMEdependent cell death in neurons lytically infected with herpes simplex virus type

Fanghui Ren, Ryo Narita, Ahmad S. Rashidi, Stefanie Fruhwürth, Zongliang Gao, Rasmus O. Bak, Martin K. Thomsen, Georges M. G. M. Verjans, Line S. Reinert, Sören R Paludan
EMBO JOURNAL - 2023

An IKBKE variant conferring functional cGAS/STING pathway deficiency and susceptibility to recurrent HSV-2

meningitis.

Azadeh Reyahi, Marie Studahl, Morten K Skouboe, Stefanie Fruhwürth, Ryo Narita, Fanghui Ren, Moa Bjerhem Viklund, Marie B Iversen, Mette Christiansen, Alexandra Svensson, Trine H Mogensen, Kristina Eriksson, Sören R Paludan
JCI insight - 2023

TREM2 is down-regulated by HSV1 in microglia and involved in antiviral defense in the

brain

Stefanie Fruhwürth, L. S. Reinert, Carl Öberg, Marcelina Sakr, M. Henricsson, Henrik Zetterberg, Sören R Paludan
Science Advances - 2023

The presence of serum anti-SARS-CoV-2 IgA appears to protect primary health care workers from

COVID-19.

Viktoria Hennings, Karolina Thörn, Sofie Albinsson, Christine Lingblom, Kerstin Andersson, Christer Andersson, Katarina Järbur, Rille Pullerits, Manja Idorn, Sören R Paludan, Kristina Eriksson, Christine Wennerås
European journal of immunology - 2022

Constitutive and latent immune mechanisms exert 'silent' control of virus infections in the central nervous

system

Sören R Paludan, T. H. Mogensen
Current Opinion in Immunology - 2021

Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical

Neurons

Petra Bergström, Edward Trybala, Charlotta Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widehn, Stefanie Fruhwürth, W. Michno, Faisal Hayat Nazir, Jörg Hanrieder, Sören R Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström
Viruses-Basel - 2021

Constitutive immune mechanisms: mediators of host defence and immune

regulation

Sören R Paludan, T. Pradeu, S. L. Masters, T. H. Mogensen
Nature Reviews Immunology - 2021

Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in

humans

A. S. Hait, D. Olagnier, V. Sancho-Shimizu, K. A. Skipper, M. Helleberg, S. M. Larsen, C. Bodda, L. I. Moldovan, F. H. Ren, N. S. B. Andersen, M. M. Thomsen, M. R. Freytag, S. Darmalinggam, I. Parkes, D. D. Kadekar, S. H. Rahbek, D. van der Horst, L. S. Kristensen, Kristina Eriksson, J. Kjems, S. Mostowy, M. Christiansen, J. G. Mikkelsen, C. T. Brandt, Sören R Paludan, T. H. Mogensen
Science Immunology - 2020

HSV1 VP1-2 deubiquitinates STING to block type I interferon expression and promote brain

infection

C. Bodda, L. S. Reinert, Stefanie Fruhwürth, T. Richardo, C. Sun, B. C. Zhang, M. Kalamvoki, A. Pohlmann, T. H. Mogensen, Petra Bergström, Lotta Agholme, P. O'Hare, B. Sodeik, M. Gyrd-Hansen, Henrik Zetterberg, Sören R Paludan
The Journal of experimental medicine - 2020

HSV-1 triggers paracrine fibroblast growth factor response from cortical brain cells via immediate-early protein

ICP0

N. Hensel, V. Raker, B. Forthmann, N. T. Detering, S. Kubinski, A. Buch, G. Katzilieris-Petras, J. Spanier, V. Gudi, S. Wagenknecht, V. Kopfnagel, T. A. Werfel, M. Stangel, A. Beineke, U. Kalinke, Sören R Paludan, B. Sodeik, P. Claus
Journal of Neuroinflammation - 2019

DNA-stimulated cell death: implications for host defence, inflammatory diseases and

cancer

Sören R Paludan, L. S. Reinert, V. Hornung
Nature Reviews Immunology - 2019

RNA Polymerase III as a Gatekeeper to Prevent Severe VZV

Infections

M. E. Carter-Timofte, Sören R Paludan, T. H. Mogensen
Trends in Molecular Medicine - 2018

Sören Riis Paludan

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