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- Ville Wallenius
Ville Wallenius
Professor, adjungerad
Avd för kirurgi-
Intestinal Ketogenesis and
Permeability
Anna Casselbrant, Erik Elias, Peter Hallersund, Erik Elebring, Jakob Cervin, Lars Fändriks, Ville Wallenius
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - 2024 -
Role of FFAR3 in ketone body regulated glucagon-like peptide 1
secretion
Sara M.T. Persson, Anna Casselbrant, Aiham Alarai, Erik Elebring, Lars Fändriks, Ville Wallenius
BIOCHEMISTRY AND BIOPHYSICS REPORTS - 2024 -
βHB inhibits glucose-induced GLP-1 secretion in GLUTag and human jejunal
enteroids
Erik Elebring, Anna Casselbrant, Sara M.T. Persson, Lars Fändriks, Ville Wallenius
Journal of molecular endocrinology - 2023 -
Resolution of diabetes, gastrointestinal symptoms, and self-reported dietary intake after gastric bypass versus sleeve gastrectomy: a randomized
study
Anna Laurenius, Ola Wallengren, Aiham Alaraj, Helene Berteus Forslund, A. Thorell, Ville Wallenius, Almantas Maleckas
Surgery for Obesity and Related Diseases - 2023 -
Effects of medical and surgical treatment on vitamin D levels in
obesity
Ala Mejaddam, Gudrun Höskuldsdóttir, Frida Lenér, Ville Wallenius, Penelope Trimpou, Lars Fändriks, Lars Fändriks, Björn Eliasson, Kerstin Landin-Wilhelmsen
PLoS ONE - 2023 -
The value of "diaphragmatic relaxing incision" for the durability of the crural repair in patients with paraesophageal hernia: a double blind randomized clinical
trial
Alexandros Tsoposidis, A. Thorell, Hans Axelsson, M. Reuterwall Hansson, L. Lundell, Ville Wallenius, Srdjan Kostic, B. Hakanson
FRONTIERS IN SURGERY - 2023 -
Comparing effects of obesity treatment with very low energy diet and bariatric surgery after 2 years: a prospective cohort
study
Gudrun Höskuldsdóttir, My Engström, Araz Rawshani, Frida Lenér, Ville Wallenius, Lars Fändriks, Karin Mossberg, Björn Eliasson
Bmj Open - 2022 -
Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant
cultures
Matus Sotak, Meenu Rohin Rajan, Madison Clark, M. Harms, Alankrita Rani, Jamie D. Kraft, David Tandio, T. Shen, K. Borkowski, O. Fiehn, J. W. Newman, Marianne Quiding-Järbrink, Christina Biörserud, Peter Apelgren, Trude Staalesen, C. E. Hagberg, Jeremie Boucher, Ville Wallenius, Stefan Lange, Emma Börgeson
iScience - 2022 -
The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity
development.
Elodie Picarda, Phillip M Galbo, Haihong Zong, Meenu Rohin Rajan, Ville Wallenius, Deyou Zheng, Emma Börgeson, Rajat Singh, Jeffrey Pessin, Xingxing Zang
Science advances - 2022 -
Morphological Adaptation in the Jejunal Mucosa after Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers: Data from a Randomized Crossover
Study
Anna Casselbrant, Ville Wallenius, Erik Elebring, Hanns-Ulrich Marschall, Bengt R Johansson, Herbert F Helander, Lars Fändriks
Nutrients - 2022 -
A Fatty Diet Induces a Jejunal Ketogenesis Which Inhibits Local SGLT1-Based Glucose Transport via an Acetylation Mechanism-Results from a Randomized Cross-Over Study between Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy
Volunteers
Erik Elebring, Ville Wallenius, Anna Casselbrant, N. G. Docherty, C. W. le Roux, Hanns-Ulrich Marschall, Lars Fändriks
Nutrients - 2022 -
Healthy Subcutaneous and Omental Adipose Tissue Is Associated with High Expression of Extracellular Matrix
Components
Matus Sotak, Meenu Rohin Rajan, Madison Clark, Christina Biörserud, Ville Wallenius, C. E. Hagberg, Emma Börgeson
International Journal of Molecular Sciences - 2022 -
Glycemic Control and Metabolic Adaptation in Response to High-Fat versus High-Carbohydrate Diets-Data from a Randomized Cross-Over Study in Healthy
Subjects.
Ville Wallenius, Erik Elebring, Anna Casselbrant, Anna Laurenius, Carel W le Roux, Neil G Docherty, Christina Biörserud, Niclas Björnfot, My Engström, Hanns-Ulrich Marschall, Lars Fändriks
Nutrients - 2021 -
Laparoscopic Heller myotomy or pneumatic dilatation in achalasia: results of a prospective, randomized study with at least a decade of
follow-up
Ehsan Sediqi, Alexandros Tsoposidis, Ville Wallenius, Hans Axelsson, Jan Persson, Erik Johnsson, L. Lundell, Srdjan Kostic
Surgical Endoscopy - 2021 -
The BAriatic surgery SUbstitution and nutrition (BASUN) population: a data-driven exploration of predictors for
obesity
Gudrun Höskuldsdóttir, My Engström, Araz Rawshani, Ville Wallenius, Frida Lenér, Lars Fändriks, Karin Mossberg, Björn Eliasson
Bmc Endocrine Disorders - 2021 -
Intestinal sodium/glucose cotransporter 3 expression is epithelial and downregulated in
obesity.
Matus Sotak, Anna Casselbrant, Tamara Zietek, Maria Strömstedt, Damilola D Adingupu, Daniel Karlsson, Maria Fritsch Fredin, Peter Ergang, Jiří Pácha, Anna Batorsky, Charles E Alpers, Emma Börgeson, Pernille Hansen, Anette Ericsson, Anna Björnson Granqvist, Ville Wallenius, Lars Fändriks, Robert J Unwin
Life sciences - 2021 -
Impact of obesity on intensive care outcomes in patients with COVID-19 in Sweden—A cohort
study
Lovisa Sjögren, Erik Stenberg, Meena Thuccani, Jari Martikainen, Christian Rylander, Ville Wallenius, Torsten Olbers, Jenny Kindblom
PLoS ONE - 2021 -
Significant over- and misuse of
PPIs
L. Agreus, L. Borgquist, Alexandros Tsoposidis, Ville Wallenius, S. Kostic, L. Lundell, G. Lindberg
Lakartidningen - 2021 -
Sleeve gastrectomy and Roux-en-Y gastric bypass in the treatment of type 2 diabetes. Two-year results from a Swedish multicenter randomized controlled
trial
Ville Wallenius, Aiham Alaraj, Niclas Björnfot, Bengt Orrenius, Anders Kylebäck, Per Björklund, Malin Werling, A. Thorell, Lars Fändriks, Almantas Maleckas
Surgery for Obesity and Related Diseases - 2020 -
Potential Benefits and Harms of Gastric Bypass Surgery in Obese Individuals With Type 1 Diabetes: A Nationwide, Matched, Observational Cohort
Study.
Gudrun Höskuldsdóttir, Jan Ekelund, Mervete Miftaraj, Ville Wallenius, Johan Ottosson, Ingmar Näslund, Soffia Gudbjörnsdottir, Naveed Sattar, Ann-Marie Svensson, Björn Eliasson
Diabetes care - 2020 -
Suppression of enteroendocrine cell glucagon-like peptide (GLP)-1 release by fat-induced small intestinal ketogenesis: a mechanism targeted by Roux-en-Y gastric bypass surgery but not by preoperative very-low-calorie
diet.
Ville Wallenius, Erik Elias, Erik Elebring, Bauke Haisma, Anna Casselbrant, Pierre Larraufie, Emma Spak, Frank Reimann, Carel W le Roux, Neil G Docherty, Fiona M Gribble, Lars Fändriks
Gut - 2020 -
Fucose-Galactose Polymers Inhibit Cholera Toxin Binding to Fucosylated Structures and Galactose-Dependent Intoxication of Human
Enteroids.
Jakob Cervin, Andrew Boucher, Gyusaang Youn, Per Björklund, Ville Wallenius, Lynda Mottram, Nicole S Sampson, Ulf Yrlid
ACS infectious diseases - 2020 -
Glycocholic acid and butyrate synergistically increase vitamin D-induced calcium uptake in Caco-2 intestinal epithelial cell
monolayers
Anna Casselbrant, Lars Fändriks, Ville Wallenius
Bone Reports - 2020 -
Design and baseline data in the BAriatic surgery SUbstitution and Nutrition study (BASUN): a 10-year prospective cohort
study
Gudrun Höskuldsdóttir, Karin Mossberg, Ville Wallenius, Angelos Al Nimer, Wiveka Björkvall, Sören Lundberg, C. J. Behre, Malin Werling, Björn Eliasson, Lars Fändriks
BMC Endocrine Disorders - 2020 -
Rates and types of injuries during the three consecutive years 2016 to 2018 of the Vätternrundan - One of the world's largest and longest bicycle
races
Karin Sillén, Ville Wallenius
Traffic Injury Prevention - 2019 -
Proteomic Approach to the Potential Role of Angiotensin II in Barrett
Dysplasia
Svein-Olav Bratlie, Ville Wallenius, Anders Edebo, Lars Fändriks, Anna Casselbrant
Proteomics - Clinical Applications - 2019 -
The gut microbiota is a major regulator of androgen metabolism in intestinal
contents.
Hannah Colldén, Andreas Landin, Ville Wallenius, Erik Elebring, Lars Fändriks, Maria E. Nilsson, Henrik Ryberg, Matti Poutanen, Klara Sjögren, Liesbeth Vandenput, Claes Ohlsson
American journal of physiology. Endocrinology and metabolism - 2019 -
Comparative analysis of obesity-related cardiometabolic and renal biomarkers in human plasma and
serum.
Meenu Rohin Rajan, Matus Sotak, Fredrik Barrenäs, Tong Shen, Kamil Borkowski, Nicholas J. Ashton, Christina Biörserud, Tomas L Lindahl, Sofia Ramström, Michael Schöll, Per Lindahl, Oliver Fiehn, John W Newman, Rosie Perkins, Ville Wallenius, Stephan Lange, Emma Börgeson
Scientific reports - 2019 -
GM1 ganglioside-independent intoxication by Cholera
toxin
Jakob Cervin, Amberlyn M Wands, Anna Casselbrant, Han Wu, Soumya Krishnamurthy, Aleksander Cvjetkovic, Johanna Estelius, Benjamin Dedic, Anirudh Sethi, Kerri-Lee Wallom, Rebecca E Riise, Malin Bäckström, Ville Wallenius, Frances M Platt, Michael Lebens, Susann Teneberg, Lars Fändriks, Jennifer J Kohler, Ulf Yrlid
PLoS Pathogens - 2018 -
Biliopancreatic Diversion is associated with greater increases in energy expenditure than Roux-en-Y Gastric
Bypass
Malin Werling, Lars Fändriks, Torsten Olbers, T. Mala, J. Kristinsson, K. Stenlof, Ville Wallenius, Neil G. Docherty, Carel W le Roux
Plos One - 2018 -
Glycemic Control after Sleeve Gastrectomy and Roux-En-Y Gastric Bypass in Obese Subjects with Type 2 Diabetes
Mellitus
Ville Wallenius, E. Dirinck, Lars Fändriks, Almantas Maleckas, Carel W le Roux, A. Thorell
Obesity Surgery - 2018 -
Obesity-induced changes in lipid mediators persist after weight
loss
A. Hernandez-Carretero, N. Weber, M. R. La Frano, W. Ying, Juan Lantero Rodriguez, D. D. Sears, Ville Wallenius, Emma Börgeson, J. W. Newman, O. Osborn
International Journal of Obesity - 2018 -
Fucosylated Molecules Competitively Interfere with Cholera Toxin Binding to Host
Cells.
Amberlyn M Wands, Jakob Cervin, He Huang, Ye Zhang, Gyusaang Youn, Chad A Brautigam, Maria Matson Dzebo, Per Björklund, Ville Wallenius, Danielle K Bright, Clay S Bennett, Pernilla Wittung-Stafshede, Nicole S Sampson, Ulf Yrlid, Jennifer J Kohler
ACS infectious diseases - 2018 -
AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of
adiponectin.
Emma Börgeson, Ville Wallenius, Gulam H Syed, Manjula Darshi, Juan Lantero Rodriguez, Christina Biörserud, Malin Ragnmark Ek, Per Björklund, Marianne Quiding-Järbrink, Lars Fändriks, Catherine Godson, Kumar Sharma
Diabetologia - 2017 -
Efficacy and safety of bariatric surgery for craniopharyngioma-related hypothalamic obesity: a matched case-control study with 2 years of
follow-up.
M Wijnen, Daniel S Olsson, M M van den Heuvel-Eibrink, Ville Wallenius, J A M J L Janssen, P J D Delhanty, A J van der Lely, Gudmundur Johannsson, S J C M M Neggers
International journal of obesity (2005) - 2017 -
Bariatric surgery for diabetes mellitus type 2 control in adults with BMI<35
kg/m2
Lars Fändriks, E-L Daxberg, Björn Eliasson, Lennart Jivegård, Madelene Sandqvist, Ville Wallenius, Petteri Sjögren
2016 -
Expression of tight-junction proteins in human proximal small intestinal mucosa before and after Roux-en-Y gastric bypass
surgery
Anna Casselbrant, Erik Elias, Lars Fändriks, Ville Wallenius
Surgery for Obesity and Related Diseases - 2015 -
Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal
mucosa
Mantas Malinauskas, Ville Wallenius, Lars Fändriks, Anna Casselbrant
Journal of the renin-angiotensin-aldosterone system - 2015 -
Angiotensin II exerts dual actions on sodium-glucose transporter 1-mediated transport in the human jejunal
mucosa
Anna Casselbrant, Mantas Malinauskas, Hanns-Ulrich Marschall, Ville Wallenius, Lars Fändriks
Scandinavian Journal of Gastroenterology - 2015 -
Roux-en-Y Gastric Bypass Surgery Increases Respiratory Quotient and Energy Expenditure during Food
Intake
Malin Werling, Lars Fändriks, Torsten Olbers, Marco Bueter, Lars Sjöström, Hans Lönroth, Ville Wallenius, Kaj Stenlöf, Carel W le Roux
PLoS ONE - 2015 -
Surgery in the treatment of type 2 diabetes
mellitus.
Almantas Maleckas, L Venclauskas, Ville Wallenius, Hans Lönroth, Lars Fändriks
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society - 2015 -
Bone mineral density and expression of vitamin D receptor-dependent calcium uptake mechanisms in the proximal small intestine after bariatric
surgery
Erik Elias, Anna Casselbrant, Malin Werling, K Abegg, RP Vincent, J Alaghband-Zadeh, Torsten Olbers, Carel W le Roux, Lars Fändriks, Ville Wallenius
British Journal of Surgery - 2014 -
Correction: Gastric Bypass Surgery Is Followed by Lowered Blood Pressure and Increased Diuresis - Long Term Results from the Swedish Obese Subjects (SOS)
Study.
Peter Hallersund, Lars Sjöström, Torsten Olbers, Hans Lönroth, Peter Jacobson, Ville Wallenius, Ingmar Näslund, Lena M S Carlsson, Lars Fändriks
PloS one - 2013 -
Interleukin-6 mediates exercise-induced increase in insulin sensitivity in
mice.
Anna Benrick, Ville Wallenius, Ingrid Wernstedt Asterholm
Experimental physiology - 2012 -
Gastric Bypass Surgery Is Followed by Lowered Blood Pressure and Increased Diuresis - Long Term Results from the Swedish Obese Subjects (SOS)
Study.
Peter Hallersund, Lars Sjöström, Torsten Olbers, Hans Lönroth, Peter Jacobson, Ville Wallenius, Ingmar Näslund, Lena M S Carlsson, Lars Fändriks
PloS one - 2012 -
The lipocalins retinol-binding protein-4, lipocalin-2 and lipocalin-type prostaglandin D2-synthase correlate with markers of inflammatory activity, alcohol intake and blood lipids, but not with insulin sensitivity in metabolically healthy 58-year-old Swedish
men
Ville Wallenius, Erik Elias, Göran Bergström, Henrik Zetterberg, Carl Johan Behre
Experimental and clinical endocrinology & diabetes - 2011 -
Central nervous system lipocalin-type prostaglandin D2-synthase is correlated with orexigenic neuropeptides, visceral adiposity and markers of the hypothalamic-pituitary-adrenal axis in obese
humans.
Erik Elias, Anna Benrick, Carl Johan Behre, Rolf Ekman, Henrik Zetterberg, Kaj Stenlöf, Ville Wallenius
Journal of neuroendocrinology - 2011 -
Erythrocyte sodium-lithium countertransport activity is inversely correlated to adiponectin, retinol binding protein 4 and body
height.
Erik Elias, Ville Wallenius, Hans Herlitz, Göran Bergström, Fredrik J. Olson, Carl Johan Behre
Scandinavian journal of clinical and laboratory investigation - 2010 -
Point-counterpoint: Interleukin-6 does/does not have a beneficial role in insulin sensitivity and glucose
homeostasis.
John-Olov Jansson, Ville Wallenius
Journal of applied physiology (Bethesda, Md. : 1985) - 2007 -
Interleukin-1 system gene polymorphisms are associated with fat mass in young
men.
Louise Strandberg, Mattias Lorentzon, Åsa Hellqvist, Staffan Nilsson, Ville Wallenius, Claes Ohlsson, John-Olov Jansson
The Journal of clinical endocrinology and metabolism - 2006 -
Reduced stress- and cold-induced increase in energy expenditure in interleukin-6-deficient
mice.
Ingrid Wernstedt, Amanda Edgley, Anna Berndtsson, Jenny Fäldt, Göran Bergström, Ville Wallenius, John-Olov Jansson
American journal of physiology. Regulatory, integrative and comparative physiology - 2006 -
Mature-onset obesity in interleukin-1 receptor I knockout
mice.
Maria C García, Ingrid Wernstedt, Anna Berndtsson, Maria Enge, Michal Bell, Olof H. Hultgren, Michael Horn, Bo Ahrén, Sven Enerbäck, Claes Ohlsson, Ville Wallenius, John-Olov Jansson
Diabetes - 2006 -
Increased levels of acylation-stimulating protein in interleukin-6-deficient (IL-6(-/-))
mice
Ingrid Wernstedt, Bob Olsson, Margareta Jernås, S. Paglialunga, Lena M S Carlsson, Ulf Smith, K. Cianflone, Kristina Wallenius, Ville Wallenius
Endocrinology - 2006 -
Lack of complement factor C3, but not factor B, increases hyperlipidemia and atherosclerosis in apolipoprotein E-/- low-density lipoprotein receptor-/-
mice
Linda Persson, Jan Borén, A. K. Robertson, Ville Wallenius, G. K. Hansson, Marcela Pekna
Arterioscler Thromb Vasc Biol - 2004 -
Interleukin-6 levels in the central nervous system are negatively correlated with fat mass in overweight/obese
subjects.
Kaj Stenlöf, Ingrid Wernstedt, Ted Fjällman, Ville Wallenius, Kristina Wallenius, John-Olov Jansson
The Journal of clinical endocrinology and metabolism - 2003 -
On the site and mechanism of action of the anti-obesity effects of
interleukin-6.
John-Olov Jansson, Kristina Wallenius, Ingrid Wernstedt, Claes Ohlsson, Suzanne L. Dickson, Ville Wallenius
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society - 2003 -
Interleukin-6-deficient mice develop mature-onset
obesity.
Ville Wallenius, Kristina Wallenius, Bo Ahrén, Mats Rudling, Hans Carlsten, Suzanne L. Dickson, Claes Ohlsson, John-Olov Jansson
Nature medicine - 2002 -
Retarded liver growth in interleukin-6-deficient and tumor necrosis factor receptor-1-deficient
mice.
Ville Wallenius, Kristina Wallenius, Masanori Hisaoka, Jonas Sandstedt, Claes Ohlsson, M Kopf, John-Olov Jansson
Endocrinology - 2001 -
Independent amplification of two gene clusters on chromosome 4 in rat endometrial cancer: identification and molecular
characterization.
A Walentinsson, Khalil Helou, Ville Wallenius, H J Hedrich, C Szpirer, G Levan
Cancer research - 2001 -
Liver-derived IGF-I regulates GH secretion at the pituitary level in
mice.
Kristina Wallenius, Klara Sjögren, X D Peng, S Park, Ville Wallenius, J L Liu, M. Umaerus, H Wennbo, Olle Isaksson, L Frohman, R Kineman, Claes Ohlsson, John-Olov Jansson
Endocrinology - 2001 -
Hormonal regulation of liver and tumor
growth
Ville Wallenius
2000 -
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in
mice.
Klara Sjögren, J L Liu, K Blad, Stanko Skrtic, Olle Vidal, Ville Wallenius, D LeRoith, Jan Törnell, Olle Isaksson, John-Olov Jansson, Claes Ohlsson
Proceedings of the National Academy of Sciences of the United States of America - 1999