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- Karin Manhem
Karin Manhem
Professor emerita
Avd för molekylär och klinisk medicinOm Karin Manhem
Professor, Överläkare
Kardiovaskulär prevention med intresse framförallt för hypertoni. Registerstudier och kohortstudier kring hypertoni och dess följdsjukdomar.
Bakgrund
- 2014 - professor i internmedicin, Institutionen för Medicin, Sahlgrenska akademin, Göteborgs universitet
- 1983- läkare Medicinkliniken, Sahlgrenska Universitetssjukhuset, Östra, Mölndal och Sahlgrenska. F.n. överläkare medicinkliniken Sahlgrenska.
- 2003 Docent, internmedicin. Göteborgs universitet
- 1996 Specialist kardiologi
- 1992 Medicine doktor
- 1988 Specialist internmedicin
- 1982 leg läkare
- 1980 läkarexamen Göteborgs universitet
Undervisning
Ingår i kursledningen för kursen i internmedicin, läkarprogrammet sedan 1995, samt i programledningen för läkarprogrammet sedan 2011.
Forskningsintresse
Kardiovaskulär epidemiologi med intresse framförallt för hypertoni, kohortstudier, registerstudier.
Läs mer om Karin Manhem och hennes forskning här (på engelska).
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High blood pressure in the emergency department as an opportunistic screening tool for detection of
hypertension.
Sara Bentzel, Karin Manhem, Ottilia Öhman, Karzan Abdulla, Georgios Mourtzinis
Journal of human hypertension - 2024 -
Long-term secondary prevention and outcome following acute coronary syndrome: Real-world results from the Swedish Primary Care Cardiovascular Database
(SPCCD)
Sara Bentzel, Charlotta Ljungman, Per Hjerpe, Linus Schiöler, Karin Manhem, Kristina Bengtsson Boström, Thomas Kahan, Georgios Mourtzinis
European journal of preventive cardiology - 2024 -
Improving cardiovascular control in a hypertensive population in primary care. Results from a staff training
intervention
Rebecka Quester, Staffan Bjorck, Karin Manhem, Jonatan Natman, Susanne Andersson, Per Hjerpe
SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE - 2024 -
Hypertension: sex-related differences in drug treatment, prevalence and blood pressure control in primary
care.
Johan-Emil Bager, Karin Manhem, Tobias Andersson, Per Hjerpe, Kristina Bengtsson Boström, Charlotta Ljungman, Georgios Mourtzinis
Journal of human hypertension - 2023 -
The association between peripheral arterial disease and risk for hip fractures in elderly men is not explained by low hip bone mineral density. Results from the MrOS Sweden
study
Tove Bokrantz, Karin Manhem, Mattias Lorentzon, M. Karlsson, O. Ljunggren, Claes Ohlsson, Dan Mellström
Osteoporosis International - 2022 -
Obesity, overweight and risk for cardiovascular disease and mortality in young
women
Pigi Dikaiou, Lena Björck, Martin Adiels, Christina Lundberg, Zacharias Mandalenakis, Karin Manhem, Annika Rosengren
European Journal of Preventive Cardiology - 2021 -
Blood pressure levels and risk of haemorrhagic stroke in patients with atrial fibrillation and oral anticoagulants: results from The Swedish Primary Care Cardiovascular Database of
Skaraborg.
Johan-Emil Bager, Per Hjerpe, Linus Schiöler, Kristina Bengtsson Boström, Thomas Kahan, Helena Ödesjö, Katarina Jood, Jan Hasselström, Charlotta Ljungman, Karin Manhem, Georgios Mourtzinis
Journal of hypertension - 2021 -
Country of birth and mortality risk in hypertension with and without diabetes: the Swedish primary care cardiovascular
database.
Tobias Andersson, Miriam Pikkemaat, Linus Schiöler, Per Hjerpe, Axel C Carlsson, Per Wändell, Karin Manhem, Thomas Kahan, Kristina Bengtsson Boström
Journal of hypertension - 2021 -
Socioeconomic status affects achievement of blood pressure target in hypertension: contemporary results from the Swedish primary care cardiovascular
database.
Georgios Mourtzinis, Karin Manhem, Thomas Kahan, Linus Schiöler, Jetish Isufi, Charlotta Ljungman, Tobias Andersson, Per Hjerpe
Scandinavian journal of primary health care - 2021 -
Adherence to lipid-lowering guidelines for secondary prevention and potential reduction in CVD events in Swedish primary care: a cross-sectional
study
Helena Ödesjö, S. Bjorck, S. Franzen, Per Hjerpe, Karin Manhem, Annika Rosengren, Jörgen Thorn, Samuel Adamsson Eryd
Bmj Open - 2020 -
Antihypertensive drug classes and the risk of hip fracture: results from the Swedish primary care cardiovascular
database.
Tove Bokrantz, Linus Schiöler, Kristina Bengtsson Boström, Thomas Kahan, Dan Mellström, Charlotta Ljungman, Per Hjerpe, Jan Hasselström, Karin Manhem
Journal of hypertension - 2020 -
The impact of diabetes, education and income on mortality and cardiovascular events in hypertensive patients: A cohort study from the Swedish Primary Care Cardiovascular Database
(SPCCD).
Tobias Andersson, Miriam Pikkemaat, Linus Schiöler, Per Hjerpe, Axel C Carlsson, Per Wändell, Karin Manhem, Thomas Kahan, Jan Hasselström, Kristina Bengtsson Boström
PloS one - 2020 -
Visit patterns at primary care centres and individual blood pressure level - a cross-sectional
study
Helena Ödesjö, Samuel Adamsson Eryd, S. Franzen, Per Hjerpe, Karin Manhem, Annika Rosengren, Jörgen Thorn, S. Bjorck
Scandinavian Journal of Primary Health Care - 2019 -
Treatment of hypertension in old patients without previous cardiovascular
disease.
Johan-Emil Bager, Per Hjerpe, Karin Manhem, Staffan Björck, Stefan Franzén, Annika Rosengren, Samuel Adamsson Eryd
Journal of hypertension - 2019 -
Meta-analyses and blood pressure
goals
Karin Manhem, Annika Rosengren, Samuel Adamsson Eryd
The Journal of Clinical Hypertension - 2018 -
Links between blood pressure and medication intake, well-being, stress, physical activity and symptoms reported via a mobile phone-based self-management support system: a cohort study in primary
care
Charles Taft, Inger Hallberg, Ulrika Bengtsson, Karin Manhem, Karin I Kjellgren
BMJ Open - 2018 -
Primary aldosteronism and thyroid disorders in atrial fibrillation: A Swedish nationwide case-control
study
Georgios Mourtzinis, Samuel Adamsson Eryd, Annika Rosengren, Lena Björck, Martin Adiels, Gudmundur Johannsson, Karin Manhem
European Journal of Preventive Cardiology - 2018 -
Mortality trends and cause of death in patients with new-onset type 2 diabetes and controls: A 24-year follow-up prospective cohort
study.
Tobias Andersson, Per Hjerpe, Axel C Carlsson, Aldina Pivodic, Per Wändell, Karin Manhem, Kristina Bengtsson Boström
Diabetes research and clinical practice - 2018 -
Cardiovascular outcome in treatment-resistant hypertension: results from the Swedish Primary Care Cardiovascular Database
(SPCCD).
Lina Holmqvist, Kristina B Boström, Thomas Kahan, Linus Schiöler, Jan Hasselström, Per Hjerpe, Björn Wettermark, Karin Manhem
Journal of hypertension - 2018 -
Acute blood pressure levels and long-term outcome in ischemic
stroke.
Johan-Emil Bager, Clara Hjalmarsson, Karin Manhem, Björn Andersson
Brain and behavior - 2018 -
Relation Between Lipid Profile and New-Onset Atrial Fibrillation in Patients With Systemic Hypertension (From the Swedish Primary Care Cardiovascular Database SPCCD
)
Georgios Mourtzinis, T. Kahan, K. B. Bostrom, Linus Schiöler, L. C. Wallin, P. Hjerpe, J. Hasselstrom, Karin Manhem
American Journal of Cardiology - 2018 -
Drug adherence in treatment resistant and in controlled hypertension - Results from the Swedish Primary Care Cardiovascular Database
(SPCCD)
Lina Holmqvist, K. B. Bostrom, T. Kahan, Linus Schiöler, M. Qvarnstrom, B. Wettermark, P. Hjerpe, J. Hasselstrom, Karin Manhem
Pharmacoepidemiology and Drug Safety - 2018 -
Improved treatment and control of hypertension in Swedish primary care: results from the Swedish primary care cardiovascular
database
C. Holmquist, J. Hasselstrom, K. B. Bostrom, Karin Manhem, B. Wettermark, P. Hjerpe, T. Kahan
Journal of Hypertension - 2017 -
Aldosterone to Renin Ratio as a Screening Instrument for Primary Aldosteronism in a Middle-Aged Population with Atrial
Fibrillation.
Georgios Mourtzinis, Ahmad Ebrahimi, Helena Gustafsson, Gudmundur Johannsson, Karin Manhem
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme - 2017 -
Antihypertensive Control and Control and new-onset atrial fibrillation: Results from the Swedish Primary Care Cardiovascular Database
(SPCCD)
Georgios Mourtzinis, Linus Schiöler, T Kahan, Kristina Bengtsson Boström, P Hjerpe, J Hasselström, Karin Manhem
European Journal of Preventive Cardiology - 2017 -
Non-steroidal anti-inflammatory drugs and blood pressure control in patients treated for hypertension: results from the Swedish primary care cardiovascular
database.
Charlotta Ljungman, Thomas Kahan, Linus Schiöler, Björn Wettermark, Kristina B Boström, Jan Hasselström, Per Hjerpe, Karin Manhem
Blood pressure - 2017 -
Thiazide diuretics and the risk of osteoporotic fractures in hypertensive patients. Results from the Swedish Primary Care Cardiovascular
Database.
Tove Bokrantz, Charlotta Ljungman, Thomas Kahan, Kristina B Boström, Jan Hasselström, Per Hjerpe, Dan Mellström, Linus Schiöler, Karin Manhem
Journal of hypertension - 2017 -
Reply.
Tove Bokrantz, Charlotta Ljungman, Dan Mellström, Kristina Bengtsson Boström, Karin Manhem
Journal of hypertension - 2017 -
Hypertoni
Karin Manhem
Kvinnohjärtan Red: K Schenk-Gustafsson & N Johnston-Holmström - 2017 -
Persistence to antihypertensive drug classes: A cohort study using the Swedish Primary Care Cardiovascular Database
(SPCCD)
M. Qvarnstrom, T. Kahan, H. Kieler, L. Brandt, J. Hasselstrom, K. B. Bostrom, Karin Manhem, P. Hjerpe, B. Wettermark
Medicine - 2016 -
Blood Pressure Response to Losartan and CPAP in Hypertension and Obstructive Sleep
Apnea
Erik Thunström, Karin Manhem, Annika Rosengren, Yüksel Peker
American journal of respiratory and critical care medicine - 2016 -
Blood pressure and complications in individuals with type 2 diabetes and no previous cardiovascular disease: national population based cohort
study
Samuel Adamsson Eryd, Soffia Gudbjörnsdottir, Karin Manhem, Annika Rosengren, A. M. Svensson, Mervete Miftaraj, S. Franzen, S. Bjorck
Bmj-British Medical Journal - 2016 -
Neuroendocrine and Inflammatory Responses to Losartan and Continuous Positive Airway Pressure in Patients with Hypertension and Obstructive Sleep Apnea A Randomized Controlled
Trial
Erik Thunström, Karin Manhem, T. Yucel-Lindberg, Annika Rosengren, C. Lindberg, Yüksel Peker
Annals of the American Thoracic Society - 2016 -
Prevalence of treatment-resistant hypertension and important associated factors—results from the Swedish Primary Care Cardiovascular
Database
Lina Holmqvist, Kristina Bengtsson Boström, Thomas Kahan, Linus Schiöler, Jan Hasselström, Per Hjerpe, Björn Wettermark, Karin Manhem
Journal of the American Society of Hypertension - 2016 -
Cardiovascular response to stress and perceived stress is not altered 40 years after hypertensive
pregnancies
Anna-Clara Collen, Helena Gustafsson, Margareta Hellgren, Linus Schiöler, Louise Bexander, Karin Manhem
Hypertension in Pregnancy - 2015 -
7b.10: Thiazide Diuretics and Fracture-Risk among Hypertensive Patients. Results from the Swedish Primary Care Cardiovascular Database
(Spccd)
Tove Bokrantz, Charlotta Ljungman, T. Kahan, Linus Schiöler, P. Hjerpe, J. Hasselstrom, B. Wettermark, K. Bostrom, Karin Manhem
Journal of hypertension - 2015 -
7b.02: The Association between Non-Steroidal Anti-Inflammatory Drugs and Blood Pressure Control in Hypertensive Patients and the Relation to
Gender
Charlotta Ljungman, T. Kahan, Linus Schiöler, B. Wettermark, K. B. Bostrom, J. Hasselstrom, Karin Manhem
Journal of hypertension - 2015 -
Epidemiology and standard risk factors in relation to psychosocial risk factors for coronary heart
disease
Annika Rosengren, Karin Manhem
Psychosocial Stress and Cardiovascular Disease in Women: Concepts, Findings, Future Perspectives - 2015 -
Quiz page June 2015: a young woman with
hypertension.
Svante Jansson, Johan Fredén Lindqvist, Karin Manhem, Ola Nilsson, Thord Rosén, Hans Herlitz
American journal of kidney diseases : the official journal of the National Kidney Foundation - 2015 -
Cardiac structure and function is related to current blood pressure rather than to previous hypertensive
pregnancy
Anna-Clara Collen, Magnus C Johansson, Cecilia Wallentin Guron, Helena Gustafsson, Karin Manhem
Journal of Human Hypertension - 2015 -
Antihypertensive treatment and control according to gender, education, country of birth and psychiatric disorder: the Swedish Primary Care Cardiovascular Database
(SPCCD)
Charlotta Ljungman, T. Kahan, Linus Schiöler, P. Hjerpe, B. Wettermark, K. B. Bostrom, Karin Manhem
Journal of Human Hypertension - 2015 -
Effect of catheter-based renal sympathetic denervation on 24-h ambulatory blood pressure in patients with resistant
hypertension.
Sebastian Völz, Bert Andersson, Karin Manhem, Inger Haraldsson, Bengt Rundqvist
Blood pressure - 2014 -
The Swedish Primary Care Cardiovascular Database (SPCCD): 74 751 hypertensive primary care
patients
J. Hasselstrom, R. Zarrinkoub, C. Holmquist, P. Hjerpe, Charlotta Ljungman, M. Qvarnstrom, B. Wettermark, Karin Manhem, T. Kahan, Kristina Bengtsson Boström
Blood Pressure - 2014 -
The role of prestroke glycemic control on severity and outcome of acute ischemic
stroke.
Clara Hjalmarsson, Karin Manhem, Lena Bokemark, Björn Andersson
Stroke Research and Treatment - 2014 -
Gender differences in antihypertensive drug treatment: results from the Swedish Primary Care Cardiovascular Database
(SPCCD).
Charlotta Ljungman, Thomas Kahan, Linus Schiöler, Per Hjerpe, Jan Hasselström, Björn Wettermark, Kristina Bengtsson Boström, Karin Manhem
Journal of the American Society of Hypertension : JASH - 2014 -
[Catheter-based renal denervation: a new method for resistant hypertension. Initial experiences of the procedure shows significant decrease in blood
pressure]
Bengt Rundqvist, S. Volz, Karin Manhem, Hans Herlitz, Inger Haraldsson, B. Andersson
Läkartidningen - 2013 -
Cardiovascular and metabolic characteristics 40 years after hypertensive pregnancies: a long-term follow-up study of
mothers.
Anna-Clara Collen, Margareta Hellgren, Helena Gustafsson, Magnus C Johansson, Karin Manhem
Journal of hypertension - 2013 -
Electrocardiographic Abnormalities and Elevated cTNT at Admission for Intracerebral Hemorrhage: Predictors for
Survival?
Clara Hjalmarsson, Lennart Bergfeldt, Lena Bokemark, Karin Manhem, Björn Andersson
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc - 2013 -
Gender differences in the prevalence of metabolic syndrome in 50-year-old Swedish men and women with hypertension born in
1953
Masuma Novak, Lena Björck, Lennart Welin, Catharina Welin, Karin Manhem, Annika Rosengren
Journal of human hypertension - 2013 -
Persistence to antihypertensive drug treatment in Swedish primary
healthcare
M. Qvarnstrom, T. Kahan, H. Kieler, L. Brandt, J. Hasselstrom, K. B. Bostrom, Karin Manhem, P. Hjerpe, B. Wettermark
European Journal of Clinical Pharmacology - 2013 -
Antihypertensive effect of low-frequency transcutaneous electrical nerve stimulation (TENS) in comparison with drug
treatment
Jonas Silverdal, Georgios Mourtzinis, Elisabet Stener-Victorin, Clas Mannheimer, Karin Manhem
Blood pressure - 2012 -
Exercise blood pressure and the risk of future
hypertension
Lina Holmqvist, Lena Mortensen, C. Kanckos, Charlotta Ljungman, Kirsten Mehlig, Karin Manhem
Journal of human hypertension - 2012 -
The effect of statins on acute and long-term outcome after ischemic stroke in the
elderly.
Clara Hjalmarsson, Lena Bokemark, Karin Manhem, Kirsten Mehlig, Björn Andersson
The American journal of geriatric pharmacotherapy - 2012 -
Sympathetic nerve activity in women 40 years after a hypertensive
pregnancy
Anna-Clara Collen, Karin Manhem, Yrsa Bergmann Sverrisdóttir
Journal of hypertension - 2012 -
[The medical education in Gothenburg is being reformed. Professional development, research and
internationalization]
Eric Hanse, Mats Wahlqvist, A. Sturm, Catharina Lindholm, Börje Haraldsson, R. Andersson, Karin Manhem
Läkartidningen - 2011 -
Antihypertensive treatment and control in a large primary care population of 21 167
patients
M. Qvarnström, B. Wettermark, Charlotta Ljungman, R. Zarrinkoub, J. Hasselström, Karin Manhem, A. Sundström, T. Kahan
Journal of Human Hypertension - 2011 -
Swedish hypertension open care retrospective study in men and women
(SHOW)
Charlotta Ljungman, Anna-Clara Collen, Karin Manhem
Journal of Human Hypertension - 2011 -
Professionell utveckling i läkarutbildningen i Göteborg. Kartläggning och förslag till handlingsplan. Sahlgrenska akademin, juni
2010.
Mats Wahlqvist, Mattias Bjarnegård, Marianne Hall- Angerås, Kerstin Leander, Karin Manhem, Ola Nilsson, Katharina Stibrant Sunnerhagen
2010 -
Twenty-year trends in incidence and 1-year mortality in Swedish patients hospitalised with non-AMI chest pain. Data from 1987-2006 from the Swedish hospital and death
registries
Annika Janson Fagring, Georg Lappas, Karin I Kjellgren, Catharina Welin, Karin Manhem, Annika Rosengren
Heart - 2010 -
Influence of chronic hormone replacement therapy on left ventricular mass and serum-ACE
activity.
Karin Manhem, Bachar Ghanoum, Magnus C Johansson, Ian Milsom, Helena Gustafsson
Blood pressure - 2010 -
Effects of estrogen plus progesterone on hemodynamic and vascular reactivity in hypertensive postmenopausal
women.
Lisa Brandin, Helena Gustafsson, Bachar Ghanoum, Ian Milsom, Karin Manhem
Blood pressure - 2010 -
Treatment of Mild to Moderate Hypertension by Gender Perspective: A Systematic
Review
Charlotta Ljungman, Lena Mortensen, Thomas Kahan, Karin Manhem
JOURNAL OF WOMENS HEALTH - 2009 -
Central sympatholytic therapy has anti-inflammatory properties in hypertensive postmenopausal
women
M. K. Poyhonen-Alho, Karin Manhem, P. Katzman, A. Kibarskis, R. L. Antikainen, R. U. Erkkola, J. O. Tuomilehto, P. E. Ebeling, R. J. Kaaja
Journal of Hypertension - 2008 -
Effects of losartan in women with hypertension and left ventricular hypertrophy: results from the Losartan Intervention for Endpoint Reduction in Hypertension
Study
I. Os, V. Franco, S. E. Kjeldsen, Karin Manhem, R. B. Devereux, E. Gerdts, D. A. Hille, P. A. Lyle, P. M. Okin, Björn Dahlöf, S. Oparil
Hypertension - 2008 -
NT-proBNP ger träffsäker diagnos i
akutskede
J. Javadzadeh, Anna-Clara Collen, Karin Manhem, Karl Swedberg
Läkartidningen - 2008 -
Depression, anxiety, stress, social interaction and health-related quality of life in men and women with unexplained chest
pain
Annika Janson Fagring, Karin I Kjellgren, Annika Rosengren, Lauren Lissner, Karin Manhem, Catharina Welin
BMC Public Health - 2008 -
Psychosocial profile in men and women with unexplained chest
pain
Margaretha Jerlock, Karin I Kjellgren, Fannie Gaston-Johansson, Lauren Lissner, Karin Manhem, Annika Rosengren, Catharina Welin
J Intern Med - 2008 -
Association of physician's sex with risk factor control in treated hypertensive patients from Swedish primary
healthcare.
Gunilla Journath, Mai-Lis Hellénius, Karin Manhem, Karin I Kjellgren, Peter M Nilsson
Journal of hypertension - 2008 -
Effects of sympatholytic therapy on insulin sensitivity indices in hypertensive postmenopausal
women
R. Kaaja, S. Kujala, Karin Manhem, P. Katzman, A. Kibarskis, R. Antikainen, H. Yliharsila, R. Erkkola, J. Tuomilehto
Int J Clin Pharmacol Ther - 2007 -
The liquorice effect on the RAAS differs between the
genders.
Helga A Sigurjónsdóttir, Magnus Axelson, Gudmundur Johannsson, Karin Manhem, Ernst Nyström, Sven Wallerstedt
Blood pressure - 2006 -
Liquorice in moderate doses does not affect sex steroid hormones of biological importance although the effect differs between the
genders.
Helga A Sigurjónsdóttir, Magnus Axelson, Gudmundur Johannsson, Karin Manhem, Ernst Nyström, Sven Wallerstedt
Hormone research - 2006 -
Treatment of postmenopausal hypertension with moxonidine, a selective imidazoline receptor
agonist
R. Kaaja, Karin Manhem, J. Tuomilehto
Int J Clin Pract Suppl - 2004 -
Acute effects of transdermal 17beta-estradiol on hemostatic variables after 24-hour
treatment.
Helena Hognert, Bachar Ghanoum, Helena Gustafsson, Ian Milsom, Karin Manhem
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 2002