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- Marija Cvijovic
Marija Cvijovic
Professor
Avdelningen för tillämpad matematik och statistikOm Marija Cvijovic
Forskningen fokuserar på systembiologi av åldrande och protein-folding sjukdomar. För att närma sig dessa problem utvecklar gruppen specialiserade dynamiska modeller kompletterat med experimentellt arbete. Målet är att förstå de mekanismer som leder till bildandet av protein-folding sjukdomar och avser biokemiska cellulära processer till ett hälsosamt åldrande och livslängd. I strävan efter dessa mål kommer viktig vetenskaplig information att vara tillgänglig för att hantera viktiga prioriteringar för folkhälsopolitiken i framtiden.
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Exploring carbon source related localization and phosphorylation in the Snf1/Mig1 network using population and single cell-based
approaches
Svenja Braam, Farida Tripodi, Linnea Österberg, Sebastian Persson, Niek Welkenhuysen, Paola Coccetti, Marija Cvijovic
Microbial Cell (MIC) - 2024 -
Network medicine: facilitating a new view on complex
diseases
Marija Cvijovic, A. Polster
Frontiers in Bioinformatics - 2023 -
Scalable and flexible inference framework for stochastic dynamic single-cell
models
Sebastian Persson, Niek Welkenhuysen, Sviatlana Shashkova, Samuel Wiqvist, Patrick Reith, Gregor W. Schmidt, Umberto Picchini, Marija Cvijovic
PLoS Computational Biology - 2022 -
The choice of the objective function in flux balance analysis is crucial for predicting replicative lifespans in
yeast
Barbara Schnitzer, Linnea Österberg, Marija Cvijovic
Plos One - 2022 -
Multi-scale model suggests the trade-off between protein and ATP demand as a driver of metabolic changes during yeast replicative
ageing
Barbara Schnitzer, Linnea Österberg, Iro Skopa, Marija Cvijovic
PLoS Computational Biology - 2022 -
The effect of stress on biophysical characteristics of misfolded protein aggregates in living Saccharomyces cerevisiae
cells
Barbara Schnitzer, Niek Welkenhuysen, M. C. Leake, Sviatlana Shashkova, Marija Cvijovic
Experimental Gerontology - 2022 -
Optimizing study design in LPS challenge studies for quantifying drug induced inhibition of TNF? response: Did we miss the prime
time?
Julia Larsson, E. Hoppe, M. Gautrois, Marija Cvijovic, M. Jirstrand
European Journal of Pharmaceutical Sciences - 2022 -
The Effect of Lithium on the Budding Yeast Saccharomyces cerevisiae upon Stress
Adaptation
Patrick Reith, Svenja Braam, Niek Welkenhuysen, S. Lecinski, J. Shepherd, C. MacDonald, M. C. Leake, S. Hohmann, Sviatlana Shashkova, Marija Cvijovic
Microorganisms - 2022 -
Modelling of glucose repression signalling in yeast Saccharomyces
cerevisiae
Sebastian Persson, Sviatlana Shashkova, Linnea Österberg, Marija Cvijovic
FEMS Yeast Research - 2022 -
A novel stepwise integrative analysis pipeline reveals distinct microbiota-host interactions and link to symptoms in irritable bowel
syndrome
Annikka Polster, Lena Öhman, J. Tap, M. Derrien, B. Le Neve, Johanna Sundin, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Scientific Reports - 2021 -
Second-generation TNFα turnover model for improved analysis of test compound interventions in LPS challenge
studies
Julia Larsson, E. Hoppe, M. Gautrois, Marija Cvijovic, M. Jirstrand
European Journal of Pharmaceutical Sciences - 2021 -
A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and
metabolism
Linnea Österberg, Julia Münch, J. Nielsen, S. Hohmann, Marija Cvijovic
Plos Computational Biology - 2021 -
Cell polarisation in a bulk-surface model can be driven by both classic and non-classic Turing
instability
Johannes Borgqvist, Adam A. Malik, Carl Lundholm, Anders Logg, Philip Gerlee, Marija Cvijovic
Npj Systems Biology and Applications - 2021 -
The synergy of damage repair and retention promotes rejuvenation and prolongs healthy lifespans in cell
lineages
Barbara Schnitzer, Johannes Borgqvist, Marija Cvijovic
PLoS Computational Biology - 2020 -
Fine-Tuning of Energy Levels Regulates SUC2 via a SNF1-Dependent Feedback
Loop
Sebastian Persson, Niek Welkenhuysen, Sviatlana Shashkova, Marija Cvijovic
Frontiers in Physiology - 2020 -
Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative
ageing
Johannes Borgqvist, Niek Welkenhuysen, Marija Cvijovic
Scientific Reports - 2020 -
Mig1 localization exhibits biphasic behavior which is controlled by both metabolic and regulatory roles of the sugar
kinases
G. W. Schmidt, Niek Welkenhuysen, Ye Tian, Marija Cvijovic, Stefan Hohmann
Molecular Genetics and Genomics - 2020 -
Symmetry structures in dynamic models of biochemical
systems
Fredrik Ohlsson, Johannes Borgqvist, Marija Cvijovic
Journal of the Royal Society Interface - 2020 -
Robustness of Nutrient Signaling Is Maintained by Interconnectivity Between Signal Transduction
Pathways
Niek Welkenhuysen, Barbara Schnitzer, Linnea Österberg, Marija Cvijovic
Frontiers in Physiology - 2019 -
Adaptive damage retention mechanism enables healthier yeast
population
Qasim Ali, Riccardo Dainese, Marija Cvijovic
Journal of Theoretical Biology - 2019 -
Cardiac troponin T concentrations and patient-specific risk of myocardial infarction using the novel PALfx
parameter.
Damiano Ognissanti, Christian Bjurman, Martin J Holzmann, Elvar Theodorsson, Max Petzold, Marija Cvijovic, Ola Hammarsten
Clinical biochemistry - 2019 -
Modelling of oscillatory cortisol response in horses using a Bayesian population approach for evaluation of dexamethasone suppression test
protocols
Felix Held, C. Ekstrand, Marija Cvijovic, J. Gabrielsson, M. Jirstrand
Journal of Pharmacokinetics and Pharmacodynamics - 2019 -
Challenge model of TNFα turnover at varying LPS and drug
provocations
Felix Held, E. Hoppe, Marija Cvijovic, M. Jirstrand, J. Gabrielsson
Journal of Pharmacokinetics and Pharmacodynamics - 2019 -
Creating an automated micromanipulator with a microfluidics and optical tweezers approach to study replicative
ageing
Niek Welkenhuysen, Martin Mojica Benavides, Caroline B. Adiels, Giovanni Volpe, Marija Cvijovic
OSA The Optical Society - 2019 -
Heart rate variability characteristics of patients with irritable bowel syndrome and associations with
symptoms
Annikka Polster, Peter Friberg, Veronica Gunterberg, Lena Öhman, B. Le Neve, Hans Törnblom, Marija Cvijovic, Magnus Simrén
Neurogastroenterology and Motility - 2018 -
Bayesian hierarchical model of oscillatory cortisol response during drug
intervention
Felix Held, Carl Ekstrand, Edmund Hoppe, Marija Cvijovic, Johan Gabrielsson, Mats Jirstrand
27th meeting of the Population Approach Group in Europe Montreux, Switzerland, 2018-05-29 - 2018-06-01 - 2018 -
Focus on
resolution
Stefan Hohmann, Marija Cvijovic
Current Opinion in Systems Biology - 2018 -
Single-cell study links metabolism with nutrient signaling and reveals sources of
variability
Niek Welkenhuysen, Johannes Borgqvist, Mattias Backman, Loubna Bendrioua, Mattias Goksör, Caroline B. Adiels, Marija Cvijovic, Stefan Hohmann
Bmc Systems Biology - 2017 -
Systems Biology of
Aging
Johannes Borgqvist, Riccardo Dainese, Marija Cvijovic
Systems Biology, VI. Jens Nielsen Stefan Hohmann (red.) - 2017 -
Bridging the gaps in systems
biology
Marija Cvijovic, Joachim Almquist, Jonas Hagmar, Stefan Hohmann, H. M. Kaltenbach, E. Klipp, M. Krantz, P. Mendes, S. Nelander, Jens B. Nielsen, A. Pagnani, N. Przulj, A. Raue, J. Stelling, S. Stoma, F. Tobin, J. A. H. Wodke, R. Zecchina, Mats Jirstrand
Molecular Genetics and Genomics - 2014 -
Kinetic models in industrial biotechnology - Improving cell factory
performance
Joachim Almquist, Marija Cvijovic, V. Hatzimanikatis, Jens B. Nielsen, Mats Jirstrand
Metabolic Engineering - 2014 -
Yeast AMP-activated protein kinase monitors glucose concentration changes and absolute glucose
levels
Loubna Bendrioua, Maria Smedh, Joachim Almquist, Marija Cvijovic, Mats Jirstrand, Mattias Goksör, Caroline B. Adiels, Stefan Hohmann
Journal of Biological Chemistry - 2014 -
Essential Genetic Interactors of SIR2 Required for Spatial Sequestration and Asymmetrical Inheritance of Protein
Aggregates
J. Song, Q. Yang, Junsheng Yang, Lisa C Larsson, Xinxin Hao, Xuefeng Zhu, Sandra Malmgren Hill, Marija Cvijovic, Julia Fernandez-Rodriguez, Julie Grantham, Claes M Gustafsson, Beidong Liu, Thomas Nyström
PLoS Genetics - 2014 -
Stress granule-defective mutants deregulate stress responsive
transcripts
Xiaoxue Yang, Yi Shen, Elena Garre, Xinxin Hao, Daniel Krumlinde, Marija Cvijovic, Christina Arens, Thomas Nyström, Beidong Liu, Per Sunnerhagen
PLoS Genetics - 2014 -
yApoptosis: yeast apoptosis
database
Kwanjeera Wanichthanarak, Marija Cvijovic, Andrea Molt, Dina Petranovic
DATABASE - THE JOURNAL OF BIOLOGICAL DATABASES AND CURATION - 2013 -
Removal of damaged proteins during ES cell fate specification requires the proteasome activator
PA28
Malin Hernebring, Åsa Fredriksson, M. Liljevald, Marija Cvijovic, K. Norrman, J. Wiseman, Henrik Semb, Thomas Nyström
Scientific Reports - 2013 -
Boolean model of yeast apoptosis as a tool to study yeast and human apoptotic
regulations
Laleh Kazemzadeh, Marija Cvijovic, Dina Petranovic
Frontiers in Physiology - 2012 -
Global hepatic gene expression in rainbow trout exposed to sewage effluents: A comparison of different sewage treatment
technologies
Filip Cuklev, Lina-Maria Gunnarsson, Marija Cvijovic, Erik Kristiansson, Carolin Rutgersson, B. Bjorlenius, D. G. Joakim Larsson
Science of the Total Environment - 2012 -
Does ketoprofen or diclofenac pose the lowest risk to
fish?
Filip Cuklev, J. Fick, Marija Cvijovic, Erik Kristiansson, Lars Förlin, D. G. Joakim Larsson
Journal of Hazardous Materials - 2012 -
Mathematical models of cell factories: moving towards the core of industrial
biotechnology
Marija Cvijovic, Sergio Bordel Velasco, Jens B. Nielsen
Microbial Biotechnology - 2011 -
BioMet Toolbox: genome-wide analysis of
metabolism
Marija Cvijovic, Roberto Olivares Hernandez, Rasmus Ågren, Niklas Dahr, Wanwipa Vongsangnak, Intawat Nookaew, K. R. Patil, Jens B. Nielsen
Nucleic Acids Research - 2010 -
Selective benefits of damage partitioning in unicellular systems and its effects on
aging
Nika Erjavec, Marija Cvijovic, E. Klipp, Thomas Nyström
Proceedings of The National Academy of Sciences of The United States of America - 2008 -
Identification of putative regulatory upstream ORFs in the yeast genome using heuristics and evolutionary
conservation
Marija Cvijovic, Daniel Dalevi, Elizabeth Bilsland, Graham J.L. Kemp, Per Sunnerhagen
BMC Bioinformatics - 2007