EATRIS Center for Large-scale cell-based screening
The center is an official node of EATRIS (European infrastructure for translational medicine), it provides access to various high throughput methodologies for genome-wide screens. This unit is of importance for a wide array of applications in cell and molecular biology, microbial evolution, drug/antibiotics screening and biotechnology.
The infrastructure consists of robots and automated phenotyping devices that are used in genome-wide approaches in many fields of bioscience. Software and databases have been developed for data generation, analysis, storage and presentation. Moreover, existing massive microbial strain collections are a fundament of the screening services that the infrastructure delivers.
Instrument and booking information
- ImageXpress MICRO (MDC), automated cellular imaging and analysis system.
- MICROLAB STAR Line (Hamilton), large scale liquid handling robotic system.
- Synergy 2 Multi-Mode Microplate Reader (BioTek), to detect the cell density.
- Singer RoToR HDA (Singer Instrument), automated large-scale SGA analysis robot, to integrate reporters into different strain collections by cross recombination.
- Bioscreen C (OY Growth Curves AB), automated high throughput growth screening analysis.
- Flow cytometer, FACS Aria, BD equipment.
Services and prices
Acknowledgement of the ECLCS in Publications
Acknowledgements are of great importance to the ECLCS, as publications by our users are an important indicator of the impact and importance of the infrastructure. They demonstrate to university managers and research networks the effective use of ECLCS resources and are a prerequisite for the success of the ECLCS in evaluation processes and grant applications.
If you use data collected, analysed or processed at the ECLCS in a publication or in a grant application, the ECLCS should be acknowledged. For example: “We acknowledge the EATRIS Center for Large-scale Cell-based Screening at the University of Gothenburg for performing/assisting with the high content imaging based genetic/drug/compound/chemical screening.” Publications include, but are not limited to, scientific papers, theses as well as conference contributions.