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- Louise Mannerås Holm
Louise Mannerås Holm
Researcher
Department of Molecular and Clinical Medicine-
Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and
torpor.
Linda Engström-Ruud, Ferran Font Gironès, Joanna Zajdel, Lara Kern, Júlia Teixidor-Deulofeu, Louise Mannerås Holm, Alba Carreras, Barbara Becattini, Andreas Björefeldt, Eric Hanse, Henning Fenselau, Giovanni Solinas, Jens C Brüning, Thomas F Wunderlich, Fredrik Bäckhed, Johan Ruud
Cell reports - 2024 -
Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved
metabolism
E. Belda, L. Voland, Valentina Tremaroli, G. Falony, S. Adriouch, K. E. Assmann, E. Prifiti, J. Aron-Wisnewsky, J. Debedat, T. Le Roy, T. Nielsen, C. Amouyal, S. Andre, F. Andreelli, M. Bluher, R. Chakaroun, J. Chilloux, L. P. Coelho, M. C. Dao, P. Das, S. Fellahi, S. Forslund, N. Galleron, T. H. Hansen, B. Holmes, B. Y. Ji, H. K. Pedersen, P. Le, E. Le Chatelier, C. Lewinter, Louise Mannerås Holm, F. Marquet, A. Myridakis, V. Pelloux, N. Pons, B. Quinquis, C. Rouault, H. Roume, J. E. Salem, N. Sokolovska, N. B. Sondertoft, S. Touch, S. Vieira-Silva, P. Galan, J. Holst, J. P. Gotze, L. Kober, H. Vestergaard, T. Hansen, S. Hercberg, J. M. Oppert, J. Nielsen, I. Letunic, M. E. Dumas, M. Stumvoll, O. B. Pedersen, P. Bork, S. D. Ehrlich, J. D. Zucker, Fredrik Bäckhed, J. Raes, K. Clement
Gut - 2022 -
Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host
health
T. P. N. Bui, Louise Mannerås Holm, R. Puschmann, Hao Wu, A. D. Troise, B. Nijsse, S. Boeren, Fredrik Bäckhed, D. Fiedler, W. M. deVos
Nature Communications - 2021 -
The gut microbiota regulates hypothalamic inflammation and leptin sensitivity in Western diet-fed mice via a GLP-1R-dependent
mechanism
Christina Heiss, Louise Mannerås Holm, Ying Shiuan Lee, Julia Serrano-Lobo, Anna Håkansson-Gladh, R. J. Seeley, D. J. Drucker, Fredrik Bäckhed, Louise Olofsson
Cell Reports - 2021 -
Microbial Imidazole Propionate Affects Responses to Metformin through p38 gamma-Dependent Inhibitory AMPK
Phosphorylation
Ara Koh, Louise Mannerås Holm, N. O. Yunn, P. M. Nilsson, S. H. Ryu, Antonio Molinaro, Rosie Perkins, J. Gustav Smith, Fredrik Bäckhed
Cell Metabolism - 2020 -
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through
mTORC1
Ara Koh, Antonio Molinaro, Marcus Ståhlman, Muhammad Tanweer Khan, Caroline Schmidt, Louise Mannerås Holm, Hao Wu, Alba Carreras, Louise Olofsson, Per-Olof Bergh, V. Gerdes, A. Hartstra, M. de Brauw, Rosie Perkins, Max Nieuwdorp, Göran Bergström, Fredrik Bäckhed
Cell - 2018 -
Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin
networks
Filipe De Vadder, Estelle Grasset, Louise Mannerås Holm, G. Karsenty, A. J. Macpherson, Louise Olofsson, Fredrik Bäckhed
Proceedings of the National Academy of Sciences of the United States of America - 2018 -
Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the
drug
Hao Wu, E. Esteve, Valentina Tremaroli, Muhammad Tanweer Khan, Robert Caesar, Louise Mannerås Holm, Marcus Ståhlman, Lisa M. Olsson, M. Serino, M. Planas-Felix, G. Xifra, J. M. Mercader, D. Torrents, R. Burcelin, W. Ricart, Rosie Perkins, J. M. Fernandez-Real, Fredrik Bäckhed
Nature Medicine - 2017 -
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin
resistance.
John Grünberg, Jenny M Hoffmann, Shahram Hedjazifar, Annika Nerstedt, Lachmi E Jenndahl, Johannes Elvin, John Castellot, Lan Wei, Sofia Movérare-Skrtic, Claes Ohlsson, Louise Mannerås Holm, Fredrik Bäckhed, Ismail Syed, Fatima Bosch, Alan Saghatelian, Barbara B Kahn, Ann Hammarstedt, Ulf Smith
Scientific reports - 2017 -
Host–microbiota interaction induces bi-phasic inflammation and glucose intolerance in
mice
Antonio Molinaro, Robert Caesar, Louise Mannerås Holm, Valentina Tremaroli, P. D. Cani, Fredrik Bäckhed
Molecular Metabolism - 2017 -
Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db
mice
Shanthadevi Udayappan, Louise Mannerås Holm, Alice Chaplin-Scott, Clara Belzer, Hilde Herrema, Geesje M. Dallinga-Thie, Silvia H. Duncan, Erik S.G. Stroes, Albert K. Groen, Harry J. Flint, Fredrik Bäckhed, Willem M. De Vos, Max Nieuwdorp
npj Biofilms and Microbiomes - 2016 -
Genetic Disruption of Protein Kinase STK25 Ameliorates Metabolic Defects in a Diet-Induced Type 2 Diabetes
Model
Manoj Amrutkar, Emmelie Cansby, Urszula Chursa, Esther Nuñez Durán, Belén Chanclón, Marcus Ståhlman, Vincent Fridén, Louise Mannerås Holm, Anna Wickman, Ulf Smith, Fredrik Bäckhed, Jan Borén, B. W. Howell, Margit Mahlapuu
Diabetes - 2015 -
Enhanced insulin sensitivity and acute regulation of metabolic genes and signaling pathways after a single electrical or manual acupuncture session in female insulin-resistant
rats.
Anna Benrick, Manuel Maliqueo, Julia Johansson, Miao Sun, Xiaoke Wu, Louise Mannerås Holm, Elisabet Stener-Victorin
Acta Diabetologica - 2014 -
Gene expression in subcutaneous adipose tissue differs in women with polycystic ovary syndrome and controls matched pair-wise for age, body weight, and body mass
index.
Louise Mannerås Holm, Anna Benrick, Elisabet Stener-Victorin
Adipocyte - 2014 -
Electrical vs Manual Acupuncture Stimulation in a Rat Model of Polycystic Ovary Syndrome: Different Effects on Muscle and Fat Tissue Insulin
Signaling
Julia Johansson, Louise Mannerås Holm, Linus Ruijin Shao, AnneLiese Magnusson-Olsson, Malin Lönn, Håkan Billig, Elisabet Stener-Victorin
PLOS ONE - 2013 -
Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat
diet.
Emmelie Cansby, Manoj Amrutkar, Louise Mannerås Holm, Annika Nerstedt, Azadeh Reyahi, Elin Stenfeldt, Jan Borén, Peter Carlsson, Ulf Smith, Juleen R Zierath, Margit Mahlapuu
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2013 -
Labisia pumila Upregulates Peroxisome Proliferator-Activated Receptor Gamma Expression in Rat Adipose Tissues and 3T3-L1
Adipocytes.
Fazliana Mansor, Harvad Gu, Claes-Göran Östensson, Louise Mannerås Holm, Elisabet Stener-Victorin, WN WNWan Mohamud
Advances in Pharmacological Sciences - 2013 -
Effects of acupuncture and exercise on insulin sensitivity, adipose tissue characteristics, and markers of coagulation and fibrinolysis in women with polycystic ovary syndrome: secondary analyses of a randomized controlled
trial.
Elisabet Stener-Victorin, Baghaei F, Göran Holm, Per-Olof Janson, G Olivecrona, Malin Lönn, Louise Mannerås Holm
Fertility and Sterility - 2012 -
Electrical and manual acupuncture stimulation affect oestrous cyclicity and neuroendocrine function in an 5α-dihydrotestosterone-induced rat polycystic ovary syndrome
model.
Yi Feng, Julia Johansson, Louise Mannerås Holm, Linus Ruijin Shao, Håkan Billig, Elisabet Stener-Victorin
Experimental physiology - 2012 -
Adipose tissue has aberrant morphology and function in PCOS: enlarged adipocytes and low serum adiponectin, but not circulating sex steroids, are strongly associated with insulin
resistance.
Louise Mannerås Holm, Henrik Leonhardt, Joel Kullberg, Eva Jennische, Anders Odén, Göran Holm, Mikael Hellström, Lars Lönn, Gunilla Olivecrona, Elisabet Stener-Victorin, Malin Lönn
The Journal of clinical endocrinology and metabolism - 2011 -
Coagulation and Fibrinolytic Disturbances in Women with Polycystic Ovary
Syndrome.
Louise Mannerås Holm, Fariba Baghaei, Göran Holm, Per-Olof Janson, Claes Ohlsson, Malin Lönn, Elisabet Stener-Victorin
The Journal of clinical endocrinology and metabolism - 2011 -
Beneficial metabolic effects of the Malaysian herb Labisia pumila var. alata in a rat model of polycystic ovary
syndrome.
Louise Mannerås, M Fazliana, W M Wan Nazaimoon, Malin Lönn, H F Gu, C G Ostenson, Elisabet Stener-Victorin
Journal of ethnopharmacology - 2010 -
Polycystic ovary syndrome – Studies of metabolic and ovarian disturbances and effects of physical exercise and
electro-acupuncture
Louise Mannerås Holm
2010 -
Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency
electro-acupuncture.
Yi Feng, Julia Johansson, Linus Ruijin Shao, Louise Mannerås, Julia Fernandez-Rodriguez, Håkan Billig, Elisabet Stener-Victorin
PloS one - 2009 -
Acupuncture and exercise restore adipose tissue expression of sympathetic markers and improve ovarian morphology in rats with dihydrotestosterone-induced
PCOS.
Louise Mannerås, Stefan Cajander, Malin Lönn, Elisabet Stener-Victorin
American journal of physiology. Regulatory, integrative and comparative physiology - 2009 -
Acupuncture in Polycystic Ovary Syndrome: Current Experimental and Clinical
Evidence.
Elisabet Stener-Victorin, Elizabeth Jedel, Louise Mannerås
Journal of Neuroendocrinology - 2008 -
Low-frequency electro-acupuncture and physical exercise improve metabolic disturbances and modulate gene expression in adipose tissue in rats with dihydrotestosterone-induced polycystic ovary
syndrome.
Louise Mannerås, Ingibjörg H Jonsdottir, Agneta Holmäng, Malin Lönn, Elisabet Stener-Victorin
Endocrinology - 2008 -
Serotonin transporter gene polymorphisms: Effect on serotonin transporter availability in the brain of suicide
attempters.
Jessica Bah Rösman, Mats Lindström, Lars Westberg, Louise Mannerås, Erik Ryding, Susanne Henningsson, Jonas Melke, Ingmar Rosén, Lil Träskman-Bendz, Elias Eriksson
Psychiatry research - 2008 -
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary
syndrome.
Louise Mannerås, Stefan Cajander, Agneta Holmäng, Zamira Seleskovic, Ted Lystig, Malin Lönn, Elisabet Stener-Victorin
Endocrinology - 2007 -
Maternal taurine supplementation in the late pregnant rat stimulates postnatal growth and induces obesity and insulin resistance in adult
offspring
Karin Hultman, Camilla Alexanderson, Louise Mannerås, Mats Sandberg, Agneta Holmäng, Thomas Jansson
J Physiol - 2007