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Lars Frisén
About Lars Frisén
MD 1966, PhD 1968, Post-doctoral Fellow in Neuro-ophthalmology at University of California, San Francisco 1972-1973, Specialist in Ophthalmology 1974.
Docent of Anatomy 1968, Docent of Experimental Ophthalmology 1971, Docent of Clinical Neuro-ophthalmology 1973, Adjunct Professor 2000.
Mandatory retirement 2006.
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Clinical neuro-ophthalmology is a primarily diagnostic discipline that uses ophthalmological methods to analyse disturbances of the central nervous system. The eye and the brain have close connections. The brain analyses neural signals from the eyes in many complex ways and the brain controls many complex eye functions, including eye movements and pupils. Diseases of the central nervous system often manifest themselves as disturbances of vision and eye movements and changes in the fundus of the eyes. Analysis of such disturbances constitute important steps in clinical evaluations. A richly illustrated overview of the neuro-ophthalmological panorama is available at the research group's website, www.neuro-o.se/Index.html
The research group has developed several diagnostic methods that are in wide use internationally, including RareBit Perimetry, Sahlgren’s Color Saturation Test and a Disc Swelling Staging Scheme. Nowadays, development has turned toward smartphone apps, for example:
MultiBit Vision Test - self-monitoring of age-related macula degeneration Vision Sx - an interactive library of visual disturbances aimed to facilitate differential diagnosis LookAhead - an interactive game aimed to train compensation for homonymous hemianopsia
-
Swelling of the Optic Nerve Head: A Backstage View of a Staging
Scheme.
Lars Frisén
Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society - 2017 -
Dichoptic Reaction Times Open a New Window on Functional Loss of
Vision
Lars Frisén
Ophthalmology - 2016 -
New rarebit vision test captures macular deficits hidden to acuity
tests
Christina Winther, Lars Frisén
Acta Ophthalmologica - 2015 -
Self-Testing of Vision in Age-Related Macula Degeneration: A Longitudinal Pilot Study Using a Smartphone-Based Rarebit
Test
Christina Winther, Lars Frisén
Journal of Ophthalmology - 2015 -
Identification of functional visual field loss by automated static
perimetry
Lars Frisén
Acta Ophthalmologica - 2014 -
Rapid Assessment of Neurovisual Integrity Using Multiple
Rarebits
Lars Frisén
Ophthalmology - 2013 -
Performance of a Rapid Rarebit Central-Vision Test with Optic
Neuropathies
Lars Frisén
Optometry and Vision Science - 2012 -
Ocular torsions and the subjective visual vertical with central vestibulo-ocular system lesions: independence
disproved
Lars Frisén
Acta Neurologica Scandinavica - 2012 -
Optical coherence tomography for optic disc edema -
Reply
Kardon RH, CJ Scott, AG Lee, Lars Frisén, Wall
Archives of Ophthalmology - 2011 -
Postural function and subjective eye level in patients with idiopathic normal pressure
hydrocephalus.
Elisabeth Blomsterwall, Lars Frisén, Carsten Wikkelsö
Journal of neurology - 2011 -
Deviations of the visual upright in three dimensions in disorders of the brainstem: a clinical
exploration.
Lars Frisén
Brain : a journal of neurology - 2010 -
Diagnosis and Grading of Papilledema in Patients with Raised Intracranial Pressure Using Optical Coherence Tomography vs Clinical Expert Assessment using a Clinical Staging
Scale
CJ Scott, RH Kardon, AG Lee, Lars Frisén, M Wall
Archives of ophthalmology - 2010 -
Scope of super-resolution in central
vision.
Lars Frisén
The British journal of ophthalmology - 2010 -
A compact rarebit test for macular
diseases.
Christina Winther, Lars Frisén
The British journal of ophthalmology - 2010 -
Device and method for a vision
test
Lars Frisén
2009 -
The Amsler grid in modern
clothes.
Lars Frisén
The British journal of ophthalmology - 2009 -
Evolution of drusen of the optic nerve head over 23 years. Report of a
case
Lars Frisén
Acta Ophthalmologica - 2008 -
How robust is the optic chiasm? Perimetric and neuro-imaging
correlations
Lars Frisén, Christer Jensen
Acta Neurologica Scandinavica - 2008 -
Anisotropic enhancement of the retinal nerve fiber
layer.
Lars Frisén
Neuro-Ophtalmology - 2007 -
The lazy shadow: a monocular counterpart to the Pulfrich stereo
phenomenon.
Lars Frisén
The British journal of ophthalmology - 2007 -
Influence of ageing on visual field defects due to stable
lesions.
Thiemo Rudolph, Lars Frisén
The British journal of ophthalmology - 2007 -
Rarebit
perimetrisi
Lars Frisén
Görme Alani El Kitabi - 2005 -
Visual field of high-pass resolution perimetry in normal
subjects.
Michael Wall, Balwantray Chauhan, Lars Frisén, Philip H House, Caridad Brito
Journal of glaucoma - 2004 -
Visual field defects after temporal lobectomy -- comparing methods and analysing resection
size
Daniel Nilsson, Kristina Malmgren, Bertil Rydenhag, Lars Frisén
Acta Neurol Scand - 2004 -
Vigabatrin-associated loss of vision: rarebit perimetry illuminates the dose-damage
relationship
Lars Frisén
Acta Ophthalmologica Scandinavica - 2004 -
Characterization of vigabatrin-associated optic
atrophy.
Lars Frisén, Kristina Malmgren
Acta ophthalmologica Scandinavica - 2003 -
Internal carotid artery aneurysms, cranial nerve dysfunction and headache: the role of deformation and
pulsation.
M Rodríguez-Catarino, Lars Frisén, G Wikholm, J Elfverson, L Quiding, P Svendsen
Neuroradiology - 2003 -
Subjective visual vertical and Romberg's test correlations in
hydrocephalus.
Carsten Wikkelsö, Elisabeth Blomsterwall, Lars Frisén
Journal of neurology - 2003 -
Multiple sclerosis siblings with cerebrospinal fluid immunopathy but without any indication of neuronal
damage.
S Haghighi, Lars Frisén, A Odén, O Andersen
Acta neurologica Scandinavica - 2003 -
Intra-individual relations between resolution and retinal ganglion cell
numbers
Johan Sjöstrand, Zoran Popovic, Lars Frisén
Investigative Ophthalmology & Visual Science - 2003 -
New, sensitive window on abnormal spatial vision: rarebit
probing.
Lars Frisén
Vision research - 2002 -
Asymptomatic visual loss in multiple
sclerosis.
Jan Lycke, Per Olof Tollesson, Lars Frisén
Journal of neurology - 2001 -
Vigabatrin visual toxicity: evolution and dose
dependence.
K Malmgren, E Ben-Menachem, Lars Frisén
Epilepsia - 2001 -
Direct puncture and sclerotherapy with sotradecol ((r)) . Orbital lymphatic
malformations.
P A Svendsen, G Wikholm, M Rodriguez, P Enoksson, Lars Frisén, K Strömland, S Seregard
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences - 2001 -
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on
Treatment.
M Lindberger, M Alenius, Lars Frisén, S I Johannessen, S Larsson, K Malmgren, T Tomson
Epilepsia - 2000 -
Surgically created fourth-third cranial nerve communication: temporary success in a child with bilateral third nerve hamartomas. Case
report.
Lars Frisén, C von Essen, A Roos
Journal of neurosurgery - 1999 -
Acyclovir treatment of relapsing-remitting multiple sclerosis. A randomized, placebo-controlled, double-blind
study.
Jan Lycke, Bo Svennerholm, Elisabeth Hjelmquist, Lars Frisén, Gaby Badr, Mats Andersson, A Vahlne, Oluf Andersen
Journal of neurology - 1996 -
Relative dispersion analysis enhances perimetric
sensitivity.
Lars Frisén, S Rossitti
Vision research - 1996 -
High-pass resolution perimetry: central-field neuroretinal
correlates.
Lars Frisén
Vision research - 1995 -
[Vasospastic amaurosis fugax. Is there such an
animal?].
Lars Frisén
Lakartidningen - 1994 -
Remodelling of the retinal arterioles in descending optic atrophy follows the principle of minimum
work.
S Rossitti, Lars Frisén
Acta physiologica Scandinavica - 1994 -
High-pass resolution perimetry. A clinical
review.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1993 -
Properties of high-pass resolution perimetry
targets.
Lars Frisén, F Nikolajeff
Acta ophthalmologica - 1993 -
[Craniotomy is not necessary. Embolization with detachable balloons is the most suitable treatment of direct carotid-cavernous
fistulas].
P Svendsen, G Wikholm, J Löfgren, Lars Frisén
Lakartidningen - 1992 -
High-pass resolution perimetry and age-related loss of visual pathway
neurons.
Lars Frisén
Acta ophthalmologica - 1991 -
A primer of ophthalmic computer
graphics.
Lars Frisén, B Lindblom
Documenta ophthalmologica. Advances in ophthalmology - 1990 -
Decompression of the orbit using a lateral rhinotomy approach in patients with malignant endocrine
exophthalmos.
B Petruson, Lars Frisén
Clinical otolaryngology and allied sciences - 1990 -
Sahlgren's Saturation Test for acquired dyschromatopsia: increased lightness enhances
sensitivity.
B Lindblom, M Wikholm, Lars Frisén
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1988 -
Acuity perimetry: estimation of neural
channels.
Lars Frisén
International ophthalmology - 1988 -
Computerized perimetry: possibilities for individual adaptation and
feedback.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1988 -
Binocular summation in humans: evidence for a hierarchic
model.
Lars Frisén, B Lindblom
The Journal of physiology - 1988 -
Perimetric variability: importance of criterion
level.
Lars Frisén
Documenta ophthalmologica. Advances in ophthalmology - 1988 -
Clinical observations of effects on central nervous system in patients with acute facial
palsy.
P Hanner, O Andersen, Lars Frisén, U Rosenhall, S Edström
Archives of otolaryngology--head & neck surgery - 1987 -
High-pass resolution targets in peripheral
vision.
Lars Frisén
Ophthalmology - 1987 -
Posttraumatic seesaw nystagmus abolished by ethanol
ingestion.
Lars Frisén, C Wikkelsø
Neurology - 1986 -
Vanishing optotypes. New type of acuity test
letters.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1986 -
The cerebral ocular pursuit pathways. A clinicoradiological study of small-field optokinetic
nystagmus.
L Kjällman, Lars Frisén
Journal of clinical neuro-ophthalmology - 1986 -
Visual acuity in optic atrophy: a quantitative clinicopathological
analysis.
Lars Frisén, H A Quigley
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1984 -
Episodic astigmatism heralding generalized myopathy: report of a case managed with a new type of soft contact
lens.
Lars Frisén, C Blomstrand
Ophthalmology - 1984 -
Narrowing of the retinal arterioles in descending optic atrophy. A quantitative clinical
study.
Lars Frisén, M Claesson
Ophthalmology - 1984 -
Funduscopic and functional correlates of demyelinating optic
neuropathy.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Fundus changes in acute malnutritional optic
neuropathy.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1983 -
Clinical features of optic neuritis standard examination
techniques.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Demyelinating optic neuropathy. Notes on clinical examination
techniques.
Lars Frisén
Bulletin de la Societe belge d'ophtalmologie - 1983 -
Swelling of the optic nerve head: a staging
scheme.
Lars Frisén
Journal of neurology, neurosurgery, and psychiatry - 1982 -
How good is normal visual acuity?. A study of letter acuity thresholds as a function of
age.
Lars Frisén, M Frisén
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology - 1981 -
[Pupillary disorders. A chart for their differential
diagnosis].
Lars Frisén
Lakartidningen - 1981 -
[Nystagmus guide. A system for differential
diagnosis].
Lars Frisén
Lakartidningen - 1981 -
Sahlgren's saturation test for detecting and grading acquired
dyschromatopsia.
Lars Frisén, H Kalm
American journal of ophthalmology - 1981 -
The neurology of visual
acuity.
Lars Frisén
Brain : a journal of neurology - 1980 -
Photography of the retinal nerve fibre layer: an optimised
procedure.
Lars Frisén
The British journal of ophthalmology - 1980 -
Micropsia and visual acuity in macular edema. A study of the neuro-retinal basis of visual
acuity.
Lars Frisén, M Frisén
Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology - 1979 -
Detection of extracranial carotid stenosis by computed
tomography.
Lars Frisén, L Kjällman, B Lindberg, P Svendsen
Lancet (London, England) - 1979 -
Quadruple sectoranopia and sectorial optic atrophy: a syndrome of the distal anterior choroidal
artery.
Lars Frisén
Journal of neurology, neurosurgery, and psychiatry - 1979 -
Spectrum of optic nerve
hypoplasia.
Lars Frisén, L Holmegaard
The British journal of ophthalmology - 1978 -
Communicating exophthalmos: a sign of bilateral orbital roof
defects.
Lars Frisén, J Löfgren
Acta neurochirurgica - 1978 -
Sectorial optic atrophy and homonymous, horizontal sectoranopia: a lateral choroidal artery
syndrome?
Lars Frisén, L Holmegaard, M Rosencrantz
Journal of neurology, neurosurgery, and psychiatry - 1978 -
Lateropulsion of the eyes--a localizing brainstem
sign.
Lars Frisén
Journal of neurology - 1978 -
Drusen in the optic nerve head. Verification by computerized
tomography.
Lars Frisén, G Schöldström, P Svendsen
Archives of ophthalmology (Chicago, Ill. : 1960) - 1978 -
Computed frontal tomography (CFT) of the orbit using the EMI CT 1010 head
scanner.
Lars Frisén, L Kjällman, P Svendsen
Neuroradiology - 1978 -
Relationship between perimetric eccentricity and retinal locus in a human eye. Comparison with theoretical
calculations.
Lars Frisén, G Schöldström
Acta ophthalmologica - 1977 -
Atrophy of optic nerve fibres in compression of the chiasm. Prognostic
implications.
M Lundström, Lars Frisén
Acta ophthalmologica - 1977 -
Contrast sensitivity in macular disease. A preliminary
report.
J Sjöstrand, Lars Frisén
Acta ophthalmologica - 1977 -
Sarcoid-like disorder of the intracranial optic
nerve.
Lars Frisén, S Lindgren, B J MacGregor, S Stattin
Journal of neurology, neurosurgery, and psychiatry - 1977 -
[The aqueduct
syndrome].
Lars Frisén
Lakartidningen - 1977 -
A simple relationship between the probability distribution of visual acuity and the density of retinal output
channels.
Lars Frisén, M Frisén
Acta ophthalmologica - 1976 -
Atrophy of optic nerve fibres in compression of the chiasm. Degree and distribution of ophthalmoscopic
changes.
M Lundström, Lars Frisén
Acta ophthalmologica - 1976 -
Cyclic compression of the intracranial optic nerve: patterns of visual failure and
recovery.
Lars Frisén, J Sjöstrand, K Norrsell, S Lindgren
Journal of neurology, neurosurgery, and psychiatry - 1976 -
Objective recognition of abnormal
isopters.
Lars Frisén, M Frisén
Acta ophthalmologica - 1975 -
Optical and neural resolution in peripheral
vision.
Lars Frisén, A Glansholm
Investigative ophthalmology - 1975 -
Evolution of descending optic atrophy. A case
report.
M Lundström, Lars Frisén
Acta ophthalmologica - 1975 -
An ideal test object for the tangent
screen.
Lars Frisén
Acta ophthalmologica - 1974 -
[Amaurosis fugax--differential diagnosis and
treatment].
Lars Frisén
Lakartidningen - 1974 -
Insidious atrophy of retinal nerve fibers in multiple sclerosis. Funduscopic identification in patients with and without visual
complaints.
Lars Frisén, W F Hoyt
Archives of ophthalmology (Chicago, Ill. : 1960) - 1974 -
Unsharp masking in fundus
photography.
Lars Frisén, W F Hoyt
Investigative ophthalmology - 1973 -
Optociliary veins, disc pallor and visual loss. A triad of signs indicating spheno-orbital
meningioma.
Lars Frisén, W F Royt, B M Tengroth
Acta ophthalmologica - 1973 -
A versatile color confrontation test for the central visual field. A comparison with quantitative
perimetry.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1973 -
[Optokinetic nystagmus in neurological focal
diagnosis].
Lars Frisén
Lakartidningen - 1973 -
Diagnostic uses of the Pulfrich
phenomenon.
Lars Frisén, W F Hoyt, A C Bird, R A Weale
Lancet (London, England) - 1973 -
Fundoscopy of nerve fiber layer defects in
glaucoma.
Lars Frisén, N M Newman
Investigative ophthalmology - 1973 -
Resolution at low contrast with a fundus camera. Comparison of various photographic
films.
Lars Frisén
Investigative ophthalmology - 1973 -
An adjustable biomicroscopy contact glass with erect
imagery.
Lars Frisén
Archives of ophthalmology (Chicago, Ill. : 1960) - 1972 -
Illumination box for colour vision
tests.
Lars Frisén, A Hedin
Acta ophthalmologica - 1972 -
Forced motion attachment for the Goldmann
perimeter.
Lars Frisén
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde - 1972 -
Genuine, relative binasal hemianopia. Report of a
case.
Lars Frisén
Acta ophthalmologica - 1971 -
The cartographic deformations of the visual
field.
Lars Frisén
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde - 1970 -
On objective analysis in kinetic
perimetry.
Lars Frisén
Acta ophthalmologica - 1970 -
Integral arc illumination for projection
perimeters.
Lars Frisén
Acta ophthalmologica - 1969 -
Effects of hypophysectomy and thyroxine on volume and biochemistry of orbital tissue in the crucian carp (Carassius carassius
L.).
Lars Frisén, G Prame
Experimental eye research - 1968 -
Simultaneous bioassay of exophthalmos-producing and thyrotrophic substances. I. The EPS
assay.
Lars Frisén
Acta endocrinologica - 1968 -
Simultaneous bioassay of exophthalmos-producing and thyrotrophic substances. II. The TSH
assays.
Lars Frisén
Acta endocrinologica - 1968 -
Critical analysis of exophthalmometry. An experimental evaluation of conventional and extended
method.
Lars Frisén
Acta ophthalmologica - 1967 -
Reliability of intraperitoneal injections in
fish.
Lars Frisén
Experientia - 1967 -
Analysis of the topographic distribution of thyroid activity in a teleost fish: Carassius carassius
L.
Lars Frisén, M Frisén
Acta endocrinologica - 1967 -
Rapid transmandibular hypophysectomy of small
fish.
Lars Frisén
Experientia - 1967 -
On the occurrence and nature of exophthalmogenic substances, especially in human
serum.
Lars Frisén, B Tengroth
Acta ophthalmologica - 1965 -
An improved method for the assay of exophthalmos-producing
substance.
B Tengroth, R Brunish, Lars Frisén
Acta ophthalmologica - 1964 -
A CYTOTOXIC SERUM FACTOR IN HEART DISEASE, ESPECIALLY
MYOCARDITIS.
S BENGMARK, Lars Frisén, E HELANDER
Acta allergologica - 1963