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Magnus Sabel
Affiliated to Research
Department of PediatricsAbout Magnus Sabel
Magnus Sabel is a senior consultant Pediatric Oncologist at the Queen Silvia Children´s Hospital, Sahlgrenska University Hospital and a researcher at the Sahlgrenska Academy, University of Gothenburg. Magnus does research in Pediatric Oncology, especially neuro-oncology.
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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort
study.
Ayse Bahar Ercan, Melyssa Aronson, Nicholas R Fernandez, Yuan Chang, Adrian Levine, Zhihui Amy Liu, Logine Negm, Melissa Edwards, Vanessa Bianchi, Lucie Stengs, Jiil Chung, Abeer Al-Battashi, Agnes Reschke, Alex Lion, Alia Ahmad, Alvaro Lassaletta, Alyssa T Reddy, Amir F Al-Darraji, Amish C Shah, An Van Damme, Anne Bendel, Aqeela Rashid, Ashley S Margol, Bethany L Kelly, Bojana Pencheva, Brandie Heald, Brianna Lemieux-Anglin, Bruce Crooks, Carl Koschmann, Catherine Gilpin, Christopher C Porter, David Gass, David Samuel, David S Ziegler, Deborah T Blumenthal, Dennis John Kuo, Dima Hamideh, Donald Basel, Dong-Anh Khuong-Quang, Duncan Stearns, Enrico Opocher, Fernando Carceller, Hagit Baris Feldman, Helen Toledano, Ira Winer, Isabelle Scheers, Ivana Fedorakova, Jack M Su, Jaime Vengoechea, Jaroslav Sterba, Jeffrey Knipstein, Jordan R Hansford, Julieta Rita Gonzales-Santos, Kanika Bhatia, Kevin J Bielamowicz, Khurram Minhas, Kim E Nichols, Kristina A Cole, Lynette Penney, Magnus Aasved Hjort, Magnus Sabel, Maria Joao Gil-da-Costa, Matthew J Murray, Matthew Miller, Maude L Blundell, Maura Massimino, Maysa Al-Hussaini, Mazin F Al-Jadiry, Melanie A Comito, Michael Osborn, Michael P Link, Michal Zapotocky, Mithra Ghalibafian, Najma Shaheen, Naureen Mushtaq, Nicolas Waespe, Nobuko Hijiya, Noemi Fuentes-Bolanos, Olfat Ahmad, Omar Chamdine, Paromita Roy, Pavel N Pichurin, Per Nyman, Rachel Pearlman, Rebecca C Auer, Reghu K Sukumaran, Rejin Kebudi, Rina Dvir, Robert Raphael, Ronit Elhasid, Rose B McGee, Rose Chami, Ryan Noss, Ryuma Tanaka, Salmo Raskin, Santanu Sen, Scott Lindhorst, Sebastien Perreault, Shani Caspi, Shazia Riaz, Shlomi Constantini, Sophie Albert, Stanley Chaleff, Stefan Bielack, Stefano Chiaravalli, Stuart Louis Cramer, Sumita Roy, Suzanne Cahn, Suzanne Penna, Syed Ahmer Hamid, Tariq Ghafoor, Uzma Imam, Valerie Larouche, Vanan Magimairajan Issai, William D Foulkes, Yi Yen Lee, Paul C Nathan, Yosef E Maruvka, Mary-Louise C Greer, Carol Durno, Adam Shlien, Birgit Ertl-Wagner, Anita Villani, David Malkin, Cynthia Hawkins, Eric Bouffet, Anirban Das, Uri Tabori
The Lancet Oncology - 2024 -
Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors-a nationwide, prospective Swedish
study.
Bianca Tesi, Kristina Lagerstedt Robinson, Frida Abel, Teresita Díaz de Ståhl, Sara Orrsjö, Anna Poluha, Maria Hellberg, Sandra Wessman, Sofie Samuelsson, Tony Frisk, Hartmut Vogt, Karin Henning, Magnus Sabel, Torben Ek, Niklas Pal, Per Nyman, Geraldine Giraud, Joakim Wille, Cornelis Jan Pronk, Ulrika Norén-Nyström, Magnus Borssén, Maria Fili, Gustav Stålhammar, Nikolas Herold, Giorgio Tettamanti, Carolina Maya-Gonzalez, Linda Arvidsson, Anna Rosén, Katja Ekholm, Ekaterina Kuchinskaya, Anna-Lotta Hallbeck, Margareta Nordling, Pia Palmebäck, Per Kogner, Gunilla Kanter Smoler, Päivi Lähteenmäki, Susanne Fransson, Tommy Martinsson, Alia Shamik, Fredrik Mertens, Richard Rosenquist, Valtteri Wirta, Emma Tham, Pernilla Grillner, Johanna Sandgren, Gustaf Ljungman, David Gisselsson, Fulya Taylan, Ann Nordgren
The Lancet regional health. Europe - 2024 -
Combined immunotherapy improves outcome for replication repair deficient (RRD) high-grade glioma failing anti-PD1 monotherapy: A report from the International RRD
Consortium.
Anirban Das, Nicholas R Fernandez, Adrian Levine, Vanessa Bianchi, Lucie K Stengs, Jiil Chung, Logine Negm, Jose Rafael Dimayacyac, Yuan Chang, Liana Nobre, Ayse B Ercan, Santiago Sanchez-Ramirez, Sumedha Sudhaman, Melissa Edwards, Valerie Larouche, David Samuel, An Van Damme, David Gass, David S Ziegler, Stefan S Bielack, Carl Koschmann, Shayna Zelcer, Michal Yalon-Oren, Gadi Abede Campino, Tomasz Sarosiek, Kim E Nichols, Rebecca Loret De Mola, Kevin Bielamowicz, Magnus Sabel, Charlotta A Frojd, Matthew D Wood, Jason M Glover, Yi-Yen Lee, Magimairajan Vanan, Jenny K Adamski, Sebastien Perreault, Omar Chamdine, Magnus Aasved Hjort, Michal Zapotocky, Fernando Carceller, Erin Wright, Ivana Fedorakova, Alexander Lossos, Ryuma Tanaka, Michael Osborn, Deborah T Blumenthal, Melyssa Aronson, Ute Bartels, Annie Huang, Vijay Ramaswamy, David Malkin, Adam Shlien, Anita Villani, Peter B Dirks, Trevor J Pugh, Gad Getz, Yosef E Maruvka, Derek S Tsang, Birgit Ertl-Wagner, Cynthia Hawkins, Eric Bouffet, Daniel A Morgenstern, Uri Tabori
Cancer discovery - 2024 -
Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With
Cancer.
Elisabeth Wadensten, Sandra Wessman, Frida Abel, Teresita Diaz De Ståhl, Bianca Tesi, Christina Orsmark Pietras, Linda Arvidsson, Fulya Taylan, Susanne Fransson, Hartmut Vogt, Anna Poluha, Sailendra Pradhananga, Maria Hellberg, Kristina Lagerstedt-Robinson, Praveen Raj Somarajan, Sofie Samuelsson, Sara Orrsjö, Khurram Maqbool, Karin Henning, Tobias Strid, Torben Ek, Henrik Fagman, Thomas Olsson Bontell, Tommy Martinsson, Florian Puls, Per Kogner, Valtteri Wirta, Cornelis Jan Pronk, Joakim Wille, Richard Rosenquist, Monica Nistér, Fredrik Mertens, Magnus Sabel, Ulrika Norén-Nyström, Pernilla Grillner, Ann Nordgren, Gustaf Ljungman, Johanna Sandgren, David Gisselsson
JCO Precision Oncology (JCO PO) - 2023 -
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in
Sweden
Teresita Díaz de Ståhl, Alia Shamikh, Markus Mayrhofer, Szilvester Juhos, Elisa Basmaci, Gabriela Prochazka, Maxime Garcia, Praveen Raj Somarajan, Katarzyna Zielinska-Chomej, Ingrid Øra, Peter Siesjö, Per Erik Sandström, Jakob Stenman, Magnus Sabel, Bengt Gustavsson, Per Kogner, Susan Pfeifer, Gustaf Ljungman, Johanna Sandgren, Monica Nistér
Journal of Translational Medicine - 2023 -
Sustained Survival Benefit in Recurrent Medulloblastoma by a Metronomic Antiangiogenic Regimen: A Nonrandomized Controlled
Trial.
Andreas Peyrl, Monika Chocholous, Magnus Sabel, Alvaro Lassaletta, Jaroslav Sterba, Pierre Leblond, Karsten Nysom, Ingrid Torsvik, Susan N Chi, Thomas Perwein, Neil Jones, Stefan Holm, Per Nyman, Helena Mörse, Anders Öberg, Liesa Weiler-Wichtl, Ulrike Leiss, Christine Haberler, Maresa T Schmook, Lisa Mayr, Karin Dieckmann, Marcel Kool, Johannes Gojo, Amedeo A Azizi, Nicolas André, Mark Kieran, Irene Slavc
JAMA oncology - 2023 -
Supratentorial CNS-PNETs in children; a Swedish population-based study with molecular re-evaluation and long-term
follow-up
Elizabeth Schepke, Maja Löfgren, T. Pietsch, Teresia Kling, C. Nordborg, Thomas Olsson Bontell, S. Holm, A. Oberg, P. Nyman, M. Eliasson-Hofvander, Magnus Sabel, Birgitta Lannering, Helena Caren
Clinical Epigenetics - 2023 -
Novel TPR::ROS1 Fusion Gene Activates MAPK, PI3K and JAK/STAT Signaling in an Infant-type Pediatric
Glioma.
Lily Deland, Simon Keane, Thomas Olsson Bontell, Henrik Fagman, Helene Sjögren, Anders E Lind, Helena Caren, Magnus Tisell, Jonas A Nilsson, Katarina Ejeskär, Magnus Sabel, Frida Abel
Cancer genomics & proteomics - 2022 -
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair
deficiency
A. Das, S. Sudhaman, D. Morgenstern, A. Coblentz, J. Chung, S. C. Stone, N. Alsafwani, Z. A. Liu, O. A. A. Karsaneh, S. Soleimani, H. Ladany, D. Chen, M. Zatzman, V. Cabric, L. Nobre, V. Bianchi, M. Edwards, L. C. Sambira Nahum, A. B. Ercan, A. Nabbi, S. Constantini, R. Dvir, M. Yalon-Oren, G. A. Campino, S. Caspi, V. Larouche, A. Reddy, M. Osborn, G. Mason, S. Lindhorst, A. Bronsema, V. Magimairajan, E. Opocher, R. L. De Mola, Magnus Sabel, C. Frojd, D. Sumerauer, D. Samuel, K. Cole, S. Chiaravalli, M. Massimino, P. Tomboc, D. S. Ziegler, B. George, A. Van Damme, N. Hijiya, D. Gass, R. B. McGee, O. Mordechai, D. C. Bowers, T. W. Laetsch, A. Lossos, D. T. Blumenthal, T. Sarosiek, L. Y. Yen, J. Knipstein, A. Bendel, L. M. Hoffman, S. Luna-Fineman, S. Zimmermann, I. Scheers, K. E. Nichols, M. Zapotocky, J. R. Hansford, J. M. Maris, P. Dirks, M. D. Taylor, A. V. Kulkarni, M. Shroff, D. S. Tsang, A. Villani, W. Xu, M. Aronson, C. Durno, A. Shlien, D. Malkin, G. Getz, Y. E. Maruvka, P. S. Ohashi, C. Hawkins, T. J. Pugh, E. Bouffet, U. Tabori
Nature Medicine - 2022 -
Prospective registration of symptoms and times to diagnosis in children and adolescents with central nervous system tumors: A study of the Swedish Childhood Cancer
Registry
O. Rask, F. Nilsson, P. Lahteenmaki, C. Ehrstedt, S. Holm, P. E. Sandstrom, P. Nyman, Magnus Sabel, P. Grillner, C. N. S. Tumor Workin Swedish Childhood
Pediatric Blood & Cancer - 2022 -
DNA methylation profiling improves routine diagnosis of paediatric central nervous system tumours: A prospective population-based
study
Elizabeth Schepke, Maja Löfgren, T. Pietsch, Thomas Olsson Bontell, Teresia Kling, Anna Wenger, Sandra Ferreyra Vega, Anna Danielsson, Sandor Dosa, S. Holm, A. Oberg, P. Nyman, M. Eliasson-Hofvander, P. E. Sandstrom, S. M. Pfister, Birgitta Lannering, Magnus Sabel, Helena Caren
Neuropathology and Applied Neurobiology - 2022 -
Survival Benefit for Individuals With Constitutional Mismatch Repair Deficiency Undergoing
Surveillance
C. Durno, A. B. Ercan, V. Bianchi, M. Edwards, M. Aronson, M. Galati, E. G. Atenafu, G. Abebe-Campino, A. Al-Battashi, M. Alharbi, V. F. Azad, H. N. Baris, D. Basel, R. Bedgood, A. Bendel, S. Ben-Shachar, D. T. Blumenthal, M. Blundell, M. Bornhorst, A. Bronsema, E. Cairney, S. Rhode, S. Caspi, A. Chamdin, S. Chiaravalli, S. Constantini, B. Crooks, A. Das, R. Dvir, R. Farah, W. D. Foulkes, Z. Frenkel, B. Gallinger, S. Gardner, D. Gass, M. Ghalibafian, C. Gilpin, Y. Goldberg, C. Goudie, S. A. Hamid, H. Hampel, J. R. Hansford, C. Harlos, N. Hijiya, S. Hsu, J. Kamihara, R. Kebudi, J. Knipstein, C. Koschmann, C. Kratz, V. Larouche, A. Lassaletta, S. Lindhorst, S. C. Ling, M. P. Link, R. L. De Mola, R. Luiten, M. Lurye, J. L. Maciaszek, V. MagimairajanIssai, O. M. Maher, M. Massimino, R. B. McGee, N. Mushtaq, G. Mason, M. Newmark, G. Nicholas, K. E. Nichols, T. Nicolaides, E. Opocher, M. Osborn, B. Oshrine, R. Pearlman, D. Pettee, J. Rapp, M. Rashid, A. Reddy, L. Reichman, M. Remke, G. Robbins, S. Roy, Magnus Sabel, D. Samuel, I. Scheers, K. W. Schneider, S. Sen, D. Stearns, D. Sumerauer, C. Swallow, L. Taylor, G. Thomas, H. Toledano, P. Tomboc, A. Van Damme, I. Winer, M. Yalon, L. Y. Yen, M. Zapotocky, S. Zelcer, D. S. Ziegler, S. Zimmermann, C. Hawkins, D. Malkin, E. Bouffet, A. Villani, U. Tabori
Journal of Clinical Oncology - 2021 -
Discovery of a rare GKAP1-NTRK2 fusion in a pediatric low-grade glioma, leading to targeted treatment with TRK-inhibitor
larotrectinib.
Lily Deland, Simon Keane, Thomas Olsson Bontell, Helene Sjögren, Henrik Fagman, Ingrid Øra, Esther De La Cuesta, Magnus Tisell, Jonas A Nilsson, Katarina Ejeskär, Magnus Sabel, Frida Abel
Cancer biology & therapy - 2021 -
Outcomes of BRAF V600E pediatric gliomas treated with targeted BRAF
inhibition
Liana Nobre, Michal Zapotocky, Vijay Ramaswamy, Scott Ryall, Julie Bennett, Daniel Alderete, Julia Balaguer Guill, Lorena Baroni, Ute Bartels, Abhishek Bavle, Miriam Bornhorst, Daniel R. Boue, Adela Canete, Murali Chintagumpala, Scott L. Coven, Ofelia Cruz, Sonika Dahiya, Peter Dirks, Ira J. Dunkel, David Eisenstat, Cecile Faure Conter, Elizabeth Finch, Jonathan L. Finlay, Didier Frappaz, Maria Luisa Garre, Karen Gauvain, Anne Grete Bechensteen, Jordan R. Hansford, Inga Harting, Peter Hauser, Lili Naz Hazrati, Annie Huang, Sarah G. Injac, Valentina Iurilli, Matthias Karajannis, Gurcharanjeet Kaur, Martin Kyncl, Lenka Krskova, Normand Laperriere, Valerie Larouche, Alvaro Lassaletta, Sarah Leary, Frank Lin, Samantha Mascelli, Tara McKeown, Till Milde, Andres Morales la Madrid, Giovanni Morana, Helena Morse, Naureen Mushtaq, Diana S. Osorio, Roger Packer, Zdenek Pavelka, Eduardo Quiroga-Cantero, James Rutka, Magnus Sabel, Duarte Salgado, Palma Solano, Jaroslav Sterba, Jack Su, David Sumerauer, Michael D. Taylor, Helen Toledano, Derek S. Tsang, Mariana Valente Fernandes, Frank van Landeghem, Cornelis M. van Tilburg, Bev Wilson, Olaf Witt, Josef Zamecnik, Eric Bouffet, Cynthia Hawkins, Uri Tabori
JCO Precision Oncology - 2020 -
An integrative radiological, histopathological and molecular analysis of pediatric pontine histone-wildtype glioma with MYCN amplification
(HGG-MYCN)
A. Tauziède-Espariat, M. A. Debily, D. Castel, J. Grill, S. Puget, Magnus Sabel, K. Blomgren, A. Gareton, V. Dangouloff-Ros, E. Lechapt, N. Boddaert, P. Varlet
Acta neuropathologica communications - 2019 -
Cell line-based xenograft mouse model of paediatric glioma stem cells mirrors the clinical course of the
patient
Susanna Larsson, Anna Wenger, S. Dosa, Magnus Sabel, Teresia Kling, Helena Carén
Carcinogenesis - 2018 -
A new GTF2I-BRAF fusion mediating MAPK pathway activation in pilocytic
astrocytoma
Tajana Tesan, Josefin Olausson, Annica Wilzén, Magnus Sabel, Katarina Truvé, H. Sjogren, S. Dosa, Birgitta Lannering, F. Enlund, Tommy Martinsson, Pierre Åman, Frida Abel
PLOS ONE - 2017 -
Effects of physically active video gaming on cognition and activities of daily living in childhood brain tumor survivors: a randomized pilot
study
Magnus Sabel, Anette Sjölund, Jurgen Broeren, Daniel Arvidsson, Jean-Michel Saury, Jonas Gillenstrand, Ingrid Emanuelson, Klas Blomgren, Birgitta Lannering
Neuro Oncology Practice - 2017 -
Hypothermia after cranial irradiation protects neural progenitor cells in the subventricular zone but not in the
hippocampus.
Magnus Sabel, Marie Kalm, Thomas Björk-Eriksson, Birgitta Lannering, Klas Blomgren
International journal of radiation biology - 2017 -
Stem cell cultures derived from pediatric brain tumors accurately model the originating
tumors.
Anna Wenger, Susanna Larsson, Anna Danielsson, Kirstine Juul Elbæk, Petronella Kettunen, Magnus Tisell, Magnus Sabel, Birgitta Lannering, Claes Nordborg, Elizabeth Schepke, Helena Carén
Oncotarget - 2017 -
Comprehensive Analysis of Hypermutation in Human
Cancer
Brittany B. Campbell, Nicholas Light, David Fabrizio, Matthew Zatzman, Fabio Fuligni, Richard de Borja, Scott Davidson, Melissa Edwards, Julia A. Elvin, Karl P. Hodel, Walter J. Zahurancik, Zucai Suo, Tatiana Lipman, Katharina Wimmer, Christian P. Kratz, Daniel C. Bowers, Theodore W. Laetsch, Gavin P. Dunn, Tanner M. Johanns, Matthew R. Grimmer, Ivan V. Smirnov, Valérie Larouche, David Samuel, Annika Bronsema, Michael Osborn, Duncan Stearns, Pichai Raman, Kristina A. Cole, Phillip B. Storm, Michal Yalon, Enrico Opocher, Gary Mason, Gregory A. Thomas, Magnus Sabel, Ben George, David S. Ziegler, Scott Lindhorst, Vanan Magimairajan Issai, Shlomi Constantini, Helen Toledano, Ronit Elhasid, Roula Farah, Rina Dvir, Peter Dirks, Annie Huang, Melissa A. Galati, Jiil Chung, Vijay Ramaswamy, Meredith S. Irwin, Melyssa Aronson, Carol Durno, Michael D. Taylor, Gideon Rechavi, John M. Maris, Eric Bouffet, Cynthia Hawkins, Joseph F. Costello, M. Stephen Meyn, Zachary F. Pursell, David Malkin, Uri Tabori, Adam Shlien
Cell - 2017 -
Active video gaming improves body coordination in survivors of childhood brain
tumours.
Magnus Sabel, Anette Sjölund, Jurgen Broeren, Daniel Arvidsson, Jean-Michel Saury, Klas Blomgren, Birgitta Lannering, Ingrid Emanuelson
Disability and rehabilitation - 2016 -
Stability of patient-derived in vitro cultures of stem-like cells from high-grade paediatric brain
tumours.
Susanna Larsson, Anna Danielsson, Anna Wenger, Magnus Tisell, Magnus Sabel, Birgitta Lannering, Elizabeth Schepke, Helena Carén
Neuro-Oncology - 2016 -
Relapse patterns and outcome after relapse in standard risk medulloblastoma: a report from the HIT-SIOP-PNET4
study
Magnus Sabel, G. Fleischhack, S. Tippelt, G. Gustafsson, F. Doz, R. Kortmann, M. Massimino, A. Navajas, K. von Hoff, S. Rutkowski, M. Warmuth-Metz, S.C. Clifford, T. Pietsch, B. Pizer, Birgitta Lannering
Journal of Neuro-Oncology - 2016 -
MethPed: a DNA methylation classifier tool for the identification of pediatric brain tumor
subtypes
Anna Danielsson, Szilard Nemes, Magnus Tisell, Birgitta Lannering, Claes Nordborg, Magnus Sabel, Helena Carén
Clinical Epigenetics - 2015 -
Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic
lymphohistiocytosis
B. Tesi, K. Lagerstedt-Robinson, S. C. C. Chiang, E. Ben Bdira, M. Abboud, B. Belen, O. Devecioglu, Z. Fadoo, A. E. J. Yeoh, H. C. Erichsen, M. Mottonen, H. H. Akar, J. Hastbacka, Z. Kaya, S. Nunes, T. Patiroglu, Magnus Sabel, E. T. Saribeyoglu, T. H. Tvedt, E. Unal, S. Unal, A. Unuvar, M. Meeths, J. I. Henter, M. Nordenskjold, Y. T. Bryceson
Genome Medicine - 2015 -
Incidence and clinical presentation of primary hemophagocytic lymphohistiocytosis in
Sweden.
Marie Meeths, AnnaCarin Horne, Magnus Sabel, Yenan T Bryceson, Jan-Inge Henter
Pediatric blood & cancer - 2015 -
Detection of IL-17A-producing peripheral blood monocytes in Langerhans cell histiocytosis
patients
M. Lourda, S. Olsson-Akefeldt, D. Gavhed, S. Bjornfot, N. Clausen, U. Hjalmars, Magnus Sabel, A. Tazi, M. Arico, C. Delprat, J. I. Henter, M. Svensson
Clinical Immunology - 2014 -
Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine
production
S. C. C. Chiang, J. Theorell, M. Entesarian, M. Meeths, M. Mastafa, W. Al-Herz, P. Frisk, K. C. Gilmour, M. Ifversen, Cecilia Langenskiöld, M. Machaczka, A. Naqvi, J. Payne, A. Perez-Martinez, Magnus Sabel, E. Unal, S. Unal, J. Winiarski, M. Nordenskjold, H. G. Ljunggren, J. I. Henter, Y. T. Bryceson
Blood - 2013 -
Familial hemophagocytic lymphohistiocytosis type 3 (FHL3) caused by deep intronic mutation and inversion in
UNC13D
M Meeths, SCC Chiang, SM Wood, M Entesarian, H Schlums, B Bang, E Nordenskjold, C Bjorklund, G Jakovljevic, J Jazbec, H Hasle, BM Holmqvist, L Rajic, S Pfeifer, S Rosthoj, Magnus Sabel, TT Salmi, T Stokland, J Winiarski, HG Ljunggren, B Fadeel, M Nordenskjold, JI Henter, YT Bryceson
Blood - 2011