- Hem
- Om universitetet
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- Matti Poutanen
Matti Poutanen
Forskare
Avd för invärtesmedicin och klinisk nutrition-
Postnatal Dysregulation of Androgens in Extremely Preterm Male
Infants
Anders K. Nilsson, Ulrika Sjöbom, Andreas Landin, Mats X. Andersson, Henrik Ryberg, Aldina Pivodic, Chatarina Löfqvist, Karin Sävman, Matti Poutanen, Claes Ohlsson, Ann Hellström
JOURNAL OF THE ENDOCRINE SOCIETY - 2024 -
Superior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist
therapy
Miguel A. Sanchez-Garrido, Victor Serrano-Lopez, Francisco Ruiz-Pino, Maria Jesus Vazquez, Andrea Rodriguez-Martin, Encarnacion Torres, Inmaculada Velasco, Ana Belen Rodriguez, Eduardo Chicano-Galvez, Marina Mora-Ortiz, Claes Ohlsson, Matti Poutanen, Leonor Pinilla, Francisco Gaytan, Jonathan D. Douros, Bin Yang, Timo D. Mueller, Richard D. Dimarchi, Matthias H. Tschoep, Brian Finan, Manuel Tena-Sempere
NATURE COMMUNICATIONS - 2024 -
Profiling fi ling steroid hormone landscape of bladder cancer reveals depletion of intratumoural androgens to castration levels: a cross-sectional
study
Kimmo Kettunen, Julia Mathlin, Tarja Lamminen, Asta Laiho, Merja R. Hakkinen, Seppo Auriola, Laura L. Elo, Peter J. Bostrom, Matti Poutanen, Pekka Taimen
EBIOMEDICINE - 2024 -
Disruption of HSD17B12 in mouse hepatocytes leads to reduced body weight and defect in the lipid droplet expansion associated with microvesicular
steatosis
Hanna Heikela, Laura Mairinoja, Suvi T. Ruohonen, Kalle T. Rytkonen, Simone de Brot, Asta Laiho, Satu Koskinen, Tomi Suomi, Laura L. Elo, Leena Strauss, Matti Poutanen
FASEB JOURNAL - 2024 -
HSD17B1 Compensates for HSD17B3 Deficiency in Fetal Mouse Testis but Not in
Adults.
Arttu Junnila, Fu-Ping Zhang, Guillermo Martínez Nieto, Janne Hakkarainen, Juho-Antti Mäkelä, Claes Ohlsson, Petra Sipilä, Matti Poutanen
Endocrinology - 2024 -
Consistent and effective method to define the mouse estrous cycle stage by deep learning based
model.
Leena Strauss, Arttu Junnila, Anni Wärri, Maria Manti, Yiwen Jiang, Eliisa Löyttyniemi, Elisabet Stener-Victorin, Marie K Lagerquist, Krisztina Kukoricza, Taija Heinosalo, Sami Blom, Matti Poutanen
Journal of Endocrinology - 2024 -
RUNX transcription factors are essential in maintaining epididymal epithelial
differentiation.
Mervi Toriseva, Ida Björkgren, Arttu Junnila, Arfa Mehmood, Jesse Mattsson, Inka Raimoranta, Bongki Kim, Asta Laiho, Matthias Nees, Laura Elo, Matti Poutanen, Sylvie Breton, Petra Sipilä
Cellular and molecular life sciences : CMLS - 2024 -
Differences in Gut Microbiota Profiles and Microbiota Steroid Hormone Biosynthesis in Men with and Without Prostate
Cancer.
Sofia Kalinen, Teemu Kallonen, Marianne Gunell, Otto Ettala, Ivan Jambor, Juha Knaapila, Kari T Syvänen, Pekka Taimen, Matti Poutanen, Hannu J Aronen, Helena Ollila, Sami Pietilä, Laura L Elo, Tarja Lamminen, Antti J Hakanen, Eveliina Munukka, Peter J Boström
European urology open science - 2024 -
Elevated chorionic gonadotropic hormone in transgenic mice induces parthenogenetic activation and ovarian
teratomas.
Susana B Rulli, Petteri Ahtiainen, Laura D Ratner, Kim Jonas, Ricardo S Calandra, Matti Poutanen, Ilpo Huhtaniemi
Molecular and Cellular Endocrinology - 2024 -
Sex steroid levels in women with hypopituitarism: A case-controlled observational
study.
Catharina Olivius, Kerstin Landin-Wilhelmsen, Claes Ohlsson, Matti Poutanen, Penelope Trimpou, Daniel S Olsson, Gudmundur Johannsson, Åsa Tivesten
The Journal of clinical endocrinology and metabolism - 2024 -
Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in
mice.
Salli Talvi, Johanna Jokinen, Kalle Sipilä, Pekka Rappu, Fu-Ping Zhang, Matti Poutanen, Pia Rantakari, Jyrki Heino
iScience - 2024 -
Gene expression profiles separate endometriosis lesion subtypes and indicate a sensitivity of endometrioma to estrogen suppressive treatments through elevated ESR2
expression.
Sushma Marla, Sally Mortlock, Taija Heinosalo, Matti Poutanen, Grant W Montgomery, Brett David McKinnon
BMC medicine - 2023 -
Targeting sex steroid biosynthesis for breast and prostate cancer
therapy
Matti Poutanen, Malin Hagberg Thulin, Pirkko Härkönen
Nature Reviews Cancer - 2023 -
Dietary Progesterone Contributes to Intratissue Levels of Progesterone in Male
Mice
Hannah Colldén, Malin Hagberg Thulin, A. Landin, Karin Horkeby, Marie Lagerquist, Jianyao Wu, Karin H. Nilsson, Louise Grahnemo, Matti Poutanen, H. Ryberg, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2023 -
Deep Learning-Based Image Analysis of Liver Steatosis in Mouse
Models
L. Mairinoja, H. Heikela, S. Blom, D. Kumar, A. Knuuttila, S. Boyd, N. Sjoblom, E. M. Birkman, P. Rinne, P. Ruusuvuori, L. Strauss, Matti Poutanen
American Journal of Pathology - 2023 -
The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene
expression.
Juha Saarikettu, Saara Lehmusvaara, Marko Pesu, Ilkka Junttila, Juha Partanen, Petra Sipilä, Matti Poutanen, Jie Yang, Teemu Haikarainen, Olli Silvennoinen
FASEB bioAdvances - 2023 -
Persistently expressed human chorionic gonadotropin induces premature luteinization and progressive alterations on the reproductive axis in female
mice.
Agustina Marcial Lopez, Laura D Ratner, Carolina S Martinez, Noelia Di Giorgio, Matti Poutanen, Ilpo T Huhtaniemi, Susana B Rulli
General and comparative endocrinology - 2023 -
Dissecting the KNDy hypothesis: KNDy neuron-derived kisspeptins are dispensable for puberty but essential for preserved female fertility and gonadotropin
pulsatility.
Inmaculada Velasco, Delphine Franssen, Silvia Daza-Dueñas, Katalin Skrapits, Szabolcs Takács, Encarnación Torres, Elvira Rodríguez-Vazquez, Miguel Ruiz-Cruz, Silvia León, Krisztina Kukoricza, Fu-Ping Zhang, Suvi Ruohonen, Diego Luque-Cordoba, Feliciano Priego-Capote, Francisco Gaytan, Francisco Ruiz-Pino, Erik Hrabovszky, Matti Poutanen, María J Vázquez, Manuel Tena-Sempere
Metabolism: clinical and experimental - 2023 -
Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate
cancer.
Verneri Virtanen, Kreetta Paunu, Antti Kukkula, Saana Niva, Ylva Junila, Mervi Toriseva, Terhi Jokilehto, Sari Mäkelä, Riikka Huhtaniemi, Matti Poutanen, Ilkka Paatero, Maria Sundvall
Oncogenesis - 2023 -
Serum DHEA and Testosterone Levels Associate Inversely With Coronary Artery Calcification in Elderly
Men
Claes Ohlsson, Maria Nethander, A. K. Norlen, Matti Poutanen, E. F. Gudmundsson, T. Aspelund, S. Sigurdsson, H. Ryberg, V. Gudnason, Åsa Tivesten
Journal of Clinical Endocrinology & Metabolism - 2023 -
Physiological levels of estradiol limit murine osteoarthritis
progression
Carmen Corciulo, Julia M. Scheffler, Piotr Humeniuk, Alicia M. del Carpio Pons, Alexandra Stubelius, U. Von Mentzer, Christina Drevinge, Aidan Barrett, Sofia Wüstenhagen, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
Journal of Endocrinology - 2022 -
Preterm infant circulating sex steroid levels are not altered by transfusion with adult male plasma: a retrospective multicentre cohort
study
Anders K. Nilsson, Gunnel Hellgren, Ulrika Sjöbom, Andreas Landin, Henrik Ryberg, D. Wackernagel, D. Ley, I. H. Pupp, Matti Poutanen, Claes Ohlsson, Ann Hellström
Archives of Disease in Childhood-Fetal and Neonatal Edition - 2022 -
Low Progesterone and Low Estradiol Levels Associate with Abdominal Aortic Aneurysms in
Men.
Claes Ohlsson, Marcus Langenskiöld, Kristian Smidfelt, Matti Poutanen, Henrik Ryberg, Anna-Karin Norlén, Joakim Nordanstig, Göran Bergström, Åsa Tivesten
The Journal of clinical endocrinology and metabolism - 2022 -
Dehydroepiandrosterone Supplementation Results in Varying Tissue-specific Levels of Dihydrotestosterone in Male
Mice
Hannah Colldén, Maria E. Nilsson, A. K. Norlen, A. Landin, S. H. Windahl, Jianyao Wu, Karin L Horkeby, Marie K Lagerquist, H. Ryberg, Matti Poutanen, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2022 -
Dicer ablation in Kiss1 neurons impairs puberty and fertility preferentially in female
mice
J. Roa, M. Ruiz-Cruz, F. Ruiz-Pino, R. Onieva, M. J. Vazquez, M. J. Sanchez-Tapia, J. M. Ruiz-Rodriguez, V. Sobrino, A. Barroso, V. Heras, I. Velasco, C. Perdices-Lopez, Claes Ohlsson, M. S. Avendano, V. Prevot, Matti Poutanen, L. Pinilla, F. Gaytan, M. Tena-Sempere
Nature Communications - 2022 -
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic
Mice
T. Heinosalo, K. T. Rytkonen, N. Saarinen, P. Jarvensivu, P. Damdimopoulou, L. Strauss, S. Orasniemi, P. Horshauge, M. Gabriel, P. Koskimies, Claes Ohlsson, P. Kronqvist, Matti Poutanen
International Journal of Molecular Sciences - 2022 -
Selective loss of kisspeptin signaling in oocytes causes progressive premature ovulatory
failure
S. T. Ruohonen, F. Gaytan, A. U. Gaudi, I. Velasco, K. Kukoricza, C. Perdices-Lopez, D. Franssen, I. Guler, A. Mehmood, L. L. Elo, Claes Ohlsson, Matti Poutanen, M. Tena-Sempere
Human Reproduction - 2022 -
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated
mice
R. Huhtaniemi, P. Sipila, A. Junnila, R. Oksala, M. Knuuttila, A. Mehmood, E. Aho, T. D. Laajala, T. Aittokallio, A. Laiho, L. Elo, Claes Ohlsson, Malin Hagberg Thulin, P. Kallio, S. Makela, M. V. J. Mustonen, Matti Poutanen
iScience - 2022 -
Comprehensive Sex Steroid Profiling in Multiple Tissues Reveals Novel Insights in Sex Steroid Distribution in Male
Mice
Hannah Colldén, Maria E. Nilsson, A. K. Norlen, A. Landin, S. H. Windahl, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, H. Ryberg, Liesbeth Vandenput, Claes Ohlsson
Endocrinology - 2022 -
Impact of Musashi-1 and Musashi-2 Double Knockdown on Notch Signaling and the Pathogenesis of
Endometriosis.
Theresa Strauß, Burkhard Greve, Michael Gabriel, Nurjannah Achmad, Dhanusha Schwan, Nancy Adriana Espinoza-Sanchez, Antonio Simone Laganà, Ludwig Kiesel, Matti Poutanen, Martin Götte, Sebastian Daniel Schäfer
International journal of molecular sciences - 2022 -
Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to
endometriosis.
Kalle T Rytkönen, Thomas Faux, Mehrad Mahmoudian, Taija Heinosalo, Mauris C Nnamani, Antti Perheentupa, Matti Poutanen, Laura L Elo, Günter P Wagner
iScience - 2022 -
The variant rs77559646 associated with aggressive prostate cancer disrupts ANO7 mRNA splicing and protein
expression.
Gudrun Wahlström, Samuel Heron, Matias Knuuttila, Elina Kaikkonen, Nea Tulonen, Olli Metsälä, Christoffer Löf, Otto Ettala, Peter J Boström, Pekka Taimen, Matti Poutanen, Johanna Schleutker
Human molecular genetics - 2022 -
Cell type markers indicate distinct contributions of decidual stromal cells and natural killer cells in
preeclampsia.
Kalle T Rytkönen, Nigatu Adossa, Mehrad Mahmoudian, Tapio Lönnberg, Matti Poutanen, Laura L Elo
Reproduction (Cambridge, England) - 2022 -
Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like
cells
K. Sepponen, K. Lundin, D. A. Yohannes, S. Vuoristo, D. Balboa, Matti Poutanen, Claes Ohlsson, S. Hustad, E. Bifulco, P. Paloviita, T. Otonkoski, O. Ritvos, K. Sainio, J. S. Tapanainen, T. Tuuri
Differentiation - 2022 -
Comparative Analysis of the Effects of Long-Term 3,5-diiodothyronine Treatment on the Murine Hepatic Proteome and Transcriptome Under Conditions of Normal Diet and High-Fat
Diet
J. Lietzow, J. Golchert, M. Pietzner, U. Volker, Matti Poutanen, Claes Ohlsson, G. Homuth, J. Kohrle
Thyroid - 2021 -
The androgen receptor depends on ligand-binding domain dimerization for transcriptional
activation
S. El Kharraz, V. Dubois, M. E. van Royen, A. B. Houtsmuller, E. Pavlova, N. Atanassova, T. Nguyen, A. Voet, R. Eerlings, F. Handle, S. Prekovic, E. Smeets, L. Moris, W. Devlies, Claes Ohlsson, Matti Poutanen, K. J. Verstrepen, G. Carmeliet, K. M. Launonen, L. Helminen, J. J. Palvimo, C. Libert, D. Vanderschueren, C. Helsen, F. Claessens
Embo Reports - 2021 -
Pulsed administration for physiological estrogen replacement in
mice
Carmen Corciulo, Julia M. Scheffler, Karin L. Gustafsson, Christina Drevinge, Piotr Humeniuk, Alicia M. del Carpio Pons, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
F1000Research - 2021 -
MALDI-IMS combined with shotgun proteomics identify and localize new factors in male
infertility.
Shibojyoti Lahiri, Wasim Aftab, Lena Walenta, Leena Strauss, Matti Poutanen, Artur Mayerhofer, Axel Imhof
Life science alliance - 2021 -
AMP-activated protein kinase (AMPK) signaling in GnRH neurons links energy status and
reproduction.
D Franssen, A Barroso, F Ruiz-Pino, M J Vázquez, D García-Galiano, J M Castellano, R Onieva, M Ruiz-Cruz, Matti Poutanen, F Gaytán, C Diéguez, L Pinilla, M Lopez, J Roa, M Tena-Sempere
Metabolism: clinical and experimental - 2021 -
Statistical Evaluation of Different Mathematical Models for Diffusion Weighted Imaging of Prostate Cancer Xenografts in
Mice.
Harri Merisaari, Hanne Laakso, Heidi Liljenbäck, Helena Virtanen, Hannu J Aronen, Heikki Minn, Matti Poutanen, Anne Roivainen, Timo Liimatainen, Ivan Jambor
Frontiers in oncology - 2021 -
Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular
cells.
Annika Missel, Lena Walenta, Katja Eubler, Nadine Mundt, Hanna Heikelä, Ulrich Pickl, Matthias Trottmann, Bastian Popper, Matti Poutanen, Leena Strauss, Frank-Michael Köhn, Lars Kunz, Marc Spehr, Artur Mayerhofer
Molecular human reproduction - 2021 -
Exploring the Ion Channel TRPV2 and Testicular Macrophages in Mouse
Testis.
Katja Eubler, Pia Rantakari, Heidi Gerke, Carola Herrmann, Annika Missel, Nina Schmid, Lena Walenta, Shibojyoti Lahiri, Axel Imhof, Leena Strauss, Matti Poutanen, Artur Mayerhofer
International journal of molecular sciences - 2021 -
Docetaxel chemotherapy response in PC3 prostate cancer mouse model detected by rotating frame relaxations and water
diffusion.
Hanne Laakso, Elias Ylä-Herttuala, Alejandra Sierra, Ivan Jambor, Matti Poutanen, Heidi Liljenbäck, Helena Virtanen, Harri Merisaari, Hannu Aronen, Heikki Minn, Anne Roivainen, Timo Liimatainen
NMR in biomedicine - 2021 -
Neonatal exposure to androgens dynamically alters gut microbiota
architecture
A. Barroso, J. A. Santos-Marcos, C. Perdices-Lopez, A. Vega-Rojas, M. A. Sanchez-Garrido, Y. Krylova, H. Molina-Abril, Claes Ohlsson, P. Perez-Martinez, Matti Poutanen, J. Lopez-Miranda, M. Tena-Sempere, A. Camargo
Journal of Endocrinology - 2020 -
Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male
mice.
Juan Antonio Aguilar-Pimentel, Yi-Li Cho, Raffaele Gerlini, Julia Calzada-Wack, Maria Wimmer, Philipp Mayer-Kuckuk, Thure Adler, Carsten B Schmidt-Weber, Dirk H Busch, Helmut Fuchs, Valérie Gailus-Durner, Markus Ollert, Martin Hrabě de Angelis, Claes Ohlsson, Matti Poutanen, Raffaele Teperino, Leena Strauss
Scientific reports - 2020 -
Erbb4 regulates the oocyte microenvironment during
folliculogenesis.
Ville Veikkolainen, Nsrein Ali, Milena Doroszko, Antti Kiviniemi, Ilkka Miinalainen, Claes Ohlsson, Matti Poutanen, Nafis Rahman, Klaus Elenius, Seppo J Vainio, Florence Naillat
Human molecular genetics - 2020 -
Interplay between gonadal hormones and postnatal overfeeding in defining sex-dependent differences in gut microbiota
architecture.
Jose A Santos-Marcos, Alexia Barroso, Oriol A Rangel-Zuñiga, Cecilia Perdices-Lopez, Carmen Haro, Miguel A Sanchez-Garrido, Helena Molina-Abril, Claes Ohlsson, Pablo Perez-Martinez, Matti Poutanen, Jose Lopez-Miranda, Francisco Perez-Jimenez, Manuel Tena-Sempere, Antonio Camargo
Aging - 2020 -
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female
mice
Claes Ohlsson, Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Klara Sjögren, Anna E Törnqvist, Annica Andersson, Ulrika Islander, Angelina I Bernardi, Matti Poutanen, Pierre Chambon, Marie K Lagerquist
FASEB Journal - 2020 -
Generation of an all-exon Esr2 deleted mouse line: Effects on
fertility
P. Antonson, L. M. Apolinario, M. M. Shamekh, P. Humire, Matti Poutanen, Claes Ohlsson, I. Nalvarte, J. A. Gustafsson
Biochemical and Biophysical Research Communications - 2020 -
The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3
deficiency
P. Sipila, A. Junnila, J. Hakkarainen, R. Huhtaniemi, L. Mairinoja, F. P. Zhang, L. Strauss, Claes Ohlsson, N. Kotaja, I. Huhtaniemi, Matti Poutanen
Faseb Journal - 2020 -
A relational database to identify differentially expressed genes in the endometrium and endometriosis
lesions
M. Gabriel, V. Fey, T. Heinosalo, P. Adhikari, K. Rytkonen, T. Komulainen, K. Huhtinen, T. D. Laajala, H. Siitari, A. Virkki, P. Suvitie, H. Kujari, T. Aittokallio, A. Perheentupa, Matti Poutanen
Scientific Data - 2020 -
Hydroxysteroid (17 beta) dehydrogenase 12 is essential for metabolic homeostasis in adult
mice
H. Heikela, S. T. Ruohonen, M. Adam, R. Viitanen, H. Liljenback, O. Eskola, M. Gabriel, L. Mairinoja, A. Pessia, V. Velagapudi, A. Roivainen, F. P. Zhang, L. Strauss, Matti Poutanen
American Journal of Physiology-Endocrinology and Metabolism - 2020 -
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1
receptor
Fredrik Anesten, Adria Dalmau Gasull, Jennifer E. Richard, Imre Farkas, Devesh Mishra, Lilly Taing, F. Zhang, Matti Poutanen, Vilborg Palsdottir, Z. Liposits, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2019 -
Biology and clinical relevance of Hydroxysteroid (17beta) dehydrogenase
enzymes.
Matti Poutanen, Trevor M Penning
Molecular and cellular endocrinology - 2019 -
Applying mass spectrometric methods to study androgen biosynthesis and metabolism in prostate
cancer
M. Knuuttila, E. Hämäläinen, Matti Poutanen
Journal of molecular endocrinology - 2019 -
The gut microbiota is a major regulator of androgen metabolism in intestinal
contents.
Hannah Colldén, Andreas Landin, Ville Wallenius, Erik Elebring, Lars Fändriks, Maria E. Nilsson, Henrik Ryberg, Matti Poutanen, Klara Sjögren, Liesbeth Vandenput, Claes Ohlsson
American journal of physiology. Endocrinology and metabolism - 2019 -
Glucagon-Like Peptide-1-, but not Growth and Differentiation Factor 15-, Receptor Activation Increases the Number of Interleukin-6-Expressing Cells in the External Lateral Parabrachial
Nucleus
Fredrik Anesten, Devesh Mishra, Adria Dalmau Gasull, Linda Engström-Ruud, Jakob Bellman, Vilborg Palsdottir, F Zhang, S. Trapp, Karolina P Skibicka, Matti Poutanen, John-Olov Jansson
Neuroendocrinology - 2019 -
Lack of androgen receptor SUMOylation results in male infertility due to epididymal
dysfunction
F. P. Zhang, M. Malinen, A. Mehmood, T. Lehtiniemi, T. Jaaskelainen, E. A. Niskanen, H. Korhonen, A. Laiho, L. L. Elo, Claes Ohlsson, N. Kotaja, Matti Poutanen, P. Sipila, J. J. Palvimo
Nature Communications - 2019 -
Androgen receptor SUMOylation regulates bone mass in male
mice
Jianyao Wu, Sofia Moverare-Skrtic, F. P. Zhang, A. Koskela, J. Tuukkanen, J. J. Palvimo, P. Sipila, Matti Poutanen, Claes Ohlsson
Molecular and Cellular Endocrinology - 2019 -
Role of hydroxysteroid (17beta) dehydrogenase type 1 in reproductive tissues and hormone-dependent
diseases.
Taija Heinosalo, Niina Saarinen, Matti Poutanen
Molecular and cellular endocrinology - 2019 -
Europium Nanoparticle-Based Sialyl-Tn Monoclonal Antibody Discriminates Epithelial Ovarian Cancer-Associated CA125 from Benign
Sources.
Kamlesh Gidwani, Nimrah Nadeem, Kaisa Huhtinen, Henna Kekki, Taija Heinosalo, Johanna Hynninen, Antti Perheentupa, Matti Poutanen, Olli Carpen, Kim Pettersson, Urpo Lamminmäki
The journal of applied laboratory medicine - 2019 -
Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived
Cells.
Kimmo Kettunen, Peter J Boström, Tarja Lamminen, Taija Heinosalo, Gun West, Irena Saarinen, Katja Kaipio, Juha Rantala, Chris Albanese, Matti Poutanen, Pekka Taimen
European urology - 2019 -
Decidualization of Human Endometrial Stromal Fibroblasts is a Multiphasic Process Involving Distinct Transcriptional
Programs.
Kalle T Rytkönen, Eric M Erkenbrack, Matti Poutanen, Laura L Elo, Mihaela Pavlicev, Günter P Wagner
Reproductive Sciences - 2019 -
Hydroxysteroid (17 beta) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male
fertility
J. Hakkarainen, F. P. Zhang, H. Jokela, A. Mayerhofer, R. Behr, S. Cisneros-Montalvo, Mirja Nurmio, Jorma Toppari, Claes Ohlsson, N. Kotaja, P. Sipila, Matti Poutanen
Faseb Journal - 2018 -
WNT16 overexpression partly protects against glucocorticoid-induced bone
loss
Claes Ohlsson, Karin H. Nilsson, Petra Henning, Jianyao Wu, Karin L. Gustafsson, Matti Poutanen, Ulf H Lerner, Sofia Moverare-Skrtic
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
Intratumoral androgen levels are linked to TMPRSS2-ERG fusion in prostate
cancer
M. Knuuttila, A. Mehmood, J. Maki-Jouppila, Henrik Ryberg, P. Taimen, J. Knaapila, O. Ettala, P. J. Bostrom, Claes Ohlsson, M. S. Venalainen, A. Laiho, L. L. Elo, P. Sipila, S. I. Makela, Matti Poutanen
Endocrine-Related Cancer - 2018 -
Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer
Xenografts
R. Huhtaniemi, R. Oksala, M. Knuuttila, A. Mehmood, E. Aho, T. D. Laajala, D. Nicorici, T. Aittokallio, A. Laiho, L. Elo, Claes Ohlsson, P. Kallio, S. Mäkelä, M. V. J. Mustonen, P. Sipilä, Matti Poutanen
American Journal of Pathology - 2018 -
Secreted frizzled-related protein 2 (SFRP2) expression promotes lesion proliferation via canonical WNT signaling and indicates lesion borders in extraovarian
endometriosis
T. Heinosalo, M. Gabriel, L. Kallio, P. Adhikari, K. Huhtinen, T. D. Laajala, E. Kaikkonen, A. Mehmood, P. Suvitie, H. Kujari, T. Aittokallio, A. Perheentupa, Matti Poutanen
Human Reproduction - 2018 -
Inducible Wnt16 inactivation: WNT16 regulates cortical bone thickness in adult
mice.
Claes Ohlsson, Petra Henning, Karin H. Nilsson, Jianyao Wu, Karin L. Gustafsson, Klara Sjögren, Anna E Törnqvist, Antti Koskela, Fu-Ping Zhang, Marie Lagerquist, Matti Poutanen, Juha Tuukkanen, Ulf H Lerner, Sofia Movérare-Skrtic
The Journal of endocrinology - 2018 -
Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer
Xenografts.
Matias Knuuttila, Arfa Mehmood, Riikka Huhtaniemi, Emrah Yatkin, Merja R Häkkinen, Riikka Oksala, Teemu D Laajala, Henrik Ryberg, David J Handelsman, Tero Aittokallio, Seppo Auriola, Claes Ohlsson, Asta Laiho, Laura L Elo, Petra Sipilä, Sari I Mäkelä, Matti Poutanen
The American journal of pathology - 2018 -
Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate
tissue.
Merja R Häkkinen, Teemu Murtola, Raimo Voutilainen, Matti Poutanen, Tero Linnanen, Johanna Koskivuori, Timo Lakka, Jarmo Jääskeläinen, Seppo Auriola
Journal of pharmaceutical and biomedical analysis - 2018 -
Partial thyrocyte-specific Gαs deficiency leads to rapid-onset hypothyroidism, hyperplasia, and papillary thyroid carcinoma-like lesions in
mice.
Konrad Patyra, Holger Jaeschke, Christoffer Löf, Meeri Jännäri, Suvi T Ruohonen, Henriette Undeutsch, Moosa Khalil, Andreina Kero, Matti Poutanen, Jorma Toppari, Min Chen, Lee S Weinstein, Ralf Paschke, Jukka Kero
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2018 -
HSD17B1 expression induces inflammation-aided rupture of mammary gland
myoepithelium.
Päivi Järvensivu, Taija Heinosalo, Janne Hakkarainen, Pauliina Kronqvist, Niina Saarinen, Matti Poutanen
Endocrine-related cancer - 2018 -
Analysis by LC-MS/MS of endogenous steroids from human serum, plasma, endometrium and endometriotic
tissue.
Merja R Häkkinen, Taija Heinosalo, Niina Saarinen, Tero Linnanen, Raimo Voutilainen, Timo Lakka, Jarmo Jääskeläinen, Matti Poutanen, Seppo Auriola
Journal of pharmaceutical and biomedical analysis - 2018 -
Preface.
Matti Poutanen, Manuel Tena-Sempere
Best practice & research. Clinical endocrinology & metabolism - 2018 -
NLRP3 in somatic non-immune cells of rodent and primate
testes.
Lena Walenta, Nina Schmid, J Ullrich Schwarzer, Frank-Michael Köhn, Henryk F Urbanski, Rüdiger Behr, Leena Strauss, Matti Poutanen, Artur Mayerhofer
Reproduction (Cambridge, England) - 2018 -
Insights into the role of androgen receptor in human testicular peritubular
cells.
C Mayer, M Adam, L Walenta, N Schmid, H Heikelä, K Schubert, F Flenkenthaler, K-G Dietrich, S Gruschka, G J Arnold, T Fröhlich, J U Schwarzer, F M Köhn, L Strauss, H Welter, Matti Poutanen, A Mayerhofer
Andrology - 2018 -
Hyperthyroidism and Papillary Thyroid Carcinoma in Thyrotropin Receptor D633H Mutant
Mice.
Holger Jaeschke, Henriette Undeutsch, Konrad Patyra, Christoffer Löf, Markus Eszlinger, Moosa Khalil, Meeri Jännäri, Kristiina Makkonen, Jorma Toppari, Fu-Ping Zhang, Matti Poutanen, Ralf Paschke, Jukka Kero
Thyroid : official journal of the American Thyroid Association - 2018 -
Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin
signaling.
Juan Roa, Alexia Barroso, Francisco Ruiz-Pino, Maria Jesus Vázquez, Patricia Seoane-Collazo, Noelia Martínez-Sanchez, David García-Galiano, Tuncay Ilhan, Rafael Pineda, Silvia León, Maria Manfredi-Lozano, Violeta Heras, Matti Poutanen, Juan M Castellano, Francisco Gaytan, Carlos Diéguez, Leonor Pinilla, Miguel López, Manuel Tena-Sempere
Proceedings of the National Academy of Sciences of the United States of America - 2018 -
Editing activity for eliminating mischarged tRNAs is essential in mammalian
mitochondria.
Taru Hilander, Xiao-Long Zhou, Svetlana Konovalova, Fu-Ping Zhang, Liliya Euro, Dmitri Chilov, Matti Poutanen, Joseph Chihade, En-Duo Wang, Henna Tyynismaa
Nucleic acids research - 2018 -
Hydroxysteroid (17 beta) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in
mice
M. Adam, H. Heikela, C. Sobolewski, D. Portius, J. Maki-Jouppila, A. Mehmood, P. Adhikari, I. Esposito, L. L. Elo, F. P. Zhang, S. T. Ruohonen, L. Strauss, M. Foti, Matti Poutanen
Faseb Journal - 2018 -
The Expression of HSD17B12 Is Associated with COX-2 Expression and Is Increased in High-Grade Epithelial Ovarian
Cancer
H. Kemilainen, K. Huhtinen, A. Auranen, O. Carpen, L. Strauss, Matti Poutanen
Oncology - 2018 -
Maternal expression of the histone demethylase Kdm4a is crucial for pre-implantation
development
A. Sankar, S. M. Kooistra, J. M. Gonzalez, Claes Ohlsson, Matti Poutanen, K. Helin
Development - 2017 -
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male
mice.
Claes Ohlsson, Ann Hammarstedt, Liesbeth Vandenput, Niina Saarinen, Henrik Ryberg, Sara H Windahl, Helen H. Farman, John-Olov Jansson, Sofia Movérare-Skrtic, Ulf Smith, Fu-Ping Zhang, Matti Poutanen, Shahram Hedjazifar, Klara Sjögren
American journal of physiology. Endocrinology and metabolism - 2017 -
Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during
puberty
T. Elo, P. H. Lindfors, Q. Lan, M. Voutilainen, E. Trela, Claes Ohlsson, S. H. Huh, D. M. Ornitz, Matti Poutanen, B. A. Howard, M. L. Mikkola
Scientific Reports - 2017 -
Deleting the mouse Hsd17b1 gene results in a hypomorphic Naglu allele and a phenotype mimicking a lysosomal storage
disease.
Heli Jokela, Janne Hakkarainen, Laura Kätkänaho, Pirjo Pakarinen, Suvi T Ruohonen, Manuel Tena-Sempere, Fu-Ping Zhang, Matti Poutanen
Scientific reports - 2017 -
Matched preclinical designs for improved
translatability.
Tero Aittokallio, Andreas Scherer, Matti Poutanen, Leonard P Freedman
Science translational medicine - 2017 -
In Vivo Expression of miR-32 Induces Proliferation in Prostate
Epithelium.
Leena Latonen, Mauro Scaravilli, Andrew Gillen, Samuli Hartikainen, Fu-Ping Zhang, Pekka Ruusuvuori, Paula Kujala, Matti Poutanen, Tapio Visakorpi
The American journal of pathology - 2017 -
Optimized design and analysis of preclinical intervention studies in
vivo
T. D. Laajala, M. Jumppanen, R. Huhtaniemi, V. Fey, A. Kaur, M. Knuuttila, E. Aho, R. Oksala, J. Westermarck, S. Makela, Matti Poutanen, T. Aittokallio
Scientific Reports - 2016 -
Targeted inactivation of the mouse epididymal beta-defensin 41 alters sperm flagellar beat pattern and zona pellucida
binding
I. Bjorkgren, L. Alvarez, N. Blank, M. Balbach, H. Turunen, T. D. Laajala, J. Toivanen, A. Krutskikh, N. Wahlberg, I. Huhtaniemi, Matti Poutanen, D. Wachten, P. Sipila
Molecular and Cellular Endocrinology - 2016 -
The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of
Fertility.
Heidi Kemiläinen, Marion Adam, Jenni Mäki-Jouppila, Pauliina Damdimopoulou, Anastasios E Damdimopoulos, Juha Kere, Outi Hovatta, Teemu D Laajala, Tero Aittokallio, Jerzy Adamski, Henrik Ryberg, Claes Ohlsson, Leena Strauss, Matti Poutanen
Endocrinology - 2016 -
Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male
mouse
A. P. Vehmas, M. Adam, T. D. Laajala, G. Kastenmuller, C. Prehn, J. Rozman, Claes Ohlsson, H. Fuchs, M. H. de Angelis, V. Gailus-Durner, L. L. Elo, T. Aittokallio, J. Adamski, G. Corthals, Matti Poutanen, L. Strauss
Journal of Proteomics - 2016 -
Efficient Light-Induced Phase Transitions in Halogen-Bonded Liquid
Crystals.
Francisco Fernandez-Palacio, Matti Poutanen, Marco Saccone, Antti Siiskonen, Giancarlo Terraneo, Giuseppe Resnati, Olli Ikkala, Pierangelo Metrangolo, Arri Priimagi
Chemistry of materials : a publication of the American Chemical Society - 2016 -
Sterile inflammation as a factor in human male infertility: Involvement of Toll like receptor 2, biglycan and peritubular
cells.
C Mayer, M Adam, L Glashauser, K Dietrich, J U Schwarzer, F-M Köhn, L Strauss, H Welter, Matti Poutanen, A Mayerhofer
Scientific reports - 2016 -
A Nanoparticle-Lectin Immunoassay Improves Discrimination of Serum CA125 from Malignant and Benign
Sources.
Kamlesh Gidwani, Kaisa Huhtinen, Henna Kekki, Sandra van Vliet, Johanna Hynninen, Niina Koivuviita, Antti Perheentupa, Matti Poutanen, Annika Auranen, Seija Grenman, Urpo Lamminmäki, Olli Carpen, Yvette van Kooyk, Kim Pettersson
Clinical chemistry - 2016 -
Hyperprolactinemia induced by hCG leads to metabolic disturbances in female
mice.
Laura D Ratner, Guillermina Stevens, Maria Marta Bonaventura, Victoria A Lux-Lantos, Matti Poutanen, Ricardo S Calandra, Ilpo T Huhtaniemi, Susana B Rulli
The Journal of endocrinology - 2016 -
From pure compounds to complex exposure: Effects of dietary cadmium and lignans on estrogen, epidermal growth factor receptor, and mitogen activated protein kinase signaling in
vivo.
Imran Ali, Teija Hurmerinta, Tarja Nurmi, Marika Berglund, Joelle Rüegg, Matti Poutanen, Krister Halldin, Sari Mäkelä, Pauliina Damdimopoulou
Toxicology letters - 2016 -
Stress-activated miR-21/miR-21* in hepatocytes promotes lipid and glucose metabolic disorders associated with high-fat diet
consumption.
Nicolas Calo, Pierluigi Ramadori, Cyril Sobolewski, Yannick Romero, Christine Maeder, Margot Fournier, Pia Rantakari, Fu-Ping Zhang, Matti Poutanen, Jean-François Dufour, Bostjan Humar, Serge Nef, Michelangelo Foti
Gut - 2016 -
Fam3c modulates osteogenic cell differentiation and affects bone volume and cortical bone mineral
density.
Jorma A Määttä, Ameya Bendre, Mervi Laanti, Kalman G Büki, Pia Rantakari, Päivi Tervola, Johanna Saarimäki, Matti Poutanen, Pirkko Härkönen, Kalervo Väänänen
BoneKEy reports - 2016 -
The bone-sparing effects of estrogen and WNT16 are independent of each
other
Sofia Movérare-Skrtic, Jianyao Wu, Petra Henning, Karin L. Gustafsson, Klara Sjögren, Sara H Windahl, A. Koskela, J. Tuukkanen, Anna E Börjesson, Marie K Lagerquist, Ulf H Lerner, F.P. Zhang, J.Å. Gustafsson, Matti Poutanen, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2015 -
Autocrine Action of IGF2 Regulates Adult β-Cell Mass and
Function.
Honey Modi, Cecile Jacovetti, David Tarussio, Salima Metref, Ole D Madsen, Fu-Ping Zhang, Pia Rantakari, Matti Poutanen, Serge Nef, Tracy Gorman, Romano Regazzi, Bernard Thorens
Diabetes - 2015 -
Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different
Phenotypes.
Outi Sareila, Cecilia Hagert, Pia Rantakari, Matti Poutanen, Rikard Holmdahl
PloS one - 2015 -
Thyrocyte-specific Dicer1 deficiency alters thyroid follicular organization and prevents goiter
development.
H Undeutsch, C Löf, P Pakarinen, Matti Poutanen, J Kero
Endocrinology - 2015 -
HSD17B1 expression enhances estrogen signaling stimulated by the low active estrone, evidenced by an estrogen responsive element-driven reporter gene in
vivo.
Päivi Järvensivu, Taija Saloniemi-Heinonen, Michael Awosanya, Pasi Koskimies, Niina Saarinen, Matti Poutanen
Chemico-biological interactions - 2015 -
Optimization of Statistical Methods Impact on Quantitative Proteomics
Data.
Anna Pursiheimo, Anni P Vehmas, Saira Afzal, Tomi Suomi, Thaman Chand, Leena Strauss, Matti Poutanen, Anne Rokka, Garry L Corthals, Laura L Elo
Journal of proteome research - 2015 -
Hydroxysteroid (17 beta)-dehydrogenase 1-deficient female mice present with normal puberty onset but are severely subfertile due to a defect in luteinization and progesterone
production
J. Hakkarainen, H. Jokela, P. Pakarinen, H. Heikela, L. Katkanaho, Liesbeth Vandenput, Claes Ohlsson, F. P. Zhang, Matti Poutanen
Faseb Journal - 2015 -
Measurement of a comprehensive sex steroid profile in rodent serum by high-sensitive gas chromatography-tandem mass
spectrometry.
Maria E. Nilsson, Liesbeth Vandenput, Åsa Tivesten, Anna-Karin Norlén, Marie K Lagerquist, Sara H Windahl, Anna E Börjesson, Helen H. Farman, Matti Poutanen, Anna Benrick, Manuel Maliqueo, Elisabet Stener-Victorin, Henrik Ryberg, Claes Ohlsson
Endocrinology - 2015 -
Imbalanced lipid homeostasis in the conditional Dicer1 knockout mouse epididymis causes instability of the sperm
membrane.
Ida Björkgren, Helena Gylling, Heikki Turunen, Ilpo Huhtaniemi, Leena Strauss, Matti Poutanen, Petra Sipilä
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2015 -
Elevated hypothalamic aromatization at the onset of precocious puberty in transgenic female mice hypersecreting human chorionic gonadotropin: effect of
androgens.
Betina Gonzalez, Laura D Ratner, María J Scerbo, Noelia P Di Giorgio, Matti Poutanen, Ilpo T Huhtaniemi, Ricardo S Calandra, Victoria A R Lux-Lantos, María J Cambiasso, Susana B Rulli
Molecular and cellular endocrinology - 2014 -
Human testicular peritubular cells host putative stem Leydig cells with steroidogenic
capacity.
Luise Landreh, Katrin Spinnler, Kerstin Schubert, Merja R Häkkinen, Seppo Auriola, Matti Poutanen, Olle Söder, Konstantin Svechnikov, Artur Mayerhofer
The Journal of clinical endocrinology and metabolism - 2014 -
ErbB4, a receptor tyrosine kinase, coordinates organization of the seminiferous tubules in the developing
testis.
Florence Naillat, Ville Veikkolainen, Ilkka Miinalainen, Petra Sipilä, Matti Poutanen, Klaus Elenius, Seppo J Vainio
Molecular endocrinology (Baltimore, Md.) - 2014 -
Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility
fractures.
Sofia Movérare-Skrtic, Petra Henning, Xianwen Liu, Kenichi Nagano, Hiroaki Saito, Anna E Börjesson, Klara Sjögren, Sara H Windahl, Helen H. Farman, Bert Kindlund, Cecilia Engdahl, Antti Koskela, Fu-Ping Zhang, Emma E Eriksson, Farasat Zaman, Ann Hammarstedt, Hanna Isaksson, Marta Bally, Ali Kassem, Catharina Lindholm, Olof Sandberg, Per Aspenberg, Lars Sävendahl, Jian Q Feng, Jan Tuckermann, Juha Tuukkanen, Matti Poutanen, Roland Baron, Ulf H Lerner, Francesca Gori, Claes Ohlsson
Nature Medicine - 2014 -
Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis
lesions.
Kaisa Huhtinen, Taija Saloniemi-Heinonen, Pekka Keski-Rahkonen, Reena Desai, Daniel Laajala, Mia Ståhle, Merja R Häkkinen, Michael Awosanya, Pia Suvitie, Harry Kujari, Tero Aittokallio, David J Handelsman, Seppo Auriola, Antti Perheentupa, Matti Poutanen
The Journal of clinical endocrinology and metabolism - 2014 -
Ovarian Endometriosis Signatures Established through Discovery and Directed Mass Spectrometry
Analysis
A. P. Vehmas, D. Muth-Pawlak, K. Huhtinen, T. Saloniemi-Heinonen, K. Jaakkola, T. D. Laajala, H. Kaprio, P. A. Suvitie, T. Aittokallio, H. Siitari, A. Perheentupa, Matti Poutanen, G. L. Corthals
Journal of Proteome Research - 2014 -
Castration Induces Up-Regulation of Intratumoral Androgen Biosynthesis and Androgen Receptor Expression in an Orthotopic VCaP Human Prostate Cancer Xenograft
Model
M. Knuuttila, E. Yatkin, J. Kallio, S. Savolainen, T. D. Laajala, T. Aittokallio, R. Oksala, M. Hakkinen, P. Keski-Rahkonen, S. Auriola, Matti Poutanen, Sari Mäkelä
American Journal of Pathology - 2014 -
Inactivation of estrogen receptor α in bone-forming cells induces bone loss in female
mice.
Jorma A Määttä, Kalman G Büki, Guoliang Gu, Maria H Alanne, Jukka Vääräniemi, Heidi Liljenbäck, Matti Poutanen, Pirkko Härkönen, Kalervo Väänänen
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2013 -
Inactivation of the androgen receptor in bone-forming cells leads to trabecular bone loss in adult female
mice.
Jorma A Määttä, Kalman G Büki, Kaisa K Ivaska, Vappu Nieminen-Pihala, Teresa D Elo, Tiina Kähkönen, Matti Poutanen, Pirkko Härkönen, Kalervo Väänänen
BoneKEy reports - 2013 -
LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure
photoionization.
Pekka Keski-Rahkonen, Kaisa Huhtinen, Reena Desai, D Tim Harwood, David J Handelsman, Matti Poutanen, Seppo Auriola
Journal of mass spectrometry : JMS - 2013 -
The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic
signals.
Jaya Nautiyal, Jennifer H Steel, Meritxell Rosell Mane, Olayiwola Oduwole, Ariel Poliandri, Xanthippi Alexi, Nicholas Wood, Matti Poutanen, Wilbert Zwart, John Stingl, Malcolm G Parker
Development (Cambridge, England) - 2013 -
Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue
specimens.
Leena Strauss, Pia Rantakari, Klara Sjögren, Anu Salminen, Eve Lauren, Jenny Kallio, Pauliina Damdimopoulou, Minna Boström, Peter J Boström, Pirjo Pakarinen, Fuping Zhang, Paula Kujala, Claes Ohlsson, Sari Mäkelä, Matti Poutanen
The FASEB Journal - 2013 -
Short-term pharmacological suppression of the hyperprolactinemia of infertile hCG-overproducing female mice persistently restores their
fertility.
Laura D Ratner, Betina Gonzalez, Petteri Ahtiainen, Noelia P Di Giorgio, Matti Poutanen, Ricardo S Calandra, Ilpo T Huhtaniemi, Susana B Rulli
Endocrinology - 2012 -
Loss of Bmyc results in increased apoptosis associated with upregulation of Myc expression in juvenile murine
testis.
Heikki T Turunen, Petra Sipilä, Leena Strauss, Ida Björkgren, Ilpo Huhtaniemi, Matti Poutanen
Reproduction (Cambridge, England) - 2012 -
Epididymal protein Rnase10 is required for post-testicular sperm maturation and male
fertility.
Anton Krutskikh, Ariel Poliandri, Victoria Cabrera-Sharp, Jean Louis Dacheux, Matti Poutanen, Ilpo Huhtaniemi
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2012 -
Dicer1 ablation in the mouse epididymis causes dedifferentiation of the epithelium and imbalance in sex steroid
signaling.
Ida Björkgren, Lauri Saastamoinen, Anton Krutskikh, Ilpo Huhtaniemi, Matti Poutanen, Petra Sipilä
PloS one - 2012 -
Interactions between inflammatory signals and the progesterone receptor in regulating gene expression in pregnant human uterine
myocytes
Yun Lee, Suren R Sooranna, Vasso Terzidou, Mark Christian, Jan Brosens, Kaisa Huhtinen, Matti Poutanen, Geraint Barton, Mark R Johnson, Phillip R Bennett
Journal of cellular and molecular medicine - 2012 -
Serum HE4 concentration is not dependent on menstrual cycle or hormonal treatment among endometriosis patients and healthy premenopausal
women.
M Hallamaa, P Suvitie, K Huhtinen, J Matomäki, Matti Poutanen, A Perheentupa
Gynecologic oncology - 2012 -
Fibroblast growth factor 8b causes progressive stromal and epithelial changes in the epididymis and degeneration of the seminiferous epithelium in the testis of transgenic
mice.
Teresa Elo, Petra Sipilä, Eeva Valve, Paula Kujala, Jorma Toppari, Matti Poutanen, Pirkko Härkönen
Biology of reproduction - 2012 -
High levels of the extracellular matrix proteoglycan decorin are associated with inhibition of testicular
function.
M Adam, H F Urbanski, V T Garyfallou, U Welsch, F M Köhn, J Ullrich Schwarzer, L Strauss, Matti Poutanen, A Mayerhofer
International journal of andrology - 2012 -
Comparison of liquid chromatography-microchip/mass spectrometry to conventional liquid chromatography-mass spectrometry for the analysis of
steroids.
Linda Ahonen, Pekka Keski-Rahkonen, Taija Saarelainen, Jenni Paviala, Raimo A Ketola, Seppo Auriola, Matti Poutanen, Risto Kostianen
Analytica chimica acta - 2012 -
Understanding the diversity of sex steroid
action.
Matti Poutanen
The Journal of endocrinology - 2012 -
The diversity of sex steroid action: novel functions of hydroxysteroid (17β) dehydrogenases as revealed by genetically modified mouse
models.
Taija Saloniemi, Heli Jokela, Leena Strauss, Pirjo Pakarinen, Matti Poutanen
The Journal of endocrinology - 2012 -
Estrogen biosynthesis and signaling in
endometriosis
Kaisa Huhtinen, Mia Ståhle, Antti Perheentupa, Matti Poutanen
Molecular and cellular endocrinology - 2012 -
Loss of cysteine-rich secretory protein 4 (Crisp4) leads to deficiency in sperm-zona pellucida interaction in
mice.
Heikki T Turunen, Petra Sipilä, Anton Krutskikh, Jussi Toivanen, Harri Mankonen, Veera Hämäläinen, Ida Björkgren, Ilpo Huhtaniemi, Matti Poutanen
Biology of reproduction - 2012 -
Endometrial and Endometriotic Concentrations of Estrone and Estradiol Are Determined by Local Metabolism Rather than Circulating
Levels.
Kaisa Huhtinen, Reena Desai, Mia Ståhle, Anu Salminen, David J Handelsman, Antti Perheentupa, Matti Poutanen
The Journal of clinical endocrinology and metabolism - 2012 -
Improved statistical modeling of tumor growth and treatment effect in preclinical animal studies with highly heterogeneous responses in
vivo.
Teemu D Laajala, Jukka Corander, Niina M Saarinen, Katja Mäkelä, Saija Savolainen, Mari I Suominen, Esa Alhoniemi, Sari Mäkelä, Matti Poutanen, Tero Aittokallio
Clinical cancer research : an official journal of the American Association for Cancer Research - 2012 -
Endogenously elevated androgens alter the developmental programming of the hypothalamic-pituitary axis in male
mice.
Betina Gonzalez, Laura D Ratner, Noelia P Di Giorgio, Matti Poutanen, Ilpo T Huhtaniemi, Ricardo S Calandra, Victoria A R Lux-Lantos, Susana B Rulli
Molecular and cellular endocrinology - 2011 -
Targeted inactivation of the androgen receptor gene in murine proximal epididymis causes epithelial hypotrophy and obstructive
azoospermia.
Anton Krutskikh, Karel De Gendt, Victoria Sharp, Guido Verhoeven, Matti Poutanen, Ilpo Huhtaniemi
Endocrinology - 2011 -
Fast and sensitive liquid chromatography-mass spectrometry assay for seven androgenic and progestagenic steroids in human
serum.
Pekka Keski-Rahkonen, Kaisa Huhtinen, Matti Poutanen, Seppo Auriola
The Journal of steroid biochemistry and molecular biology - 2011 -
A single dose of enterolactone activates estrogen signaling and regulates expression of circadian clock genes in
mice.
Pauliina Damdimopoulou, Tarja Nurmi, Anu Salminen, Anastasios E Damdimopoulos, Maria Kotka, Paul van der Saag, Leena Strauss, Matti Poutanen, Ingemar Pongratz, Sari Mäkelä
The Journal of nutrition - 2011 -
ERβ1 represses FOXM1 expression through targeting ERα to control cell proliferation in breast
cancer.
Yoshiya Horimoto, Johan Hartman, Julie Millour, Steven Pollock, Yolanda Olmos, Ka-Kei Ho, R Charles Coombes, Matti Poutanen, Sari I Mäkelä, Mona El-Bahrawy, Valerie Speirs, Eric W-F Lam
The American journal of pathology - 2011 -
Regional expression of androgen receptor coregulators and androgen action in the mouse
epididymis.
Petra Sipilä, Anton Krutskikh, Dwi Ari Pujianto, Matti Poutanen, Ilpo Huhtaniemi
Journal of andrology - 2011 -
Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor
signaling.
M Adam, J U Schwarzer, F M Köhn, L Strauss, Matti Poutanen, A Mayerhofer
Human reproduction (Oxford, England) - 2011 -
Down-regulation of the histone methyltransferase EZH2 contributes to the epigenetic programming of decidualizing human endometrial stromal
cells.
Giulia Grimaldi, Mark Christian, Jennifer H Steel, Patrick Henriet, Matti Poutanen, Jan J Brosens
Molecular endocrinology (Baltimore, Md.) - 2011 -
Members of the murine Pate family are predominantly expressed in the epididymis in a segment-specific fashion and regulated by androgens and other testicular
factors.
Heikki T Turunen, Petra Sipilä, Dwi Ari Pujianto, Anastasios E Damdimopoulos, Ida Björkgren, Ilpo Huhtaniemi, Matti Poutanen
Reproductive biology and endocrinology : RB&E - 2011