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Pentti Tengvall
Professor Emeritus
Department of BiomaterialsAbout Pentti Tengvall
Professor Pentti Tengvall started in 1986 his PhD-training in applied physics with professor Ingemar Lundström at Linköping university (LiTH) as the supervisor. After PhD in applied physics in 1989, he was employed as assistant professor at IFM, LiTH, he received a position as lecturer in biomaterials in 1994 and was promoted to full professor at LiTH in year 2000. He was awarded International Fellow of Biomaterials Science and Engineering (FBSE) in 2008. In 2008, he was recruited as Director of BIOSUM research school in Biomaterials and Cell Therapy at University of Gothenburg. Dr Tengvall has published 132 articles, many conference contributions and invited to many lectures and holds 5 patents/patent applications. He has supervised 15 PhD students.
Research interests: •Proteins at interfaces, interface modifications, and local drug delivery in bone implant applications.
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Osteoimmune regulation underlies oral implant osseointegration and its
perturbation
Tomas Albrektsson, Pentti Tengvall, L. Amengual, Pierluigi Coli, G. A. Kotsakis, D. Cochran
Frontiers in Immunology - 2023 -
Implications of considering peri-implant bone loss a disease, a narrative
review
Tomas Albrektsson, Pentti Tengvall, L. Amengual-Penafiel, Pierluigi Coli, Georgios Kotsakis, D. L. Cochran
Clinical Implant Dentistry and Related Research - 2022 -
An Imbalance of the Immune System Instead of a Disease Behind Marginal Bone Loss Around Oral Implants: Position
Paper
Tomas Albrektsson, Christer Dahlin, David Reinedahl, Pentti Tengvall, Ricardo Trindade, Ann Wennerberg
The International journal of oral & maxillofacial implants - 2020 -
The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood
reactivity
John L. Brash, Thomas A. Horbett, Robert A. Latour, Pentti Tengvall
Acta Biomaterialia - 2019 -
Bone Immune Response to Materials, Part II:Copper and Polyetheretherketone (PEEK) Compared to Titanium at 10 and 28 Days in Rabbit
Tibia
Ricardo Trindade, Tomas Albrektsson, S. Galli, Z. Prgomet, Pentti Tengvall, Ann Wennerberg
Journal of Clinical Medicine - 2019 -
On inflammation-immunological balance theory—A critical apprehension of disease concepts around implants: Mucositis and marginal bone loss may represent normal conditions and not necessarily a state of
disease
Tomas Albrektsson, Torsten Jemt, Johan Mölne, Pentti Tengvall, Ann Wennerberg
Clinical Implant Dentistry and Related Research - 2019 -
Aseptic Ligatures Induce Marginal Peri-Implant Bone Loss-An 8-Week Trial in
Rabbits.
David Reinedahl, Silvia Galli, Tomas Albrektsson, Pentti Tengvall, Carina B. Johansson, Petra Hammarström Johansson, Ann Wennerberg
Journal of clinical medicine - 2019 -
Bone Immune Response to Materials, Part I: Titanium, PEEK and Copper in Comparison to Sham at 10 Days in Rabbit
Tibia
Ricardo Trindade, Tomas Albrektsson, Silvia Galli, Zdenka Prgomet, Pentti Tengvall, Ann Wennerberg
Journal of Clinical Medicine - 2018 -
Effects of implant-delivered insulin on bone formation in osteoporotic
rats
Behnosh Öhrnell Malekzadeh, Malin Erlandsson, Pentti Tengvall, Anders Palmquist, Maria Ransjö, Maria Bokarewa, Anna Westerlund
Journal of Biomedical Materials Research - Part A - 2018 -
Ligature-Induced Experimental Peri-Implantitis—A Systematic
Review
David Reinedahl, Bruno Chrcanovic, Tomas Albrektsson, Pentti Tengvall, Ann Wennerberg
MDPI Journal of Clinical Medicine - 2018 -
Titanium granules pre-treated with hydrogen peroxide inhibit growth of bacteria associated with post-operative infections in spine
surgery
Acke Ohlin, Emma Mattsson, Matthias Mörgelin, Julia R. Davies, Gunnel Svensäter, Stéphane Corvec, Pentti Tengvall, Kristian Riesbeck
European Spine Journal - 2018 -
Osseointegration and foreign body reaction: Titanium implants activate the immune system and suppress bone resorption during the first 4 weeks after
implantation
Ricardo Trindade, Tomas Albrektsson, Silvia Galli, Zdenka Prgomet, Pentti Tengvall, Ann Wennerberg
Clinical Implant Dentistry and Related Research - 2018 -
Insulin released from titanium discs with insulin coatings- kinetics and biological
activity
Behnosh Öhrnell Malekzadeh, Maria Ransjö, Pentti Tengvall, Zivko Mladenović, Anna Westerlund
Journal of Biomedical Materials Research. Part B - Applied biomaterials - 2017 -
Surface characterization of insulin-coated Ti6Al4V medical implants conditioned in cell culture medium: An XPS
study
Andrey Shchukarev, Behnosh Öhrnell Malekzadeh, Maria Ransjö, Pentti Tengvall, Anna Westerlund
Journal of Electron Spectroscopy and Related Phenomena - 2017 -
Foreign Body Reaction to Biomaterials: On Mechanisms for Buildup and Breakdown of
Osseointegration.
Ricardo Trindade, Tomas Albrektsson, Pentti Tengvall, Ann Wennerberg
Clinical implant dentistry and related research - 2016 -
Stem cell homing using local delivery of plerixafor and stromal derived growth factor-1alpha for improved bone regeneration around
Ti-implants
Johan Karlsson, Necati Harmankaya, Anders Palmquist, Saba Atefyekta, Omar Omar, Pentti Tengvall, Martin Andersson
Journal of Biomedical Materials Research. Part A - 2016 -
Ex vivo alendronate localization at the mesoporous titania implant/bone
interface
Johan Karlsson, Necati Harmankaya, Stefan Allard, Anders Palmquist, Mats Halvarsson, Pentti Tengvall, Martin Andersson
Journal of materials science. Materials in medicine - 2015 -
Madindoline A Affects the Osteogenic Potential and the Wnt
Signaling
Anna Thorfve, Emilia Svala, Helena Brisby, Peter Thomsen, Anders Lindahl, Pentti Tengvall
Journal of Bone Marrow Research - 2014 -
Localized controlled drug delivery from mesoporous
implants
Johan Karlsson, Necati Harmankaya, Anders Palmquist, Ryo Jimbo, Anna Martinelli, Gustav Sundell, Mattias Thuvander, Mats Halvarsson, Pentti Tengvall, Martin Andersson
Technical Proceedings of the 2014 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2014. Washington, DC, United States, 15-18 June 2014 - 2014 -
Gene Expression Profiling of Peri-Implant Healing of PLGA-Li+ Implants Suggests an Activated Wnt Signaling Pathway In
Vivo
Anna Thorfve, Anna Bergstrand, Karin Ekström, Anders Lindahl, Peter Thomsen, Anette Larsson, Pentti Tengvall
Plos One - 2014 -
Response: Platelets do not generate activated factor XII-how inappropriate experimental models have led to misleading
conclusions.
Niklas Boknäs, Lars Faxälv, Jakob O Ström, Pentti Tengvall, Elvar Theodorsson, Sofia Ramström, Tomas L Lindahl
Blood - 2014 -
Hydroxyapatite coating affects the Wnt signaling pathway during peri-implant healing in
vivo
Anna Thorfve, Carl Lindahl, Wei Xia, Kazuyo Igawa, Anders Lindahl, Peter Thomsen, Anders Palmquist, Pentti Tengvall
Acta Biomaterialia - 2014 -
Effects of locally administered insulin on bone formation in non-diabetic
rats.
Benoosh Malekzadeh, Pentti Tengvall, Lars-Olov Öhrnell, Ann Wennerberg, Anna Westerlund
Journal of biomedical materials research. Part A - 2013 -
Putting polyphosphates to the test: evidence against platelet-induced activation of factor
XII.
Lars Faxälv, Niklas Boknäs, Jakob O Ström, Pentti Tengvall, Elvar Theodorsson, Sofia Ramström, Tomas L Lindahl
Blood - 2013 -
Bone Response to Surface-Modified Titanium Implants: Studies on the Early Tissue Response to Implants with Different Surface
Characteristics
Cecilia Larsson Wexell, Peter Thomsen, Björn-Owe Aronsson, Pentti Tengvall, Michael Rodahl, Jukka Lausmaa, Bengt Kasemo, Lars Ericson
International Journal of Biomaterials - 2013 -
Raloxifene and alendronate containing thin mesoporous titanium oxide films improve implant fixation to
bone.
Necati Harmankaya, Johan Karlsson, Anders Palmquist, Mats Halvarsson, K Igawa, Martin Andersson, Pentti Tengvall
Acta biomaterialia - 2013 -
Histologic analysis of a novel extracellullar matrix membrane for guided bone regeneration: an experimental study in
rabbits.
Adel Al-Asfour, Pentti Tengvall, Lars Andersson, Christer Dahlin
The International journal of periodontics & restorative dentistry - 2013 -
Local bisphosphonate release versus hydroxyapatite coating for stainless steel screw fixation in rat
tibiae.
F Agholme, T Andersson, Pentti Tengvall, P Aspenberg
Journal of materials science: Materials in medicine - 2012 -
Inhibition of canonical Wnt signaling pathway by DKK1 induces increased ALP activity in hMSC in
vitro.
Anna Thorfve, Anders Lindahl, Peter Thomsen, C Karlsson, Pentti Tengvall
Abstract, 9th World Biomaterials Congress, Chengdu, China. - 2012 -
Healing of complement activating Ti implants compared with non-activating Ti in rat
tibia.
Necati Harmankaya, K Igawa, P Stenlund, Anders Palmquist, Pentti Tengvall
Acta biomaterialia - 2012 -
A bisphosphonate-coating improves the fixation of metal implants in human bone. A randomized trial of dental
implants.
Jahan Abtahi, Pentti Tengvall, Per Aspenberg
Bone - 2012 -
Weak effect of strontium on early implant fixation in rat
tibia.
Paula Linderbäck, Fredrik Agholme, Karin Wermelin, Timo Närhi, Pentti Tengvall, Per Aspenberg
Bone - 2012 -
In vitro response to mesoporous TiO2 thin films loaded with alendronate and
raloxifene
N. Harmankaya, Johan Karlsson, Anders Palmquist, Mats Halvarsson, Martin Andersson, Pentti Tengvall
In vitro response to mesoporous TiO2 thin films loaded with alendronate and raloxifene - 2011 -
Cell expansion of human articular chondrocytes on macroporous gelatine scaffolds-impact of microcarrier selection on cell
proliferation.
Sofia Pettersson, Jonas Wetterö, Pentti Tengvall, Gunnar Kratz
Biomedical materials - 2011 -
Laminin Coating Promotes Calcium Phosphate Precipitation on Titanium Discs in
vitro.
Kostas Bougas, Victoria Franke Stenport, Pentti Tengvall, Fredrik Currie, Ann Wennerberg
Journal of Oral & Maxillofacial Research - 2011 -
Protein adsorption on thin films of carbon and carbon nitride monitored with in situ
ellipsometry.
T Berlind, Pentti Tengvall, L Hultman, H Arwin
Acta biomaterialia - 2011 -
Protein adsorption to
biomaterials.
Pentti Tengvall
Comprehensive biomaterials. Eds: Ducheyne P, Healy KE, Hutmacher DE, Grainger DE, Kirkpatrick CJ. - 2011 -
An auto-catalytic surface for conformational replication of amyloid fibrils--genesis of an amyloid
world?
Per Hammarström, Malik M Ali, Rajesh Mishra, Belma Salagic, Samuel Svensson, Pentti Tengvall, Ingemar Lundström
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life - 2011 -
Bisphosphonate coating might improve fixation of dental implants in the maxilla: A pilot
study
Jahan Abtahi, Pentti Tengvall, Per Aspenberg
International Journal of Oral and Maxillofacial Surgery - 2010 -
C1q induces a rapid up-regulation of P-selectin and modulates collagen- and collagen-related peptide-triggered activation in human
platelets.
Caroline Skoglund, Jonas Wetterö, Pentti Tengvall, Torbjörn Bengtsson
Immunobiology - 2010 -
Sol-gel derived titania coating with immobilized bisphosphonate enhances screw fixation in rat
tibia.
Paula Linderbäck, Sami Areva, Per Aspenberg, Pentti Tengvall
Journal of biomedical materials research. Part A - 2010 -
The ability of surface characteristics of materials to trigger leukocyte tissue factor
expression.
Marion Fischer, Claudia Sperling, Pentti Tengvall, Carsten Werner
Biomaterials - 2010 -
Formation and cross-linking of fibrinogen layers monitored with in situ spectroscopic
ellipsometry.
T Berlind, M Poksinski, Pentti Tengvall, H Arwin
Colloids and surfaces. B, Biointerfaces - 2010 -
Surface immobilized zoledronate improves screw fixation in rat bone: A new method for the coating of metal
implants.
Therese Andersson, Fredrik Agholme, Per Aspenberg, Pentti Tengvall
Journal of materials science. Materials in medicine - 2010 -
The effect of heat- or ultra violet ozone-treatment of titanium on complement deposition from human blood
plasma.
Paula Linderbäck, Necati Harmankaya, Agneta Askendal, Sami Areva, Jukka Lausmaa, Pentti Tengvall
Biomaterials - 2010 -
Human articular chondrocytes on macroporous gelatin microcarriers form structurally stable constructs with blood-derived biological glues in
vitro.
Sofia Pettersson, Jonas Wetterö, Pentti Tengvall, Gunnar Kratz
Journal of tissue engineering and regenerative medicine - 2009 -
Blood interactions with noble metals: coagulation and immune complement
activation.
Mats Hulander, Jaan Hong, Marcus Andersson, Frida Gervén, Mattias Ohrlander, Pentti Tengvall, Hans-Björne Elwing
ACS applied materials & interfaces - 2009 -
Glycerol monooleate-blood
interactions
Emma Ericsson, Lars Faxälv, Anna Weissenrieder, Agneta Askendal, Tomas L Lindahl, Pentti Tengvall
Colloids And Surfaces B-Biointerfaces - 2009 -
Stainless steel screws coated with bisphosphonates gave stronger fixation and more surrounding bone. Histomorphometry in
rats.
K Wermelin, Felicia Suska, Pentti Tengvall, Peter Thomsen, P Aspenberg
Bone - 2008 -
Fibrous capsule formation around titanium and
copper.
Felicia Suska, Lena Emanuelsson, Anna Johansson, Pentti Tengvall, Peter Thomsen
Journal of Biomedical Materials Research Part A - 2008 -
Bisphosphonate coating on titanium screws increases mechanical fixation in rat tibia after two
weeks.
Karin Wermelin, Per Aspenberg, Paula Linderbäck, Pentti Tengvall
Journal of biomedical materials research. Part A - 2008 -
Detection of surface bound complement at increasing serum anticoagulant
concentrations.
S Arvidsson, A Askendal, T L Lindahl, Pentti Tengvall
Colloids and surfaces. B, Biointerfaces - 2008 -
Imaging of blood plasma coagulation and its propagation at
surfaces.
Lars Faxälv, Pentti Tengvall, Tomas L Lindahl
Journal of biomedical materials research. Part A - 2008 -
Doxycycline-coated sutures improve mechanical strength of intestinal
anastomoses.
Björn Pasternak, Martin Rehn, Line Andersen, M S Agren, Anne-Marie Heegaard, Pentti Tengvall, Per Aspenberg
International journal of colorectal disease - 2008 -
C-reactive protein and C1q regulate platelet adhesion and activation on adsorbed immunoglobulin G and
albumin.
Caroline Skoglund, Jonas Wetterö, Thomas Skogh, Christopher Sjöwall, Pentti Tengvall, Torbjörn Bengtsson
Immunology and cell biology - 2008 -
Control of neural stem cell adhesion and density by an electronic polymer surface
switch.
Carmen Saltó, Emilien Saindon, Maria Bolin, Anna Kanciurzewska, Mats Fahlman, Edwin W H Jager, Pentti Tengvall, Ernest Arenas, Magnus Berggren
Langmuir : the ACS journal of surfaces and colloids - 2008 -
Inflammatory response to titanium surfaces with fibrinogen and catalase coatings: an in vitro
study
Anna Göransson, Christina Gretzer, Pentti Tengvall, Ann Wennerberg
J Biomed Mater Res A - 2007 -
Inflammatory response to titanium surfaces with fibrinogen and catalase coatings: an in vitro
study.
Anna Göransson, Christina Gretzer, Pentti Tengvall, Ann Wennerberg
Journal of biomedical materials research. Part A - 2007 -
Solid-phase classical complement activation by C-reactive protein (CRP) is inhibited by fluid-phase CRP-C1q
interaction.
Christopher Sjöwall, Jonas Wetterö, Torbjörn Bengtsson, Agneta Askendal, Gunnel Almroth, Thomas Skogh, Pentti Tengvall
Biochemical and biophysical research communications - 2007 -
Blood plasma contact activation on silicon, titanium and
aluminium.
Sara Arvidsson, Agneta Askendal, Pentti Tengvall
Biomaterials - 2007 -
Surface plasmon resonance detection of blood coagulation and platelet adhesion under venous and arterial shear
conditions.
Kenny M Hansson, Knut Johansen, Jonas Wetterö, Goran Klenkar, Johan Benesch, Ingemar Lundström, Tomas L Lindahl, Pentti Tengvall
Biosensors & bioelectronics - 2007 -
Surface-bound bisphosphonates enhance screw fixation in rats--increasing effect up to 8 weeks after
insertion.
Karin Wermelin, Pentti Tengvall, Per Aspenberg
Acta orthopaedica - 2007 -
Doxycycline-coated sutures improve the suture-holding capacity of the rat Achilles
tendon.
Björn Pasternak, Anna Missios, Agneta Askendal, Pentti Tengvall, Per Aspenberg
Acta orthopaedica - 2007 -
Platelet-induced growth of human fibroblasts is associated with an increased expression of
5-lipoxygenase.
Cecilia Berg, Sven Hammarström, Helena Herbertsson, Eva Lindström, Ann-Charlotte Svensson, Mats Söderström, Pentti Tengvall, Torbjörn Bengtsson
Thrombosis and haemostasis - 2006 -
Monocyte viability on titanium and copper coated
titanium.
Felicia Suska, Christina Gretzer, Marco Esposito, Pentti Tengvall, Peter Thomsen
Biomaterials - 2005 -
In vivo cytokine secretion and NF-kappaB activation around titanium and copper
implants.
Felicia Suska, Christina Gretzer, Marco Esposito, Lena Emanuelsson, Ann Wennerberg, Pentti Tengvall, Peter Thomsen
Biomaterials - 2005 -
Whole blood coagulation on protein adsorption-resistant PEG and peptide functionalised PEG-coated titanium
surfaces.
Kenny M Hansson, Samuele Tosatti, Joakim Isaksson, Jonas Wetterö, Marcus Textor, Tomas L Lindahl, Pentti Tengvall
Biomaterials - 2005 -
Anti-inflammatory effects of a titanium-peroxy gel: role of oxygen metabolites and
apoptosis.
Jenny Larsson, C. Persson, Pentti Tengvall, Helen Lundqvist-Gustafsson
Journal of biomedical materials research. Part A - 2004 -
Differences in early apoptosis/cell death on titanium and copper in
vitro.
Felicia Suska, Christina Gretzer, Marco Esposito, Pentti Tengvall, Peter Thomsen
Abstract, 7th World Biomaterials Congress, Sydney, Australia, 2004 - 2004 -
Surface immobilized bisphosphonate improves stainless-steel screw fixation in
rats.
Pentti Tengvall, B Skoglund, A Askendal, P Aspenberg
Biomaterials - 2004 -
Adsorption of albumin and IgG to porous and smooth
titanium.
Eva Jansson, Pentti Tengvall
Colloids and surfaces. B, Biointerfaces - 2004 -
The determination of thickness and surface mass density of mesothick immunoprecipitate layers by null ellipsometry and protein 125iodine
labeling.
Johan Benesch, Agneta Askendal, Pentti Tengvall
Journal of colloid and interface science - 2002 -
In vivo/ex vivo cellular interactions with titanium and
copper.
Felicia Suska, Mia Källtorp, Marco Esposito, Christina Gretzer, Pentti Tengvall, Peter Thomsen
Journal of materials science. Materials in medicine - 2001 -
On the formation of fibrous capsule and fluid space around machined and porous blood plasma clot coated
titanium.
E Jansson, Mia Källtorp, Anna Johansson, Pentti Tengvall, Peter Thomsen
Journal of materials science. Materials in medicine - 2001 -
Analysis of rat plasma proteins desorbed from gold and methyl- and hydroxyl-terminated alkane thiols on gold
surfaces.
Mia Källtorp, Anette Carlén, Peter Thomsen, Jan Olsson, Pentti Tengvall
Journal of materials science. Materials in medicine - 2000 -
In vivo cell recruitment, cytokine release and chemiluminescence response at gold, and thiol functionalized
surfaces.
Mia Källtorp, S Oblogina, Stefan Jacobsson, Anna Karlsson, Pentti Tengvall, Peter Thomsen
Biomaterials - 1999