Claes Dahlgren

Function and regulation of GPR84 in human neutrophils

Huamei Forsman, Claes Dahlgren, Jonas Mårtensson, Lena Björkman, Martina Sundqvist
British Journal of Pharmacology - 2024

Larixol is not an inhibitor of Gα<inf>i</inf> containing G proteins and lacks effect on signaling mediated by human neutrophil expressed formyl peptide receptors

Lena Björkman, Huamei Forsman, Linda Bergqvist, Claes Dahlgren, Martina Sundqvist
Biochemical Pharmacology - 2024

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

Stephen P. H. Alexander, Arthur Christopoulos, Anthony P. Davenport, Eamonn Kelly, Alistair A. Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Jamie A. Davies, Maria Pia Abbracchio, George Abraham, Alexander Agoulnik, Wayne Alexander, Khaled Al-hosaini, Magnus Baeck, Jillian G. Baker, Nicholas M. Barnes, Ross Bathgate, Jean-Martin Beaulieu, Annette G. Beck-Sickinger, Maik Behrens, Kenneth E. Bernstein, Bernhard Bettler, Nigel J. M. Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Braeuner-Osborne, Geoffrey Burnstock, Girolamo Calo, Justo P. Castano, Kevin J. Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H. Clapp, Rejean Couture, Helen M. Cox, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Steven D. Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J. Filardo, Tung Fong, Marta Fumagalli, Raul R. Gainetdinov, Michael L. Garelja, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L. Goodfriend, Cyril Goudet, Lukas Graetz, Karen J. Gregory, Andrew L. Gundlach, Joerg Hamann, Julien Hanson, Richard L. Hauger, Debbie L. Hay, Akos Heinemann, Deron Herr, Morley D. Hollenberg, Nicholas D. Holliday, Mastgugu Horiuchi, Daniel Hoyer, Laszlo Hunyady, Ahsan Husain, Adriaan P. Ijzerman, Tadashi Inagami, Kenneth A. Jacobson, Robert T. Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans-Juergen Kreienkamp, Jyrki P. Kukkonen, Tobias Langenhan, Dan Larhammar, Katie Leach, Davide Lecca, John D. Lee, Susan E. Leeman, Jerome Leprince, Xaria X. Li, Stephen J. Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Davide Malfacini, Jean Mazella, Craig A. Mcardle, Shlomo Melmed, Martin C. Michel, Laurence J. Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E. Mueller, Philip M. Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G. Pertwee, Jean-Philippe Pin, Eric R. Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K. Reinscheid, Philippe Rondard, G. Enrico Rovati, Chiara Ruzza, Gareth J. Sanger, Torsten Schoeneberg, Gunnar Schulte, Stefan Schulz, Deborah L. Segaloff, Charles N. Serhan, Khuraijam Dhanachandra Singh, Craig M. Smith, Leigh A. Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P. Tan, David Thal, Walter ( Wally) Thomas, Pieter B. M. W. M. Timmermans, Kalyan Tirupula, Lawrence Toll, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S. Walker, Ji Ming Wang, Donald T. Ward, Hans-Juergen Wester, Gary B. Willars, Tom Lloyd Williams, Trent M. Woodruff, Chengcan Yao, Richard D. Ye
BRITISH JOURNAL OF PHARMACOLOGY - 2023

The allosterically modulated FFAR2 is transactivated by signals generated by other neutrophil GPCRs

Simon Lind, K. L. Granberg, Huamei Forsman, Claes Dahlgren
Plos One - 2023

The ketone body acetoacetate activates human neutrophils through FFAR2.

Jonas Mårtensson, Lena Björkman, Simon Lind, Moa Viklund, Linjie Zhang, Saray Gutierrez, Claes Dahlgren, Martina Sundqvist, Xin Xie, Huamei Forsman
Journal of leukocyte biology - 2023

An increase in the cytosolic concentration of free calcium ions activates the neutrophil NADPH-oxidase provided that the free fatty acid receptor 2 has been allosterically modulated.

Simon Lind, Yanling Wu, Martina Sundqvist, Huamei Forsman, Claes Dahlgren
Cellular signalling - 2023

AZ2158 is a more potent formyl peptide receptor 1 inhibitor than the commonly used peptide antagonists in abolishing neutrophil chemotaxis.

Huamei Forsman, Yanling Wu, Jonas Mårtensson, Lena Björkman, Kenneth L Granberg, Claes Dahlgren, Martina Sundqvist
Biochemical pharmacology - 2023

Structural Determinants in the Staphylococcus aureus-Derived Phenol-Soluble Modulin α2 Peptide Required for Neutrophil Formyl Peptide Receptor Activation

Moa Viklund, Johanna Fredriksson, André Holdfeldt, Simon Lind, H. Franzyk, Claes Dahlgren, Martina Sundqvist, Huamei Forsman
Journal of Immunology - 2022

G protein coupled pattern recognition receptors expressed in neutrophils: Recognition, activation/modulation, signaling and receptor regulated functions.

Claes Dahlgren, Simon Lind, Jonas Mårtensson, Lena Björkman, Yanling Wu, Martina Sundqvist, Huamei Forsman
Immunological reviews - 2022

Phenol-soluble modulin α and β display divergent roles in mice with staphylococcal septic arthritis.

Zhicheng Hu, Pradeep Kumar Kopparapu, Patrick Ebner, Majd Mohammad, Simon Lind, Anders Jarneborn, Claes Dahlgren, Michelle Schultz, Megshree Deshmukh, Rille Pullerits, Mulugeta Nega, Minh-Thu Nguyen, Ying Fei, Huamei Forsman, Friedrich Götz, Tao Jin
Communications biology - 2022

GRK2 selectively attenuates the neutrophil NADPH-oxidase response triggered by beta-arrestin recruiting GPR84 agonists

Johanna Fredriksson, André Holdfeldt, Jonas Mårtensson, Lena Björkman, T. C. Moller, E. Mullers, Claes Dahlgren, Martina Sundqvist, Huamei Forsman
Biochimica Et Biophysica Acta-Molecular Cell Research - 2022

Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far?

N. H. Schebb, H. Kuehn, A. S. Kahnt, K. M. Rund, V. B. O'Donnell, N. Flamand, M. Peters-Golden, P. J. Jakobsson, K. H. Weylandt, N. Rohwer, R. C. Murphy, G. Geisslinger, G. A. FitzGerald, J. Hanson, Claes Dahlgren, M. W. Alnouri, S. Offermanns, D. Steinhilber
Frontiers in Pharmacology - 2022

Allosteric receptor modulation uncovers an FFA2R antagonist as a positive orthosteric modulator/agonist in disguise.

Simon Lind, Dagny Olofsson Hoffmann, Huamei Forsman, Claes Dahlgren
Cellular signalling - 2021

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.

Arthur Christopoulos, Stephen Ph Alexander, Anthony P Davenport, Eamonn Kelly, Alistair Mathie, John A Peters, Emma L Veale, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Christopher Southan, Jamie A Davies, Maria Pia Abbracchio, Wayne Alexander, Khaled Al-Hosaini, Magnus Bäck, Nicholas M Barnes, Ross Bathgate, Jean-Martin Beaulieu, Kenneth E Bernstein, Bernhard Bettler, Nigel J M Birdsall, Victoria Blaho, Francois Boulay, Corinne Bousquet, Hans Bräuner-Osborne, Geoffrey Burnstock, Girolamo Caló, Justo P Castaño, Kevin J Catt, Stefania Ceruti, Paul Chazot, Nan Chiang, Bice Chini, Jerold Chun, Antonia Cianciulli, Olivier Civelli, Lucie H Clapp, Réjean Couture, Zsolt Csaba, Claes Dahlgren, Gordon Dent, Khuraijam Dhanachandra Singh, Steven D Douglas, Pascal Dournaud, Satoru Eguchi, Emanuel Escher, Edward J Filardo, Tung Fong, Marta Fumagalli, Raul R Gainetdinov, Marc de Gasparo, Craig Gerard, Marvin Gershengorn, Fernand Gobeil, Theodore L Goodfriend, Cyril Goudet, Karen J Gregory, Andrew L Gundlach, Jörg Hamann, Julien Hanson, Richard L Hauger, Debbie L Hay, Akos Heinemann, Morley D Hollenberg, Nicholas D Holliday, Mastgugu Horiuchi, Daniel Hoyer, László Hunyady, Ahsan Husain, Adriaan P IJzerman, Tadashi Inagami, Kenneth A Jacobson, Robert T Jensen, Ralf Jockers, Deepa Jonnalagadda, Sadashiva Karnik, Klemens Kaupmann, Jacqueline Kemp, Charles Kennedy, Yasuyuki Kihara, Takio Kitazawa, Pawel Kozielewicz, Hans-Jürgen Kreienkamp, Jyrki P Kukkonen, Tobias Langenhan, Katie Leach, Davide Lecca, John D Lee, Susan E Leeman, Jérôme Leprince, Xaria X Li, Tom Lloyd Williams, Stephen J Lolait, Amelie Lupp, Robyn Macrae, Janet Maguire, Jean Mazella, Craig A McArdle, Shlomo Melmed, Martin C Michel, Laurence J Miller, Vincenzo Mitolo, Bernard Mouillac, Christa E Müller, Philip Murphy, Jean-Louis Nahon, Tony Ngo, Xavier Norel, Duuamene Nyimanu, Anne-Marie O'Carroll, Stefan Offermanns, Maria Antonietta Panaro, Marc Parmentier, Roger G Pertwee, Jean-Philippe Pin, Eric R Prossnitz, Mark Quinn, Rithwik Ramachandran, Manisha Ray, Rainer K Reinscheid, Philippe Rondard, G Enrico Rovati, Chiara Ruzza, Gareth J Sanger, Torsten Schöneberg, Gunnar Schulte, Stefan Schulz, Deborah L Segaloff, Charles N Serhan, Leigh A Stoddart, Yukihiko Sugimoto, Roger Summers, Valerie P Tan, David Thal, Walter Wally Thomas, Pieter B M W M Timmermans, Kalyan Tirupula, Giovanni Tulipano, Hamiyet Unal, Thomas Unger, Celine Valant, Patrick Vanderheyden, David Vaudry, Hubert Vaudry, Jean-Pierre Vilardaga, Christopher S Walker, Ji Ming Wang, Donald T Ward, Hans-Jürgen Wester, Gary B Willars, Trent M Woodruff, Chengcan Yao, Richard D Ye
British journal of pharmacology - 2021

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids.

Agnes Dahlstrand Rudin, Arsham Khamzeh, Vignesh Venkatakrishnan, Tishana Persson, Michael Gabl, Otto Savolainen, Huamei Forsman, Claes Dahlgren, Karin Christenson, Johan Bylund
Frontiers in cellular and infection microbiology - 2021

Multiple ligand recognition sites in free fatty acid receptor 2 (FFA2R) direct distinct neutrophil activation patterns.

Simon Lind, André Holdfeldt, Jonas Mårtensson, Kenneth L Granberg, Huamei Forsman, Claes Dahlgren
Biochemical pharmacology - 2021

Neutrophil Signaling That Challenges Dogmata of G Protein-Coupled Receptor Regulated Functions

Claes Dahlgren, André Holdfeldt, Simon Lind, Jonas Mårtensson, Michael Gabl, Lena Björkman, Martina Sundqvist, Huamei Forsman
ACS Pharmacology and Translational Science - 2020

The PAR4-derived pepducin P4Pal10 lacks effect on neutrophil GPCRs that couple to Gαq for signaling but distinctly modulates function of the Gαi-coupled FPR2 and FFAR2

André Holdfeldt, Simon Lind, Camilla Hesse, Claes Dahlgren, Huamei Forsman
Biochemical Pharmacology - 2020

Barbadin selectively modulates FPR2-mediated neutrophil functions independent of receptor endocytosis

Martina Sundqvist, André Holdfeldt, S. C. Wright, T. C. Moller, Esther Siaw, K. Jennbacken, H. Franzyk, M. Bouvier, Claes Dahlgren, Huamei Forsman
Biochimica Et Biophysica Acta-Molecular Cell Research - 2020

Interdependent allosteric free fatty acid receptor 2 modulators synergistically induce functional selective activation and desensitization in neutrophils

Simon Lind, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, T. P. Kenakin, Lena Björkman, Huamei Forsman, Claes Dahlgren
Biochimica Et Biophysica Acta-Molecular Cell Research - 2020

Data showing effects of a PI3K-delta inhibitor on neutrophil superoxide production during FPR2 activation and reactivation

André Holdfeldt, Martina Sundqvist, Claes Dahlgren, Huamei Forsman
Data in Brief - 2020

Measurement of Respiratory Burst Products, Released or Retained, During Activation of Professional Phagocytes.

Claes Dahlgren, Halla Björnsdottir, Martina Sundqvist, Karin Christenson, Johan Bylund
Methods in molecular biology (Clifton, N.J.) Vol 2087. - 2020

Intracellular neutrophil oxidants: From laboratory curiosity to clinical reality

Claes Dahlgren, Anna Karlsson, Johan Bylund
Journal of Immunology - 2019

Functional selective ATP receptor signaling controlled by the free fatty acid receptor 2 through a novel allosteric modulation mechanism.

Simon Lind, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, Lena Björkman, Huamei Forsman, Claes Dahlgren
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 2019

Identification of Residues Critical for FPR2 Activation by the Cryptic Peptide Mitocryptide-2 Originating from the Mitochondrial DNA-Encoded Cytochrome b.

Simon Lind, Michael Gabl, André Holdfeldt, Jonas Mårtensson, Martina Sundqvist, Kodai Nishino, Claes Dahlgren, Hidehito Mukai, Huamei Forsman
Journal of immunology (Baltimore, Md. : 1950) - 2019

DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils.

Alicia Buck, Felix P Klose, Vignesh Venkatakrishnan, Claes Dahlgren, Karin Christenson, Johan Bylund
ImmunoHorizons - 2019

Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

Q. Liu, Martina Sundqvist, W. Y. Li, André Holdfeldt, L. Zhang, Lena Björkman, Johan Bylund, Claes Dahlgren, C. Wang, X. D. Zhao, Huamei Forsman
Bmc Pediatrics - 2019

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949

Simon Lind, Martina Sundqvist, R. Holmdahl, Claes Dahlgren, Huamei Forsman, P. Olofsson
Biochemical Pharmacology - 2019

Neutrophil recruitment to inflamed joints can occur without cellular priming.

Lena Björkman, Karin Christenson, Lisa Davidsson, Jonas Mårtensson, Firoozeh Amirbeagi, Amanda Welin, Huamei Forsman, Anna Karlsson, Claes Dahlgren, Johan Bylund
Journal of leukocyte biology - 2019

Staphylococcus aureus-Derived PSMα Peptides Activate Neutrophil FPR2 but Lack the Ability to Mediate β-Arrestin Recruitment and Chemotaxis.

Martina Sundqvist, Karin Christenson, André Holdfeldt, Karin Jennbacken, Thor C Møller, Claes Dahlgren, Huamei Forsman
Journal of immunology - 2019

Structure-Function Characteristics and Signaling Properties of Lipidated Peptidomimetic FPR2 Agonists: Peptoid Stereochemistry and Residues in the Vicinity of the Headgroup Affect Function

André Holdfeldt, S. L. Skovbakke, Michael Gabl, C. Nielsen, Claes Dahlgren, H. Franzyk, Huamei Forsman
ACS Omega - 2019

Neutrophil priming that turns natural FFA2R agonists into potent activators of the superoxide generating NADPH-oxidase

Jonas Mårtensson, André Holdfeldt, Martina Sundqvist, Michael Gabl, T. P. Kenakin, Lena Björkman, Huamei Forsman, Claes Dahlgren
Journal of leukocyte biology - 2018

Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties.

Michael Gabl, Martina Sundqvist, André Holdfeldt, Simon Lind, Jonas Mårtensson, Karin Christenson, Takayuki Marutani, Claes Dahlgren, Hidehito Mukai, Huamei Forsman
Journal of immunology - 2018

Formyl Peptide Receptors in Mice and Men: Similarities and Differences in Recognition of Conventional Ligands and Modulating Lipopeptides.

Malene Winther, Claes Dahlgren, Huamei Forsman
Basic & clinical pharmacology & toxicology - 2018

Martina Sundqvist, Karin Christenson, André Holdfeldt, Michael Gabl, Jonas Mårtensson, Lena Björkman, Regis Dieckmann, Claes Dahlgren, Huamei Forsman
Biochimica et biophysica acta - 2018

FPR2 signaling without β-arrestin recruitment alters the functional repertoire of neutrophils.

Michael Gabl, André Holdfeldt, Martina Sundqvist, Jalal Lomei, Claes Dahlgren, Huamei Forsman
Biochemical pharmacology - 2017

Elevated Mitochondrial Reactive Oxygen Species and Cellular Redox Imbalance in Human NADPH-Oxidase-Deficient Phagocytes

Martina Sundqvist, Karin Christenson, Halla Björnsdottir, Veronica Osla, Anna Karlsson, Claes Dahlgren, D. P. Speert, Anders Fasth, K. L. Brown, Johan Bylund
Frontiers in Immunology - 2017

Phenol-Soluble Modulin α Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway.

Halla Björnsdottir, Agnes Dahlstrand Rudin, Felix P Klose, Jonas Elmwall, Amanda Welin, Marios Stylianou, Karin Christenson, Constantin F Urban, Huamei Forsman, Claes Dahlgren, Anna Karlsson, Johan Bylund
Frontiers in immunology - 2017

Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question

Malene Winther, André Holdfeldt, Martina Sundqvist, Zahra Rajabkhani, Michael Gabl, Johan Bylund, Claes Dahlgren, Huamei Forsman
Plos One - 2017

Combining Elements from Two Antagonists of Formyl Peptide Receptor 2 Generates More Potent Peptidomimetic Antagonists.

Sarah Line Skovbakke, André Holdfeldt, Christina Nielsen, Anna Mette Hansen, Iris Perez-Gassol, Claes Dahlgren, Huamei Forsman, Henrik Franzyk
Journal of medicinal chemistry - 2017

Reactivation of Gαi-coupled formyl peptide receptors is inhibited by Gαq-selective inhibitors when induced by signals generated by the platelet-activating factor receptor.

André Holdfeldt, Agnes Dahlstrand Rudin, Michael Gabl, Zahra Rajabkhani, Gabriele M König, Evi Kostenis, Claes Dahlgren, Huamei Forsman
Journal of Leukocyte Biology - 2017

Formylated MHC Class lb Binding Peptides Activate Both Human and Mouse Neutrophils Primarily through Formyl Peptide Receptor 1

Malene Winther, André Holdfeldt, Michael Gabl, J. M. Wang, Huamei Forsman, Claes Dahlgren
PLoS ONE - 2016

The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment

Lena Björkman, Jonas Martensson, Malene Winther, Michael Gabl, André Holdfeldt, Martin Uhrbom, Johan Bylund, A. H. Hansen, S. K. Pandey, T. Ulven, Huamei Forsman, Claes Dahlgren
Molecular and Cellular Biology - 2016

The lipidated peptidomimetic Lau-[(S)-Aoc]-(Lys-βNphe)6-NH2 is a novel formyl peptide receptor 2 agonist that activates both human and mouse neutrophil NADPH-oxidase.

André Holdfeldt, Sarah Line Skovbakke, Malene Winther, Michael Gabl, Christina Nielsen, Iris Perez-Gassol, Camilla Josephine Larsen, Ji Ming Wang, Anna Karlsson, Claes Dahlgren, Huamei Forsman, Henrik Franzyk
The Journal of biological chemistry - 2016

A pepducin designed to modulate P2Y2R function interacts with FPR2 in human neutrophils and transfers ATP to an NADPH-oxidase-activating ligand through a receptor cross-talk mechanism.

Michael Gabl, André Holdfeldt, Malene Winther, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Biochimica et biophysica acta - 2016

Quantification of heterotypic granule fusion in human neutrophils by imaging flow cytometry.

Halla Björnsdottir, Amanda Welin, Claes Dahlgren, Anna Karlsson, Johan Bylund
Data in brief - 2016

The peptidomimetic Lau-(Lys-βNSpe)6-NH2 antagonizes formyl peptide receptor 2 expressed in mouse neutrophils.

Sarah Line Skovbakke, Malene Winther, Michael Gabl, André Holdfeldt, Sara K. Lindén, Ji Ming Wang, Claes Dahlgren, Henrik Franzyk, Huamei Forsman
Biochemical pharmacology - 2016

Data on human neutrophil activation induced by pepducins with amino acid sequences derived from β2AR and CXCR4.

André Holdfeldt, Malene Winther, Michael Gabl, Claes Dahlgren, Huamei Forsman
Data in brief - 2016

Basic characteristics of the neutrophil receptors that recognize formylated peptides, a danger-associated molecular pattern generated by bacteria and mitochondria.

Claes Dahlgren, Michael Gabl, André Holdfeldt, Malene Winther, Huamei Forsman
Biochemical pharmacology - 2016

P2Y2 receptor signaling in neutrophils Is regulated from inside by a novel cytoskeleton-dependent mechanism.

Michael Gabl, Malene Winther, Amanda Welin, Anna Karlsson, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Experimental cell research - 2015

The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.

Sarah Line Skovbakke, Peter M H Heegaard, Camilla J Larsen, Henrik Franzyk, Huamei Forsman, Claes Dahlgren
Biochemical pharmacology - 2015

Neutrophil NET formation is regulated from the inside by myeloperoxidase-processed reactive oxygen species.

Halla Björnsdottir, Amanda Welin, Erik Michaëlsson, Veronica Osla, Stefan Berg, Karin Christenson, Martina Sundqvist, Claes Dahlgren, Anna Karlsson, Johan Bylund
Free radical biology & medicine - 2015

A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead

Malene Winther, Michael Gabl, Amanda Welin, Claes Dahlgren, Huamei Forsman
Febs Letters - 2015

CFP-10 from Mycobacterium tuberculosis Selectively Activates Human Neutrophils through a Pertussis Toxin-Sensitive Chemotactic Receptor.

Amanda Welin, Halla Björnsdottir, Malene Winther, Karin Christenson, Tudor I Oprea, Anna Karlsson, Huamei Forsman, Claes Dahlgren, Johan Bylund
Infection and immunity - 2015

Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.

Huamei Forsman, Malene Winther, Michael Gabl, Sarah Line Skovbakke, Francois Boulay, Marie-Josèphe Rabiet, Claes Dahlgren
Biochimica et biophysica acta - 2015

Olfactomedin-4 autoantibodies give unusual c-ANCA staining patterns with reactivity to a subpopulation of neutrophils.

Firoozeh Amirbeagi, Pontus Thulin, Rille Pullerits, Bo Pedersen, Bengt A. Andersson, Claes Dahlgren, Amanda Welin, Johan Bylund
Journal of leukocyte biology - 2015

Collection of in vivo transmigrated neutrophils from human skin.

Karin Christenson, Lena Björkman, Lisa Davidsson, Anna Karlsson, Per Follin, Claes Dahlgren, Johan Bylund
Methods in molecular biology (Clifton, N.J.) - 2014

Turning Chemoattractant Receptors On and Off with Conventional Ligands and Allosteric Modulators: Recent advances in formyl peptide receptor signaling and regulation

Johan Bylund, Michael Gabl, Malene Winther, Karin Önnheim, Claes Dahlgren, Huamei Forsman
Inflammation and cell signaling - 2014

Antibacterial activity of pepducins, allosterical modulators of formyl Peptide receptor signaling.

Malene Winther, Michael Gabl, Tudor I Oprea, Bodil Jönsson, Francois Boulay, Johan Bylund, Claes Dahlgren, Huamei Forsman
Antimicrobial agents and chemotherapy - 2014

A Pepducin Derived from the Third Intracellular Loop of FPR2 Is a Partial Agonist for Direct Activation of This Receptor in Neutrophils But a Full Agonist for Cross-Talk Triggered Reactivation of FPR2

Michael Gabl, Malene Winther, Sarah Line Skovbakke, Johan Bylund, Claes Dahlgren, Huamei Forsman
Plos One - 2014

A novel receptor cross-talk between the ATP receptor P2Y2 and formyl peptide receptors reactivates desensitized neutrophils to produce superoxide.

Karin Önnheim, Karin Christenson, Michael Gabl, Joachim C Burbiel, Christa E Müller, Tudor I Oprea, Johan Bylund, Claes Dahlgren, Huamei Forsman
Experimental cell research - 2014

Measurement of respiratory burst products, released or retained, during activation of professional phagocytes.

Johan Bylund, Halla Björnsdottir, Martina Sundqvist, Anna Karlsson, Claes Dahlgren
Methods in molecular biology (Clifton, N.J.) - 2014

The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.

Huamei Forsman, Johan Bylund, Tudor I Oprea, Anna Karlsson, Francois Boulay, Marie-Josephe Rabiet, Claes Dahlgren
Biochimica et biophysica acta - 2013

Further studies on 2-arylacetamide pyridazin-3(2H)-ones: Design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.

Maria Paola Giovannoni, Igor A Schepetkin, Agostino Cilibrizzi, Letizia Crocetti, Andrei I Khlebnikov, Claes Dahlgren, Alessia Graziano, Vittorio Dal Piaz, Liliya N Kirpotina, Serena Zerbinati, Claudia Vergelli, Mark T Quinn
European journal of medicinal chemistry - 2013

The Human Neutrophil Subsets Defined by the Presence or Absence of OLFM4 Both Transmigrate into Tissue In Vivo and Give Rise to Distinct NETs In Vitro.

Amanda Welin, Firoozeh Amirbeagi, Karin Christenson, Lena Björkman, Halla Björnsdottir, Huamei Forsman, Claes Dahlgren, Anna Karlsson, Johan Bylund
PloS one - 2013

Reactivation of Desensitized Formyl Peptide Receptors by Platelet Activating Factor: A Novel Receptor Cross Talk Mechanism Regulating Neutrophil Superoxide Anion Production

Huamei Forsman, Karin Önnheim, Emil Andréasson, Karin Christenson, Anna Karlsson, Johan Bylund, Claes Dahlgren
Plos One - 2013

A non-peptide receptor inhibitor with selectivity for one of the neutrophil formyl peptide receptors, FPR 1.

Hülya Çevik Aras, Christina Kalderén, Annika Jenmalm Jensen, Tudor I Oprea, Claes Dahlgren, Huamei Forsman
Biochemical pharmacology - 2012

Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1.

Igor A Schepetkin, Andrei I Khlebnikov, Liliya N Kirpotina, Lars Brive, Mark A Jutila, Claes Dahlgren, Mark T Quinn
Journal of molecular modeling - 2012

Receptor-Dependent and -Independent Immunomodulatory Effects of Phenol-Soluble Modulin Peptides from Staphylococcus aureus on Human Neutrophils Are Abrogated through Peptide Inactivation by Reactive Oxygen Species

Huamei Forsman, Karin Christenson, Johan Bylund, Claes Dahlgren
Infection and Immunity - 2012

Structural Characterization and Inhibitory Profile of Formyl Peptide Receptor 2 Selective Peptides Descending from a PIP2-Binding Domain of Gelsolin.

Huamei Forsman, Emil Andréasson, Jennie Karlsson, Francois Boulay, Marie-Josèphe Rabiet, Claes Dahlgren
Journal of immunology (Baltimore, Md. : 1950) - 2012

WHAT FORMYL PEPTIDE RECEPTORS, IF ANY, ARE TRIGGERED BY COMPOUND 43 AND LIPOXIN A(4) ?

Huamei Forsman, Karin Önnheim, Emil Andreasson, Claes Dahlgren
Scandinavian journal of immunology - 2011

In vivo-transmigrated human neutrophils are resistant to antiapoptotic stimulation.

Karin Christenson, Lena Björkman, Jennie Karlsson, Martina Sundqvist, Charlotta Movitz, David P Speert, Claes Dahlgren, Johan Bylund
Journal of leukocyte biology - 2011

Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library.

Huamei Forsman, Christina Kalderén, Anna Nordin, Erik Nordling, Annika Jernmalm Jensen, Claes Dahlgren
Biochemical pharmacology - 2011

N-formyl peptide receptor 3 (FPR3) departs from the homologous FPR2/ALX with regard to the major processes governing chemoattractant receptor regulation, expression at the cell surface and phosphorylation.

Marie Josephe Rabiet, Laurence Macari, Claes Dahlgren, François Boulay
The Journal of biological chemistry - 2011

Host defense peptide LL-37 selectively reduces proinflammatory macrophage responses.

Kelly Brown, Grace F T Poon, Darlene Birkenhead, Olga M Pena, Reza Falsafi, Claes Dahlgren, Anna Karlsson, Johan Bylund, Robert E W Hancock, Pauline Johnson
Journal of immunology (Baltimore, Md. : 1950) - 2011

The anionic amphiphile SDS is an antagonist for the human neutrophil formyl peptide receptor 1.

Fredrik Bergh Thorén, Jennie Karlsson, Claes Dahlgren, Huamei Forsman
Biochemical pharmacology - 2010

A methodological approach to studies of desensitization of the formyl peptide receptor: Role of the read out system, reactive oxygen species and the specific agonist used to trigger neutrophils.

Jennie Karlsson, Johan Bylund, Charlotta Movitz, Lena Björkman, Huamei Forsman, Claes Dahlgren
Journal of immunological methods - 2010

The annexin I sequence gln(9)-ala(10)-trp(11)-phe(12) is a core structure for interaction with the formyl peptide receptor 1.

Charlotta Movitz, Lars Brive, Kristoffer Hellstrand, Marie-Josèphe Rabiet, Claes Dahlgren
The Journal of biological chemistry - 2010

The FPR2-induced rise in cytosolic calcium in human neutrophils relies on an emptying of intracellular calcium stores and is inhibited by a gelsolin-derived PIP2-binding peptide.

Huamei Forsman, Claes Dahlgren
BMC cell biology - 2010

Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

Johan Bylund, Kelly Brown, Charlotta Movitz, Claes Dahlgren, Anna Karlsson
Free radical biology & medicine - 2010

The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation.

Lena Björkman, John G Raynes, Chandrabala Shah, Anna Karlsson, Claes Dahlgren, Johan Bylund
Arthritis and rheumatism - 2010

The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes.

Åse Björstad, Galia Askarieh, Kelly Brown, Karin Christenson, Huamei Forsman, Karin Önnheim, Hsin-Ni Li, Susann Teneberg, Olaf Maier, Dick Hoekstra, Claes Dahlgren, Donald J Davidson, Johan Bylund
Antimicrobial agents and chemotherapy - 2009

Interplay between signaling via the formyl peptide receptor (FPR) and chemokine receptor 3 (CCR3) in human eosinophils.

Lena Svensson, Elin Redvall, Marianne Johnsson, Anna-Lena Stenfeldt, Claes Dahlgren, Christine Wennerås
Journal of leukocyte biology - 2009

Lipoxin A(4) metabolites/analogues from two commercial sources have no effects on TNF-alpha-mediated priming or activation through the neutrophil formyl peptide receptors.

Huamei Forsman, Claes Dahlgren
Scandinavian journal of immunology - 2009

The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels.

Jennie Karlsson, Anna-Lena Stenfeldt, Marie-Josèphe Rabiet, Johan Bylund, Huamei Forsman, Claes Dahlgren
Cell calcium - 2009

Divergent Effects on Phagocytosis by Macrophage-Derived Oxygen Radicals

Kelly Brown, Karin Christenson, Anna Karlsson, Claes Dahlgren, Johan Bylund
J Innate Immun - 2009

International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.

Richard D Ye, François Boulay, Ji Ming Wang, Claes Dahlgren, Craig Gerard, Marc Parmentier, Charles N Serhan, Philip M Murphy
Pharmacological reviews - 2009

The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist

Huamei Forsman, E. Salomonsson, Karin Önnheim, Jennie Karlsson, Åse Björstad, H. Leffler, Johan Bylund, Anna Karlsson, Claes Dahlgren
Glycobiology - 2008

Pneumolysin released during Streptococcus pneumoniae autolysis is a potent activator of intracellular oxygen radical production in neutrophils

Anna Martner, Claes Dahlgren, J. C. Paton, Agnes E Wold
Infection and Immunity - 2008

Tumour necrosis factor (TNF)-alpha primes murine neutrophils when triggered via formyl peptide receptor-related sequence 2, the murine orthologue of human formyl peptide receptor-like 1, through a process involving the type I TNF receptor and subcellular granule mobilization

Karin Önnheim, Johan Bylund, F. Boulay, Claes Dahlgren, Huamei Forsman
Immunology - 2008

Changes in the ratio between FPR and FPRL1 triggered superoxide production in human neutrophils-a tool in analysing receptor specific events

Huamei Fu, Jennie Karlsson, Lena Björkman, Anna-Lena Stenfeldt, Anna Karlsson, Johan Bylund, Claes Dahlgren
Journal of Immunological Methods - 2008

Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1

Lena Björkman, Jennie Karlsson, Anna Karlsson, M. J. Rabiet, F. Boulay, Huamei Fu, Johan Bylund, Claes Dahlgren
Journal of Leukocyte Biology - 2008

Antimicrobial host defence peptides of human neutrophils – roles in innate immunity

Åse Björstad, Kelly Brown, Huamei Fu, Claes Dahlgren, Anna Karlsson, Johan Bylund
Anti-Infective Agents in Medicinal Chemistry - 2008

Phagocyte-derived reactive oxygen species as suppressors of inflammatory disease

Lena Björkman, Claes Dahlgren, Anna Karlsson, Kelly Brown, Johan Bylund
Arthritis & Rheumatism - 2008

A new chemiluminescence paradox: selective inhibition of isoluminol-amplified activity in phagocytes by peptides from annexin AI.

Maria Dahlberg, Claes Dahlgren, Kristoffer Hellstrand, Charlotta Movitz
Luminescence : the journal of biological and chemical luminescence - 2008

Measurement of respiratory burst products generated by professional phagocytes

Claes Dahlgren, Anna Karlsson, Johan Bylund
Neutrophil Methods and Protocols. Mark T. QuinnFrank R. DeLeoGary M. Bokoch (red.) - 2007

Oxygen radical production and severity of the Guillain--Barré syndrome.

Natalia Mossberg, Oluf Andersen, Staffan Nilsson, Claes Dahlgren, Kristoffer Hellstrand, Magnus Lindh, Åke Svedhem, Tomas Bergström, Charlotta Movitz
Journal of neuroimmunology - 2007

The non-steroidal anti-inflammatory drug piroxicam blocks ligand binding to the formyl peptide receptor but not the formyl peptide receptor like 1

Anna-Lena Stenfeldt, Jennie Karlsson, Christine Wennerås, Johan Bylund, Huamei Fu, Claes Dahlgren
Biochem Pharmacol - 2007

House dust mite allergen activates human eosinophils via formyl peptide receptor and formyl peptide receptor-like 1

Lena Svensson, E. Redvall, C. Bjorn, Jenny Karlsson, A. M. Bergin, M. J. Rabiet, Claes Dahlgren, Christine Wennerås
Eur J Immunol - 2007

Cyclosporin H, Boc-MLF and Boc-FLFLF are Antagonists that Preferentially Inhibit Activity Triggered Through the Formyl Peptide Receptor

Anna-Lena Stenfeldt, Jennie Karlsson, Christine Wennerås, Johan Bylund, Huamei Fu, Claes Dahlgren
Inflammation - 2007

Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells

Anna Karlsson, Erik Nygren, Jenny Karlsson, Inger Nordström, Claes Dahlgren, Kristina Eriksson
Clin Vaccine Immunol - 2007

An attempt to design an isoluminol-hydrogen peroxidase-amplified CL that measures intracellularly produced H(2)O(2) in phagocytes: sensitivity for H(2)O(2) is not high enough to allow detection

Anna-Lena Stenfeldt, Claes Dahlgren
Luminescence - 2007

A Monocyte-Specific Peptide from Herpes Simplex Virus Type 2 Glycoprotein G Activates the NADPH-Oxidase but Not Chemotaxis through a G-Protein-Coupled Receptor Distinct from the Members of the Formyl Peptide Receptor Family.

Lars Bellner, Jennie Karlsson, Huamei Fu, François Boulay, Claes Dahlgren, Kristina Eriksson, Anna Karlsson
Journal of immunology (Baltimore, Md. : 1950) - 2007

Modifications of cellular responses to lysophosphatidic acid and platelet-activating factor by plasma gelsolin

Teresia Magnuson Osborn, Claes Dahlgren, J. H. Hartwig, T. P. Stossel
Am J Physiol Cell Physiol - 2007

The two neutrophil plasma membrane markers alkaline phosphatase and HLA class I antigen localize differently in granule-deficient cytoplasts. An ideal plasma membrane marker in human neutrophils is still lacking

Sara Pellmé, Claes Dahlgren, Anna Karlsson
J Immunol Methods - 2007

A skin chamber technique as a human model for studies of aseptic inflammatory reactions

P. Follin, Claes Dahlgren
Methods Mol Biol - 2007

Lipid raft proteome of the human neutrophil azurophil granule

Elisabeth Feuk-Lagerstedt, Charlotta Movitz, Sara Pellmé, Claes Dahlgren, Anna Karlsson
Proteomics - 2007

Localization of human neutrophil interleukin-8 (CXCL-8) to organelle(s) distinct from the classical granules and secretory vesicles

Sara Pellmé, M. Morgelin, H. Tapper, Ulf-Henrik Mellqvist, Claes Dahlgren, Anna Karlsson
J Leukoc Biol - 2006

Ligand recognition and activation of formyl peptide receptors in neutrophils

Huamei Fu, Jenny Karlsson, Johan Bylund, Charlotta Movitz, Anna Karlsson, Claes Dahlgren
J Leukoc Biol - 2006

Changes in activation states of murine polymorphonuclear leukocytes (PMN) during inflammation: a comparison of bone marrow and peritoneal exudate PMN

T. Itou, Vincent Collins, Fredrik Bergh Thorén, Claes Dahlgren, Anna Karlsson
Clinical and vaccine immunology - 2006

Neutrophil Secretion Induced by an Intracellular Ca(2+) Rise and Followed by Whole-Cell Patch-Clamp Recordings Occurs Without any Selective Mobilization of Different Granule Populations

Daniel Granfeldt, Olle Harbecke, Åse Björstad, Anna Karlsson, Claes Dahlgren
Journal of biomedicine & biotechnology - 2006

The peptide Trp-Lys-Tyr-Met-Val-D-Met activates neutrophils through the formyl peptide receptor only when signaling through the formylpeptide receptor like 1 is blocked. A receptor switch with implications for signal transduction studies with inhibitors and receptor antagonists

Jennie Karlsson, Huamei Fu, F. Boulay, Johan Bylund, Claes Dahlgren
Biochemical pharmacology - 2006

Human macrophages limit oxidation products in low density lipoprotein

Lillemor Mattsson Hultén, Christina Ullström, Alexandra Krettek, D. van Reyk, S. L. Marklund, Claes Dahlgren, Olov Wiklund
Lipids Health Dis - 2005

Neutrophil NADPH-oxidase activation by an annexin AI peptide is transduced by the formyl peptide receptor (FPR), whereas an inhibitory signal is generated independently of the FPR family receptors

Jennie Karlsson, Huamei Fu, F. Boulay, Claes Dahlgren, Kristoffer Hellstrand, Charlotta Movitz
Journal of leukocyte biology - 2005

Interleukin-8-derived peptide has antibacterial activity

Åse Björstad, Huamei Fu, Anna Karlsson, Claes Dahlgren, Johan Bylund
Antimicrobial agents and chemotherapy - 2005

Oxygen radical-induced natural killer cell dysfunction: role of myeloperoxidase and regulation by serotonin

Åsa Betten, Claes Dahlgren, Ulf-Henrik Mellqvist, Svante Hermodsson, Kristoffer Hellstrand
J Leukoc Biol - 2004

Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils

Johan Bylund, Sara Pellmé, Huamei Fu, Ulf-Henrik Mellqvist, Kristoffer Hellstrand, Anna Karlsson, Claes Dahlgren
BMC cell biology - 2004

A hepatitis C virus-encoded, nonstructural protein (NS3) triggers dysfunction and apoptosis in lymphocytes: role of NADPH oxidase-derived oxygen radicals

Fredrik Bergh Thorén, Ana Romero, Magnus Lindh, Claes Dahlgren, Kristoffer Hellstrand
Journal of leukocyte biology - 2004

A bactericidal cecropin-A peptide with a stabilized alpha-helical structure possess an increased killing capacity but no proinflammatory activity

Huamei Fu, Åse Björstad, Claes Dahlgren, Johan Bylund
Inflammation - 2004

Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe

Jenny Almkvist, Claes Dahlgren, H. Leffler, Anna Karlsson
Experimental cell research - 2004

The two neutrophil members of the formylpeptide receptor family activate the NADPH-oxidase through signals that differ in sensitivity to a gelsolin derived phosphoinositide-binding peptide

Huamei Fu, Lena Björkman, P. Janmey, Anna Karlsson, Jennie Karlsson, Charlotta Movitz, Claes Dahlgren
BMC cell biology - 2004

The mechanism for activation of the neutrophil NADPH-oxidase by the peptides formyl-Met-Leu-Phe and Trp-Lys-Tyr-Met-Val-Met differs from that for interleukin-8

Huamei Fu, Johan Bylund, Anna Karlsson, Sara Pellmé, Claes Dahlgren
Immunology - 2004

Histamine inhibits neutrophil NADPH oxidase activity triggered by the lipoxin A4 receptor-specific peptide agonist Trp-Lys-Tyr-Met-Val-Met

Åsa Betten, Claes Dahlgren, Svante Hermodsson, Kristoffer Hellstrand
Scand J Immunol - 2003

Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy

Huamei Fu, Claes Dahlgren, Johan Bylund
Antimicrob Agents Chemother - 2003

Outer membrane protein A deficient Escherichia coli activates neutrophils to produce superoxide and shows increased susceptibility to antibacterial peptides

Huamei Fu, A. A. Belaaouaj, Claes Dahlgren, Johan Bylund
Microbes Infect - 2003

Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium

Johan Bylund, Åse Björstad, Daniel Granfeldt, Anna Karlsson, Charlotte Woschnagg, Claes Dahlgren
J Biol Chem - 2003

Assembly and activation of the neutrophil NADPH oxidase in granule membranes.

Anna Karlsson, Claes Dahlgren
Antioxidants & redox signaling - 2002

Ionomycin-induced neutrophil NADPH oxidase activity is selectively inhibited by the serine protease inhibitor diisopropyl fluorophosphate.

Claes Dahlgren, Anna Karlsson
Antioxidants & redox signaling - 2002

Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1.

Jenny Almkvist, Claes Dahlgren, Anna Karlsson
Journal of immunology (Baltimore, Md. : 1950) - 2002

Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.

T Christophe, Anna Karlsson, M-J Rabiet, F Boulay, Claes Dahlgren
Scandinavian journal of immunology - 2002

Problems in identifying microbial-derived neutrophil activators, focusing on Helicobacter pylori

Johan Bylund, Claes Dahlgren
Trends Microbiol - 2002

Lipopolysaccharide-induced granule mobilization and priming of the neutrophil response to Helicobacter pylori peptide Hp(2-20), which activates formyl peptide receptor-like 1

Johan Bylund, Anna Karlsson, F. Boulay, Claes Dahlgren
Infect Immun - 2002

Neutrophil secretory vesicles are the intracellular reservoir for GPI-80, a protein with adhesion-regulating potential.

Claes Dahlgren, Anna Karlsson, F Sendo
Journal of leukocyte biology - 2001

Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe.

Jenny Almkvist, Jenny Fäldt, Claes Dahlgren, H Leffler, Anna Karlsson
Infection and immunity - 2001

The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2.

T Christophe, Anna Karlsson, C Dugave, M J Rabiet, F Boulay, Claes Dahlgren
The Journal of biological chemistry - 2001

Priming of human neutrophils by mycobacterial lipoarabinomannans: role of granule mobilisation.

Jenny Fäldt, Claes Dahlgren, Malin Ridell, Anna Karlsson
Microbes and infection - 2001

Different glycosphingolipid composition in human neutrophil subcellular compartments.

Anna Karlsson, Halina Miller-Podraza, P Johansson, Karl-Anders Karlsson, Claes Dahlgren, Susann Teneberg
Glycoconjugate journal - 2001

Proinflammatory activity of a cecropin-like antibacterial peptide from Helicobacter pylori

Johan Bylund, T. Christophe, F. Boulay, Thomas Nyström, Anna Karlsson, Claes Dahlgren
Antimicrob Agents Chemother - 2001

A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis

Åsa Betten, Johan Bylund, T. Christophe, F. Boulay, Ana Romero, Kristoffer Hellstrand, Claes Dahlgren
J Clin Invest - 2001

The synthetic chemoattractant Trp-Lys-Tyr-Met-Val-DMet activates neutrophils preferentially through the lipoxin A(4) receptor.

Claes Dahlgren, T Christophe, F Boulay, Phoebus Madianos, M J Rabiet, Anna Karlsson
Blood - 2000

Alleviating oxidative stress in cancer immunotherapy: a role for histamine?

Kristoffer Hellstrand, Mats Brune, Claes Dahlgren, Markus Hansson, Svante Hermodsson, Per Lindnér, Ulf-Henrik Mellqvist, Peter Naredi
Medical oncology (Northwood, London, England) - 2000

Endogenous cleavage of annexin I generates a truncated protein with a reduced calcium requirement for binding to neutrophil secretory vesicles and plasma membrane

Charlotta Movitz, Claes Dahlgren
Biochim Biophys Acta - 2000

The phagocyte chemiluminescence paradox: luminol can act as an inhibitor of neutrophil NADPH-oxidase activity.

Jenny Fäldt, Malin Ridell, Anna Karlsson, Claes Dahlgren
Luminescence : the journal of biological and chemical luminescence - 1999

Respiratory burst in human neutrophils.

Claes Dahlgren, Anna Karlsson
Journal of immunological methods - 1999

Activation of human neutrophils by mycobacterial phenolic glycolipids.

Jenny Fäldt, Claes Dahlgren, Anna Karlsson, A M Ahmed, D E Minnikin, Malin Ridell
Clinical and experimental immunology - 1999

Identification of CD66a and CD66b as the major galectin-3 receptor candidates in human neutrophils.

Elisabeth Feuk-Lagerstedt, E T Jordan, H Leffler, Claes Dahlgren, Anna Karlsson
Journal of immunology (Baltimore, Md. : 1950) - 1999

Cultured rat and purified human Pneumocystis carinii stimulate intra- but not extracellular free radical production in human neutrophils.

T Jensen, E M Aliouat, B Lundgren, O P Settnes, Anna Karlsson, Claes Dahlgren, E Dei-Cas, N Obel
The Journal of eukaryotic microbiology - 1998

Desensitization of formyl peptide receptors is abolished in calcium ionophore-primed neutrophils: an association of the ligand-receptor complex to the cytoskeleton is not required for a rapid termination of the NADPH-oxidase response.

Olle Harbecke, Hans-Björne Elwing, P Follin, Anna Karlsson, Claes Dahlgren
Journal of immunology (Baltimore, Md. : 1950) - 1998

Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils.

Anna Karlsson, P Follin, H Leffler, Claes Dahlgren
Blood - 1998

L Liu, Hans-Björne Elwing, Anna Karlsson, Claes Dahlgren
Clinical and experimental immunology - 1997

Secretion of type-1-fimbriae binding proteins from human neutrophil granulocytes.

Anna Karlsson, Claes Dahlgren
Inflammation - 1996

Identification of the lysosomal membrane glycoprotein Lamp-1 as a receptor for type-1-fimbriated (mannose-specific) Escherichia coli.

Anna Karlsson, S R Carlsson, Claes Dahlgren
Biochemical and biophysical research communications - 1996

Lack of correlation between NADPH-oxidase priming and elevated alkaline phosphatase activity in cord blood neutrophils.

L Khalfan, Anna Karlsson, H Lundqvist, B Björkstén, Claes Dahlgren
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1995

Different subcellular localization of cytochrome b and the dormant NADPH-oxidase in neutrophils and macrophages: effect on the production of reactive oxygen species during phagocytosis.

A Johansson, A J Jesaitis, H Lundqvist, K E Magnusson, C Sjölin, Anna Karlsson, Claes Dahlgren
Cellular immunology - 1995

The lysosomal membrane glycoproteins Lamp-1 and Lamp-2 are present in mobilizable organelles, but are absent from the azurophil granules of human neutrophils.

Claes Dahlgren, S R Carlsson, Anna Karlsson, H Lundqvist
The Biochemical journal - 1995

Escherichia coli-induced activation of neutrophil NADPH-oxidase: lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites.

Anna Karlsson, M Markfjäll, Niklas Strömberg, Claes Dahlgren
Infection and immunity - 1995

Neutrophil alkaline phosphatase activity increase in bacterial infections is not associated with a general increase in secretory vesicle membrane components.

Anna Karlsson, L Khalfan, Claes Dahlgren, T Stigbrand, P Follin
Infection and immunity - 1995

Detection of glycoprotein receptors on blotting membranes by binding of live bacteria and amplification by growth.

Anna Karlsson, Niklas Strömberg, Claes Dahlgren
Analytical biochemistry - 1995

Phagocytosis following translocation of the neutrophil b-cytochrome from the specific granule to the plasma membrane is associated with an increased leakage of reactive oxygen species.

H Lundqvist, Anna Karlsson, P Follin, C Sjölin, Claes Dahlgren
Scandinavian journal of immunology - 1992

Claes Dahlgren

Professor emeritus

Publikationer