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- Ulrika Islander
Ulrika Islander
Forskare
Avd för reumatologi och inflammationsforskningOm Ulrika Islander
Titel: Med Dr, Docent
Ulrika Islander erhöll 2002 en Magisterexamen i molekylärbiologi med fokus på immunologi från Lunds universitet. Hon disputerade 2007 vid Göteborgs universitet i ämnet reumatologi, och 2015 blev hon Docent i immunologi vid Sahlgrenska akademin. Under 2017–2018 arbetade hon som gästforskare vid Institute of Immunobiology i St Gallen, Schweiz, i syfte att lära sig mer om forskning rörande stromacellers påverkan på immunförsvarets funktioner vid virusinfektion. Utöver sin tjänst som Forskare och gruppledare vid Göteborgs universitet är hon även anställd på deltid som Gästforskare vid Chalmers tekniska högskola.
Forskningsintressen
Könshormoner har stora effekter på immunförsvaret vilket kan påverka risken att utveckla vissa sjukdomar. Kvinnor löper högre risk att drabbas av autoimmuna sjukdomar, men blir ofta mindre sjuka än män vid infektionssjukdomar. Mekanismerna bakom könsskillnaderna vid dessa tillstånd är fortfarande oklara och det övergripande syftet med Ulrika Islanders forskning är att identifiera hur östrogen påverkar immunförsvarets cellulära och molekylära processer vid autoimmunitet och infektion. Identifiering av dessa mekanismer kan ge möjlighet till utveckling av nya behandlingar för flera östrogenkänsliga tillstånd.
Pågående projekt i gruppen innefattar:
- Att identifiera mekanismer som ligger till grund för de motsatta effekterna av östrogen på immunrespons vid reumatoid artrit (RA) och systemisk lupus erythematous (SLE).
- Att påvisa om de skyddande effekterna av östrogen på skelettet vid RA och SLE medieras via stromaceller i benmärg.
- Att definiera betydelsen av stromaceller i primära och sekundära lymfoida organ för östrogens påverkan på immunförsvarets funktion.
- Att identifiera immunologiska mekanismer involverade i de skyddande effekterna av östrogen vid infektion med influensavirus.
Projekten innefattar både preklinisk forskning (in vivo och in vitro), samt kliniska studier i samarbete med läkare vid Sahlgrenska universitetssjukhuset.
Gruppmedlemmar:
- Julia Scheffler, Med Dr, forskare
- Aidan Barrett, MSc, doktorand
Alumni:
- Piotr Humeniuk, postdok, 2020–2022
- Alicia Del Carpio Pons, forskningsassistent, 2020–2022
- Carmen Corciulo, Marie Sklodowska-Curie postdok, 2019–2023
- Louise Henningsson, forskningsingenjör, 2019
- Christina Drevinge, postdok, 2018–2022
- Julia Scheffler, postdok, 2017–2020
- Catalin Koro-Arvidsson, postdok, 2016–2017
- Jauquline Nordqvist, doktorand, 2015–2021
- Angelina Bernardi, doktorand, 2013–2015
- Louise Grahnemo, postdok, 2012–2014
- Annica Andersson, doktorand, 2011–2016
- Alexandra Stubelius, doktorand, 2008–2014
Undervisning
- 2024-2025: Kursledare kursen "Handledning i Forskarutbildning" vid Enheten för Pedagogisk utveckling och Interaktivt Lärande (PIL201 SA).
- 2016-2022: Kursledare för doktorandkursen ”Immunologiska och molekylärbiologiska laboratorietekniker - 5hp (SM00034).
Uppdrag
- 2021-2122: Ledamot i Fasta betygskollegiet, Institutionen för medicin
- 2018-2024: Ledamot i Institutionsrådet, Institutionen för medicin
- 2015- : Ledamot i Ledningsrådet, Avd. för reumatologi och inflammationsforskning
- 2015- : Ledamot i Forskarutbildningsutskottet, Institutionen för medicin
Några finansiärer
- ALF vg-region
- Emil och Wera Cornells vetenskapliga stiftelse
- Hasselbladstiftelsen
- IngaBritt och Arne Lundbergs stiftelse
- Marie Sklodowska-Curie Action
- Novo Nordiskfonden
- Professor Nanna Swartz stiftelse
- Reumatikerfonden
- Stiftelsen Konung Gustaf V:s 80-års fond
- Vetenskapsrådet
Nyckelpublikationer
Profiling of innate and adaptive immune cells during influenza virus infection reveals sex bias in invariant natural killer T (iNKT) cells
Humeniuk P, Barrett A, Axelsson H, Corciulo C, Drevinge C, Del Carpio Pons AM, Angeletti D, Scheffler JM, Islander U
Immunity, Inflammation and Disease. 2023 Mar, doi.org/10.1002/iid3.837
ERa signaling in a subset of CXCL12-abundant reticular cells regulates trabecular bone in mice
Scheffler JM, Gustafsson KL, Barrett A, Corciulo C, Drevinge C, Del Carpio Pons AM, Humeniuk P, Engdahl C, Gustafsson J-Å, Ohlsson C, Carlsten H, Lagerquist MK, Islander U
JBMR plus. 2022 May 30. doi.org/10.1002/jbm4.10657
A tissue-selective estrogen complex as treatment of osteoporosis in experimental lupus
Nordqvist J, Engdahl C, Scheffler JM, Gupta P, Gustafsson KL, Lagerquist MK, Carlsten H, Islander U
Lupus. 2022 Feb;31(2):143-154. doi: 10.1177/09612033211067984.
Intermediate monocytes correlate with CXCR3+ Th17 cells but not with bone characteristics in untreated early rheumatoid arthritis
Drevinge C, Scheffler JM, Karo-Arvidsson C, Sundh D, Carlsten H, Gjertsson I, Lindholm C, Lorentzon M, Rudin A, Hultgard-Ekwall AK, Islander U
PLoS One. 2021 Mar 26;16(3)
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8+ T cells
Perez-Shibayama C, Islander U, Lütge M, Cheng HW, Onder L, Ring S, de Martin A, Novkovic M, Colston J, Gil-Cruz C, Ludewig B
Science Immunology. 2020 Sep 11;5(51):eabb7066.
Läs mer
Gruppledare för forskargruppen “Kvinnor och inflammation”
https://www.gu.se/forskning/kvinnor-och-inflammation
Gruppledare vid SciLifeLab
https://www.scilifelab.se/researchers/ulrika-islander/
Akademiliv:
https://akademiliv.se/2018/10/53196/
https://akademiliv.se/2016/11/36287/
https://akademiliv.se/2016/04/33209/
IngaBritt och Arne Lundbergs stiftelse:
-
Circulating Baseline CXCR3+Th2 and Th17 Cell Proportions Correlate With Trabecular Bone Loss After 48 Weeks of Biological Treatment in Early Rheumatoid
Arthritis
Julia Scheffler, Christina Drevinge, Catharina Lindholm, Inger Gjertsson, Kristina Lend, Merete Lund Hetland, Mikkel Ostergaard, Till Uhlig, Marte Schrumpf Heiberg, Espen A. Haavardsholm, Michael T. Nurmohamed, Jon Lampa, Tuulikki Sokka-Isler, Dan Nordstrom, Kim Horslev-Petersen, Bjorn Gudbjornsson, Gerdur Grondal, Ronald van Vollenhoven, Hans Carlsten, Mattias Lorentzon, Anna-Karin Hultgård Ekwall, Anna Rudin, Ulrika Islander
ACR OPEN RHEUMATOLOGY - 2024 -
Role of estrogen signaling in fibroblastic reticular cells for innate and adaptive immune responses in antigen-induced
arthritis
Aidan Barrett, Karin Horkeby, Carmen Corciulo, Hans Carlsten, Marie K Lagerquist, Julia Scheffler, Ulrika Islander
IMMUNOLOGY AND CELL BIOLOGY - 2024 -
Treatment with a tissue-selective oestrogen complex does not affect disease pathology but reduces pre-BI cells in lupus-prone
mice.
Christina Drevinge, Julia Scheffler, Jauqueline Nordqvist, Cecilia Engdahl, Hans Carlsten, Ulrika Islander
Scandinavian journal of rheumatology - 2024 -
The Pseudomonas aeruginosa lectin LecB modulates intracellular reactive oxygen species production in human
neutrophils
F. P. S. Klose, Agnes Dahlstrand Rudin, Linda Bergqvist, Julia Scheffler, Katarina Jönsson, Ulrika Islander, Anna Karlsson-Bengtsson, Johan Bylund, V. Venkatakrishnan
European Journal of Immunology - 2024 -
Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway
inflammation
Aidan Barrett, Piotr Humeniuk, Christina Drevinge, Carmen Corciulo, Julie Weidner, Madeleine Rådinger, Hans Carlsten, Julia M. Scheffler, Ulrika Islander
Immunobiology - 2023 -
Sex and gender in infection and immunity: addressing the bottlenecks from basic science to public health and clinical
applications
C. Pasin, C. R. Consiglio, J. S. Huisman, A. M. G. de Lange, H. Peckham, E. Vallejo-Yaguee, I. A. Abela, Ulrika Islander, N. Neuner-Jehle, M. Pujantell, O. Roth, M. Schirmer, B. Tepekule, M. Zeeb, A. Hachfeld, K. Aebi-Popp, R. D. Kouyos, S. Bonhoeffer
Royal Society Open Science - 2023 -
Profiling of innate and adaptive immune cells during influenza virus infection reveals sex bias in invariant natural killer T (iNKT)
cells
Piotr Humeniuk, Aidan Barrett, Hannes Axelsson, Carmen Corciulo, Christina Drevinge, Alicia M. del Carpio Pons, Davide Angeletti, Julia M. Scheffler, Ulrika Islander
Immunity, Inflammation and Disease - 2023 -
Physiological levels of estradiol limit murine osteoarthritis
progression
Carmen Corciulo, Julia M. Scheffler, Piotr Humeniuk, Alicia M. del Carpio Pons, Alexandra Stubelius, U. Von Mentzer, Christina Drevinge, Aidan Barrett, Sofia Wüstenhagen, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
Journal of Endocrinology - 2022 -
A tissue-specific role of membrane-initiated ERα signaling for the effects of
SERMs
Karin L. Gustafsson, Sofia Movérare-Skrtic, Helen H. Farman, Cecilia Engdahl, Petra Henning, Karin H. Nilsson, Julia M. Scheffler, Edina Sehic, Ulrika Islander, E. Levin, Claes Ohlsson, Marie K Lagerquist
Journal of Endocrinology - 2022 -
A tissue-selective estrogen complex as treatment of osteoporosis in experimental
lupus
Jauqueline Nordqvist, Cecilia Engdahl, Julia M. Scheffler, Priti Gupta, Karin L. Gustafsson, Marie K Lagerquist, Hans Carlsten, Ulrika Islander
Lupus - 2022 -
Reduction of Mature B Cells and Immunoglobulins Results in Increased Trabecular
Bone
Marie K Lagerquist, P. Gupta, E. Sehic, Karin L Horkeby, Julia M. Scheffler, Jauqueline Nordqvist, Lina Lawenius, Ulrika Islander, Carmen Corciulo, Petra Henning, Hans Carlsten, Cecilia Engdahl
Jbmr Plus - 2022 -
ER alpha Signaling in a Subset of CXCL12-Abundant Reticular Cells Regulates Trabecular Bone in
Mice
Julia M. Scheffler, Karin L. Gustafsson, Aidan Barrett, Carmen Corciulo, Christina Drevinge, Alicia M. del Carpio Pons, Piotr Humeniuk, Cecilia Engdahl, J. A. Gustafsson, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist, Ulrika Islander
JBMR Plus - 2022 -
Mild stimulatory effect of a probiotic mix on bone mass when treatment is initiated 1.5 weeks after ovariectomy in
mice
Claes Ohlsson, Lina Lawenius, Annica Andersson, Karin L. Gustafsson, Jianyao Wu, Marie Lagerquist, Sofia Moverare-Skrtic, Ulrika Islander, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2021 -
Intermediate monocytes correlate with CXCR3(+) Th17 cells but not with bone characteristics in untreated early rheumatoid
arthritis
Christina Drevinge, Julia M. Scheffler, Catalin Koro-Arvidsson, Daniel Sundh, Hans Carlsten, Inger Gjertsson, Catharina Lindholm, Mattias Lorentzon, Anna Rudin, Anna-Karin Hultgård Ekwall, Ulrika Islander
Plos One - 2021 -
Pulsed administration for physiological estrogen replacement in
mice
Carmen Corciulo, Julia M. Scheffler, Karin L. Gustafsson, Christina Drevinge, Piotr Humeniuk, Alicia M. del Carpio Pons, Matti Poutanen, Claes Ohlsson, Marie K Lagerquist, Ulrika Islander
F1000Research - 2021 -
Pasteurized Akkermansia muciniphila protects from fat mass gain but not from bone
loss
Lina Lawenius, Julia M. Scheffler, Karin L. Gustafsson, Petra Henning, Karin H. Nilsson, Hannah Colldén, Ulrika Islander, H. Plovier, P. D. Cani, W. M. de Vos, Claes Ohlsson, Klara Sjögren
American Journal of Physiology-Endocrinology and Metabolism - 2020 -
Type I interferon signaling in fibroblastic reticular cells prevents exhaustive activation of antiviral CD8+ T
cells.
Christian Perez-Shibayama, Ulrika Islander, Mechthild Lütge, Hung-Wei Cheng, Lucas Onder, Sandra S Ring, Angelina De Martin, Mario Novkovic, Julia Colston, Cristina Gil-Cruz, Burkhard Ludewig
Science immunology - 2020 -
Phosphorylation site S122 in estrogen receptor α has a tissue-dependent role in female
mice
Claes Ohlsson, Karin L. Gustafsson, Helen H. Farman, Petra Henning, Vikte Lionikaite, Sofia Movérare-Skrtic, Klara Sjögren, Anna E Törnqvist, Annica Andersson, Ulrika Islander, Angelina I Bernardi, Matti Poutanen, Pierre Chambon, Marie K Lagerquist
FASEB Journal - 2020 -
Interleukin 17A: a Janus-faced regulator of
osteoporosis
Julia M. Scheffler, Louise Grahnemo, Cecilia Engdahl, Christina Drevinge, Karin L. Gustafsson, Carmen Corciulo, Lina Lawenius, Y. Iwakura, Klara Sjögren, Marie Lagerquist, Hans Carlsten, Claes Ohlsson, Ulrika Islander
Scientific Reports - 2020 -
Osteoporosis in a murine model of postmenopausal
lupus
Jauqueline Nordqvist, Marie K Lagerquist, Louise Grahnemo, A. Koskela, Ulrika Islander, Hans Carlsten
Lupus - 2020 -
ER alpha expression in T lymphocytes is dispensable for estrogenic effects in
bone
Karin L. Gustafsson, Karin H. Nilsson, Helen H. Farman, Vikte Lionikaite, Petra Henning, Jianyao Wu, Sara H Windahl, Ulrika Islander, Sofia Moverare-Skrtic, Klara Sjögren, Hans Carlsten, Claes Ohlsson, Marie Lagerquist
Journal of Endocrinology - 2018 -
Roles of activating functions 1 and 2 of estrogen receptor α in
lymphopoiesis.
Annica Andersson, Sofia Movérare-Skrtic, Angelina I Bernardi, Helen H. Farman, Pierre Chambon, Cecilia Engdahl, Marie Lagerquist, Sara H Windahl, Hans Carlsten, Claes Ohlsson, Ulrika Islander
The Journal of endocrinology - 2018 -
Ovarian hormones in innate
inflammation
Alexandra Stubelius, Annica Andersson, Ulrika Islander, Hans Carlsten
Immunobiology - 2017 -
Effects of a tissue-selective estrogen complex on B lymphopoiesis and B cell
function
Jauqueline Nordqvist, Angelina I Bernardi, Ulrika Islander, Hans Carlsten
Immunobiology - 2017 -
Selective oestrogen receptor modulators lasofoxifene and bazedoxifene inhibit joint inflammation and osteoporosis in ovariectomised mice with collagen-induced
arthritis.
Annica Andersson, Angelina I Bernardi, Alexandra Stubelius, Merja Nurkkala Karlsson, Claes Ohlsson, Hans Carlsten, Ulrika Islander
Rheumatology (Oxford, England) - 2016 -
Suppression of Experimental Arthritis and Associated Bone Loss by a Tissue-Selective Estrogen
Complex.
Annica Andersson, Angelina I Bernardi, Merja Nurkkala Karlsson, Alexandra Stubelius, Louise Grahnemo, Claes Ohlsson, Hans Carlsten, Ulrika Islander
Endocrinology - 2016 -
Enzalutamide Reduces the Bone Mass in the Axial but not the Appendicular Skeleton in Male
Mice.
Jianyao Wu, Sofia Movérare-Skrtic, Anna E Börjesson, Marie K Lagerquist, Klara Sjögren, Sara H Windahl, Antti Koskela, Louise Grahnemo, Ulrika Islander, Anna S K Wilhelmson, Åsa Tivesten, Juha Tuukkanen, Claes Ohlsson
Endocrinology - 2016 -
Ncf1 affects osteoclast formation but is not critical for postmenopausal bone
loss
Alexandra Stubelius, Annica Andersson, R. Holmdahl, Claes Ohlsson, Ulrika Islander, Hans Carlsten
BMC Musculoskeletal Disorders - 2016 -
IL-17-producing γδT cells are regulated by estrogen during development of experimental
arthritis.
Annica Andersson, Louise Grahnemo, Cecilia Engdahl, Alexandra Stubelius, Marie K Lagerquist, Hans Carlsten, Ulrika Islander
Clinical immunology (Orlando, Fla.) - 2015 -
Trabecular bone loss in collagen antibody-induced
arthritis
Louise Grahnemo, Annica Andersson, Merja Nurkkala Karlsson, Alexandra Stubelius, Marie K Lagerquist, Mattias Svensson, Claes Ohlsson, Hans Carlsten, Ulrika Islander
Arthritis Research & Therapy - 2015 -
Selective estrogen receptor modulators in T cell development and T cell dependent
inflammation
Angelina I Bernardi, Annica Andersson, Alexandra Stubelius, Louise Grahnemo, Hans Carlsten, Ulrika Islander
Immunobiology - 2015 -
Estrogen regulates T helper 17 phenotype and localization in experimental autoimmune
arthritis
Annica Andersson, Alexandra Stubelius, Merja Nurkkala Karlsson, Cecilia Engdahl, Malin Erlandsson, Louise Grahnemo, Marie K Lagerquist, Ulrika Islander
Arthritis Research & Therapy - 2015 -
Possible role of lymphocytes in glucocorticoid-induced increase in trabecular bone mineral
density.
Louise Grahnemo, Caroline Jochems, Annica Andersson, Cecilia Engdahl, Claes Ohlsson, Ulrika Islander, Hans Carlsten
The Journal of endocrinology - 2015 -
Effects of lasofoxifene and bazedoxifene on B cell development and
function.
Angelina I Bernardi, Annica Andersson, Louise Grahnemo, Merja Nurkkala Karlsson, Claes Ohlsson, Hans Carlsten, Ulrika Islander
Immunity, inflammation and disease - 2014 -
alpha 7 Nicotinic Acetylcholine Receptor Is Expressed in Human Atherosclerosis and Inhibits Disease in Mice-Brief
Report
Maria E Johansson, Marcus A Ulleryd, Angelina I Bernardi, A. M. Lundberg, Annica Andersson, L. Folkersen, Linda Fogelstrand, Ulrika Islander, Z. Q. Yan, G. K. Hansson
Arteriosclerosis Thrombosis and Vascular Biology - 2014 -
The role of total and cartilage-specific estrogen receptor alpha expression for the ameliorating effect of estrogen treatment on
arthritis.
Cecilia Engdahl, Anna E Börjesson, Huamei Forsman, Annica Andersson, Alexandra Stubelius, Andree Krust, Pierre Chambon, Ulrika Islander, Claes Ohlsson, Hans Carlsten, Marie K Lagerquist
Arthritis research & therapy - 2014 -
Probiotics protect mice from ovariectomy-induced cortical bone
loss.
Claes Ohlsson, Cecilia Engdahl, Frida Fåk, Annica Andersson, Sara H Windahl, Helen H. Farman, Sofia Movérare-Skrtic, Ulrika Islander, Klara Sjögren
PloS one - 2014 -
Immunomodulation by the estrogen metabolite
2-methoxyestradiol
Alexandra Stubelius, Malin Erlandsson, Ulrika Islander, Hans Carlsten
Clinical Immunology - 2014 -
The role of activation functions 1 and 2 of estrogen receptor-alpha for the effects of estradiol and selective estrogen receptor modulators in male
mice
Anna E Börjesson, Helen H. Farman, Cecilia Engdahl, A. Koskela, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Hans Carlsten, M. C. Antal, A. Krust, P. Chambon, J. Tuukkanen, Marie K Lagerquist, Sara H Windahl, Claes Ohlsson
Journal of Bone and Mineral Research - 2013 -
Sexual dimorphisms in the immune system of catechol-O-methyltransferase knockout
mice
Alexandra Stubelius, Anna S K Wilhelmson, J. A. Gogos, Åsa Tivesten, Ulrika Islander, Hans Carlsten
Immunobiology - 2012 -
Role of 2-methoxyestradiol as inhibitor of arthritis and osteoporosis in a model of postmenopausal rheumatoid
arthritis
Alexandra Stubelius, Emil Andréasson, Anna Karlsson, Claes Ohlsson, Åsa Tivesten, Ulrika Islander, Hans Carlsten
Clinical Immunology - 2011 -
Response to Letter by X. Li, Q. Y. Zhou, F. L. Yuan. Galectin-3 as a novel therapeutic target in rheumatoid arthritis: comment on the article by Forsman et
al
Huamei Forsman, Ulrika Islander, Anna Karlsson
Arthritis and Rheumatism - 2011 -
Effects of oestradiol and raloxifene on the induction and effector phases of experimental postmenopausal arthritis and secondary
osteoporosis
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Claes Ohlsson, Kutty Selva Nandakumar, Rikard Holmdahl, Hans Carlsten
Clinical and Experimental Immunology - 2011 -
Roles of transactivating functions 1 and 2 of estrogen receptor-alpha in
bone.
Anna E Börjesson, Sara H Windahl, Marie Lagerquist, Cecilia Engdahl, B Frenkel, Sofia Movérare-Skrtic, Klara Sjögren, Jenny Kindblom, Alexandra Stubelius, Ulrika Islander, Mc Antal, A Krust, P Chambon, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 2011 -
Estrogens in rheumatoid arthritis; the immune system and
bone
Ulrika Islander, Caroline Jochems, Marie Lagerquist, Helena Forsblad d'Elia, Hans Carlsten
Molecular and Cellular Endocrinology - 2011 -
Combined treatment with Dexamethasone and Raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal
arthritis
Ulrika Islander, Caroline Jochems, Alexandra Stubelius, Annica Andersson, Marie Lagerquist, Claes Ohlsson, Hans Carlsten
Arthritis Research and Therapy - 2011 -
Galectin-3 aggravates joint inflammation and destruction in antigen-induced
arthritis.
Huamei Forsman, Ulrika Islander, Emil Andréasson, Annica Andersson, Karin Önnheim, Alexandra Karlström, Karin Sävman, Mattias Magnusson, Kelly Brown, Anna Karlsson
Arthritis and rheumatism - 2011 -
Role of endogenous and exogenous female sex hormones in arthritis and osteoporosis development in B10.Q-ncf1*/* mice with collagen-induced chronic
arthritis.
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Cecilia Engdahl, Marie Lagerquist, Inger Gjertsson, Claes Ohlsson, Rikard Holmdahl, Hans Carlsten
BMC musculoskeletal disorders - 2010 -
Superantigenic Staphylococcus aureus stimulate production of IL-17 from memory but not naive T
cells.
Ulrika Islander, Annica Andersson, Erika Lindberg, Ingegerd Adlerberth, Agnes E Wold, Anna Rudin
Infection and immunity - 2010 -
17Beta-estradiol expands IgA-producing B cells in mice deficient for the mu
chain.
Marie Lagerquist, Malin Erlandsson, L Svensson, Ulrika Islander, R Holmdahl, Hans Carlsten
Scandinavian journal of immunology - 2008 -
Ethanol prevents development of destructive
arthritis
Ing-Marie Jonsson, Margareta Verdrengh, Mikael Brisslert, Sofia Silfverswärd Lindblad, Maria Bokarewa, Ulrika Islander, Hans Carlsten, Claes Ohlsson, K. S. Nandakumar, R. Holmdahl, Andrej Tarkowski
Proc Natl Acad Sci U S A - 2007 -
Role of raloxifene as a potent inhibitor of experimental postmenopausal polyarthritis and
osteoporosis
Caroline Jochems, Ulrika Islander, Anna Kallkopf, Marie Lagerquist, Claes Ohlsson, Hans Carlsten
Arthritis Rheum - 2007 -
Immunomodulation by estrogen and
estren
Ulrika Islander
2007 -
Estren promotes androgen phenotypes in primary lymphoid organs and submandibular
glands
Ulrika Islander, Bengt Hasséus, Malin Erlandsson, Caroline Jochems, Sofia Movérare-Skrtic, Marie Lindberg, J. A. Gustafsson, Claes Ohlsson, Hans Carlsten
BMC Immunology - 2005 -
Estren-mediated inhibition of T lymphopoiesis is estrogen receptor-independent whereas its suppression of T cell-mediated inflammation is estrogen
receptor-dependent
Ulrika Islander, Malin Erlandsson, Tina Chavoshi, Caroline Jochems, Sofia Movérare-Skrtic, S. Nilsson, Claes Ohlsson, J. A. Gustafsson, Hans Carlsten
Clin Exp Immunol - 2005 -
Osteoporosis in experimental postmenopausal polyarthritis: the relative contributions of estrogen deficiency and
inflammation
Caroline Jochems, Ulrika Islander, Malin Erlandsson, Margareta Verdrengh, Claes Ohlsson, Hans Carlsten
Arthritis Res Ther - 2005 -
Investigation of central versus peripheral effects of estradiol in ovariectomized
mice
Niklas Andersson, Ulrika Islander, Emil Egecioglu, Elin Löf, Charlotte Swanson, Sofia Movérare-Skrtic, Klara Sjögren, Marie Lindberg, Hans Carlsten, Claes Ohlsson
J Endocrinol - 2005 -
Estrogenic agonism and antagonism of the soy isoflavone genistein in uterus, bone and lymphopoiesis in
mice
-
Estren is a selective estrogen receptor modulator with transcriptional
activity.
Sofia Movérare, Johanna Dahllund, Niklas Andersson, Ulrika Islander, Hans Carlsten, Jan-Ake Gustafsson, Stefan Nilsson, Claes Ohlsson
Molecular pharmacology - 2003 -
Influence of oestrogen receptor alpha and beta on the immune system in aged female
mice.
Ulrika Islander, M C Erlandsson, Bengt Hasséus, C A Jonsson, Claes Ohlsson, J-A Gustafsson, Ulf Dahlgren, Hans Carlsten
Immunology - 2003 -
Oestrogen receptor specificity in oestradiol-mediated effects on B lymphopoiesis and immunoglobulin production in male
mice.
M C Erlandsson, C A Jonsson, Ulrika Islander, Claes Ohlsson, Hans Carlsten
Immunology - 2003