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Lars Frisén
Om Lars Frisén
Utbildning: med lic och leg läk 1966, med dr 1968, post-doctoral fellow in neuro-ophthalmology vid University of California, San Francisco 1972-1973, specialist i ögonsjukdomar 1974.
Kompetenser: docent i anatomi 1968, docent i experimentell oftalmologi 1971, docent i klinisk neuro-oftalmologi 1973, adjungerad professor 2000.
Pensionsavgång 2006.
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Klinisk neuro-oftalmologi är en primärt diagnostisk disciplin som använder oftalmologiska tekniker för analys av störningar i centrala nervsystemet. Öga och nervsystem har täta kopplingar. Hjärnan analyserar nervsignalerna från ögats synceller på en mängd komplexa sätt och hjärnan styr komplexa ögonfunktioner såsom ögonrörelser och pupiller. Sjukdomar i nervsystemet manifesteras ofta som syn- och ögonrörelsestörningar samt förändringar i ögats inre (ögonbotten). Analys av sådana störningar är viktiga steg i kliniska utredningar. En rikt illustrerad översikt av neuro-oftalmologins panorama finns på forskargruppens webbplats, www.neuro-o.se/Index.html Forskargruppen har utvecklat många diagnostiska metoder som funnit vid användning internationellt, t.ex. High-pass Resolution Perimetry, Sahlgren’s Color Saturation Test och Disc Swelling Staging Scheme.
På senare år har metodutvecklingen fokuserat på smartphone-appar. De senaste är: MultiBit Vision Test - självmonitorering vid åldersrelaterad makuladegeneration VisionSx - interaktiv visuell katalog över vanliga synstörningar avsedd att underlätta den ofta svåra diagnostiken LookAhead - interaktivt spel avsett för träning av kompensation för homonym hemianopsi
-
Swelling of the Optic Nerve Head: A Backstage View of a Staging
Scheme.
Lars Frisén
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society - 2017 -
Dichoptic Reaction Times Open a New Window on Functional Loss of
Vision
Lars Frisén
Ophthalmology - 2016 -
New rarebit vision test captures macular deficits hidden to acuity
tests
Christina Winther, Lars Frisén
Acta Ophthalmologica - 2015 -
Self-Testing of Vision in Age-Related Macula Degeneration: A Longitudinal Pilot Study Using a Smartphone-Based Rarebit
Test
Christina Winther, Lars Frisén
Journal of Ophthalmology - 2015 -
Identification of functional visual field loss by automated static
perimetry
Lars Frisén
Acta Ophthalmologica - 2014 -
Rapid Assessment of Neurovisual Integrity Using Multiple
Rarebits
Lars Frisén
Ophthalmology - 2013 -
Performance of a Rapid Rarebit Central-Vision Test with Optic
Neuropathies
Lars Frisén
Optometry and Vision Science - 2012 -
Ocular torsions and the subjective visual vertical with central vestibulo-ocular system lesions: independence
disproved
Lars Frisén
Acta Neurologica Scandinavica - 2012 -
Optical coherence tomography for optic disc edema -
Reply
Kardon RH, CJ Scott, AG Lee, Lars Frisén, Wall
Archives of Ophthalmology - 2011 -
Postural function and subjective eye level in patients with idiopathic normal pressure
hydrocephalus.
Elisabeth Blomsterwall, Lars Frisén, Carsten Wikkelsö
Journal of neurology - 2011 -
Deviations of the visual upright in three dimensions in disorders of the brainstem: a clinical
exploration.
Lars Frisén
Brain : a journal of neurology - 2010 -
Diagnosis and Grading of Papilledema in Patients with Raised Intracranial Pressure Using Optical Coherence Tomography vs Clinical Expert Assessment using a Clinical Staging
Scale
CJ Scott, RH Kardon, AG Lee, Lars Frisén, M Wall
Archives of ophthalmology - 2010 -
Scope of super-resolution in central
vision.
Lars Frisén
The British journal of ophthalmology - 2010 -
A compact rarebit test for macular
diseases.
Christina Winther, Lars Frisén
The British journal of ophthalmology - 2010 -
Device and method for a vision
test
Lars Frisén
2009 -
The Amsler grid in modern
clothes.
Lars Frisén
The British journal of ophthalmology - 2009 -
Evolution of drusen of the optic nerve head over 23 years. Report of a
case
Lars Frisén
Acta Ophthalmologica - 2008 -
How robust is the optic chiasm? Perimetric and neuro-imaging
correlations
Lars Frisén, Christer Jensen
Acta Neurologica Scandinavica - 2008 -
Anisotropic enhancement of the retinal nerve fiber
layer.
Lars Frisén
Neuro-Ophtalmology - 2007 -
The lazy shadow: a monocular counterpart to the Pulfrich stereo
phenomenon.
Lars Frisén
The British journal of ophthalmology - 2007 -
Influence of ageing on visual field defects due to stable
lesions.
Thiemo Rudolph, Lars Frisén
The British journal of ophthalmology - 2007 -
Rarebit
perimetrisi
Lars Frisén
Görme Alani El Kitabi - 2005 -
Visual field of high-pass resolution perimetry in normal
subjects.
Michael Wall, Balwantray Chauhan, Lars Frisén, Philip H House, Caridad Brito
Journal of glaucoma - 2004 -
Visual field defects after temporal lobectomy -- comparing methods and analysing resection
size
Daniel Nilsson, Kristina Malmgren, Bertil Rydenhag, Lars Frisén
Acta Neurol Scand - 2004 -
Vigabatrin-associated loss of vision: rarebit perimetry illuminates the dose-damage
relationship
Lars Frisén
Acta Ophthalmologica Scandinavica - 2004 -
Characterization of vigabatrin-associated optic
atrophy.
Lars Frisén, Kristina Malmgren
Acta ophthalmologica Scandinavica - 2003 -
Internal carotid artery aneurysms, cranial nerve dysfunction and headache: the role of deformation and
pulsation.
M Rodríguez-Catarino, Lars Frisén, G Wikholm, J Elfverson, L Quiding, P Svendsen
Neuroradiology - 2003 -
Subjective visual vertical and Romberg's test correlations in
hydrocephalus.
Carsten Wikkelsö, Elisabeth Blomsterwall, Lars Frisén
Journal of neurology - 2003 -
Multiple sclerosis siblings with cerebrospinal fluid immunopathy but without any indication of neuronal
damage.
S Haghighi, Lars Frisén, A Odén, O Andersen
Acta neurologica Scandinavica - 2003 -
Intra-individual relations between resolution and retinal ganglion cell
numbers
Johan Sjöstrand, Zoran Popovic, Lars Frisén
Investigative Ophthalmology & Visual Science - 2003 -
New, sensitive window on abnormal spatial vision: rarebit
probing.
Lars Frisén
Vision research - 2002 -
Asymptomatic visual loss in multiple
sclerosis.
Jan Lycke, Per Olof Tollesson, Lars Frisén
Journal of neurology - 2001 -
Vigabatrin visual toxicity: evolution and dose
dependence.
K Malmgren, E Ben-Menachem, Lars Frisén
Epilepsia - 2001 -
Direct puncture and sclerotherapy with sotradecol ((r)) . Orbital lymphatic
malformations.
P A Svendsen, G Wikholm, M Rodriguez, P Enoksson, Lars Frisén, K Strömland, S Seregard
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences - 2001 -
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on
Treatment.
M Lindberger, M Alenius, Lars Frisén, S I Johannessen, S Larsson, K Malmgren, T Tomson
Epilepsia - 2000 -
Surgically created fourth-third cranial nerve communication: temporary success in a child with bilateral third nerve hamartomas. Case
report.
Lars Frisén, C von Essen, A Roos
Journal of neurosurgery - 1999 -
Acyclovir treatment of relapsing-remitting multiple sclerosis. A randomized, placebo-controlled, double-blind
study.
Jan Lycke, Bo Svennerholm, Elisabeth Hjelmquist, Lars Frisén, Gaby Badr, Mats Andersson, A Vahlne, Oluf Andersen
Journal of neurology - 1996 -
Relative dispersion analysis enhances perimetric
sensitivity.
Lars Frisén, S Rossitti
Vision research - 1996 -
High-pass resolution perimetry: central-field neuroretinal
correlates.
Lars Frisén
Vision research - 1995 -
[Vasospastic amaurosis fugax. Is there such an
animal?].
Lars Frisén
Lakartidningen - 1994 -
Remodelling of the retinal arterioles in descending optic atrophy follows the principle of minimum
work.
S Rossitti, Lars Frisén
Acta physiologica Scandinavica - 1994 -
High-pass resolution perimetry. A clinical
review.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1993 -
Properties of high-pass resolution perimetry
targets.
Lars Frisén, F Nikolajeff
Acta ophthalmologica - 1993 -
[Craniotomy is not necessary. Embolization with detachable balloons is the most suitable treatment of direct carotid-cavernous
fistulas].
P Svendsen, G Wikholm, J Löfgren, Lars Frisén
Lakartidningen - 1992 -
High-pass resolution perimetry and age-related loss of visual pathway
neurons.
Lars Frisén
Acta ophthalmologica - 1991 -
A primer of ophthalmic computer
graphics.
Lars Frisén, B Lindblom
Documenta ophthalmologica. Advances in ophthalmology - 1990 -
Decompression of the orbit using a lateral rhinotomy approach in patients with malignant endocrine
exophthalmos.
B Petruson, Lars Frisén
Clinical otolaryngology and allied sciences - 1990 -
Sahlgren's Saturation Test for acquired dyschromatopsia: increased lightness enhances
sensitivity.
B Lindblom, M Wikholm, Lars Frisén
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1988 -
Acuity perimetry: estimation of neural
channels.
Lars Frisén
International ophthalmology - 1988 -
Computerized perimetry: possibilities for individual adaptation and
feedback.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1988 -
Binocular summation in humans: evidence for a hierarchic
model.
Lars Frisén, B Lindblom
The Journal of physiology - 1988 -
Perimetric variability: importance of criterion
level.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1988 -
Clinical observations of effects on central nervous system in patients with acute facial
palsy.
P Hanner, O Andersen, Lars Frisén, U Rosenhall, S Edström
Archives of otolaryngology--head & neck surgery - 1987 -
High-pass resolution targets in peripheral
vision.
Lars Frisén
Ophthalmology - 1987 -
Posttraumatic seesaw nystagmus abolished by ethanol
ingestion.
Lars Frisén, C Wikkelsø
Neurology - 1986 -
Vanishing optotypes. New type of acuity test
letters.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1986 -
The cerebral ocular pursuit pathways. A clinicoradiological study of small-field optokinetic
nystagmus.
L Kjällman, Lars Frisén
Journal of clinical neuro-ophthalmology - 1986 -
Visual acuity in optic atrophy: a quantitative clinicopathological
analysis.
Lars Frisén, H A Quigley
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1984 -
Episodic astigmatism heralding generalized myopathy: report of a case managed with a new type of soft contact
lens.
Lars Frisén, C Blomstrand
Ophthalmology - 1984 -
Narrowing of the retinal arterioles in descending optic atrophy. A quantitative clinical
study.
Lars Frisén, M Claesson
Ophthalmology - 1984 -
Funduscopic and functional correlates of demyelinating optic
neuropathy.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Fundus changes in acute malnutritional optic
neuropathy.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1983 -
Clinical features of optic neuritis standard examination
techniques.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Demyelinating optic neuropathy. Notes on clinical examination
techniques.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Swelling of the optic nerve head: a staging
scheme.
Lars Frisén
Journal of neurology, neurosurgery, and psychiatry - 1982 -
How good is normal visual acuity?. A study of letter acuity thresholds as a function of
age.
Lars Frisén, M Frisén
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology - 1981 -
[Pupillary disorders. A chart for their differential
diagnosis].
Lars Frisén
Lakartidningen - 1981 -
[Nystagmus guide. A system for differential
diagnosis].
Lars Frisén
Lakartidningen - 1981 -
Sahlgren's saturation test for detecting and grading acquired
dyschromatopsia.
Lars Frisén, H Kalm
American journal of ophthalmology - 1981 -
The neurology of visual
acuity.
Lars Frisén
Brain : a journal of neurology - 1980 -
Photography of the retinal nerve fibre layer: an optimised
procedure.
Lars Frisén
The British journal of ophthalmology - 1980 -
Micropsia and visual acuity in macular edema. A study of the neuro-retinal basis of visual
acuity.
Lars Frisén, M Frisén
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology - 1979 -
Detection of extracranial carotid stenosis by computed
tomography.
Lars Frisén, L Kjällman, B Lindberg, P Svendsen
Lancet (London, England) - 1979 -
Quadruple sectoranopia and sectorial optic atrophy: a syndrome of the distal anterior choroidal
artery.
Lars Frisén
Journal of neurology, neurosurgery, and psychiatry - 1979 -
Spectrum of optic nerve
hypoplasia.
Lars Frisén, L Holmegaard
The British journal of ophthalmology - 1978 -
Communicating exophthalmos: a sign of bilateral orbital roof
defects.
Lars Frisén, J Löfgren
Acta neurochirurgica - 1978 -
Sectorial optic atrophy and homonymous, horizontal sectoranopia: a lateral choroidal artery
syndrome?
Lars Frisén, L Holmegaard, M Rosencrantz
Journal of neurology, neurosurgery, and psychiatry - 1978 -
Lateropulsion of the eyes--a localizing brainstem
sign.
Lars Frisén
Journal of neurology - 1978 -
Drusen in the optic nerve head. Verification by computerized
tomography.
Lars Frisén, G Schöldström, P Svendsen
Archives of ophthalmology (Chicago, Ill. : 1960) - 1978 -
Computed frontal tomography (CFT) of the orbit using the EMI CT 1010 head
scanner.
Lars Frisén, L Kjällman, P Svendsen
Neuroradiology - 1978 -
Relationship between perimetric eccentricity and retinal locus in a human eye. Comparison with theoretical
calculations.
Lars Frisén, G Schöldström
Acta ophthalmologica - 1977 -
Atrophy of optic nerve fibres in compression of the chiasm. Prognostic
implications.
M Lundström, Lars Frisén
Acta ophthalmologica - 1977 -
Contrast sensitivity in macular disease. A preliminary
report.
J Sjöstrand, Lars Frisén
Acta ophthalmologica - 1977 -
Sarcoid-like disorder of the intracranial optic
nerve.
Lars Frisén, S Lindgren, B J MacGregor, S Stattin
Journal of neurology, neurosurgery, and psychiatry - 1977 -
[The aqueduct
syndrome].
Lars Frisén
Lakartidningen - 1977 -
A simple relationship between the probability distribution of visual acuity and the density of retinal output
channels.
Lars Frisén, M Frisén
Acta ophthalmologica - 1976 -
Atrophy of optic nerve fibres in compression of the chiasm. Degree and distribution of ophthalmoscopic
changes.
M Lundström, Lars Frisén
Acta ophthalmologica - 1976 -
Cyclic compression of the intracranial optic nerve: patterns of visual failure and
recovery.
Lars Frisén, J Sjöstrand, K Norrsell, S Lindgren
Journal of neurology, neurosurgery, and psychiatry - 1976 -
Objective recognition of abnormal
isopters.
Lars Frisén, M Frisén
Acta ophthalmologica - 1975 -
Optical and neural resolution in peripheral
vision.
Lars Frisén, A Glansholm
Investigative ophthalmology - 1975 -
Evolution of descending optic atrophy. A case
report.
M Lundström, Lars Frisén
Acta ophthalmologica - 1975 -
An ideal test object for the tangent
screen.
Lars Frisén
Acta ophthalmologica - 1974 -
[Amaurosis fugax--differential diagnosis and
treatment].
Lars Frisén
Lakartidningen - 1974 -
Insidious atrophy of retinal nerve fibers in multiple sclerosis. Funduscopic identification in patients with and without visual
complaints.
Lars Frisén, W F Hoyt
Archives of ophthalmology (Chicago, Ill. : 1960) - 1974 -
Unsharp masking in fundus
photography.
Lars Frisén, W F Hoyt
Investigative ophthalmology - 1973 -
Optociliary veins, disc pallor and visual loss. A triad of signs indicating spheno-orbital
meningioma.
Lars Frisén, W F Royt, B M Tengroth
Acta ophthalmologica - 1973 -
A versatile color confrontation test for the central visual field. A comparison with quantitative
perimetry.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1973 -
[Optokinetic nystagmus in neurological focal
diagnosis].
Lars Frisén
Lakartidningen - 1973 -
Diagnostic uses of the Pulfrich
phenomenon.
Lars Frisén, W F Hoyt, A C Bird, R A Weale
Lancet (London, England) - 1973 -
Fundoscopy of nerve fiber layer defects in
glaucoma.
Lars Frisén, N M Newman
Investigative ophthalmology - 1973 -
Resolution at low contrast with a fundus camera. Comparison of various photographic
films.
Lars Frisén
Investigative ophthalmology - 1973 -
An adjustable biomicroscopy contact glass with erect
imagery.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1972 -
Illumination box for colour vision
tests.
Lars Frisén, A Hedin
Acta ophthalmologica - 1972 -
Forced motion attachment for the Goldmann
perimeter.
Lars Frisén
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde - 1972 -
Genuine, relative binasal hemianopia. Report of a
case.
Lars Frisén
Acta ophthalmologica - 1971 -
The cartographic deformations of the visual
field.
Lars Frisén
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde - 1970 -
On objective analysis in kinetic
perimetry.
Lars Frisén
Acta ophthalmologica - 1970 -
Integral arc illumination for projection
perimeters.
Lars Frisén
Acta ophthalmologica - 1969 -
Effects of hypophysectomy and thyroxine on volume and biochemistry of orbital tissue in the crucian carp (Carassius carassius
L.).
Lars Frisén, G Prame
Experimental eye research - 1968 -
Simultaneous bioassay of exophthalmos-producing and thyrotrophic substances. I. The EPS
assay.
Lars Frisén
Acta endocrinologica - 1968 -
Simultaneous bioassay of exophthalmos-producing and thyrotrophic substances. II. The TSH
assays.
Lars Frisén
Acta endocrinologica - 1968 -
Critical analysis of exophthalmometry. An experimental evaluation of conventional and extended
method.
Lars Frisén
Acta ophthalmologica - 1967 -
Reliability of intraperitoneal injections in
fish.
Lars Frisén
Experientia - 1967 -
Analysis of the topographic distribution of thyroid activity in a teleost fish: Carassius carassius
L.
Lars Frisén, M Frisén
Acta endocrinologica - 1967 -
Rapid transmandibular hypophysectomy of small
fish.
Lars Frisén
Experientia - 1967 -
On the occurrence and nature of exophthalmogenic substances, especially in human
serum.
Lars Frisén, B Tengroth
Acta ophthalmologica - 1965 -
An improved method for the assay of exophthalmos-producing
substance.
B Tengroth, R Brunish, Lars Frisén
Acta ophthalmologica - 1964 -
A CYTOTOXIC SERUM FACTOR IN HEART DISEASE, ESPECIALLY
MYOCARDITIS.
S BENGMARK, Lars Frisén, E HELANDER
Acta allergologica - 1963