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Haiqiang Dou
Researcher
Department of Physiology-
Loss of electrical β-cell to δ-cell coupling underlies impaired hypoglycaemia-induced glucagon secretion in type-1
diabetes
Thomas G. Hill, Rui Gao, Anna Benrick, Lakshmi Kothegala, Nils Rorsman, Cristiano Santos, Samuel Acreman, Linford J. Briant, Haiqiang Dou, Nikhil Gandasi, Claudia Guida, Elizabeth Haythorne, Marsha Wallace, Jakob G. Knudsen, Caroline Miranda, Johan Tolö, Anne Clark, Lucy Davison, Joachim Storling, Andrei Tarasov, Frances M. Ashcroft, Patrik Rorsman, Quan Zhang
NATURE METABOLISM - 2024 -
Glucose Controls Glucagon Secretion by Regulating Fatty Acid Oxidation in Pancreatic
α-Cells
Sarah L. Armour, Alexander Frueh, Margarita V. Chibalina, Haiqiang Dou, Lidia Argemi-Muntadas, Alexander Hamilton, Georgios Katzilieris-Petras, Peter Carmeliet, Benjamin Davies, Thomas Moritz, Lena Eliasson, Patrik Rorsman, Jakob G. Knudsen
DIABETES - 2023 -
A critical role of the mechanosensor PIEZO1 in glucose-induced insulin secretion in pancreatic
beta-cells
Y. Y. Ye, M. Barghouth, Haiqiang Dou, C. Luan, Y. Z. Wang, A. Karagiannopoulos, X. P. Jiang, U. Krus, M. Fex, Q. Zhang, L. Eliasson, Patrik Rorsman, E. M. Zhang, E. Renstrom
Nature Communications - 2022 -
Nanoscale Amperometry Reveals that Only a Fraction of Vesicular Serotonin Content is Released During Exocytosis from Beta
Cells
Amir Hatamie, Lin Ren, Haiqiang Dou, Nikhil Gandasi, Patrik Rorsman, Andrew G Ewing
Angewandte Chemie-International Edition - 2021 -
'Resistance is futile?' - paradoxical inhibitory effects of K-ATP channel closure in glucagon-secreting
alpha-cells
Q. Zhang, Haiqiang Dou, Patrik Rorsman
Journal of Physiology - 2020 -
Gs/Gq signaling switch in beta cells defines incretin effectiveness in
diabetes
O. S. Oduori, N. Murao, K. Shimomura, H. Takahashi, Q. Zhang, Haiqiang Dou, S. Sakai, K. Minami, Belén Chanclón, C. Guida, Lakshmi Kothegala, Johan Tolö, Y. Maejima, N. Yokoi, Y. Minami, T. Miki, Patrik Rorsman, S. Seino
Journal of Clinical Investigation - 2020 -
A method for the generation of human stem cell-derived alpha
cells
Q. P. Peterson, A. Veres, L. H. Chen, M. Q. Slama, J. H. R. Kenty, S. Hassoun, M. R. Brown, Haiqiang Dou, C. D. Duffy, Q. Zhou, A. V. Matveyenko, Björn Tyrberg, M. Sorhede-Winzell, Patrik Rorsman, D. A. Melton
Nature Communications - 2020 -
GLP-1 suppresses glucagon secretion in human pancreatic alpha-cells by inhibition of P/Q-type Ca2+
channels
R. Ramracheya, C. Chapman, M. Chibalina, Haiqiang Dou, Caroline Miranda, A. Gonzalez, Y. Moritoh, M. Shigeto, Q. Zhang, M. Braun, A. Clark, P. R. Johnson, Patrik Rorsman, L. J. B. Briant
Physiological Reports - 2018