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Karin Ekström
Researcher
Department of SurgeryAbout Karin Ekström
Karin Ekström did her undergraduate and graduate training at the University of Gothenburg, earning a medicine master in pharmaceutical bioscience in 2004. Karin Ekström received her PhD at the University of Gothenburg in 2008 with the thesis "Exosomal Shuttle RNA" where she made major contributions establishing the functional mechanisms of exosomes in cell-cell communication. Between 2009 and 2019 Karin Ekström worked as a post doc and researcher at the Department of Biomaterials at the University of Gothenburg studying EVs in the field of inflammation, regeneration and biomaterials. Currently, Karin Ekström is working at the Department of Surgery, focusing her research on the role of exosomes in cancer
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Immunomodulatory effects exerted by extracellular vesicles from Staphylococcus epidermidis and Staphylococcus aureus isolated from bone-anchored
prostheses
Magdalena Zaborowska, Forugh Vazirisani, Furqan A. Shah, Rininta Firdaus, Omar Omar, Karin Ekström, Margarita Trobos, Peter Thomsen
Biomaterials - 2021 -
Exosomes influence the behavior of human mesenchymal stem cells on titanium
surfaces.
Xiaoqin Wang, Furqan A. Shah, Forugh Vazirisani, Anna Johansson, Anders Palmquist, Omar Omar, Karin Ekström, Peter Thomsen
Biomaterials - 2020 -
Future Perspectives of Bone Tissue Engineering with Special Emphasis on Extracellular
Vesicles
Sippy Kaur, Bettina Mannerström, Karin Ekström, Riitta Seppänen-Kaijansinkko
Tissue Engineering in Oral and Maxillofacial Surgery. Seppänen-Kaijansinkko R. (red.) - 2019 -
The impact of in vitro ageing on the release of extracellular vesicles from human mesenchymal stem
cells
Xiaoqin Wang, Jincy Philip, Forugh Vazirisani, Chrysoula Tsirigoti, Peter Thomsen, Karin Ekström
8th Annual Meeting of the International Society for Extracellular Vesicles (ISEV2019), Kyoto, Japan. Abstract Book. Journal of Extracellular Vesicles. Vol. 8, suppl. 1 - 2019 -
Interactions between monocytes, mesenchymal stem cells, and implants evaluated using flow cytometry and gene
expression
Maria Lennerås, Karin Ekström, Forugh Vazirisani, Furqan A. Shah, K. Junevik, Peter Thomsen, Omar Omar
Journal of Tissue Engineering and Regenerative Medicine - 2018 -
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014
guidelines
C. Thery, K. W. Witwer, E. Aikawa, A. P. D. Rubio, Karin Ekström, Ganesh V Shelke, Maugeri Marco, Muhammad Nawaz, Rossella Crescitelli, Cecilia Lässer, Jan Lötvall, Jessica Wahlgren
Journal of Extracellular Vesicles - 2018 -
Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of
differentiation
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Peter Thomsen, Karin Ekström
PLoS ONE - 2018 -
Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue
Regeneration
Farah Fatima, Karin Ekström, Irina Nazarenko, Maugeri Marco, Hadi Valadi, Andrew F. Hill, Giovanni Camussi, Muhammad Nawaz
Frontiers in Genetics - 2017 -
Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker
discovery
Muhammad Nawaz, Farah Fatima, I. Nazarenko, Karin Ekström, I. Murtaza, M. Anees, A. Sultan, L. Neder, G. Camussi, Hadi Valadi, J. A. Squire, T. Kislinger
Expert Review of Proteomics - 2016 -
Altered microRNA expression profile in exosomes derived from mesenchymal stem cells during osteogenic
differentiation
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Peter Thomsen, Karin Ekström
European Cells and Materials - 2016 -
Extracellular vesicles from gram-positive bacteria Staphylococcus aureus and Staphylococcus epidermidis induce a strong inflammatory response and cell death in
vitro
Forugh Vazirisani, Margarita Trobos, Magdalena Zaborowska, Xiaoqin Wang, Omar Omar, Karin Ekström, Peter Thomsen
ISEV 2016, Rotherdam, Netherlands - 2016 -
Extracellular Vesicles: Evolving Factors in Stem Cell
Biology
Muhammad Nawaz, Farah Fatima, Krishna C. Vallabhaneni, Patrice Penfornis, Hadi Valadi, Karin Ekström, Sharad Kholia, Jason D.Whitt, Joseph D. Fernandes, Radhika Pochampally, Jeremy A. Squire, Giovanni Camussi
Stem Cells International - 2016 -
EVpedia: A Community Web Portal for Extracellular Vesicles
Research
Dae-Kyum Kim, Jaewook Lee, Sae Rom Kim, Dong-Sic Choi, Yae Jin Yoon, Ji Hyun Kim, Gyeongyun Go, Dinh Nhung, Kahye Hong, Su Chul Jang, Si-Hyun Kim, Kyong-Su Park, Oh Youn Kim, Hyun Taek Park, Ji Hye Seo, Elena Aikawa, Monika Baj-Krzyworzeka, Bas W. M. van Balkom, Mattias Belting, Lionel Blanc, Vincent Bond, Antonella Bongiovanni, Francesc E. Borràs, Luc Buée, Edit I. Buzás, Lesley Cheng, Aled Clayton, Emanuele Cocucci, Charles S. Dela Cruz, Dominic M. Desiderio, Dolores Di Vizio, Karin Ekström, Juan M. Falcon-Perez, Chris Gardiner, Bernd Giebel, David W. Greening, Julia Christina Gross, Dwijendra Gupta, An Hendrix, Andrew F. Hill, Michelle M. Hill, Esther Nolte-'t Hoen, Do Won Hwang, Jameel Inal, Medicharla V. Jagannadham, Muthuvel Jayachandran, Young-Koo Jee, Malene Jørgensen, Kwang Pyo Kim, Yoon-Keun Kim, Thomas Kislinger, Cecilia Lässer, Dong Soo Lee, Hakmo Lee, Johannes van Leeuwen, Thomas Lener, Ming-Lin Liu, Jan Lötvall, Antonio Marcilla, Suresh Mathivanan, Andreas Möller, Jess Morhayim, François Mullier, Irina Nazarenko, Rienk Nieuwland, Diana N. Nunes, Ken Pang, Jaesung Park, Tushar Patel, Gabriella Pocsfalvi, Hernando del Portillo, Ulrich Putz, Marcel I. Ramirez, Marcio L. Rodrigues, Tae-Young Roh, Felix Royo, Susmita Sahoo, Raymond Schiffelers, Shivani Sharma, Pia Siljander, Richard J. Simpson, Carolina Soekmadji, Philip Stahl, Allan Stensballe, Ewa Stępień, Hidetoshi Tahara, Arne Trummer, Hadi Valadi, Laura J. Vella, Sun Nyunt Wai, Kenneth Witwer, María Yáñez-Mó, Hyewon Youn, Reinhard Zeidler, Yong Song Gho
Bioinformatics - 2015 -
Mesenchymal stem cells and monocytes communicate via
exosomes
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Peter Thomsen, Karin Ekström
MedTech and Biomaterials, Gothenburg, Sweden, March 4 2014 - 2014 -
Exosomes derived from mesenchymal stem cells during osteogenic differentiation induce osteogenic differentiation of mesenchymal stem
cells
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Peter Thomsen, Karin Ekström
International Society of Extracellular Vesicles, Rotterdam, The Netherlands, April 30 – May3 2014 - 2014 -
Gene Expression Profiling of Peri-Implant Healing of PLGA-Li+ Implants Suggests an Activated Wnt Signaling Pathway In
Vivo
Anna Thorfve, Anna Bergstrand, Karin Ekström, Anders Lindahl, Peter Thomsen, Anette Larsson, Pentti Tengvall
Plos One - 2014 -
Osteogenic response of human mesenchymal stem cells to well-defined nanoscale topography in
vitro
Giuseppe Maria de Peppo, Hossein Agheli, Camilla Karlsson, Karin Ekström, Helena Brisby, Maria Lennerås, Stefan Gustafsson, Peter Sjövall, Anna Johansson, Eva Olsson, J. Lausmaa, Peter Thomsen, S. Petronis
International Journal of Nanomedicine - 2014 -
The emerging role of extracellular vesicles as biomarkers for urogenital
cancers.
Muhammad Nawaz, Giovanni Camussi, Hadi Valadi, Irina Nazarenko, Karin Ekström, Xiaoqin Wang, Simona Principe, Neelam Shah, Naeem M Ashraf, Farah Fatima, Luciano Neder, Thomas Kislinger
Nature reviews. Urology - 2014 -
The effect of membrane vesicles from Staphylococcus aureus and Staphylococcus epidermidis on monocytes and
macrophages
Forugh Vazirisani, Margarita Trobos, Xiaoqin Wang, Zivko Mladenović, Anders Palmquist, Omar Omar, Karin Ekström, Peter Thomsen
Second International Meeting of ISEV (International Society for Extracellular Vesicles) 2013, April 17-20, Boston, USA. Abstracts - 2013 -
Monocyte Exosomes Stimulate the Osteogenic Gene Expression of Mesenchymal Stem
Cells
Karin Ekström, Omar Omar, Cecilia Granéli, Xiaoqin Wang, Forugh Vazirisani, Peter Thomsen
Plos One - 2013 -
Mesenchymal stem cell-derived exosomes interact with monocytes and mesenchymal stem
cells
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Zivko Mladenović, Peter Thomsen, Karin Ekström
Second International Meeting of ISEV (International Society for Extracellular Vesicles) 2013, April 17-20, Boston, USA. Abstracts - 2013 -
Monocytes and mesenchymal stem cells internalize mesenchymal stem cell-derived
exosomes
Xiaoqin Wang, Omar Omar, Forugh Vazirisani, Zivko Mladenović, Peter Thomsen, Karin Ekström
Abstract, Materials for Tomorrow, Gothenburg, Sweden - 2013 -
Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor
cells
Karin Ekström, Hadi Valadi, Margareta Sjöstrand, Carina Malmhäll, Apostolos Bossios, Maria Eldh, Jan Lötvall
Journal of Extracellular Vesicles (JEV) - 2012 -
Monocyte exosomes induce osteogenic gene expression of mesenchymal stem
cells.
Karin Ekström, Forugh Vazirisani, Xiaoqin Wang, Omar Omar, Peter Thomsen
Abstract, Materials for Tomorrow, Chalmers, Gothenburg, Sweden. - 2012 -
The role of cell-cell communication for the transition from inflammation to bone
regeneration.
Peter Thomsen, Omar Omar, Giuseppe Maria de Peppo, Karin Ekström
Abstract, Invited key-note lecture, TERMIS, Vienna, Austria. September, 5-8 - 2012 -
Influence of Classical Versus Alternatively Activated Monocytes on the Osteogenic Gene Expression of Human Mesenchymal Stem
Cells
Cecilia Granéli, Omar Omar, Karin Ekström, Anna Johansson, Camilla Karlsson, Peter Thomsen
9th World Biomaterials Congress June 1-5, 2012, Chengdu, China. - 2012 -
Monocytes Release Exosomes that Stimulate Osteogenic Gene Expression of Mesenchymal Stem
Cells
Karin Ekström, Omar Omar, Cecilia Granéli, Michaela Johansson, Anna Johansson, Peter Thomsen
9th World Biomaterials Congress June 1-5, 2012, Chengdu, China - 2012 -
Importance of RNA isolation methods for analysis of exosomal RNA: Evaluation of different
methods
Maria Eldh, Jan Lötvall, Carina Malmhäll, Karin Ekström
Molecular Immunology - 2012 -
The stimulation of an osteogenic response by classical monocyte
activation.
Omar Omar, Cecilia Granéli, Karin Ekström, Camilla Karlsson, Anna Johansson, Jukka Lausmaa, Cecilia Larsson Wexell, Peter Thomsen
Biomaterials - 2011 -
Human saliva, plasma and breast milk exosomes contain RNA: uptake by
macrophages.
Cecilia Lässer, Vesta Seyed Alikhani, Karin Ekström, Maria Eldh, Patricia Torregrosa Paredes, Apostolos Bossios, Margareta Sjöstrand, Susanne Gabrielsson, Jan Lötvall, Hadi Valadi
Journal of Translational Medicine - 2011 -
RNA-containing exosomes in human nasal
secretions.
Cecilia Lässer, Serena O'Neil, Linda Ekerljung, Karin Ekström, Margareta Sjöstrand, Jan Lötvall
American journal of rhinology & allergy - 2011 -
Exosomes Communicate Protective Messages during Oxidative Stress; Possible Role of Exosomal Shuttle
RNA.
Maria Eldh, Karin Ekström, Hadi Valadi, Margareta Sjöstrand, Bob Olsson, Margareta Jernås, Jan Lötvall
PloS one - 2010 -
Exosomal Shuttle
RNA
Karin Ekström
2008 -
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between
cells.
Hadi Valadi, Karin Ekström, Apostolos Bossios, Margareta Sjöstrand, James J Lee, Jan Lötvall
Nature cell biology - 2007