Ulrika Clarhed: Work exposure and obesity linked to chronic rhinosinusitis
Chronic rhinosinusitis causes nasal congestion, runny nose, and impaired sense of smell over long periods. Ulrika Clarhed’s research shows that certain occupational exposures and obesity increase the risk of developing the disease.
ULRIKA CLARHED
Dissertation defense: 14 March 2025 (click for details)
Doctoral thesis: Chronic rhinosinusitis – Epidemiological studies on occupational exposure, obesity and sick leave
Research area: Otorhinolaryngology
Sahlgrenska Academy, The Institute of Clinical Sciences
Chronic rhinosinusitis (CRS) involves more than three months of persistent nasal congestion, facial pain, and reduced sense of smell.
The condition affects quality of life and increases the risk of depression and sleep disturbances. There is currently no cure—only symptomatic treatment.
Ulrika Clarhed has investigated which factors increase the risk of developing CRS and how sick leave differs among affected individuals.
Work exposure and obesity raise risk
What factors influence the risk of developing CRS?
“We found that certain occupational exposures, such as cleaning agents, hair care products, super glue, strong acids, cooking fumes, and wood dust, were linked to a higher risk of developing the disease. Women who work with cleaning agents appear to be particularly vulnerable,” says Ulrika Clarhed, an ear, nose, and throat specialist at Capio Lundby Specialist Hospital and a doctoral student at the Institute of Clinical Sciences.
Obesity (BMI of 30 or higher) was also associated with an increased likelihood of developing CRS.
Sick leave higher in CRS patients
The study shows that CRS patients take more sick leave than those without the disease.
“This trend is particularly evident among women with CRS. We need to better understand these patterns to improve support and treatment. I hope our research can help raise awareness of how occupational factors contribute to CRS,” says Ulrika Clarhed.
A challenge to find research time
What have been the most rewarding and challenging parts of the doctoral project?
“It has been incredibly rewarding to delve into this field and collaborate with skilled colleagues. Discussing and exchanging ideas has been a highlight of the research process. But, like many things in life, finding time for research has sometimes been a challenge.”
Text: Jakob Lundberg