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- Barbro Linderholm
Barbro Linderholm
Adjunct Senior Lecturer
Department of Oncology-
Risk Factors for Developing Brain Metastasis for Patients with HER2-Positive Breast
Cancer
Leif Klint, Aniko Kovács, Barbro Linderholm
Annals of Medical and Clinical Oncology - 2024 -
Metronomic chemotherapy using capecitabine and cyclophosphamide in metastatic breast cancer - efficacy, tolerability and quality of life results from the phase II METRO
trial
Karolina Larsson, Jamila Adra, Leif Klint, Barbro Linderholm
BREAST - 2024 -
Tumor-Infiltrating Lymphocytes in Triple-Negative Breast
Cancer
Roberto A. Leon-Ferre, Sarah Flora Jonas, Roberto Salgado, Sherene Loi, Vincent de Jong, Jodi M. Carter, Torsten O. Nielsen, Samuel Leung, Nazia Riaz, Stephen Chia, Gerome Jules-Clement, Giuseppe Curigliano, Carmen Criscitiello, Vincent Cockenpot, Matteo Lambertini, Vera J. Suman, Barbro Linderholm, John W. M. Martens, Carolien H. M. van Deurzen, A. Mieke Timmermans, Tatsunori Shimoi, Shu Yazaki, Masayuki Yoshida, Sung-Bae Kim, Hee Jin Lee, Maria Vittoria Dieci, Guillaume Bataillon, Anne Vincent-Salomon, Fabrice Andre, Marleen Kok, Sabine C. Linn, Matthew P. Goetz, Stefan Michiels
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION - 2024 -
Cost-Effectiveness Analysis of Adjuvant Olaparib Versus Watch and Wait in the Treatment of Germline BRCA1/2-Mutated, High-Risk, HER2-Negative Early Breast Cancer in
Sweden
Maria Polyzoi, Mattias Ekman, Anja Reithmeier, Johanna Jacob, Emma Karlsson, Evelina Bertranou, Barbro Linderholm, Robert Hettle
PHARMACOECONOMICS-OPEN - 2024 -
Compliance to adjuvant endocrine therapy and survival in breast cancer
patients
Chaido Chamalidou, Salmir Nasic, Barbro Linderholm
Cancer Treatment and Research Communications - 2023 -
Impact of BMI in Patients With Early Hormone Receptor-Positive Breast Cancer Receiving Endocrine Therapy With or Without Palbociclib in the PALLAS
Trial
Georg Pfeiler, Dominik Hlauschek, Erica L. Mayer, Christine Deutschmann, Stephanie Kacerovsky-Strobl, Miguel Martin, Jane Lowe Meisel, Nicholas Zdenkowski, Sibylle Loibl, Marija Balic, Haeseong Park, Aleix Prat, Claudine Isaacs, Emilio Bajetta, Justin M. Balko, Merixtell Bellet-Ezquerra, Judith Bliss, Harold Burstein, Fatima Cardoso, Hannes Fohler, Theodoros Foukakis, Karen A. Gelmon, Matthew Goetz, Tufia C. Haddad, Hiroji Iwata, Jacek Jassem, Soo-Chin Lee, Barbro Linderholm, Maartje Los, Eleftherios P. Mamounas, Kathy D. Miller, Patrick G. Morris, Elisabetta Munzone, Einav Nili Gal-Yam, Alistair Ring, Lois Shepherd, Christian Singer, Christoph Thomssen, Ling-Ming Tseng, Pinuccia Valagussa, Eric P. Winer, Antonio C. Wolff, Gabriele Zoppoli, Jana Machacek-Link, Celine Schurmans, Xin Huang, Eric Gauthier, Christian Fesl, Amylou C. Dueck, Angela DeMichele, Michael Gnant
JOURNAL OF CLINICAL ONCOLOGY - 2023 -
De Novo Oligometastatic Breast
Cancer
Lajos Pusztai, Mariya Rozenblit, Peter Dubsky, Thomas Bachelot, Anna M. Kirby, Barbro Linderholm, Julia R. White, Steven J. Chmura, Lisa A. Carey, Boon H. Chua, Kathy D. Miller
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 2023 -
Designing clinical trials based on modern imaging and metastasis-directed treatments in patients with oligometastatic breast cancer: a consensus recommendation from the EORTC Imaging and Breast Cancer
Groups
David Pasquier, Luc Bidaut, Daniela Elena Oprea-Lager, Nandita M. deSouza, David Krug, Laurence Collette, Wolfgang Kunz, Yazid Belkacemi, Maria Grazia Bau, Caroline Caramella, Lioe Fee De Geus-Oei, Alex De Caluwé, Christophe Deroose, Olivier Gheysens, Ken Herrmann, Isabelle Kindts, Michalis Kontos, Sherko Kümmel, Barbro Linderholm, Egesta Lopci, Icro Meattini, Ann Smeets, Orit Kaidar-Person, Philip Poortmans, Pelagia Tsoutsou, Nawale Hajjaji, Nicola Russell, Elżbieta Senkus, Jean Noël Talbot, Lale Umutlu, Vincent Vandecaveye, Joost J.C. Verhoeff, Willemien Menke van der Houven van Oordt, Helle D. Zacho, Fatima Cardoso, Laure Fournier, Frederieke Van Duijnhoven, Frédéric E. Lecouvet
The Lancet Oncology - 2023 -
Overall survival in the OlympiA phase Ill trial of adjuvant olaparib in patients with germime pathogenic variants in BRCA1/2 and high-risk, early breast
cancer
C. E. Geyer, J. E. Garber, R. D. Gelber, G. Yothers, M. Taboada, L. Ross, P. Rastogi, K. Cui, A. Arahmani, G. Aktan, A. C. Armstrong, M. Arnedos, J. Balmana, J. Bergh, J. Bliss, S. Delaloge, S. M. Domchek, A. Eisen, F. Elsafy, L. E. Fein, A. Fielding, J. M. Ford, S. Friedman, K. A. Gelmon, L. Gianni, M. Gnant, S. J. Hollingsworth, S. A. Im, A. Jager, S. R. Lakhani, W. Janni, Barbro Linderholm, T. W. Liu, N. Loman, L. Korde, S. Loibl, P. C. Lucas, F. Marme, E. M. de Duenas, R. McConnell, K. A. Phillips, M. Piccart, G. Rossi, R. Schmutzler, E. Senkus, Z. Shao, P. Sharma, C. F. Singer, T. Spanic, E. Stickeler, M. Toi, T. A. Traina, G. Viale, G. Zoppoli, Y. H. Park, R. Yerushalmi, H. Yang, D. Pang, K. H. Jung, A. Mailliez, Z. Fan, I. Tennevet, J. Zhang, T. Nagy, G. S. Sonke, Q. Sun, M. Parton, M. A. Colleoni, M. Schmidt, A. M. Brufsky, W. Razaq, B. Kaufman, D. Cameron, C. Campbell, A. N. J. Tutt, O. T. Johannsson
Annals of Oncology - 2022 -
Real world data on adjuvant treatment of older HER2-positive breast cancer patients – A single institution experience through 8
years
Leif Klint, A. Kovács, Elisabeth Werner Rönnerman, Barbro Linderholm
Cancer Treatment and Research Communications - 2021 -
Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary
tumors.
Anna Thulin, Carola Andersson, Elisabeth Werner Rönnerman, Shahin De Lara, Chaido Chamalidou, Arnd Schoenfeld, Anikó Kovács, Henrik Fagman, Fredrik Enlund, Barbro Linderholm
Scientific reports - 2021 -
Delta NT-proBNP predicts cardiotoxicity in HER2-positive breast cancer patients treated with
trastuzumab.
Anton E Andersson, Barbro Linderholm, Daniel Giglio
Acta oncologica (Stockholm, Sweden) - 2021 -
Adjuvant Olaparib for Patients with BRCA1- or BRCA2-Mutated Breast
Cancer
A. N. J. Tutt, J. E. Garber, B. Kaufman, G. Viale, D. Fumagalli, P. Rastogi, R. D. Gelber, E. de Azambuja, A. Fielding, J. Balmana, S. M. Domchek, K. A. Gelmon, S. J. Hollingsworth, L. A. Korde, Barbro Linderholm, H. Bandos, E. Senkus, J. M. Suga, Z. Shao, A. W. Pippas, Z. Nowecki, T. Huzarski, P. A. Ganz, P. C. Lucas, N. Baker, S. Loibl, R. McConnell, M. Piccart, R. Schmutzler, G. G. Steger, J. P. Costantino, A. Arahmani, N. Wolmark, E. McFadden, V. Karantza, S. R. Lakhani, G. Yothers, C. Campbell, C. E. Geyer, A. Clinical Trial Steering Olympi
New England Journal of Medicine - 2021 -
Breaking Bad News in Cancer Care: Ethiopian Patients Want More Information Than What Family and the Public Want Them to
Have.
Aynalem Abraha Woldemariam, Rune Andersson, Christian Munthe, Barbro Linderholm, Nataliya Berbyuk Lindström
JCO global oncology - 2021 -
Evaluation of multiple transcriptomic gene risk signatures in male breast
cancer.
Jane Bayani, Coralie Poncet, Cheryl Crozier, Anouk Neven, Tammy Piper, Carrie Cunningham, Monika Sobol, Stefan Aebi, Kim Benstead, Oliver Bogler, Lissandra Dal Lago, Judith Fraser, Florentine Hilbers, Ingrid Hedenfalk, Larissa Korde, Barbro Linderholm, John Martens, Lavinia Middleton, Melissa Murray, Catherine Kelly, Cecilia Nilsson, Monika Nowaczyk, Stephanie Peeters, Aleksandra Peric, Peggy Porter, Carolien Schröder, Isabel T Rubio, Kathryn J Ruddy, Christi van Asperen, Danielle Van Den Weyngaert, Carolien van Deurzen, Elise van Leeuwen-Stok, Joanna Vermeij, Eric Winer, Sharon H Giordano, Fatima Cardoso, John M S Bartlett
NPJ breast cancer - 2021 -
Survival patterns of invasive lobular and invasive ductal breast cancer in a large population-based cohort with two decades of follow
up.
Chaido Chamalidou, H Fohlin, Per Albertsson, L-G Arnesson, Zakaria Einbeigi, Erik Holmberg, A Nordenskjöld, B Nordenskjöld, Per Karlsson, Barbro Linderholm
Breast (Edinburgh, Scotland) - 2021 -
Breaking bad news in cancer care: preferences of patients, family caregivers and general public in
Ethiopia
Aynalem Abraha, Rune Andersson, Christian Munthe, Barbro Linderholm, Nataliya Berbyuk Lindström
International Conference on Communication in Healthcare (ICCH) 2020 Part 2, 15-16 April, 2021 - 2021 -
Efficacy and tolerability of metronomic chemotherapy in patients with metastatic breast cancer - an international experience in West Sweden and in the South of
Ireland.
Catherine Weadick, Karolina Larsson, Seamus O'Reilly, Eileen McMahon, Deirdre O'Mahony, Barbro Linderholm
Cancer Treatment and Research Communications - 2020 -
Adjuvant chemotherapy and survival in women aged 70 years and older with triple-negative breast cancer: a Swedish population-based propensity score-matched
analysis
Slavica Janeva, Chenyang Zhang, Anikó Kovács, Toshima Z Parris, Jennifer A. Crozier, Christopher M. Pezzi, Barbro Linderholm, Riccardo A Audisio, Roger Olofsson Bagge
The Lancet Healthy Longevity - 2020 -
Person- and Family-Centeredness in Ethiopian Cancer Care: Improving Communication, Ethics, Decision Making and
Health
Nataliya Berbyuk Lindström, Aynalem Abraha, Abebe Bekele, Christian Munthe, Rune Andersson, Betlehem Girma Kebede, Barbro Linderholm, Tigeneh Wondemagegnehu
JMIR Research Protocols - 2020 -
Personalised medicine and the decision to withhold chemotherapy in early breast cancer with intermediate risk of recurrence - a systematic review and
meta-analysis.
Susanna Maria Wallerstedt, Astrid Nilsson Ek, Roger Olofsson Bagge, Anikó Kovács, Annika Strandell, Barbro Linderholm
European journal of clinical pharmacology - 2020 -
Communicative challenges among physicians, patients, and family caregivers in cancer care: An exploratory qualitative study in
Ethiopia
Betlehem Girma Kebede, Aynalem Abraha, Rune Andersson, Christian Munthe, Mats Linderholm, Barbro Linderholm, Nataliya Berbyuk Lindström
PLoS ONE - 2020 -
Clinical outcome of patients with brain metastases from breast cancer - A population based study over 21
years.
Anna Thulin, Elisabeth Werner Rönnerman, Chenyang Zhang, Shahin De Lara, Chaido Chamalidou, Arnd Schoenfeldt, Carola Andersson, Anikó Kovács, Fredrik Enlund, Barbro Linderholm
Breast - 2020 -
Compared expression of Tumour Infiltrating Lymphocytes and FOXA1 in matched pairs of brain metastasis and primary breast cancer and prognostic implications – a pilot
study
Anna Thulin, Elisabeth Werner Rönnerman, Shahin De Lara, C. Chamalidou, A. Schoenfeldt, Anikó Kovács, Barbro Linderholm
European Journal of Cancer. 138, suppl. 1, S63-S64 - 2020 -
A comparison between young and old patients with triple-negative breast cancer: biology, survival and metastatic
patterns
Anna-Karin Tzikas, Szilard Nemes, Barbro Linderholm
Breast Cancer Research and Treatment - 2020 -
Long-term safety and survival outcomes from the Scandinavian Breast Group 2004-1 randomized phase II trial of tailored dose-dense adjuvant chemotherapy for early breast
cancer.
Alexios Matikas, Sara Margolin, Mats Hellström, Hemming Johansson, Nils-Olof Bengtsson, Lena Karlsson, Per Edlund, Per Karlsson, Elisabet Lidbrink, Barbro Linderholm, Henrik Lindman, Per Malmstrom, Kenneth Villman, Theodoros Foukakis, Jonas Bergh
Breast cancer research and treatment - 2018 -
Spousal Cancer: A Systematic Review and Case Report of a Metachronous Presentation of Breast Cancer in a Genetically Unrelated
Couple
Anikó Kovács, Toshima Z Parris, Barbro Linderholm
Clinics in Oncology - 2017 -
The MAGIC survey in hormone receptor positive (HR+), HER2-negative (HER2−) breast cancer: When might multigene assays be of
value?
Matti Aapro, Michelino De Laurentiis, Dan Rea, Juan Enrique Bargallo Rocha, Roberto Elizalde, László Landherr, Barbro Linderholm, Eleftherios Mamounas, Christos Markopoulos, Patrick Neven, Alexander Petrovsky, Roman Rouzier, Vincent Smit, Christer Svedman, Daniel Schneider, Christoph Thomssen, Miguel Martin
Breast - 2017 -
Low-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial
22-00
M. Colleoni, K. P. Gray, S. Gelber, I. Lang, B. Thurlimann, L. Gianni, E. A. Abdi, H. L. Gomez, Barbro Linderholm, F. Puglisi, C. Tondini, E. Kralidis, A. Eniu, K. Cagossi, D. Rauch, J. Chirgwin, R. D. Gelber, M. M. Regan, A. S. Coates, K. N. Price, G. Viale, A. Goldhirsch
Journal of Clinical Oncology - 2016 -
Transcriptional profiling of breast cancer metastases identifies liver metastasis-selective genes associated with adverse outcome in luminal A primary breast
cancer.
Siker Kimbung, Ida Johansson, Anna Danielsson, Srinivas Veerla, Suzanne Egyhazi Brage, Marianne Frostvik Stolt, Lambert Skoog, Lena Carlsson, Zakaria Einbeigi, Elisabet Lidbrink, Barbro Linderholm, Niklas Loman, Per Malmström, Martin Söderberg, Thomas M Walz, Mårten Fernö, Thomas Hatschek, Ingrid A Hedenfalk
Clinical cancer research : an official journal of the American Association for Cancer Research - 2016 -
Proteomics profiling identify CAPS as a potential predictive marker of tamoxifen resistance in estrogen receptor positive breast
cancer.
Henrik J Johansson, Betzabe C Sanchez, Jenny Forshed, Olle Stål, Helena Fohlin, Rolf Lewensohn, Per Hall, Jonas Bergh, Janne Lehtiö, Barbro Linderholm
Clinical proteomics - 2015 -
Molecular subtype and tumor characteristics of breast cancer metastases as assessed by gene expression significantly influence patient post-relapse
survival.
N P Tobin, J C Harrell, J Lövrot, S Egyhazi Brage, M Frostvik Stolt, L Carlsson, Zakaria Einbeigi, Barbro Linderholm, N Loman, M Malmberg, T Walz, M Fernö, C M Perou, J Bergh, T Hatschek, L S Lindström
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO - 2015 -
Molecular profiling of male breast cancer - lost in
translation?
Ida Johansson, Fredrika Killander, Barbro Linderholm, Ingrid Hedenfalk
The international journal of biochemistry & cell biology - 2014 -
Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast
cancer.
Ning Qing Liu, Christoph Stingl, Maxime P Look, Marcel Smid, René B H Braakman, Tommaso De Marchi, Anieta M Sieuwerts, Paul N Span, Fred C G J Sweep, Barbro Linderholm, Anita Mangia, Angelo Paradiso, Luc Y Dirix, Steven J Van Laere, Theo M Luider, John W M Martens, John A Foekens, Arzu Umar
Journal of the National Cancer Institute - 2014 -
Angiogenic factors in relation to clinical effect in a phase II trial of weekly
paclitaxel.
Barbro Linderholm, E Lidbrink, E Tallroth, Zakaria Einbeigi, H Svensson, A von Wachenfeldt, B Norberg, L Carlsson, M E Olsson, J Bergh, N Wilking, T Hatschek
Breast (Edinburgh, Scotland) - 2013 -
Serum thymidine kinase activity compared with CA 15-3 in locally advanced and metastatic breast cancer within a randomized
trial.
J Bjöhle, J Bergqvist, J S Gronowitz, H. Johansson, L Carlsson, Zakaria Einbeigi, Barbro Linderholm, N Loman, M Malmberg, M Söderberg, M Sundquist, T M Walz, M Fernö, J Bergh, T Hatschek
Breast cancer research and treatment - 2013 -
Identification of intermediate risk breast cancer patients with1-3 positive lymph nodes and excellent survival after tamoxifen as only systemic adjuvant therapy by use of markers of proliferation and
apoptosis.
Barbro Linderholm, S Linder, L-G Arnesson, O Stål
Breast (Edinburgh, Scotland) - 2013 -
Retinoic acid receptor alpha is associated with tamoxifen resistance in breast
cancer.
Henrik J Johansson, Betzabe C Sanchez, Filip Mundt, Jenny Forshed, Anikó Kovács, Elena Panizza, Lina Hultin-Rosenberg, Bo Lundgren, Ulf Martens, Gyöngyvér Máthé, Zohar Yakhini, Khalil Helou, Kamilla Krawiec, Lena Kanter, Anders Hjerpe, Olle Stål, Barbro Linderholm, Janne Lehtiö
Nature communications - 2013 -
Impact of the first tumor response at eight weeks on overall survival in metastatic breast cancer patients treated with first-line combination
chemotherapy.
Chikako Suzuki, Lennart Blomqvist, Thomas Hatschek, Lena Carlsson, Zakaria Einbeigi, Barbro Linderholm, Birgitta Lindh, Niklas Loman, Martin Malmberg, Samuel Rotstein, Martin Söderberg, Marie Sundqvist, Thomas M Walz, Gunnar Aström, Hirofumi Fujii, Hans Jacobsson, Bengt Glimelius
Medical oncology (Northwood, London, England) - 2013 -
Triple negative breast cancer: Proposals for a pragmatic definition and implications for patient management and trial
design.
W Eiermann, J Bergh, F Cardoso, P Conte, J Crown, N J Curtin, J Gligorov, B Gusterson, H Joensuu, Barbro Linderholm, M Martin, F Penault-Llorca, B C Pestalozzi, E Razis, C Sotiriou, S Tjulandin, G Viale
Breast - 2012 -
Individually tailored treatment with epirubicin and paclitaxel with or without capecitabine as first-line chemotherapy in metastatic breast cancer: a randomized multicenter
trial.
T Hatschek, Lena M S Carlsson, Zakaria Einbeigi, E Lidbrink, Barbro Linderholm, B Lindh, N Loman, M Malmberg, S Rotstein, M Söderberg, Malin Sundquist, T M Walz, Mikael Hellström, Helene Svensson, Rolf-Göran Åström, Y Brandberg, J Carstensen, M Fernö, J Bergh
Breast cancer research and treatment - 2012 -
Diagnostic and prognostic role of plasma levels of two forms of cytokeratin 18 in patients with non-small-cell lung
cancer.
Luigi De Petris, Eva Brandén, Richard Herrmann, Betzabe Chavez Sanchez, Hirsh Koyi, Barbro Linderholm, Rolf Lewensohn, Stig Linder, Janne Lehtiö
European journal of cancer - 2011 -
Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised
trials.
S Darby, P McGale, C Correa, C Taylor, R Arriagada, M Clarke, D Cutter, C Davies, M Ewertz, J Godwin, R Gray, L Pierce, T Whelan, Y Wang, R Peto, Barbro Linderholm
Lancet - 2011 -
Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised
trials.
C Davies, J Godwin, R Gray, M Clarke, D Cutter, S Darby, P McGale, H C Pan, C Taylor, Y C Wang, M Dowsett, J Ingle, R Peto, Barbro Linderholm
Lancet - 2011 -
A randomised feasibility/phase II study (SBG 2004-1) with dose-dense/tailored epirubicin, cyclophoshamide (EC) followed by docetaxel (T) or fixed dosed dose-dense EC/T versus T, doxorubicin and C (TAC) in node-positive breast
cancer.
Sara Margolin, Nils-Olof Bengtsson, Lena Carlsson, Per Edlund, Mats Hellstrøm, Per Karlsson, Elisabet Lidbrink, Barbro Linderholm, Henrik Lindman, Per Malmström, Dagny Pettersson Skøld, Martin Søderberg, Kenneth Villman, Jonas Bergh
Acta oncologica (Stockholm, Sweden) - 2011 -
Vascular endothelial growth factor receptor 2 and downstream p38 mitogen-activated protein kinase are possible candidate markers of intrinsic resistance to adjuvant endocrine treatment in steroid receptor positive breast
cancer.
Barbro Linderholm, Henrik Hellborg, Ulla Johansson, Lambert Skoog, Janne Lehtiö
Breast cancer research and treatment - 2011 -
Prolonged tamoxifen treatment increases relapse-free survival for patients with primary breast cancer expressing high levels of
VEGF.
B C Sanchez, M Sundqvist, H Fohlin, F Spyratos, B Nordenskjöld, O Stål, Barbro Linderholm
European journal of cancer (Oxford, England : 1990) - 2010 -
Shorter survival-times following adjuvant endocrine therapy in oestrogen- and progesterone-receptor positive breast cancer overexpressing HER2 and/or with an increased expression of vascular endothelial growth
factor.
Barbro Linderholm, J Bergqvist, H Hellborg, U Johansson, M Linderholm, E von Schoultz, G Elmberger, L Skoog, J Bergh
Medical oncology (Northwood, London, England) - 2009 -
Improved survival for women with stage I breast cancer in south-east Sweden: a comparison between two time periods before and after increased use of adjuvant systemic
therapy.
Patrik Johansson, Helena Fohlin, Lars-Gunnar Arnesson, Monika Dufmats, Kerstin Nordenskjöld, Bo Nordenskjöld, Olle Stål, Barbro Linderholm
Acta oncologica (Stockholm, Sweden) - 2009 -
Significantly higher levels of vascular endothelial growth factor (VEGF) and shorter survival times for patients with primary operable triple-negative breast
cancer.
Barbro Linderholm, H Hellborg, U Johansson, G Elmberger, L Skoog, J Lehtiö, R Lewensohn
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO - 2009