- Hem
- Om universitetet
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- Marcus Henricsson
Marcus Henricsson
Forskningsingenjör 1.e
Avd för molekylär och klinisk medicin-
Aging AdipoR2-deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty
acids
Mario Ruiz, Ranjan Devkota, Per-Olof Bergh, Ali Moussavi Nik, Sebastian Sköldheden, Jorge Mondejar-Duran, Maximilian Tufvesson-Alm, Mohammad Bohlooly-Y, Diego Sanchez, Peter Carlsson, Marcus Henricsson, Elisabeth Jerlhag, Jan Borén, Marc Pilon
The FASEB Journal - 2024 -
Production of deoxycholic acid by low-abundant microbial species is associated with impaired glucose
metabolism
Annika Wahlström, Ariel Brumbaugh, Wilhelm Sjöland, Lisa M. Olsson, Hao Wu, Marcus Henricsson, Annika Lundqvist, Kassem Makki, Stanley L. Hazen, Göran Bergström, Hanns-Ulrich Marschall, Michael A. Fischbach, Fredrik Bäckhed
NATURE COMMUNICATIONS - 2024 -
Adipocyte PI3K links adipostasis with baseline insulin secretion at fasting through an adipoincretin
effect.
Barbara Becattini, Angela Molinaro, Marcus Henricsson, Jan Borén, Giovanni Solinas
Cell reports - 2024 -
Regulation of meiotic telomere dynamics through membrane fluidity promoted by
AdipoR2-ELOVL2
Jingjing Zhang, Mario Ruiz, Per-Olof Bergh, Marcus Henricsson, Nena Stojanovic, Ranjan Devkota, Marius Henn, Mohammad Bohlooly-Y, Abrahan Hernandez-Hernandez, Manfred Alsheimer, Jan Borén, Marc Pilon, Hiroki Shibuya
NATURE COMMUNICATIONS - 2024 -
Alterations in bile acid kinetics after bariatric surgery in patients with obesity with or without type 2
diabetes
Annika Wahlström, Omrum Aydin, Lisa M. Olsson, Wilhelm Sjoland, Marcus Henricsson, Annika Lundqvist, Hanns-Ulrich Marschall, Rutger Franken, Arnold van de Laar, Victor Gerdes, Abraham S. Meijnikman, Dag Hofso, Albert K. Groen, Joran Hjelmesaeth, Max Nieuwdorp, Fredrik Bäckhed
EBIOMEDICINE - 2024 -
AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane
fluidity
Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uros Radovic, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon
Journal of Biological Chemistry - 2023 -
6 alpha-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon dietary fiber supplementation in
mice
Kassem Makki, Harald Brolin, N. Petersen, Marcus Henricsson, D. P. Christensen, Muhammad Tanweer Khan, Annika Wahlström, Per-Olof Bergh, Valentina Tremaroli, K. Schoonjans, Hanns-Ulrich Marschall, Fredrik Bäckhed
Gut - 2023 -
Cerebrospinal fluid sulfatide isoforms lack diagnostic utility in separating progressive from relapsing-remitting multiple
sclerosis.
Lenka Novakova, Marcus Henricsson, Elias Björnson, Markus Axelsson, Jan Borén, Igal Rosenstein, Jan Lycke, Susanna Cardell, Maria K. Blomqvist
Multiple sclerosis and related disorders - 2023 -
Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart
function.
Marion Laudette, Malin Lindbom, Muhammad Arif, Mathieu Cinato, Mario Ruiz, Stephen Doran, Azra Miljanovic, Mikael Rutberg, Linda Andersson, Martina Klevstig, Marcus Henricsson, Per-Olof Bergh, Entela Bollano, Nay Aung, J. Gustav Smith, Marc Pilon, Tuulia Hyötyläinen, Matej Orešič, Rosie Perkins, Adil Mardinoglu, Malin Levin, Jan Borén
Cardiovascular research - 2023 -
Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte
contractility
Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Christina Drevinge, Marion Laudette, Entela Bollano, Marcus Henricsson, Johan Tolö, Marco Bauzá-Thorbrügge, Max Levin, Malin Lindbom, M. Arif, P. Pacher, Linda Andersson, Charlotta S Olofsson, Jan Borén, Malin Levin
Life Science Alliance - 2023 -
The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and
dyslipidemia
A. Mahdi, T. Wodaje, O. Kovamees, J. Tengbom, A. Zhao, T. Jiao, Marcus Henricsson, J. N. Yang, Z. C. Zhou, A. I. Nieminen, Malin Levin, A. Collado, J. Brinck, J. Pernow
Journal of Internal Medicine - 2023 -
Postprandial metabolism of apolipoproteins B48, B100, C-III, and E in humans with APOC3 loss-of-function
mutations
M. R. Taskinen, Elias Björnson, N. Matikainen, S. Soderlund, J. Ramo, M. M. Ainola, A. Hakkarainen, C. Sihlbom, A. Thorsell, Linda Andersson, Per-Olof Bergh, Marcus Henricsson, Stefano Romeo, Martin Adiels, S. Ripatti, M. Laakso, C. J. Packard, Jan Borén
Jci Insight - 2022 -
Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and
embryogenesis.
Mario Ruiz, Ranjan Devkota, Dimitra Panagaki, Per-Olof Bergh, Delaney Kaper, Marcus Henricsson, Ali Nik, Kasparas Petkevicius, Johanna L Höög, Mohammad Bohlooly-Y, Peter Carlsson, Jan Borén, Marc Pilon
Nature communications - 2022 -
Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing
cholangitis
P. R. Braadland, K. M. Schneider, A. Bergquist, Antonio Molinaro, A. Lovgren-Sandblom, Marcus Henricsson, T. H. Karlsen, M. Vesterhus, C. Trautwein, J. R. Hov, Hanns-Ulrich Marschall
Jhep Reports - 2022 -
Inhibition of MAP4K4 signaling initiates metabolic reprogramming to protect hepatocytes from lipotoxic
damage
Sumit Kumar Anand, Mara Caputo, Ying Xia, Emma Andersson, Emmelie Cansby, Sima Kumari, Marcus Henricsson, R. Porosk, Katharina Keuenhof, Johanna L Höög, Syam Nair, Hanns-Ulrich Marschall, M. Bluher, Margit Mahlapuu
Journal of Lipid Research - 2022 -
Tetrahydroxylated bile acids improve cholestatic liver and bile duct injury in the Mdr2(-/-) mouse model of sclerosing cholangitis via immunomodulatory
effects
C. D. Fuchs, E. D. Dixon, T. Hendrikx, V. Mlitz, Annika Wahlström, Marcus Ståhlman, H. Scharnagl, T. Stojakovic, C. J. Binder, Hanns-Ulrich Marschall, M. Trauner
Hepatology communications. - 2022 -
Effects of pnpla3 i148m on hepatic lipid and very low-density lipoprotein metabolism in
humans.
Jan Borén, Martin Adiels, Elias Björnson, Niina Matikainen, Sanni Söderlund, Joel Rämö, Marcus Ståhlman, Pietari Ripatti, Samuli Ripatti, Aarno Palotie, Rosellina Margherita Mancina, Mari Ainola, Antti Hakkarainen, Stefano Romeo, Chris J Packard, Marja-Riitta Taskinen
Journal of internal medicine - 2022 -
Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over
study
A. Koopen, J. Witjes, K. Wortelboer, S. Majait, A. Prodan, E. Levin, H. Herrema, M. Winkelmeijer, S. Aalvink, Jjghm Bergman, S. Havik, B. Hartmann, H. Levels, Per-Olof Bergh, J. van Son, M. Balvers, D. M. Bastos, E. Stroes, A. K. Groen, Marcus Henricsson, E. M. Kemper, J. Holst, C. M. Strauch, S. L. Hazen, Fredrik Bäckhed, W. M. De Vos, M. Nieuwdorp, E. Rampanelli
Gut - 2022 -
Modified lipid metabolism and cytosolic phospholipase A2 activation in mesangial cells under pro-inflammatory
conditions
Roberto Boi, Kerstin Ebefors, Marcus Henricsson, Jan Borén, Jenny Nyström
Scientific Reports - 2022 -
Challenging the Hypothesis of de novo Biosynthesis of Bile Acids by Marine
Bacteria
F. G. Tueros, M. M. Hashim Ellabaan, Marcus Henricsson, R. Vazquez-Uribe, Fredrik Bäckhed, M. O. A. Sommer
Microbiology and Biotechnology Letters - 2022 -
Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor
trafficking.
Linda Andersson, Mathieu Cinato, Ismena Mardani, Azra Miljanovic, Arif Mohammed, Ara Koh, Malin Lindbom, Marion Laudette, Entela Bollano, Elmir Omerovic, Martina Klevstig, Marcus Henricsson, Per Fogelstrand, Karl Swärd, Matias Ekstrand, Max Levin, Johannes Wikström, Stephen Doran, Tuulia Hyötyläinen, Lisanna Sinisalu, Matej Oresic, Åsa Tivesten, Martin Adiels, Martin O Bergo, Richard Proia, Adil Mardinoglu, Anders Jeppsson, Jan Borén, Malin Levin
European heart journal - 2021 -
(CO2)n+, (H2O)n+, and (H2O)n+ (CO2) gas cluster ion beam secondary ion mass spectrometry: analysis of lipid extracts, cells, and Alzheimer’s model mouse brain
tissue
Kelly Dimovska Nilsson, Anthi Karagianni, Ibrahim Kaya, Marcus Henricsson, John S. Fletcher
Analytical and Bioanalytical Chemistry - 2021 -
Plasma Imidazole Propionate Is Positively Correlated with Blood Pressure in Overweight and Obese
Humans
J. van Son, M. J. Serlie, Marcus Ståhlman, Fredrik Bäckhed, M. Nieuwdorp, J. Aron-Wisnewsky
Nutrients - 2021 -
Testosterone reduces metabolic brown fat activity in male
mice
Marta Lantero Rodriguez, M. Schilperoort, Inger Johansson, Elin Svedlund Eriksson, Vilborg Palsdottir, J. Kroon, Marcus Henricsson, S. Kooijman, Mia Ericson, Jan Borén, Claes Ohlsson, John-Olov Jansson, Malin Levin, P. C. N. Rensen, Åsa Tivesten
Journal of Endocrinology - 2021 -
Silencing of STE20-type kinase MST3 in mice with antisense oligonucleotide treatment ameliorates diet-induced nonalcoholic fatty liver
disease
Mara Caputo, Yeshwant Kurhe, Sima Kumari, Emmelie Cansby, M. Amrutkar, E. Scandalis, S. L. Booten, Marcus Ståhlman, Jan Borén, Hanns-Ulrich Marschall, M. Aghajan, Margit Mahlapuu
FASEB Journal - 2021 -
STE20-type kinase TAOK3 regulates hepatic lipid
partitioning
Ying Xia, Mara Caputo, Emmelie Cansby, Sumit Kumar Anand, Silva Sütt, Marcus Henricsson, R. Porosk, H. U. Marschall, M. Bluher, Margit Mahlapuu
Molecular Metabolism - 2021 -
A genetic titration of membrane composition in Caenorhabditis elegans reveals its importance for multiple cellular and physiological
traits
Ranjan Devkota, Delaney Kaper, Rakesh Bodhicharla, Marcus Henricsson, Jan Borén, Marc Pilon
Genetics - 2021 -
Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple
myeloma
Lenka Besse, Andrej Besse, Sara C. Stolze, Amin Sobh, Esther A. Zaal, Alwin J.Van Der Ham, Mario Ruiz, Santosh Phuyal, Lorina Buchler, Marc Sathianathan, Bogdan I. Florea, Jan Borén, Marcus Ståhlman, Julia Huber, Arnold Bolomsky, Heinz Ludwig, J. Thomas Hannich, Alex Loguinov, Bart Everts, Celia R. Berkers, Marc Pilon, Hesso Farhan, Christopher D. Vulpe, Herman S. Overkleeft, Christoph Driessen
Cancer Research - 2021 -
Cerebrospinal Fluid Sulfatide Levels Lack Diagnostic Utility in the Subcortical Small Vessel Type of
Dementia.
Johan Svensson, Maria K. Blomqvist, Petronella Kettunen, Carl Eckerström, Marcus Henricsson, Michael Jonsson, Maria Bjerke, Jan-Eric Månsson, Anders Wallin
Journal of Alzheimer's disease : JAD - 2021 -
Palmitic acid causes increased dihydroceramide levels when desaturase expression is directly silenced or indirectly lowered by silencing
AdipoR2
Mario Ruiz, Marcus Henricsson, Jan Borén, Marc Pilon
Lipids in Health and Disease - 2021 -
Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR
signalling
K. M. Schneider, L. S. Candels, J. R. Hov, M. Myllys, R. Hassan, C. V. Schneider, Annika Wahlström, A. Mohs, S. Zuhlke, L. J. Liao, C. Elfers, K. Kilic, Marcus Henricsson, Antonio Molinaro, M. Hatting, A. Zaza, D. Drasdo, M. Frissen, A. S. Devlin, E. J. C. Galvez, T. Strowig, T. H. Karlsen, J. G. Hengstler, Hanns-Ulrich Marschall, A. Ghallab, C. Trautwein
Nature Metabolism - 2021 -
Sacubitril/valsartan decreases mortality in the rat model of the isoprenaline-induced takotsubo-like
syndrome
Anwar Ali Gasim Elsied, Björn Redfors, Jessica Alkhoury, Jonatan Oras, Marcus Henricsson, Jan Borén, Elias Björnson, Aaron Shekka Espinosa, Malin Levin, Li-Ming Gan, Elmir Omerovic
ESC Heart Failure - 2021 -
STE20-Type Protein Kinase MST4 Controls NAFLD Progression by Regulating Lipid Droplet Dynamics and Metabolic Stress in
Hepatocytes
Mara Caputo, Emmelie Cansby, Sima Kumari, Yeshwant Kurhe, Syam Nair, Marcus Ståhlman, Nagaraj M. Kulkarni, Jan Borén, Hanns-Ulrich Marschall, M. Bluher, Margit Mahlapuu
Hepatology Communications - 2021 -
Short Article Hypothalamic bile acid-TGR5 signaling protects from
obesity
A. Castellanos-Jankiewicz, O. Guzman-Quevedo, V. S. Fenelon, P. Zizzari, C. Quarta, L. Bellocchio, A. Tailleux, J. Charton, D. Fernandois, Marcus Henricsson, C. Piveteau, V. Simon, C. Allard, S. Quemener, V. Guinot, N. Hennuyer, A. Perino, A. Duveau, M. Maitre, T. Leste-Lasserre, S. Clark, N. Dupuy, A. Cannich, D. Gonzales, B. Deprez, G. Mithieux, D. Dombrowicz, Fredrik Bäckhed, V. Prevot, G. Marsicano, B. Staels, K. Schoonjans, D. Cota
Cell Metabolism - 2021 -
The C. elegans PAQR-2 and IGLR-2 membrane homeostasis proteins are uniquely essential for tolerating dietary saturated
fats
Ranjan Devkota, Marcus Henricsson, Jan Borén, Marc Pilon
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids - 2021 -
Extensive transcription mis-regulation and membrane defects in AdipoR2-deficient cells challenged with saturated fatty
acids
Mario Ruiz, H. Palmgren, Marcus Henricsson, Ranjan Devkota, H. Jaiswal, M. Maresca, M. Bohlooly-Y, X. R. Peng, Jan Borén, Marc Pilon
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids - 2021 -
Association of dietary and gut microbiota-related metabolites with calcific aortic
stenosis
K. Duygu, L. Tokgozoglu, K. M. Gurses, Marcus Ståhlman, Jan Borén, M. F. T. Soyal, H. Canpinar, D. Guc, A. S. Ayhan, T. Hazirolan, N. Ozer
Acta Cardiologica - 2021 -
The Food Contaminants Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis Structure-Dependently in the Human Hepatoma Cell Line
HepaRG
J. Gluck, Marcus Henricsson, A. Braeuning, S. Hessel-Pras
Foods - 2021 -
Pyrrolizidine Alkaloids Disturb Bile Acid Homeostasis in the Human Hepatoma Cell Line
HepaRG
J. Waizenegger, J. Gluck, Marcus Henricsson, C. Luckert, A. Braeuning, S. Hessel-Pras
Foods - 2021 -
Antioxidants promote intestinal tumor progression in
mice.
Zhiyuan V. Zou, Kristell Le Gal, Ahmed E El Zowalaty, Lara Pehlivanoglu, Viktor Garellick, Nadia Gul, Mohamed X Ibrahim, Per-Olof Bergh, Marcus Henricsson, Clotilde Wiel, Levent Akyürek, Martin Bergö, Volkan I. Sayin, Per Lindahl
Antioxidants - 2021 -
Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in
Mice
Kristell Le Gal, Clotilde Wiel, M. X. Ibrahim, Marcus Henricsson, Volkan I. Sayin, M. O. Bergo
Antioxidants - 2021 -
Feeding diversified protein sources exacerbates hepatic insulin resistance via increased gut microbial branched-chain fatty acids and mTORC1 signaling in obese
mice
B. S. Y. Choi, N. Daniel, V. P. Houde, A. Ouellette, B. Marcotte, T. V. Varin, C. Vors, P. Feutry, O. Ilkayeva, Marcus Ståhlman, P. St-Pierre, Fredrik Bäckhed, A. Tremblay, P. J. White, A. Marette
Nature Communications - 2021 -
Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR
proteins
Kiran Busayavalasa, Mario Ruiz, Ranjan Devkota, Marcus Ståhlman, Rakesh Bodhicharla, Emma Svensk, N. O. Hermansson, Jan Borén, Marc Pilon
Plos Genetics - 2020 -
Absence of Bsep/Abcb11 attenuates MCD diet-induced hepatic steatosis but aggravates inflammation in
mice
C. D. Fuchs, S. Krivanec, D. Steinacher, V. Mlitz, Annika Wahlström, Marcus Ståhlman, T. Claudel, H. Scharnagl, T. Stojakovic, Hanns-Ulrich Marschall, M. Trauner
Liver International - 2020 -
A 7-day high-fat, high-calorie diet induces fibre-specific increases in intramuscular triglyceride and perilipin protein expression in human skeletal
muscle
K. L. Whytock, S. A. Parry, M. C. Turner, R. M. Woods, L. J. James, R. A. Ferguson, Marcus Ståhlman, Jan Borén, J. A. Strauss, M. Cocks, A. J. M. Wagenmakers, C. J. Hulston, S. O. Shepherd
Journal of Physiology-London - 2020 -
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver
disease.
Cheng Zhang, Elias Björnson, Muhammad Arif, Abdellah Tebani, Alen Lovric, Rui Benfeitas, Mehmet Ozcan, Kajetan Juszczak, Woonghee Kim, Jung Tae Kim, Gholamreza Bidkhori, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, Hasan Turkez, Marja-Riitta Taskinen, Jim Bosley, Hanns-Ulrich Marschall, Jens Nielsen, Mathias Uhlén, Jan Borén, Adil Mardinoglu
Molecular systems biology - 2020 -
Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic
subjects
M. R. Taskinen, Elias Björnson, Linda Andersson, J. Kahri, K. Porthan, N. Matikainen, S. Soderlund, K. Pietilainen, A. Hakkarainen, N. Lundbom, R. Nilsson, Marcus Ståhlman, Martin Adiels, P. Parini, C. Packard, Jan Borén
Journal of Clinical Lipidology - 2020 -
Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in
humans.
Jan Borén, Martin Adiels, Elias Björnson, Nina Matikainen, Sanni Söderlund, Joel T Rämo, Marcus Ståhlman, Puetaru Ripatti, Samuli Ripatti, Aarno Palotie, Rosellina Margherita Mancina, Antti Hakkarainen, Stefano Romeo, Chris j Packard, Marja-Riitta Taskinen
JCI insight - 2020 -
Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney
disease.
Emmelie Cansby, Mara Caputo, Lei Gao, Nagaraj M. Kulkarni, Annika Nerstedt, Marcus Ståhlman, Jan Borén, Rando Porosk, Ursel Soomets, Matteo Pedrelli, Paolo Parini, Hanns-Ulrich Marschall, Jenny Nyström, Brian W Howell, Margit Mahlapuu
JCI insight - 2020 -
Lipid profiling of human diabetic myocardium reveals differences in triglyceride fatty acyl chain length and degree of
saturation.
Elias Björnson, Ylva Östlund, Marcus Ståhlman, Martin Adiels, Elmir Omerovic, Anders Jeppsson, Jan Borén, Malin Levin
International journal of cardiology - 2020 -
Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic
pregnancy
C. Ovadia, A. Perdones-Montero, H. M. Fan, B. H. Mullish, J. A. K. McDonald, G. Papacleovoulou, Annika Wahlström, Marcus Ståhlman, A. Tsakmaki, L. C. D. Clarke, A. Sklavounos, P. H. Dixon, G. A. Bewick, J. R. F. Walters, Hanns-Ulrich Marschall, J. R. Marchesi, C. Williamson
Scientific Reports - 2020 -
Histo-blood group antigens of glycosphingolipids predict susceptibility of human intestinal enteroids to norovirus
infection
Inga Rimkute, K. Thorsteinsson, Marcus Henricsson, V. R. Tenge, X. M. Yu, S. C. Lin, K. Haga, R. L. Atmar, Nils Y Lycke, Jonas Nilsson, M. K. Estes, M. Bally, Göran Larson
Journal of Biological Chemistry - 2020 -
Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial
ecology
Antonio Molinaro, Py Bel Lassen, Marcus Henricsson, Hao Wu, S. Adriouch, E. Belda, R. Chakaroun, T. Nielsen, Per-Olof Bergh, C. Rouault, S. Andre, F. Marquet, F. Andreelli, J. E. Salem, K. Assmann, J. P. Bastard, S. Forslund, E. Le Chatelier, G. Falony, N. Pons, E. Prifti, B. Quinquis, H. Roume, S. Vieira-Silva, T. H. Hansen, H. K. Pedersen, C. Lewinter, N. B. Sonderskov, L. Kober, H. Vestergaard, T. Hansen, J. D. Zucker, P. Galan, M. E. Dumas, J. Raes, J. M. Oppert, I. Letunic, J. Nielsen, P. Bork, S. D. Ehrlich, M. Stumvoll, O. Pedersen, J. Aron-Wisneswky, K. Clement, Fredrik Bäckhed
Nature Communications - 2020 -
A Short-Term Western Diet Impairs Cholesterol Homeostasis and Key Players of Beta Amyloid Metabolism in Brain of Middle Aged
Rats
M. S. Spagnuolo, V. Pallottini, A. Mazzoli, L. Iannotta, C. Tonini, B. Morone, Marcus Ståhlman, R. Crescenzo, M. Strazzullo, S. Iossa, L. Cigliano
Molecular Nutrition & Food Research - 2020 -
Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin
resistance
K. H. M. Roumans, L. Lindeboom, P. Veeraiah, C. M. E. Remie, E. Phielix, B. Havekes, Y. M. H. Bruls, Mcgj Brouwers, Marcus Ståhlman, M. Alssema, H. P. F. Peters, R. de Mutsert, B. Staels, M. R. Taskinen, Jan Borén, P. Schrauwen, V. B. Schrauwen-Hinderling
Nature Communications - 2020 -
Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic
liver
Annika Nerstedt, Yeshwant Kurhe, Emmelie Cansby, Mara Caputo, Lei Gao, Egor Vorontsov, Marcus Ståhlman, Esther Nuñez Durán, Jan Borén, Hanns-Ulrich Marschall, Douglas G. Mashek, D. N. Saunders, Carina Sihlbom, A. J. Hoy, Margit Mahlapuu
Journal of Lipid Research - 2020 -
Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit
time
P. De Groot, T. Scheithauer, G. J. Bakker, A. Prodan, E. Levin, Muhammad Tanweer Khan, H. Herrema, M. Ackermans, M. J. M. Serlie, M. De Brauw, J. H. M. Levels, A. Sales, Marcus Ståhlman, A. W. M. Schimmel, G. Dallinga-Thie, J. J. Bergman, F. Holleman, J. B. L. Hoekstra, A. Groen, Fredrik Bäckhed, M. Nieuwdorp
Gut - 2020 -
Associations between Dietary Patterns and Bile Acids-Results from a Cross-Sectional Study in Vegans and
Omnivores
I. Trefflich, Hanns-Ulrich Marschall, R. di Giuseppe, Marcus Ståhlman, A. Michalsen, A. Lampen, K. Abraham, C. Weikert
Nutrients - 2020 -
Obesity-associated microbiota contributes to mucus layer defects in genetically obese
mice
Björn O. Schröder, George M. H. Birchenough, Meenakshi Pradhan, Elisabeth E. L. Nyström, Marcus Henricsson, Gunnar C. Hansson, Fredrik Bäckhed
Journal of Biological Chemistry - 2020 -
Impairment of bile acid metabolism by perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in human HepaRG hepatoma
cells
A. C. Behr, A. Kwiatkowski, Marcus Ståhlman, F. F. Schmidt, C. Luckert, A. Braeuning, T. Buhrke
Archives of Toxicology - 2020 -
Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient
mice
S. Keipert, D. Lutter, Björn O. Schröder, D. Brandt, Marcus Ståhlman, T. Schwarzmayr, E. Graf, H. Fuchs, M. H. de Angelis, M. H. Tschop, J. Rozman, M. Jastroch
Nature Communications - 2020 -
Obeticholic acid may increase the risk of gallstone formation in susceptible
patients.
Samer Al-Dury, Annika Wahlström, Katrin Panzitt, Anders Thorell, Marcus Ståhlman, Michael Trauner, Peter Fickert, Fredrik Bäckhed, Lars Fändriks, Martin Wagner, Hanns-Ulrich Marschall
Journal of hepatology - 2019 -
Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in
humans.
Emmelie Cansby, Nagaraj M. Kulkarni, Elin Magnusson, Yeshwant Kurhe, Manoj Amrutkar, Annika Nerstedt, Marcus Ståhlman, Carina Sihlbom, Hanns-Ulrich Marschall, Jan Borén, Matthias Blüher, Margit Mahlapuu
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019 -
Liver-specific RORα deletion does not affect the metabolic susceptibility to western style diet
feeding.
Antonio Molinaro, Robert Caesar, Laurent L'homme, Ara Koh, Marcus Ståhlman, Bart Staels, Fredrik Bäckhed
Molecular metabolism - 2019 -
Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in
mice.
Daniel Lindén, Andrea Ahnmark, Piero Pingitore, Ester Ciociola, Ingela Ahlstedt, Anne-Christine Andréasson, Kavitha Sasidharan, Katja Madeyski-Bengtson, Magdalena Zurek, Rosellina Margherita Mancina, Anna Lindblom, Mikael Bjursell, Gerhard Böttcher, Marcus Ståhlman, Mohammad Bohlooly-Yeganeh, William G Haynes, Björn Carlsson, Mark Graham, Richard Lee, Sue Murray, Luca Valenti, Sanjay Bhanot, Peter Åkerblad, Stefano Romeo
Molecular metabolism - 2019 -
Evolutionarily conserved long-chain Acyl-CoA synthetases regulate membrane composition and
fluidity
Mario Ruiz, Rakesh Bodhicharla, Marcus Ståhlman, Emma Svensk, Kiran Busayavalasa, H. Palmgren, H. Ruhanen, Jan Borén, Marc Pilon
Elife - 2019 -
Cardiac expression of the microsomal triglyceride transport protein protects the heart function during
ischemia
Martina Klevstig, M. Arif, M. Mannila, S. Svedlund, Ismena Mardani, Marcus Ståhlman, Linda Andersson, Malin Lindbom, Azra Miljanovic, A. Franco-Cereceda, P. Eriksson, Anders Jeppsson, Li-Ming Gan, Malin Levin, A. Mardinoglu, E. Ehrenborg, Jan Borén
Journal of Molecular and Cellular Cardiology - 2019 -
AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of
adiponectin
Mario Ruiz, Marcus Ståhlman, Jan Borén, Marc Pilon
Journal of Lipid Research - 2019 -
Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the
heart.
Ismena Mardani, Dalen Knut Tomas, Christina Drevinge, Azra Miljanovic, Marcus Ståhlman, Martina Klevstig, Margareta Scharin Täng, Per Fogelstrand, Max Levin, Matias Ekstrand, Syam Nair, Björn Redfors, Elmir Omerovic, Linda Andersson, Kimmel Alan R, Jan Borén, Malin Levin
Scientific reports - 2019 -
Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial
function
Z. T. Liu, C. Zhang, S. Lee, W. Kim, Martina Klevstig, A. M. Harzandi, N. Sikanic, M. Arif, Marcus Ståhlman, J. Nielsen, M. Uhlen, Jan Borén, A. Mardinoglu
Metabolic Engineering - 2019 -
Localised lipid accumulation detected in infarcted mouse heart tissue using
ToF-SIMS
S. Samfors, Marcus Ståhlman, Martina Klevstig, Jan Borén, John S. Fletcher
International Journal of Mass Spectrometry - 2019 -
Overeating Saturated Fat Promotes Fatty Liver and Ceramides Compared With Polyunsaturated Fat: A Randomized
Trial
F. Rosqvist, J. Kullberg, Marcus Ståhlman, J. Cedernaes, Kerstin Heurling, H. E. Johansson, D. Iggman, H. Wilking, A. Larsson, O. Eriksson, L. Johansson, S. Straniero, M. Rudling, G. Antoni, M. Lubberink, M. Orho-Melander, Jan Borén, H. Ahlström, U. Risérus
The Journal of clinical endocrinology and metabolism - 2019 -
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through
mTORC1
Ara Koh, Antonio Molinaro, Marcus Ståhlman, Muhammad Tanweer Khan, Caroline Schmidt, Louise Mannerås Holm, Hao Wu, Alba Carreras, Louise Olofsson, Per-Olof Bergh, V. Gerdes, A. Hartstra, M. de Brauw, Rosie Perkins, Max Nieuwdorp, Göran Bergström, Fredrik Bäckhed
Cell - 2018 -
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic
leukodystrophy
G. Frati, M. Luciani, V. Meneghini, S. De Cicco, Marcus Ståhlman, Maria K. Blomqvist, S. Grossi, M. Filocamo, F. Morena, A. Menegon, S. Martino, A. Gritti
Cell Death & Disease - 2018 -
STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of
Hypercholesterolemia
Emmelie Cansby, Elin Magnusson, Esther Nuñez Durán, M. Amrutkar, M. Pedrelli, P. Parini, Jenny M Hoffmann, Marcus Ståhlman, B. W. Howell, Hanns-Ulrich Marschall, Jan Borén, Margit Mahlapuu
Arteriosclerosis Thrombosis and Vascular Biology - 2018 -
Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial
Cells
Cristopher McCrae, A. Dzgoev, Marcus Ståhlman, J. Horndahl, R. Svard, A. Grosse, T. Grosskopf, M. A. Skujat, N. Williams, S. Schubert, C. Echeverri, C. Jackson, A. Guedan, R. Solari, O. Vaarala, M. Kraan, Madeleine Rådinger
American Journal of Respiratory Cell and Molecular Biology - 2018 -
Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in
mice
Liliana Håversen, J. P. Sundelin, A. Mardinoglu, Mikael Rutberg, Marcus Ståhlman, Ulrika Wilhelmsson, Lillemor Mattsson Hultén, Milos Pekny, Per Fogelstrand, J. F. Bentzon, Malin Levin, Jan Borén
Scientific Reports - 2018 -
Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and
metabolome
A. Lovric, M. Graner, E. Bjornson, M. Arif, R. Benfeitas, K. Nyman, Marcus Ståhlman, M. O. Pentikainen, J. Lundborn, A. Hakkarainen, R. Siren, M. S. Nieminen, N. Lundborns, K. Lauermas, M. R. Taskinen, A. Mardinoglu, Jan Borén
Scientific Reports - 2018 -
Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile
acids.
Claudia Daniela Fuchs, Gustav Paumgartner, Veronika Mlitz, Victoria Kunczer, Emina Halilbasic, Nadja Leditznig, Annika Wahlström, Marcus Ståhlman, Andrea Thüringer, Karl Kashofer, Tatjana Stojakovic, Hanns-Ulrich Marschall, Michael Trauner
Gut - 2018 -
Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in
mice.
Esther Nuñez Durán, Mariam Aghajan, Manoj Amrutkar, Silva Sütt, Emmelie Cansby, Sheri L Booten, Andrew Watt, Marcus Ståhlman, Norbert Stefan, Hans-Ulrich Häring, Harald Staiger, Jan Borén, Hanns-Ulrich Marschall, Margit Mahlapuu
Hepatology communications - 2018 -
Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting
MS
Lenka Novakova, Avadhesh Kumar Singh, Markus Axelsson, Marcus Ståhlman, Martin Adiels, Clas Malmeström, Henrik Zetterberg, Jan Borén, Jan Lycke, Susanna Cardell, Maria K. Blomqvist
Journal of Neurochemistry - 2018 -
Pilot study with IBAT inhibitor A4250 for the treatment of cholestatic pruritus in primary biliary
cholangitis
Samer Al-Dury, Annika Wahlström, S. Wahlin, J. Langedijk, R. O. Elferink, Marcus Ståhlman, Hanns-Ulrich Marschall
Scientific Reports - 2018 -
Reduced obesity, diabetes, and steatosis upon cinnamon and grape pomace are associated with changes in gut microbiota and markers of gut
barrier
M. Van Hul, L. Geurts, H. Plovier, C. Druart, A. Everard, Marcus Ståhlman, M. Rhimi, K. Chira, P. L. Teissedre, N. M. Delzenne, E. Maguin, A. Guilbot, A. Brochot, P. Gerard, Fredrik Bäckhed, P. D. Cani
American Journal of Physiology-Endocrinology and Metabolism - 2018 -
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in
Humans
A. Mardinoglu, Hao Wu, Elias Björnson, C. Zhang, A. Hakkarainen, S. M. Rasanen, S. Lee, Rosellina Margherita Mancina, Mattias Bergentall, K. H. Pietilainen, S. Soderlund, N. Matikainen, Marcus Ståhlman, Per-Olof Bergh, Martin Adiels, B. D. Piening, M. Graner, N. Lundbom, Kevin Jon Williams, Stefano Romeo, J. Nielsen, M. Snyder, M. Uhlen, Göran Bergström, Rosie Perkins, Hanns-Ulrich Marschall, Fredrik Bäckhed, M. R. Taskinen, Jan Borén
Cell Metabolism - 2018 -
Membrane fluidity is regulated by the C-elegans transmembrane protein FLD-1 and its human homologs
TLCD1/2
Mario Ruiz, Rakesh Bodhicharla, Emma Svensk, Ranjan Devkota, Kiran Busayavalasa, Henrik Palmgren, Marcus Ståhlman, Jan Borén, Marc Pilon
eLife - 2018 -
Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus
Deterioration
Björn O. Schröder, George M. H. Birchenough, Marcus Ståhlman, Liisa Arike, Malin E V Johansson, Gunnar C. Hansson, Fredrik Bäckhed
Cell Host & Microbe - 2018 -
Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects
article
K. E. C. Bouter, G. J. Bakker, E. Levin, A. V. Hartstra, R. S. Kootte, S. D. Udayappan, S. Katiraei, L. Bahler, P. W. Gilijamse, V. Tremaroli, Marcus Ståhlman, F. Holleman, N. A. W. Van Riel, H. J. Verberne, J. A. Romijn, G. M. Dallinga-Thie, M. J. Serlie, M. T. Ackermans, E. M. Kemper, K. Willems Van Dijk, F. Backhed, A. K. Groen, M. Nieuwdorp
Clinical and Translational Gastroenterology - 2018 -
Crosstalk between Bile Acids and Gut Microbiota and Its Impact on Farnesoid X Receptor
Signalling
Annika Wahlström, Petia Kovatcheva-Datchary, Marcus Ståhlman, Fredrik Bäckhed, Hanns-Ulrich Marschall
Digestive Diseases - 2017 -
High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and
UPLC-MS/MS
Maria K. Blomqvist, Jan Borén, Henrik Zetterberg, Kaj Blennow, Jan-Eric Månsson, Marcus Ståhlman
Journal of Lipid Research - 2017 -
The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty
acids.
Ranjan Devkota, Emma Svensk, Mario Ruiz, Marcus Ståhlman, Jan Borén, Marc Pilon
PLoS genetics - 2017 -
Network analyses identify liver-specific targets for treating liver
diseases.
Sunjae Lee, Cheng Zhang, Zhengtao Liu, Martina Klevstig, Bani Mukhopadhyay, Mattias Bergentall, Resat Cinar, Marcus Ståhlman, Natasha Sikanic, Joshua K Park, Sumit Deshmukh, Azadeh M Harzandi, Tim Kuijpers, Morten Grøtli, Simon J Elsässer, Brian D Piening, Michael Snyder, Ulf Smith, Jens Nielsen, Fredrik Bäckhed, George Kunos, Mathias Uhlen, Jan Borén, Adil Mardinoglu
Molecular systems biology - 2017 -
Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse
hearts.
Linda Andersson, Christina Drevinge, Ismena Mardani, Knut T Dalen, Marcus Ståhlman, Martina Klevstig, Annika Lundqvist, Fred Haugen, Martin Adiels, Per Fogelstrand, Jorge Asin-Cayuela, Lillemor Mattsson Hultén, Max Levin, Ewa Ehrenborg, Yun K Lee, Alan R Kimmel, Jan Borén, Malin Levin
The international journal of biochemistry & cell biology - 2017 -
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the
drug
Hao Wu, E. Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås Holm, Marcus Ståhlman, Lisa M. Olsson, M. Serino, M. Planas-Felix, G. Xifra, J. M. Mercader, D. Torrents, R. Burcelin, W. Ricart, Rosie Perkins, J. M. Fernandez-Real, Fredrik Bäckhed
Nature Medicine - 2017 -
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated
mice
E. Krones, K. Eller, M. J. Pollheimer, S. Racedo, A. H. Kirsch, B. Frauscher, Annika Wahlström, Marcus Ståhlman, M. Trauner, F. Grahammer, T. B. Huber, K. Wagner, A. R. Rosenkranz, Hanns-Ulrich Marschall, P. Fickert
Journal of Hepatology - 2017 -
Personal model-assisted identification of NAD(+) and glutathione metabolism as intervention target in
NAFLD
A. Mardinoglu, Elias Björnson, C. Zhang, Martina Klevstig, S. Soderlund, Marcus Ståhlman, Martin Adiels, A. Hakkarainen, N. Lundbom, M. Kilicarslan, B. M. Hallstrom, J. Lundbom, B. Verges, P. H. R. Barrett, G. F. Watts, M. J. Serlie, J. Nielsen, M. Uhlen, Ulf Smith, Hanns-Ulrich Marschall, M. R. Taskinen, Jan Borén
Molecular Systems Biology - 2017 -
Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: A randomized controlled
trial
Reza Mobini, Valentina Tremaroli, Marcus Ståhlman, F. Karlsson, Max Levin, Maria Ljungberg, Maja Sohlin, Helene Berteus Forslund, Rosie Perkins, Fredrik Bäckhed, Per-Anders Jansson
Diabetes Obesity & Metabolism - 2017 -
Induction of FXR signaling in germ-free mice colonized with a human
microbiota.
Annika Wahlström, Petia Kovatcheva-Datchary, Marcus Ståhlman, Muhammad Tanweer Khan, Fredrik Bäckhed, Hanns-Ulrich Marschall
Journal of lipid research - 2017 -
Hepatocyte MyD88 affects bile acids, gut microbiota and metabolome contributing to regulate glucose and lipid
metabolism
T. Duparc, H. Plovier, V. G. Marrachelli, M. Van Hul, A. Essaghir, Marcus Ståhlman, S. Matamoros, L. Geurts, M. M. Pardo-Tendero, C. Druart, N. M. Delzenne, J. B. Demoulin, S. W. van der Merwe, J. van Pelt, Fredrik Bäckhed, D. Monleon, A. Everard, P. D. Cani
Gut - 2017 -
Cyp3a11 is not essential for the formation of murine bile
acids
Annika Wahlström, Samer Al-Dury, Marcus Ståhlman, Fredrik Bäckhed, Hanns-Ulrich Marschall
Biochemistry and Biophysics Reports - 2017 -
Microbiota-induced obesity requires farnesoid X
receptor
Ava Parseus, Nina Sommer, Felix Sommer, Robert Caesar, Antonio Molinaro, Marcus Ståhlman, Thomas U. Greiner, Rosie Perkins, Fredrik Bäckhed
Gut - 2017 -
Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal
muscle.
Urszula Chursa, Esther Nuñez Durán, Emmelie Cansby, Manoj Amrutkar, Silva Sütt, Marcus Ståhlman, Britt-Marie Olsson, Jan Borén, Maria Johansson, Fredrik Bäckhed, Bengt R Johansson, Carina Sihlbom, Margit Mahlapuu
Diabetologia - 2017 -
The impact of Roux-en-Y gastric bypass surgery on normal metabolism in a porcine
model
A. Lindqvist, M. Ekelund, E. Garcia-Vaz, Marcus Ståhlman, S. Pierzynowski, M. F. Gomez, J. F. Rehfeld, L. Groop, J. Hedenbro, N. Wierup, P. Spegel
Plos One - 2017 -
Dietary Omega-3 Fatty Acids Increase Survival and Decrease Bacterial Load in Mice Subjected to Staphylococcus aureus-Induced
Sepsis
Sara L Svahn, Marcus A Ulleryd, Louise Grahnemo, Marcus Ståhlman, Jan Borén, Staffan Nilsson, John-Olov Jansson, Maria E Johansson
Infection and Immunity - 2016 -
STK25 is a critical determinant in nonalcoholic
steatohepatitis.
Manoj Amrutkar, Urszula Chursa, Matthias Kern, Esther Nuñez Durán, Marcus Ståhlman, Silva Sütt, Jan Borén, Bengt R Johansson, Hanns-Ulrich Marschall, Matthias Blüher, Margit Mahlapuu
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2016 -
Perilipin 5 is protective in the ischemic
heart
Christina Drevinge, K. T. Dalen, M. N. Mannila, Margareta Scharin Täng, Marcus Ståhlman, Martina Klevstig, Annika Lundqvist, Ismena Mardani, F. Haugen, Per Fogelstrand, Martin Adiels, Jorge Asin-Cayuela, C. Ekestam, J. R. Gadin, Y. K. Lee, H. Nebb, Sara Svedlund, Bengt R Johansson, Lillemor Mattsson Hultén, Stefano Romeo, Björn Redfors, Elmir Omerovic, Max Levin, Li-Ming Gan, P. Eriksson, Linda Andersson, E. Ehrenborg, A. R. Kimmel, Jan Borén, Malin Levin
International Journal of Cardiology - 2016 -
Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold
Exposure
M. Zietak, Petia Kovatcheva-Datchary, L. H. Markiewicz, Marcus Ståhlman, L. P. Kozak, Fredrik Bäckhed
Cell Metabolism - 2016 -
Targeting acid sphingomyelinase reduces cardiac ceramide accumulation in the post-ischemic
heart
Martina Klevstig, Marcus Ståhlman, Annika Lundqvist, Margareta Scharin Täng, Per Fogelstrand, Martin Adiels, Linda Andersson, R. Kolesnick, Anders Jeppsson, Jan Borén, Malin Levin
Journal of Molecular and Cellular Cardiology - 2016 -
A LC-MS-based workflow for measurement of branched fatty acid esters of hydroxy fatty
acids.
Tejia Zhang, Shili Chen, Ismail Syed, Marcus Ståhlman, Matthew J Kolar, Edwin A Homan, Qian Chu, Ulf Smith, Jan Borén, Barbara B Kahn, Alan Saghatelian
Nature Protocols - 2016 -
Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in
humans
Manoj Amrutkar, M. Kern, Esther Nuñez Durán, Marcus Ståhlman, Emmelie Cansby, Urszula Chursa, Elin Stenfeldt, Jan Borén, M. Bluher, Margit Mahlapuu
Diabetologia - 2016 -
Liver receptor homolog-1 is a critical determinant of methyl-pool
metabolism
M. Wagner, S. Choi, K. Panzitt, J. L. Mamrosh, J. M. Lee, A. Zaufel, R. Xiao, R. Wooton-Kee, Marcus Ståhlman, C. B. Newgard, Jan Borén, D. D. Moore
Hepatology - 2016 -
Caenorhabditis elegans PAQR-2 and IGLR-2 protect against glucose toxicity by modulating membrane lipid
composition
Emma Svensk, Ranjan Devkota, Marcus Ståhlman, Parmida Ranji, Manish Rauthan, Fredrik Magnusson, Sofia Hammarsten, Maja Johansson, Jan Borén, Marc Pilon
PLoS Genetics - 2016 -
ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid
metabolism
Aditi Chaudhari, Liliana Håversen, Reza Mobini, Linda Andersson, Marcus Ståhlman, Emma Lu, Mikael Rutberg, Per Fogelstrand, Kim Ekroos, Adil Mardinoglu, Malin Levin, Rosie Perkins, Jan Borén
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids - 2016 -
The BUME method: a new rapid and simple chloroform-free method for total lipid extraction of animal
tissue
Lars Löfgren, G. B. Forsberg, Marcus Ståhlman
Scientific Reports - 2016 -
The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus
arctos
Felix Sommer, Marcus Ståhlman, O. Ilkayeva, J. M. Arnemo, J. Kindberg, J. Josefsson, C. B. Newgard, O. Frobert, Fredrik Bäckhed
Cell Reports - 2016 -
Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing
cholangitis
A. Baghdasaryan, C. D. Fuchs, C. H. Osterreicher, U. J. Lemberger, E. Halilbasic, I. Pahlman, H. Graffner, E. Krones, P. Fickert, Annika Wahlström, Marcus Ståhlman, G. Paumgartner, Hanns-Ulrich Marschall, M. Trauner
Journal of Hepatology - 2016 -
p110alpha hot spot mutations E545K and H1047R exert metabolic reprogramming independently of p110alpha kinase
activity
Aditi Chaudhari, Daniel Krumlinde, Annika Lundqvist, Levent Akyürek, Sashidar Bandaru, Kristina Skålen, Marcus Ståhlman, Jan Borén, Yvonne Wettergren, Katarina Ejeskär, Victoria Rotter Sopasakis
Molecular and Cellular Biology - 2015 -
Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass
Regulation
Valentina Tremaroli, Fredrik H. Karlsson, Malin Werling, Marcus Ståhlman, Petia Kovatcheva-Datchary, Torsten Olbers, Lars Fändriks, Carel W le Roux, Jens B. Nielsen, Fredrik Bäckhed
Cell Metabolism - 2015 -
Atrial fibrillation in patients admitted to coronary care units in western Sweden - focus on obesity and
lipotoxicity.
Sigfus Gizurarson, Marcus Ståhlman, Anders Jeppsson, Yangzhen Shao, Björn Redfors, Lennart Bergfeldt, Jan Borén, Elmir Omerovic
Journal of electrocardiology - 2015 -
Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes
Model
Manoj Amrutkar, Emmelie Cansby, Urszula Chursa, Esther Nuñez Durán, Belén Chanclón, Marcus Ståhlman, Vincent Fridén, Louise Mannerås Holm, Anna Wickman, Ulf Smith, Fredrik Bäckhed, Jan Borén, B. W. Howell, Margit Mahlapuu
Diabetes - 2015 -
Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and
NASH
Manoj Amrutkar, Emmelie Cansby, Esther Nuñez Durán, Carlo Pirazzi, Marcus Ståhlman, Elin Stenfeldt, Ulf Smith, Jan Borén, Margit Mahlapuu
Faseb Journal - 2015 -
Microbiome of prebiotic-treated mice reveals novel targets involved in host response during
obesity
A. Everard, V. Lazarevic, N. Gaia, Maria Johansson, Marcus Ståhlman, Fredrik Bäckhed, N. M. Delzenne, J. Schrenzel, P. Francois, P. D. Cani
Isme Journal - 2014 -
Ceramides are associated with inflammatory processes in human mediastinal adipose
tissue
J. Gertow, S. Kjellqvist, Marcus Ståhlman, L. Cheung, Johan Gottfries, O. Werngren, Jan Borén, A. Franco-Cereceda, P. Eriksson, R. M. Fisher
NMCD. Nutrition Metabolism and Cardiovascular Diseases - 2014 -
Rapid Quantification of Yeast Lipid using Microwave-Assisted Total Lipid Extraction and
HPLC-CAD
Sakda Khoomrung, Pramote Chumnanpuen, Suwanee Jansa-Ard, Marcus Ståhlman, Intawat Nookaew, Jan Borén, Jens B. Nielsen
Analytical Chemistry - 2013 -
Zfp148 Deficiency Causes Lung Maturation Defects and Lethality in Newborn Mice That Are Rescued by Deletion of p53 or Antioxidant
Treatment
Volkan I. Sayin, Anna Nilton, Mohamed X Ibrahim, Pia Ågren, Erik Larsson, Marleen MR Petit, Lillemor Mattsson Hultén, Marcus Ståhlman, Bengt R Johansson, Martin Bergö, Per Lindahl
Plos One - 2013 -
Targeting GGTase-I Activates RHOA, Increases Macrophage Reverse Cholesterol Transport, and Reduces Atherosclerosis in
Mice
Omar M. Khan, Murali K Akula, Kristina Skålen, Christin Karlsson, Marcus Ståhlman, S. G. Young, Jan Borén, Martin Bergö
Circulation - 2013 -
Cholesteryl Esters Accumulate in the Heart in a Porcine Model of Ischemia and
Reperfusion
Christina Drevinge, Lars O Karlsson, Marcus Ståhlman, Thomas Larsson, Jeanna Perman Sundelin, Lars Grip, Linda Andersson, Jan Borén, Malin Levin
Plos One - 2013 -
Dyslipidemia, but not hyperglycemia and insulin resistance, is associated with marked alterations in the HDL lipidome in type 2 diabetic subjects in the DIWA cohort: Impact on small HDL
particles
Marcus Ståhlman, Björn Fagerberg, Martin Adiels, K. Ekroos, J. M. Chapman, A. Kontush, Jan Borén
Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids - 2013 -
PAQR-2 Regulates Fatty Acid Desaturation during Cold Adaptation in C.
elegans
Emma Svensk, Marcus Ståhlman, Carl-Henrik Andersson, Maja Johansson, Jan Borén, Marc Pilon
Plos Genetics - 2013 -
ARF6 Regulates Neuron Differentiation through Glucosylceramide
Synthase
Lu Li, Marcus Ståhlman, Mikael Rutberg, Liliana Håversen, Per Fogelstrand, Linda Andersson, Malin Levin, Jan Borén
Plos One - 2013 -
A mouse model reveals an important role for catecholamine-induced lipotoxicity in the pathogenesis of stress-induced
cardiomyopathy.
Yangzhen Shao, Björn Redfors, Marcus Ståhlman, Margareta Scharin Täng, Azra Miljanovic, Helge Möllmann, Christian Troidl, Sebastian Szardien, Christian Hamm, Holger Nef, Jan Borén, Elmir Omerovic
European journal of heart failure - 2013 -
Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in
vitro
Carlo Pirazzi, Martin Adiels, Maria Antonella Burza, Rosellina Margherita Mancina, Malin Levin, Marcus Ståhlman, M. R. Taskinen, M. Orho-Melander, Jeanna Perman, A. Pujia, Linda Andersson, Cristina Maglio, T. Montalcini, Olov Wiklund, Jan Borén, Stefano Romeo
Journal of Hepatology - 2012 -
Clinical dyslipidaemia is associated with changes in the lipid composition and inflammatory properties of apolipoprotein-B-containing lipoproteins from women with type 2
diabetes.
Marcus Ståhlman, H T Pham, Martin Adiels, T W Mitchell, S J Blanksby, Björn Fagerberg, Kim Ekroos, Jan Borén
Diabetologia - 2012 -
Increased Expression of the Very Low-Density Lipoprotein Receptor Mediates Lipid Accumulation in Clear-Cell Renal Cell
Carcinoma
Jeanna Perman Sundelin, Marcus Ståhlman, Annika Lundqvist, Max Levin, P. Parini, Martin Johansson, Jan Borén
Plos One - 2012 -
The Importance of GLUT3 for De Novo Lipogenesis in Hypoxia-Induced Lipid Loading of Human
Macrophages
Lu Li, Bo Liu, Liliana Håversen, Emma Lu, Lisa U. Magnusson, Marcus Ståhlman, Jan Borén, Göran Bergström, Malin Levin, Lillemor Mattsson Hultén
Plos One - 2012 -
The BUME method: a novel automated chloroform-free 96-well total lipid extraction method for blood
plasma
L. Lofgren, Marcus Ståhlman, G. B. Forsberg, S. Saarinen, R. Nilsson, G. I. Hansson
Journal of Lipid Research - 2012 -
Rip2 deficiency leads to increased atherosclerosis despite decreased
inflammation.
Malin Levin, Pernilla Jirholt, Anna Wramstedt, Maria E Johansson, Anna M Lundberg, Maria Gustafsson Trajkovska, Marcus Ståhlman, Per Fogelstrand, Mikael Brisslert, Linda Fogelstrand, Zhong-Qun Yan, Göran K Hansson, Harry Björkbacka, Sven-Olof Olofsson, Jan Borén
Circulation research - 2011 -
The VLDL receptor promotes lipotoxicity and increases mortality in mice following an acute myocardial
infarction.
Jeanna Perman, Pontus Boström, Malin Lindbom, Ulf Lidberg, Marcus Ståhlman, Daniel Hägg, Henrik Lindskog, Margareta Scharin Täng, Elmir Omerovic, Lillemor Mattsson Hultén, Anders Jeppsson, Petur Petursson, Johan Herlitz, Gunilla Olivecrona, Dudley K Strickland, Kim Ekroos, Sven-Olof Olofsson, Jan Borén
The Journal of clinical investigation - 2011 -
LDL-associated apolipoprotein J and lysozyme are associated with atherogenic properties of LDL found in type 2 diabetes and the metabolic
syndrome.
Camilla Pettersson, H Karlsson, Marcus Ståhlman, Thomas Larsson, Björn Fagerberg, Mats Lindahl, Olov Wiklund, Jan Borén, Linda Fogelstrand
Journal of internal medicine - 2011 -
Establishment of a transgenic mouse model specifically expressing human serum amyloid a in adipose
tissue.
Maja Olsson, Sofie Ahlin, Bob Olsson, Per-Arne Svensson, Marcus Ståhlman, Jan Borén, Lena M S Carlsson, Kajsa Sjöholm
PloS one - 2011 -
Studies of atherogenic lipoproteins using mass spectrometry-based
lipidomics
Marcus Ståhlman
2010 -
High-throughput shotgun lipidomics by quadrupole time-of-flight mass
spectrometry.
Marcus Ståhlman, CS Ejsing, K Tarasov, Jeanna Perman, Jan Borén, K Ekroos
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences - 2009 -
ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase and Increased binding to
Biglycan.
A Hiukka, Marcus Ståhlman, Camilla Pettersson, Malin Levin, Martin Adiels, Susann Teneberg, ES Leinonen, Lillemor Mattsson Hultén, Olov Wiklund, M Oresic, Sven-Olof Olofsson, MR Taskinen, K Ekroos, Jan Borén
Diabetes - 2009 -
ApoCIII-enriched LDL in type 2 diabetes displays altered lipid composition and increased susceptibility for
sphingomyelinase
Anne Hiukka, Marcus Ståhlman, Camilla Pettersson, Malin Levin, Martin Adiels, Susann Teneberg, Olov Wiklund, Matej Oresic, Sven-Olof Olofsson, Marja-Riitta Taskinen, Kim Ekroos, Jan Borén
CHEMISTRY AND PHYSICS OF LIPIDS - 2008 -
Proteomics and lipids of lipoproteins isolated at low salt concentrations in D2O/sucrose or in
KBr.
Marcus Ståhlman, Pia Davidsson, Ida Kanmert, Birgitta Rosengren, Jan Borén, Björn Fagerberg, German Camejo
Journal of lipid research - 2008 -
Hypoxia converts human macrophages into triglyceride-loaded foam
cells.
Pontus Boström, Björn Magnusson, Per-Arne Svensson, Olov Wiklund, Jan Borén, Lena M S Carlsson, Marcus Ståhlman, Sven-Olof Olofsson, Lillemor Mattsson Hultén
Arteriosclerosis, thrombosis, and vascular biology - 2006