Sidans innehåll
Development of inhibitors targetting Leukotoxins
Research project
Kort beskrivning
In this project we employ a range of bioinformatics tools such as homology modelling, protein-protein docking, binding site analyses and virtual screening/docking, as well as extensive molecular dynamics simulations, to identify new candidate drugs that are able to disrupt the alpha-beta-dimer interactions and thus disbale pore formation and reduce the bacterial virulence.