The GraviD study - a prospective population-based cohort in southwestern Sweden
Short description
Its primary focus is to elucidate the D-vitamin status in pregnant individuals and study the association between D-vitamin status and the risk of developing pregnancy-induced hypertension. The study was conducted in collaboration with primary care and all midwifery clinics in Södra Älvsborg, Södra Bohuslän, and Göteborg. Between 2013 and 2014, a total of 2125 pregnant individuals were recruited and followed longitudinally throughout their pregnancies.
One significant advantage of the GraviD study is that it successfully recruited both foreign-born and pregnant individuals across all levels of education. All recruitment occurred during routine maternal health visits, facilitating the establishment of a population-based cohort.
During pregnancy, blood samples were collected in the first and third trimesters, along with questionnaire responses related to background information such as education, origin, dietary intake, supplement use, and sun exposure. Additionally, journal data from pregnancy and childbirth were collected, and data from child health records were obtained. The study investigated D-vitamin status and its relationship with the risk of developing pregnancy-induced hypertension and preeclampsia. Furthermore, researchers explored how diet and background factors were associated with weight gain during pregnancy.
In collaboration with Folkhelseinstituttet and the Norwegian Mother, Father, and Child Cohort Study (MoBa), the GraviD study also examined how D-vitamin status in pregnant individuals was related to children’s growth and the risk of developing overweight and obesity. The children born within the GraviD study and their families were further followed up in the GraviD-child project.
Below are links to articles and theses. Linnea Brembeck defended her thesis in 2017 using data from the GraviD study, and Anna Amberntsson defended her thesis in 2023 using data from the GraviD study and MoBa.