Länkstig

Thaher Pelaseyed

Forskare

Avd för medicinsk kemi och cellbiologi
Besöksadress
Medicinaregatan 9 A-B
41390 Göteborg
Postadress
Box 440
40530 Göteborg

Om Thaher Pelaseyed

Bacteria in our intestine exceed 10 trillions. In healthy individuals, an impermeable layer of secreted mucins separates bacteria from host intestinal cells.

In diseases such as Inflammatory bowel disease, bacteria breach the mucus barrier and reach epithelial cells covered with bottlebrush-like glycoproteins called transmembrane mucins. Despite the fact that transmembrane mucins extend up to 1 μm into the intestinal lumen and are ideal docking sites for penetrating bacteria, their biological function is unknown.

Our goal is to determine how transmembrane mucins sense bacteria and induce intestinal cell protection against bacterial infections.

Current funding and support: - Swedish Society for Medical Research, Start grant #S17-0005 (2018-2023) - NIH/NIAID/MIST Scholar Award in Mucosal Immunity (2018-2020) - Sahlgrenska Academy PhD Training Grant #U2018/162 (2019-2023) - The Wenner-Gren Foundations, Starting grant #FT2017-0002 (2017-2019) - The Wenner-Gren Foundations, International Postdoc Training grant, #UPD2018-0065 (2018-2020) - Åke Wiberg's Foundation, Research grant, #M17-0062 (2018-2019) - The Jeansson Foundations, Startup grant #JS2017-0003 (2018-2019)

Read more about our research and open positions here.