MR in Cancer Research
Kort beskrivning
The use of morphological evaluation alone for tumor therapy response assessment is a suboptimal approach due to the late effect of tumor volume reduction. Functional MR techniques, such as diffusion (DWI/IVIM), perfusion (DCE), and oxygenation sensitive (BOLD) imaging and metabolism (MRS) have shown great potential to access tumor physiology, microenvironment, metabolism, vascularity, and cellularity, and are therefore compelling imaging biomarkers for early changes in tumors after therapeutic interventions.
Our research group focusing on MR in cancer works to develop and implement advanced functional MR techniques for characterization of tumor tissue and to find functional MR markers suitable for early treatment assessment and adaptation. MR measurements are applied both in experimental setups (all above mentioned MR methods) as well as in patient studies (MRS and IVIM).
Group members:
Maria Ljungberg, Assoc. Prof.
Mikael Montelius, PhD
Oscar Jalnefjord, PhD
Lukas Lundholm, PhD student
Louise Rosenqvist, PhD student
Eva-Forssell-Aronsson, Prof.
Funding
- Swedish Cancer Society
- King Gustav V Jubilee Clinic Cancer Research Foundation
- Swedish state under the agreement between the Swedish government and the county councils (the ALF agreement)
- Lions Cancer fund West
- Sahlgrenska University Hospital Research Funds
- Assar Gabrielsson Cancer Research Foundation
- Adlerbertska Research Foundation
- Herbert & Karin Jacobsson Foundation
- The Royal Society of Arts and Sciences in Gothenburg (KVVS)
- The Wilhelm and Martina Lundgren Research Foundation