Bild
Per Lindahl in SCCR laboratory.
Forskargruppledaren Per Lindahl i SCCR laboratorium.
Foto: Johan Wingborg
Länkstig

Grupp Per Lindahl

Forskningsgrupp
Pågående forskning
Projektägare
Institutionen för biomedicin

Kort beskrivning

Forskning om pro-oxidanta behandlingsmetoder.

Sammanfattning av forskning

Se engelsk version av sidan.

Forskningsverktyg och resurser

Se engelsk version av sidan.

Nuvarande gruppmedlemmar

Per Lindahl, Professor, Forskargruppledare
Nadia Gul, Forskare/Postdoc
Viktor Garellick, Doktorand

Utvalda publikationer

  1. Antioxidants Promote Intestinal Tumor Progression in Mice.
    Zou ZV, Le Gal K, El Zowalaty AE, Pehlivanoglu LE, Garellick V, Gul N, Ibrahim MX, Bergh PO, Henricsson M, Wiel C, Akyürek LM, Bergo MO, Sayin VI, Lindahl P. Antioxidants (Basel). 2021 Feb 4;10(2):241.
     
  2. Knockout of the RAS endoprotease RCE1 accelerates myeloid leukemia by downregulating GADD45b.
    Karlsson C, Akula MK, Staffas A, Cisowski J, Sayin VI, Ibrahim MX, Lindahl P, Bergo MO. Leukemia. 2021 Feb;35(2):606-609.
     
  3. Genomic profiling of the transcription factor Zfp148 and its impact on the p53 pathway. 
    Zou ZV, Gul N, Lindberg M, Bokhari AA, Eklund EM, Garellick V, Patel AAH, Dzanan JJ, Titmuss BO, Le Gal K, Johansson I, Tivesten Å, Forssell-Aronsson E, Bergö MO, Staffas A, Larsson E, Sayin VI, Lindahl P. Sci Rep. 2020 Aug 25;10(1):14156.
     
  4. The MTH1 inhibitor TH588 is a microtubule-modulating agent that eliminates cancer cells by activating the mitotic surveillance pathway.
    Gul N, Karlsson J, Tängemo C, Linsefors S, Tuyizere S, Perkins R, Ala C, Zou Z, Larsson E, Bergö MO, and Lindahl P. Sci Rep. 2019 Oct 11;9(1):14667.
     
  5. BACH1 Stabilization by Antioxidants Stimulates Lung Cancer Metastasis.
    Wiel C, Le Gal K, Ibrahim MX, Jahangir CA, Kashif M, Yao H, Ziegler DV, Xu X, Ghosh T, Mondal T, Kanduri C, Lindahl P, Sayin VI, Bergo MO. Cell. 2019 Jul 11;178(2):330-345.e22.
     
  6. Targeting Zfp148 activates p53 and reduces tumor initiation in the gut.
    Nilton A, Sayin VI, Zou ZV, Sayin SI, Bondjers C, Gul N, Agren P, Fogelstrand P, Nilsson O, Bergo MO, Lindahl P. Oncotarget. 2016 Aug 30;7(35):56183-56192.
     
  7. Antioxidants can increase melanoma metastasis in mice.
    Le Gal K, Ibrahim MX, Wiel C, Sayin VI, Akula MK, Karlsson C, Dalin MG, Akyürek LM, Lindahl P, Nilsson J, Bergo MO. Sci Transl Med. 2015 Oct 7;7(308):308re8.
     
  8. Loss of one copy of Zfp148 reduces lesional macrophage proliferation and atherosclerosis in mice by activating p53.
    Sayin VI, Khan OM, Pehlivanoglu LE, Staffas A, Ibrahim MX, Asplund A, Agren P, Nilton A, Bergström G, Bergo MO, Borén J, Lindahl P. Circ Res. 2014 Oct 10;115(9):781-9.
     
  9. Antioxidants accelerate lung cancer progression in mice.
    Sayin VI, Ibrahim MX, Larsson E, Nilsson JA, Lindahl P*, Bergo MO*. Sci Transl Med. 2014 Jan 29;6(221):221ra15. *corresponding authors.
     
  10. Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment.
    Sayin VI, Nilton A, Ibrahim MX, Ågren P, Larsson E, Petit MM, Hultén LM, Ståhlman M, Johansson BR, Bergo MO, Lindahl P. PLoS One. 2013;8(2):e55720.

Fler publikationer från grupp Per Lindahl på PubMed

Per Lindahl
Foto: Johan Wingborg

Kontaktinformation

Per Lindahl

E-post: Per Lindahl

Besöksadress:
Sahlgrenska Centrum
för Cancerforskning,
Medicinaregatan 1F
413 90 Göteborg