- Hem
- Om universitetet
- Hitta person
- Lisa Nilsson
Lisa Nilsson
Forskningsingenjör
Avd för kirurgi-
Patient-derived xenografts and single-cell sequencing identifies three subtypes of tumor-reactive lymphocytes in uveal melanoma
metastase
Joakim Karlsson, Vasu R. Sah, Roger Olofsson Bagge, Irina Kuznetsova, Munir Iqba, Samuel Alsén, Sofia Stenqvist, Alka Saxena, Lars Ny, Lisa M Nilsson, Jonas A Nilsson
ELIFE - 2024 -
Treatment with Anti-HER2 Chimeric Antigen Receptor Tumor-Infiltrating Lymphocytes (CAR-TILs) Is Safe and Associated with Antitumor Efficacy in Mice and Companion
Dogs
Elin Forsberg, Rebecca E Riise, S. Saellstrom, Joakim Karlsson, Samuel Alsén, Valentina Bucher, A. E. Hemminki, Roger Olofsson Bagge, Lars Ny, Lisa M Nilsson, H. Ronnberg, Jonas A Nilsson
Cancers - 2023 -
Genetics and Therapeutic Responses to Tumor-infiltrating Lymphocyte Therapy of Pancreatic Cancer Patient-derived Xenograft
Models
Caroline Vilhav, Lisa M Nilsson, Joakim Karlsson, Johan Bourghardt Fagman, Daniel Giglio, Cecilia Engström, Peter Naredi, Jonas A Nilsson
HPB - 2023 -
A Fraction of CD8+T Cells from Colorectal Liver Metastases Preferentially Repopulate Autologous Patient-Derived Xenograft Tumors as Tissue-Resident Memory T
Cells
Frank Liang, Lisa M Nilsson, Fabian Byvald, Azar Rezapour, Helena Taflin, Jonas A Nilsson, Ulf Yrlid
Cancers - 2022 -
Epigenetic therapy to enhance therapeutic effects of PD-1 inhibition in therapy-resistant
melanoma
Vasu R. Sah, Joakim Karlsson, Henrik Jespersen, Mattias F Lindberg, Lisa M Nilsson, Lars Ny, Jonas A Nilsson
Melanoma Research - 2022 -
Genetics and Therapeutic Responses to Tumor-Infiltrating
Lymphocyte Therapy of Pancreatic Cancer Patient-Derived
Xenograft
Models
Lisa M Nilsson, Caroline Vilhav, Joakim Karlsson, Johan Bourghardt Fagman, Daniel Giglio, Cecilia Engström, Peter Naredi, Jonas A Nilsson
Gastro Hep Advances - 2022 -
The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal
melanoma
Lars Ny, Henrik Jespersen, Joakim Karlsson, Samuel Alsén, Stefan Filges, C. All-Eriksson, B. Andersson, A. Carneiro, H. Helgadottir, Max Levin, I. Ljuslinder, Roger Olofsson Bagge, Vasu R. Sah, Ulrika Stierner, Anders Ståhlberg, G. Ullenhag, Lisa M Nilsson, Jonas A Nilsson
Nature Communications - 2021 -
BET bromodomain inhibitor HMBA synergizes with MEK inhibition in treatment of malignant
glioma
Elisa Funck-Brentano, Dzeneta Vizlin-Hodzic, Jonas A Nilsson, Lisa M Nilsson
Epigenetics - 2021 -
The Microenvironment of Small Intestinal Neuroendocrine Tumours Contains Lymphocytes Capable of Recognition and Activation after
Expansion
Tobias Hofving, Frank Liang, Joakim Karlsson, Ulf Yrlid, Jonas A Nilsson, Ola Nilsson, Lisa M Nilsson
Cancers - 2021 -
Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer
cells
Somsundar Veppil Muralidharan, Lisa M Nilsson, Mattias F Lindberg, Jonas A Nilsson
Life Science Alliance - 2020 -
Molecular profiling of driver events in metastatic uveal
melanoma
Joakim Karlsson, Lisa M Nilsson, Suman Mitra, Samuel Alsén, Ganesh V Shelke, Vasu R. Sah, Elin Forsberg, Ulrika Stierner, C. All-Eriksson, Berglind Osk Einarsdottir, Henrik Jespersen, Lars Ny, Per Lindnér, Erik Larsson, Roger Olofsson Bagge, Jonas A Nilsson
Nature Communications - 2020 -
SUMO pathway inhibition targets an aggressive pancreatic cancer
subtype
A. Biederstädt, Z. Hassan, C. Schneeweis, M. Schick, L. Schneider, A. Muckenhuber, Y. Hong, G. Siegers, Lisa M Nilsson, M. Wirth, Z. Dantes, K. Steiger, K. Schunck, S. Langston, H. P. Lenhof, A. Coluccio, F. Orben, J. Slawska, A. Scherger, D. Saur, S. Müller, R. Rad, W. Weichert, Jonas A Nilsson, M. Reichert, G. Schneider, U. Keller
Gut - 2020 -
Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse
models
Lars Ny, Larissa Rizzo, Valerio Belgrano, Jón Karlsson, Henrik Jespersen, Louise Carstam, Roger Olofsson Bagge, Lisa M Nilsson, Jonas A Nilsson
Annals of Oncology - 2020 -
HER2 CAR-T Cells Eradicate Uveal Melanoma and T-cell Therapy-Resistant Human Melanoma in IL2 Transgenic NOD/SCID IL2 Receptor Knockout
Mice
Elin Forsberg, Mattias F Lindberg, Henrik Jespersen, Samuel Alsén, Roger Olofsson Bagge, M. Donia, I. M. Svane, Ola Nilsson, Lars Ny, Lisa M Nilsson, Jonas A Nilsson
Cancer Research - 2019 -
Concomitant use of pembrolizumab and entinostat in adult patients with metastatic uveal melanoma (PEMDAC study): protocol for a multicenter phase II open label
study.
Henrik Jespersen, Roger Olofsson Bagge, Gustav Ullenhag, Ana Carneiro, Hildur Helgadottir, Ingrid Ljuslinder, Max Levin, Charlotta All-Eriksson, Bengt Andersson, Ulrika Stierner, Lisa M Nilsson, Jonas A Nilsson, Lars Ny
BMC cancer - 2019 -
A patient-derived xenograft pre-clinical trial reveals treatment responses and a resistance mechanism to karonudib in metastatic
melanoma
Berglind Osk Einarsdottir, Joakim Karlsson, Elin Söderberg, Mattias F Lindberg, Elisa Funck-Brentano, Henrik Jespersen, Siggeir Fannar Brynjólfsson, Roger Olofsson Bagge, Louise Carstam, M. Scobie, T. Koolmeister, O. Wallner, Ulrika Stierner, U. W. Berglund, Lars Ny, Lisa M Nilsson, Erik Larsson, T. Helleday, Jonas A Nilsson
Cell Death & Disease - 2018 -
BET bromodomain inhibitors synergize with ATR inhibitors in melanoma in
melanoma.
Somsundar Veppil Muralidharan, Berglind Osk Einarsdottir, Joydeep Bhadury, Mattias F Lindberg, Jin Wu, Eric Campeau, Roger Olofsson Bagge, Ulrika Stierner, Lars Ny, Lisa M Nilsson, Jonas A Nilsson
Cell Death & Disease - 2017 -
Clinical responses to adoptive T-cell transfer can be modeled in an autologous immune-humanized mouse
model.
Henrik Jespersen, Mattias F Lindberg, Marco Donia, Elin Söderberg, Rikke Andersen, Ulrich Keller, Lars Ny, Inge Marie Svane, Lisa M Nilsson, Jonas A Nilsson
Nature communications - 2017 -
Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain
Proteins
Lisa M Nilsson, Lydia C. Green, Somsundar Veppil Muralidharan, Dagsu Demir, M. Welin, Joydeep Bhadury, D. T. Logan, B. Walse, Jonas A Nilsson
Cancer Research - 2016 -
RNAi delivery by exosome-mimetic nanovesicles - Implications for targeting c-Myc in
cancer
Taral R Lunavat, Su Chul Jang, Lisa M Nilsson, Hyun Taek Park, Gabriela Repiska, Cecilia Lässer, Jonas A Nilsson, Yong Song Gho, Jan Lötvall
Biomaterials - 2016 -
BET bromodomain inhibitors synergize with ATR inhibitors to induce DNA damage, apoptosis, senescence-associated secretory pathway and ER stress in Myc-induced lymphoma
cells.
Somsundar Veppil Muralidharan, Joydeep Bhadury, Lisa M Nilsson, Lydia C. Green, K G McLure, Jonas A Nilsson
Oncogene - 2016 -
DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate
Immunity.
Anetta Härtlova, Saskia F Erttmann, Faizal Am Raffi, Anja M Schmalz, Ulrike Resch, Sharath Anugula, Stefan Lienenklaus, Lisa M Nilsson, Andrea Kröger, Jonas A Nilsson, Torben Ek, Siegfried Weiss, Nelson O Gekara
Immunity - 2015 -
Melanoma patient-derived xenografts accurately model the disease and develop fast enough to guide treatment
decisions.
Berglind Osk Einarsdottir, Roger Olofsson Bagge, Joydeep Bhadury, Henrik Jespersen, Jan Mattsson, Lisa M Nilsson, Katarina Truvé, Marcela Davila Lopez, Peter Naredi, Ola Nilsson, Ulrika Stierner, Lars Ny, Jonas A Nilsson
Oncotarget - 2014 -
Myc-induced SUMOylation is a therapeutic vulnerability for B-cell
lymphoma.
Alexander Hoellein, Mohammad Fallahi, Stephanie Schoeffmann, Sabine Steidle, Franz X Schaub, Martina Rudelius, Iina Laitinen, Lisa M Nilsson, Andrei Goga, Christian Peschel, Jonas A Nilsson, John L Cleveland, Ulrich Keller
Blood - 2014 -
BET and HDAC inhibitors induce similar genes and biological effects and synergize to kill in Myc-induced murine
lymphoma
Joydeep Bhadury, Lisa M Nilsson, Somsundar Veppil Muralidharan, L. C. Green, Z. L. Li, E. M. Gesner, H. C. Hansen, U. B. Keller, K. G. McLure, Jonas A Nilsson
Proceedings of the National Academy of Sciences of the United States of America - 2014 -
Identification of tumorigenic and therapeutically actionable mutations in transplantable mouse tumor cells by exome
sequencing.
Joydeep Bhadury, Marcela Davila Lopez, Somsundar Veppil Muralidharan, Lisa M Nilsson, Jonas A Nilsson
Oncogenesis - 2013 -
Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during
tumorigenesis.
Lisa M Nilsson, Tacha Zi Plym Forshell, Sara Rimpi, Christiane Kreutzer, Walter Pretsch, Georg W Bornkamm, Jonas A Nilsson
PLoS genetics - 2012 -
Therapeutic implications for the induced levels of Chk1 in Myc-expressing cancer
cells.
Andreas Höglund, Lisa M Nilsson, Somsundar Veppil Muralidharan, Lisa A Hasvold, Philip Merta, Martina Rudelius, Viktoriya Nikolova, Ulrich Keller, Jonas A Nilsson
Clinical cancer research : an official journal of the American Association for Cancer Research - 2011