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- Edward Trybala
Edward Trybala
Researcher
Department of Infectious Diseases-
Identification of epidermal growth factor receptor-tyrosine kinase inhibitor targeting the VP1 pocket of human
rhinovirus
Masum Miah, Andrew M. Davis, Charles Hannoun, Joanna Said, Martina Fitzek, Marian Preston, Dave Smith, Colores Uwamariya, Ambjörn Kärmander, Thomas Lundback, Tomas Bergström, Edward Trybala
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY - 2024 -
Crotofolane Diterpenoids and Other Constituents Isolated from Croton
kilwae.
Emanuel T Mahambo, Colores Uwamariya, Masum Miah, Leandro da Costa Clementino, Luis Carlos Salazar Alvarez, Gabriela Paula Di Santo Metzler, Edward Trybala, Joanna Said, Lianne H E Wieske, Jas S Ward, Kari Rissanen, Joan J E Munissi, Fabio T M Costa, Per Sunnerhagen, Tomas Bergström, Stephen S Nyandoro, Mate Erdelyi
Journal of Natural Products - 2023 -
Structure and Role of O-Linked Glycans in Viral Envelope
Proteins
Sigvard Olofsson, M. Bally, Edward Trybala, Tomas Bergström
Annual Review of Virology - 2023 -
Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2
Interaction
S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, M. Wand, Kristina Nyström, Joanna Said, Y. X. Setoh, A. A. Amarilla, N. Modhiran, J. D. J. Sng, M. Chhabra, P. R. Young, D. J. Rawle, M. A. Lima, E. A. Yates, R. Karlsson, R. L. Miller, Y. H. Chen, I. Bagdonaite, Z. Yang, J. Stewart, D. Nguyen, S. Laidlaw, E. Hammond, K. Dredge, T. M. A. Wilkinson, D. Watterson, A. A. Khromykh, A. Suhrbier, M. W. Carroll, Edward Trybala, Tomas Bergström, V. Ferro, M. A. Skidmore, J. E. Turnbull
ACS Central Science - 2022 -
Modified ent-Abietane Diterpenoids from the Leaves of Suregada
zanzibariensis
T. M. Kalenga, J. T. Mollel, Joanna Said, A. Orthaber, J. S. Ward, Y. Atilaw, D. Umereweneza, M. M. Ndoile, J. J. E. Munissi, K. Rissanen, Edward Trybala, Tomas Bergström, S. S. Nyandoro, M. Erdelyi
Journal of Natural Products - 2022 -
Cellular Chondroitin Sulfate and the Mucin-like Domain of Viral Glycoprotein C Promote Diffusion of Herpes Simplex Virus 1 While Heparan Sulfate Restricts
Mobility
Y. Abidine, L. F. Liu, O. Wallen, Edward Trybala, Sigvard Olofsson, Tomas Bergström, M. Bally
Viruses - 2022 -
Anti-respiratory syncytial virus and anti-herpes simplex virus activity of six Tanzanian medicinal plants with extended studies of Erythrina abyssinica stem
bark
Jackson T. Mollel, Joanna Said, R. J. Masalu, Charles Hannoun, M. V. N. Mbunde, R. S. O. Nondo, Tomas Bergström, Edward Trybala
Journal of Ethnopharmacology - 2022 -
Surveillance of wastewater revealed peaks of SARS-CoV-2 preceding those of hospitalized patients with
COVID-19
Fredy Saguti, Ellen Magnil, Lucica Enache, Marianela Patzi Churqui, Anette Johansson, Douglas Lumley, Fredrik Davidsson, Leif Dotevall, Ann Mattsson, Edward Trybala, Martin Lagging, Magnus Lindh, Magnus Gisslén, Thomas Brezicka, Kristina Nyström, Heléne Norder
Water Research - 2021 -
Antiviral iridoid glycosides from Clerodendrum
myricoides
D. Umereweneza, Jackson T. Molel, Joanna Said, Y. Atilaw, T. Muhizi, Edward Trybala, Tomas Bergström, A. Gogoll, M. Erdelyi
Fitoterapia - 2021 -
Herpes Simplex Virus Type 2 Mucin-Like Glycoprotein mgG Promotes Virus Release from the Surface of Infected
Cells
Edward Trybala, N. Peerboom, Beata Adamiak, Malgorzata Krzyzowska, Jan-Åke Liljeqvist, M. Bally, Tomas Bergström
Viruses - 2021 -
Herpes Simplex Virus 1 and 2 Infections during Differentiation of Human Cortical
Neurons
Petra Bergström, Edward Trybala, Charlotta Eriksson, Maria Johansson, Tugce Munise Satir, Sibylle Widehn, Stefanie Fruhwürth, W. Michno, Faisal Hayat Nazir, Jörg Hanrieder, Sören R Paludan, Lotta Agholme, Henrik Zetterberg, Tomas Bergström
Viruses-Basel - 2021 -
Surveillance of wastewater revealed peaks of SARS-CoV-2 preceding those of hospitalized patients with
COVID-19.
Fredy Saguti, Ellen Magnil, Lucica Enache, Marianela Patzi Churqui, Anette Johansson, Douglas Lumley, Fredrik Davidsson, Leif Dotevall, Ann Mattsson, Edward Trybala, Martin Lagging, Magnus Lindh, Magnus Gisslén, Thomas Brezicka, Kristina Nyström, Helene Norder
Water research - 2021 -
Cell Membrane Derived Platform To Study Virus Binding Kinetics and Diffusion with Single Particle
Sensitivity
N. Peerboom, E. Schmidt, Edward Trybala, S. Block, Thomas Bergström, H. P. Pace, M. Bally
Acs Infectious Diseases - 2018 -
Binding Kinetics and Lateral Mobility of HSV-1 on End-Grafted Sulfated
Glycosaminoglycans
N. Peerboom, S. Block, N. Altgarde, O. Wahlsten, S. Moller, M. Schnabelrauch, Edward Trybala, Tomas Bergström, M. Bally
Biophysical Journal - 2017 -
The Cholestanol-Conjugated Sulfated Oligosaccharide PG545 Disrupts the Lipid Envelope of Herpes Simplex Virus
Particles
Joanna Said, Edward Trybala, Staffan Görander, Maria Ekblad, Jan-Åke Liljeqvist, Eva Jennische, Stefan Lange, Tomas Bergström
Antimicrobial agents and chemotherapy - 2016 -
Mucin-like region of herpes simplex virus type 1 attachment protein gC modulates the virus-glycosaminoglycan
interaction.
Noomi Altgärde, Charlotta Eriksson, Nadia Peerboom, Tuan Phan-Xuan, Stephanie Möller, Matthias Schnabelrauch, Sofia Svedhem, Edward Trybala, Tomas Bergström, Marta Bally
Journal of Biological Chemistry - 2015 -
The anterior commissure is a pathway for contralateral spread of herpes simplex virus type 1 after olfactory tract
infection
Eva Jennische, Charlotta Eriksson, Stefan Lange, Edward Trybala, Tomas Bergström
Journal of Neurovirology - 2015 -
Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome
Virus
Anna Lundin, R. Dijkman, Tomas Bergström, Nina Kann, Beata Adamiak, Charles Hannoun, E. Kindler, H. R. Jonsdottir, D. Muth, J. Kint, M. Forlenza, M. A. Muller, C. Drosten, V. Thiel, Edward Trybala
Plos Pathogens - 2014 -
HIV-1 variants with reduced sensitivity to sulfated oligosaccharide muparfostat contain mutations in the envelope glycoproteins gp120 and
gp41
Joanna Said, Elin Andersson, Edward Trybala, Tomas Bergström
Journal of Antivirals and Antiretrovirals - 2013 -
Screening and evaluation of anti-respiratory syncytial virus compounds in cultured
cells.
Anna Lundin, Tomas Bergström, Edward Trybala
Antiviral Methods and Protocols. Ed. Edwin Yunhao Gong. (Methods in molecular biology, 1030) - 2013 -
Involvement of viral glycoprotein gC-1 in expression of the selectin ligand sialyl-Lewis X induced after infection with herpes simplex virus type
1.
Rickard Nordén, Kristina Nyström, Beata Adamiak, Adnan Halim, Jonas Nilsson, Göran Larson, Edward Trybala, Sigvard Olofsson
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 2013 -
Potent anti-respiratory syncytial virus activity of a cholestanol-sulfated tetrasaccharide
conjugate.
Anna Lundin, Tomas Bergström, Carla Regina Andrighetti-Fröhner, Loubna Bendrioua, Vito Ferro, Edward Trybala
Antiviral research - 2012 -
Human antibodies to herpes simplex virus type 1 glycoprotein C are neutralizing and target the heparan sulfate-binding
domain
Beata Adamiak, Edward Trybala, K. Mardberg, M. Johansson, Jan-Åke Liljeqvist, Sigvard Olofsson, A. Grabowska, K. Bienkowska-Szewczyk, B. Szewczyk, Tomas Bergström
Virology - 2010 -
Two novel fusion inhibitors of human respiratory syncytial
virus
Anna Lundin, Tomas Bergström, Loubna Bendrioua, Nina Kann, Beata Adamiak, Edward Trybala
Antiviral Research - 2010 -
Lipophile-conjugated sulfated oligosaccharides as novel microbicides against
HIV-1.
Joanna Said, Edward Trybala, Elin Andersson, Ken Johnstone, Ligong Liu, Norbert Wimmer, Vito Ferro, Tomas Bergström
Antiviral research - 2010 -
A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex
virus.
Maria Ekblad, Beata Adamiak, Tomas Bergström, Ken D Johnstone, Tomislav Karoli, Ligong Liu, Vito Ferro, Edward Trybala
Antiviral research - 2010 -
Evaluation of anti-HSV-2 activity of gallic acid and pentyl
gallate.
Jadel Müller Kratz, Carla Regina Andrighetti-Fröhner, Paulo César Leal, Ricardo José Nunes, Rosendo Augusto Yunes, Edward Trybala, Tomas Bergström, Célia Regina Barardi Monte, Cláudia Maria Oliveira Simões
Biological & pharmaceutical bulletin - 2008 -
Herpes simplex virus type 2 glycoprotein g is targeted by the sulfated oligo- and polysaccharide inhibitors of virus attachment to
cells
Beata Adamiak, Maria Ekblad, Tomas Bergström, Vito Ferro, Edward Trybala
Journal of Virology - 2007 -
Molecular basis for resistance of herpes simplex virus type 1 mutants to the sulfated oligosaccharide inhibitor
PI-88.
Maria Ekblad, Beata Adamiak, Kicki Bergefall, Hannah Nenonen, Anette Roth, Tomas Bergström, Vito Ferro, Edward Trybala
Virology - 2007 -
Chondroitin 4-O-sulfotransferase-1 regulates E disaccharide expression of chondroitin sulfate required for herpes simplex virus
infectivity.
Toru Uyama, Miho Ishida, Tomomi Izumikawa, Edward Trybala, Frank Tufaro, Tomas Bergström, Kazuyuki Sugahara, Hiroshi Kitagawa
The Journal of biological chemistry - 2006 -
Anti-herpes simplex virus activities of two novel disulphated
cyclitols.
Maria Ekblad, Tomas Bergström, Martin G Banwell, Muriel Bonnet, Jens Renner, Vito Ferro, Edward Trybala
Antiviral chemistry & chemotherapy - 2006 -
Chondroitin sulfate characterized by the E-disaccharide unit is a potent inhibitor of herpes simplex virus infectivity and provides the virus binding sites on gro2C
cells.
Kicki Bergefall, Edward Trybala, Maria Johansson, Toru Uyama, Satomi Naito, Shuhei Yamada, Hiroshi Kitagawa, Kazuyuki Sugahara, Tomas Bergström
The Journal of biological chemistry - 2005 -
The Synthesis and Biological Evaluation of Two Analogues of the C-Riboside
Showdomycin
Jens Renner, Irma Kruszelnicki, Beata Adamiak, Anthony C Willis, Edward Hammond, Stephen Su, Christopher Burns, Edward Trybala, Vito Ferro, Martin G Banwell
Australian Journal of Chemistry - 2005 -
Synthesis, biological activity, and preliminary pharmacokinetic evaluation of analogues of a phosphosulfomannan angiogenesis inhibitor
(PI-88).
Tomislav Karoli, Ligong Liu, Jon K Fairweather, Edward Hammond, Cai Ping Li, Siska Cochran, Kicki Bergefall, Edward Trybala, Russell S Addison, Vito Ferro
Journal of medicinal chemistry - 2005 -
Structural and functional features of the polycationic peptide required for inhibition of herpes simplex virus invasion of
cells.
Edward Trybala, Sigvard Olofsson, Kristina Mårdberg, Bo Svennerholm, Kimiko Umemoto, Joseph C Glorioso, Tomas Bergström
Antiviral research - 2004 -
Inhibition of herpes simplex virus infection by lactoferrin is dependent on interference with the virus binding to
glycosaminoglycans.
Magda Marchetti, Edward Trybala, Fabiana Superti, Maria Johansson, Tomas Bergström
Virology - 2004 -
Basic amino acids as modulators of an O-linked glycosylation signal of the herpes simplex virus type 1 glycoprotein gC: functional roles in viral
infectivity.
Kristina Mårdberg, Kristina Nyström, Mads Tarp Agervig, Edward Trybala, Henrik Clausen, Tomas Bergström, Sigvard Olofsson
Glycobiology - 2004 -
The low molecular weight heparan sulfate-mimetic, PI-88, inhibits cell-to-cell spread of herpes simplex
virus.
Kicki Nyberg, Maria Ekblad, Tomas Bergström, Craig Freeman, Christopher R Parish, Vito Ferro, Edward Trybala
Antiviral research - 2004