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- Fernando Gonzalez
Fernando Gonzalez
Doktorand
Sektionen för psykiatri och neurokemi-
Plasma brain-derived tau correlates with cerebral infarct
volume.
Fernando Gonzalez-Ortiz, Lukas Holmegaard, Björn Andersson, Cecilia Brännmark, Christian Blomstrand, Henrik Zetterberg, Katarina Jood, Kaj Blennow, Christina Jern, Tara M Stanne
Journal of internal medicine - 2024 -
Clinical value of novel blood-based tau biomarkers in Creutzfeldt-Jakob
disease.
Giuseppe Mario Bentivenga, Fernando Gonzalez-Ortiz, Simone Baiardi, Bjørn-Eivind Kirsebom, Andrea Mastrangelo, Angela Mammana, Sabina Capellari, Tormod Fladby, Henrik Zetterberg, Kaj Blennow, Piero Parchi
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Plasma phosphorylated-tau217 is increased in Niemann-Pick disease type
C
Fernando Gonzalez-Ortiz, Thomas Karikari, Danielle Taylor-Te Vruchte, Dawn Shepherd, Bjorn-Eivind Kirsebom, Tormod Fladby, Frances Platt, Kaj Blennow
BRAIN COMMUNICATIONS - 2024 -
Neuronal plasma biomarkers in acute ischemic
stroke
Julia K. Gundersen, Fernando Gonzalez-Ortiz, Thomas Karikari, Bjorn-Eivind Kirsebom, Katrin Mertes, Henrik Zetterberg, Hlin Kvartsberg, Ole Morten Ronning, Berglind Gisladottir, Kaj Blennow, Tormod Fladby
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM - 2024 -
Biomarkers of tau phosphorylation state are associated with the clinical course of multiple
sclerosis
Andreja Emersic, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Gregor Brecl Jakob, Alenka Horvat Ledinek, Jörg Hanrieder, Henrik Zetterberg, Uros Rot, Sasa Cucnik, Kaj Blennow
MULTIPLE SCLEROSIS AND RELATED DISORDERS - 2024 -
Plasma Brain-Derived Tau in Prognosis of Large Vessel Occlusion Ischemic
Stroke
Ricardo Varela, Fernando Gonzalez-Ortiz, Alexandre Dias, Nicolo Luca Knuth, Joana Fonte, Beatriz Pinto, Idil Yuksekel, Vasco Abreu, Isabel Silva, Liliana Igreja, Joana Lopes, Jose Silva, Rafael Dias, Joao Pedro Filipe, Maria Joao Malaquias, Ana Moutinho, Denis Gabriel, Ana Aires, Rui Antunes, Jose Pedro Rocha, Rui Felgueiras, Ricardo Almendra, Pedro Castro, Henrik Zetterberg, Rui Magalhaes, Thomas K. Karikari, Manuel Correia, Kaj Blennow, Luis F. Maia
STROKE - 2024 -
Cerebrospinal fluid p-tau181, 217, and 231 in definite Creutzfeldt-Jakob disease with and without concomitant
pathologies
Andreja Emersic, Nicholas J. Ashton, Agathe Vrillon, Juan Lantero Rodriguez, Jernej Mlakar, Milica Gregoric Kramberger, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Maciej Dulewicz, Jörg Hanrieder, Eugeen Vanmechelen, Uros Rot, Henrik Zetterberg, Thomas Karikari, Sasa Cucnik, Kaj Blennow
ALZHEIMERS & DEMENTIA - 2024 -
Plasma brain-derived tau is an amyloid-associated neurodegeneration biomarker in Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Bjørn-Eivind Kirsebom, José Contador, Jordan E Tanley, Per Selnes, Berglind Gísladóttir, Lene Pålhaugen, Mathilde Suhr Hemminghyth, Jonas Jarholm, Ragnhild Skogseth, Geir Bråthen, Gøril Grøndtvedt, Atle Bjørnerud, Sandra Tecelao, Knut Waterloo, Dag Aarsland, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Michael Turton, Agnes Hesthamar, Przemyslaw R. Kac, Johanna Nilsson, Jose Luchsinger, Kathleen M Hayden, Peter Harrison, Albert Puig-Pijoan, Henrik Zetterberg, Timothy M Hughes, Marc Suárez-Calvet, Thomas Karikari, Tormod Fladby, Kaj Blennow
Nature communications - 2024 -
Association of Plasma Brain-Derived Tau With Functional Outcome After Ischemic
Stroke.
Tara M Stanne, Fernando Gonzalez-Ortiz, Cecilia Brännmark, Katarina Jood, Thomas Karikari, Kaj Blennow, Christina Jern
Neurology - 2024 -
Plasma p-tau212 antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay R Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Tammaryn Lashley, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
Nature communications - 2024 -
Analytical and clinical validation of Alzheimer's disease blood biomarkers with a focus on plasma
p-tau217.
Fernando Gonzalez-Ortiz, Thomas Karikari, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Levels of plasma brain-derived tau and p-tau181 in Alzheimer's disease and rapidly progressive
dementias.
Fernando Gonzalez-Ortiz, Thomas Karikari, Giuseppe Mario Bentivenga, Simone Baiardi, Angela Mammana, Michael Turton, Przemyslaw R. Kac, Andrea Mastrangelo, Peter Harrison, Sabina Capellari, Henrik Zetterberg, Kaj Blennow, Piero Parchi
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
A novel ultrasensitive assay for plasma p-tau217: Performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand González-Escalante, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Minguillon, Jose Contador, Marc Suárez-Calvet, Thomas Karikari, Kaj Blennow
Alzheimer's & dementia : the journal of the Alzheimer's Association - 2024 -
Longitudinal blood biomarker trajectories in preclinical Alzheimer's
disease
Y. Yakoub, Nicholas J. Ashton, C. Strikwerda-Brown, Laia Montoliu-Gaya, Thomas Karikari, Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, J. Gallego-Rudolf, P. F. Meyer, F. St-Onge, Michael Schöll, J. P. Soucy, J. C. S. Breitner, Henrik Zetterberg, Kaj Blennow, J. Poirier, S. Villeneuve
Alzheimers & Dementia - 2023 -
Preanalytical stability of plasma/serum brain-derived
tau
Fernando Gonzalez-Ortiz, A. Dias, M. Turton, R. Magalhaes, Przemyslaw R. Kac, M. Correia, P. Harrison, Henrik Zetterberg, L. F. Maia, Kaj Blennow, Thomas Karikari
Alzheimers & Dementia - 2023 -
A novel ultrasensitive assay for plasma p-tau217: performance in individuals with subjective cognitive decline and early Alzheimer's
disease.
Fernando Gonzalez-Ortiz, Pamela C L Ferreira, Armand Gonzalez, Laia Montoliu-Gaya, Paula Ortiz-Romero, Przemyslaw R. Kac, Michael Turton, Hlin Kvartsberg, Nicholas J. Ashton, Henrik Zetterberg, Peter Harrison, Bruna Bellaver, Guilherme Povala, Victor L Villemagne, Tharick A Pascoal, Mary Ganguli, Anne D Cohen, Carolina Miguillon, Jose Contador, Marc Suarez-Calvet, Thomas Karikari, Kaj Blennow
medRxiv : the preprint server for health sciences - 2023 -
Plasma and CSF biomarkers in a memory clinic: Head-to-head comparison of phosphorylated tau
immunoassays
Nicholas J. Ashton, A. Puig-Pijoan, M. Mila-Aloma, A. Fernandez-Lebrero, G. Garcia-Escobar, Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner Scheeren Brum, Andréa Lessa Benedet, Juan Lantero Rodriguez, T. A. Day, J. Vanbrabant, E. Stoops, E. Vanmechelen, G. Triana-Baltzer, S. Moughadam, H. Kolb, P. Ortiz-Romero, Thomas Karikari, C. Minguillon, J. J. H. Sanchez, I. Navalpotro-Gomez, O. Grau-Rivera, R. M. Manero, V. Puente-Periz, R. de la Torre, J. Roquer, J. L. Dage, Henrik Zetterberg, Kaj Blennow, M. Suarez-Calvet
Alzheimers & Dementia - 2023 -
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer's
disease.
Kaja Nordengen, Bjørn-Eivind Kirsebom, Grit Richter, Lene Pålhaugen, Berglind Gísladóttir, Nikias Siafarikas, Arne Nakling, Arvid Rongve, Geir Bråthen, Gøril Rolfseng Grøntvedt, Fernando Gonzalez-Ortiz, Knut Waterloo, Kulbhushan Sharma, Thomas Karikari, Eleonora M Vromen, Betty M Tijms, Pieter J Visser, Per Selnes, Milicia G Kramberger, Bengt Winblad, Kaj Blennow, Tormod Fladby
Journal of neuroinflammation - 2023 -
Association of Serum Brain-Derived Tau With Clinical Outcome and Longitudinal Change in Patients With Severe Traumatic Brain
Injury.
Fernando Gonzalez-Ortiz, Maciej Dulewicz, Nicholas J. Ashton, Przemyslaw R. Kac, Henrik Zetterberg, Emma Andersson, Yara Yakoub, Jörg Hanrieder, Michael Turton, Peter Harrison, Bengt Nellgård, Thomas Karikari, Kaj Blennow
JAMA network open - 2023 -
Plasma p-tau212: antemortem diagnostic performance and prediction of autopsy verification of Alzheimer's disease
neuropathology.
Przemyslaw R. Kac, Fernándo González-Ortiz, Andreja Emeršič, Maciej Dulewicz, Srinivas Koutarapu, Michael Turton, Yang An, Denis Smirnov, Agnieszka Kulczyńska-Przybik, Vijay Varma, Nicholas J. Ashton, Laia Montoliu-Gaya, Elena Camporesi, Izabela Winkel, Bogusław Paradowski, Abhay Moghekar, Juan C Troncoso, Gunnar Brinkmalm, Susan M Resnick, Barbara Mroczko, Hlin Kvartsberg, Milica Gregorič Kramberger, Jörg Hanrieder, Saša Čučnik, Peter Harrison, Henrik Zetterberg, Piotr Lewczuk, Madhav Thambisetty, Uroš Rot, Douglas Galasko, Kaj Blennow, Thomas Karikari
medRxiv : the preprint server for health sciences - 2023 -
alfa-Synuclein seed amplification assay as a diagnostic tool for parkinsonian
disorders
Fernando Gonzalez-Ortiz, Bengt Nellgård
Parkinsonism & Related Disorders - 2023 -
Brain-derived Tau for Monitoring Brain Injury in Acute Ischemic
Stroke.
Naomi Vlegels, Fernando Gonzalez-Ortiz, Nicoló Luca Knuth, Nada Khalifeh, Benno Gesierich, Franziska Müller, Philipp Müller, Matthias Klein, Konstantinos Dimitriadis, Nicolai Franzmeier, Thomas Liebig, Marco Duering, Paul Reidler, Martin Dichgans, Thomas Karikari, Kaj Blennow, Steffen Tiedt
medRxiv : the preprint server for health sciences - 2023 -
Plasma and cerebrospinal fluid glial fibrillary acidic protein levels in adults with Down syndrome: a longitudinal cohort
study
Laia Montoliu-Gaya, D. Alcolea, Nicholas J. Ashton, J. Pegueroles, J. Levin, B. Bosch, Juan Lantero Rodriguez, M. Carmona-Iragui, O. Wagemann, M. Balasa, Przemyslaw R. Kac, I. Barroeta, A. Llado, Wagner Scheeren Brum, L. Videla, Fernando Gonzalez-Ortiz, B. Benejam, J. J. A. Martinez, Thomas Karikari, G. Nubling, A. Bejanin, Andréa Lessa Benedet, R. Blesa, A. Lleo, Kaj Blennow, R. Sanchez-Valle, Henrik Zetterberg, J. Fortea
eBioMedicine - 2023 -
Plasma phospho-tau in Alzheimer's disease: towards diagnostic and therapeutic trial
applications
Fernando Gonzalez-Ortiz, Przemyslaw R. Kac, Wagner Scheeren Brum, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Molecular Neurodegeneration - 2023 -
Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease
monitoring.
Nicholas J. Ashton, Shorena Janelidze, Niklas Mattsson-Carlgren, Alexa Pichet Binette, Olof Strandberg, Wagner Scheeren Brum, Thomas Karikari, Fernándo González-Ortiz, Guglielmo Di Molfetta, Francisco J Meda, Erin M Jonaitis, Rebecca Langhough Koscik, Karly Cody, Tobey J Betthauser, Yan Li, Eugeen Vanmechelen, Sebastian Palmqvist, Erik Stomrud, Randall J Bateman, Henrik Zetterberg, Sterling C Johnson, Kaj Blennow, Oskar Hansson
Nature medicine - 2022 -
Brain-derived tau: a novel blood-based biomarker for Alzheimer's disease-type
neurodegeneration.
Fernando Gonzalez-Ortiz, Michael Turton, Przemyslaw R. Kac, Denis Smirnov, Enrico Premi, Roberta Ghidoni, Luisa Benussi, Valentina Cantoni, Claudia Saraceno, Jasmine Rivolta, Nicholas J. Ashton, Barbara Borroni, Douglas Galasko, Peter Harrison, Henrik Zetterberg, Kaj Blennow, Thomas Karikari
Brain : a journal of neurology - 2022 -
Diagnostic value of serum versus plasma phospho-tau for Alzheimer's
disease
Przemyslaw R. Kac, Fernando Gonzalez-Ortiz, Joel Simrén, N. Dewit, E. Vanmechelen, Henrik Zetterberg, Kaj Blennow, Nicholas J. Ashton, Thomas Karikari
Alzheimer's Research & Therapy - 2022