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- Wei-Yun Lai
Wei-Yun Lai
Researcher
Department of Medical Biochemistry and Cell biology-
Anaplastic Lymphoma Kinase signaling stabilizes SLC3A2 expression via MARCH11 to promote neuroblastoma cell
growth
Wei-Yun Lai, Tzu-Po Chuang, Marcus Borenäs, Dan E. Lind, Bengt Hallberg, Ruth H. Palmer
CELL DEATH AND DIFFERENTIATION - 2024 -
ALK signaling primes the DNA damage response sensitizing ALK-driven neuroblastoma to therapeutic ATR
inhibition
Marcus Borenäs, Ganesh Umapathy, Dan E. Lind, Wei-Yun Lai, Jikui Guan, Joel Johansson, Eva Jennische, Alexander Schmidt, Yeshwant Kurhe, Jonatan L. Gabre, Agata Aniszewska, Anneli Strömberg, Mats Bemark, Michael N. Hall, Jimmy Van den Eynden, Bengt Hallberg, Ruth H. Palmer
Proceedings of the National Academy of Sciences of the United States of America - 2024 -
ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4
expression
Tzu-Po Chuang, Wei-Yun Lai, Jonatan L. Gabre, Dan E. Lind, Ganesh Umapathy, Abdulmalik Bokhari, Bengt Bergman, Linnea Kristenson, Fredrik Bergh Thorén, Anh Le, Robert C. Doebele, Jimmy Van den Eynden, Ruth H. Palmer, Bengt Hallberg
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA - 2023 -
IGF1R Contributes to Cell Proliferation in ALK-Mutated Neuroblastoma with Preference for Activating the PI3K-AKT Signaling
Pathway.
Jikui Guan, Marcus Borenäs, Junfeng Xiong, Wei-Yun Lai, Ruth H. Palmer, Bengt Hallberg
Cancers - 2023 -
Novel human-derived EML4-ALK fusion cell lines identify ribonucleotide reductase RRM2 as a target of activated ALK in
NSCLC
Abdulmalik Bokhari, Wei-Yun Lai, A. T. Le, Jonatan L. Gabre, Tzu-Po Chuang, Susanne Fransson, B. Bergman, Anna Djos, N. Chen, Tommy Martinsson, J. Van den Eynden, R. C. Doebele, Ruth H. Palmer, Bengt Hallberg, Ganesh Umapathy
Lung Cancer - 2022 -
ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK
mutation.
Marcus Borenäs, Ganesh Umapathy, Wei-Yun Lai, Dan E. Lind, Barbara Witek, Jikui Guan, Patricia Mendoza-García, Tafheem Masudi, Arne Claeys, Tzu-Po Chuang, Abeer El Wakil, Badrul Arefin, Susanne Fransson, Jan Koster, Mathias Johansson, Jennie Gaarder, Jimmy Van den Eynden, Bengt Hallberg, Ruth H. Palmer
The EMBO journal - 2021 -
11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in
Neuroblastoma
Joachim T. Siaw, Niloufar Javanmardi, Jimmy Van den Eynden, Dan E. Lind, Susanne Fransson, Angela Martinez-Monleon, Anna Djos, Rose-Marie Sjöberg, Malin Östensson, H. Caren, G. Troen, K. Beiske, A. P. Berbegall, R. Noguera, Wei-Yun Lai, P. Kogner, Ruth H. Palmer, Bengt Hallberg, Tommy Martinsson
Cell Reports - 2020