- Home
- About
- Find staff
- Karolina Skibicka
Karolina Skibicka
Professor
Department of PhysiologyAbout Karolina Skibicka
PhD in Neuroscience, University of Pennsylvania BSc in Biology and Psychology, University of South Florida
Research group
-
Lateral parabrachial nucleus astrocytes control food
intake
Devesh Mishra, Jennifer E. Richard, Ivana Maric, Olesya Shevchouk, Stina Börchers, Kim Eerola, Jean-Philippe Krieger, Karolina P Skibicka
FRONTIERS IN ENDOCRINOLOGY - 2024 -
Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse
model
Manisha Samad, C. Joakim Ek, Stina Börchers, Jean-Philippe Krieger, Elisabet Stener-Victorin, Karolina P Skibicka, Ingrid Wernstedt Asterholm, Anna Benrick
SCIENTIFIC REPORTS - 2024 -
Sex-divergent effects of hindbrain GLP-1-producing neuron activation in
rats
Lorena López-Ferreras, Mohammed Asker, Jean-Philippe Krieger, Karolina P Skibicka
Frontiers in Neuroscience - 2023 -
From the stomach to locus coeruleus: new neural substrate for ghrelin’s effects on ingestive, motivated and anxiety-like
behaviors
Ivana Maric, Lorena López-Ferreras, Yashaswini Bhat, Mohammed Asker, Stina Börchers, Lauren Bellfy, Suyeun Byun, Janine L. Kwapis, Karolina P Skibicka
Frontiers in Pharmacology - 2023 -
An appetite for aggressive behavior? Female rats, too, derive reward from winning aggressive
interactions
Stina Börchers, Jil Carl, Katharina Schormair, Jean-Philippe Krieger, Mohammed Asker, Christian Edvardsson, Elisabeth Jerlhag, Karolina P Skibicka
Translational Psychiatry - 2023 -
Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance
effects
Mohammed Asker, Jean-Philippe Krieger, A. Liles, I. C. Tinsley, T. Borner, Ivana Maric, S. Doebley, C. D. Furst, Stina Börchers, Francesco Longo, Y. R. Bhat, B. C. De Jonghe, M. R. Hayes, R. P. Doyle, Karolina P Skibicka
Diabetes Obesity & Metabolism - 2023 -
Commonly-used rodent tests of anxiety-like behavior lack predictive validity for human sex
differences.
Stina Börchers, Jean-Philippe Krieger, Mohammed Asker, Ivana Maric, Karolina P Skibicka
Psychoneuroendocrinology - 2022 -
A Cre-driver rat model for anatomical and functional analysis of glucagon (Gcg)-expressing cells in the brain and
periphery
H. Zheng, Lorena López-Ferreras, Jean-Philippe Krieger, S. Fasul, V. Cea Salazar, N. Valderrama Pena, Karolina P Skibicka, L. Rinaman
Molecular Metabolism - 2022 -
From an Empty Stomach to Anxiolysis: Molecular and Behavioral Assessment of Sex Differences in the Ghrelin Axis of
Rats
Stina Börchers, Jean-Philippe Krieger, Ivana Maric, Jil Carl, Maral Abraham, Francesco Longo, Mohammed Asker, Jennifer E. Richard, Karolina P Skibicka
Frontiers in Endocrinology - 2022 -
Sex and Species Differences in the Development of Diet-Induced Obesity and Metabolic Disturbances in
Rodents.
Ivana Maric, Jean-Philippe Krieger, Pauline van der Velden, Stina Börchers, Mohammed Asker, Milica Vujičić, Ingrid Wernstedt Asterholm, Karolina P Skibicka
Frontiers in nutrition - 2022 -
Hindbrain insulin controls feeding
behavior
Kim Eerola, Francesco Longo, Thomas Reinbothe, Jennifer E. Richard, Olesya Shevchouk, Lorena Lopez-Ferreras, Devesh Mishra, Mohammed Asker, Johan Tolö, Caroline Miranda, Musovic Saliha, Charlotta S Olofsson, Patrik Rorsman, Karolina P Skibicka
Molecular Metabolism - 2022 -
Neural Pathway for Gut Feelings: Vagal Interoceptive Feedback From the Gastrointestinal Tract Is a Critical Modulator of Anxiety-like
Behavior
Jean-Philippe Krieger, Mohammed Asker, Pauline van der Velden, Stina Börchers, Jennifer E. Richard, Ivana Maric, Francesco Longo, A. Singh, G. de Lartigue, Karolina P Skibicka
Biological Psychiatry - 2022 -
Key role for hypothalamic interleukin-6 in food-motivated behavior and body weight
regulation
Lorena López-Ferreras, Francesco Longo, Jennifer E. Richard, Kim Eerola, Olesya Shevchouk, Madeleine Tuzinovic, Karolina P Skibicka
Psychoneuroendocrinology - 2021 -
Ghrelin Receptor Stimulation of the Lateral Parabrachial Nucleus in Rats Increases Food Intake but not Food
Motivation
Tina Bake, Marie Le May, Christian Edvardsson, Heike Vogel, Ulrika Bergström, Marjorie Nicholson Albers, Karolina P Skibicka, I. Farkas, Z. Liposits, Suzanne L. Dickson
Obesity - 2020 -
The supramammillary nucleus controls anxiety-like behavior; key role of
GLP-1R
Lorena Lopez-Ferreras, Kim Eerola, Olesya Shevchouk, Jennifer E. Richard, Fredrik H. Nilsson, L. E. Jansson, M. R. Hayes, Karolina P Skibicka
Psychoneuroendocrinology - 2020 -
Ultrafast Glutamate Biosensor Recordings in Brain Slices Reveal Complex Single Exocytosis
Transients
Yuanmo Wang, Devesh Mishra, Jenny Bergman, J. D. Keighron, Karolina P Skibicka, A. S. Cans
Acs Chemical Neuroscience - 2019 -
Interleukin-6 in the central amygdala is bioactive and co-localised with glucagon-like peptide-1
receptor
Fredrik Anesten, Adria Dalmau Gasull, Jennifer E. Richard, Imre Farkas, Devesh Mishra, Lilly Taing, F. Zhang, Matti Poutanen, Vilborg Palsdottir, Z. Liposits, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2019 -
Glucagon-Like Peptide-1-, but not Growth and Differentiation Factor 15-, Receptor Activation Increases the Number of Interleukin-6-Expressing Cells in the External Lateral Parabrachial
Nucleus
Fredrik Anesten, Devesh Mishra, Adria Dalmau Gasull, Linda Engström-Ruud, Jakob Bellman, Vilborg Palsdottir, F Zhang, S. Trapp, Karolina P Skibicka, Matti Poutanen, John-Olov Jansson
Neuroendocrinology - 2019 -
Parabrachial Interleukin-6 Reduces Body Weight and Food Intake and Increases Thermogenesis to Regulate Energy
Metabolism
Devesh Mishra, Jennifer E. Richard, Ivana Maric, B. Porteiro, M. Haring, S. Kooijman, Musovic Saliha, Kim Eerola, Lorena Lopez-Ferreras, Eduard Peris, Katarzyna Grycel, Olesya Shevchouk, Peter Micallef, Charlotta S Olofsson, Ingrid Wernstedt Asterholm, H. J. Grill, R. Nogueiras, Karolina P Skibicka
Cell Reports - 2019 -
GLP-1 modulates the supramammillary nucleus-lateral hypothalamic neurocircuit to control ingestive and motivated behavior in a sex divergent
manner
Lorena López-Ferreras, Kim Eerola, Devesh Mishra, Olesya Shevchouk, Jennifer E. Richard, Fredrik H. Nilsson, M. R. Hayes, Karolina P Skibicka
Molecular Metabolism - 2019 -
Counting the Number of Glutamate Molecules in Single Synaptic
Vesicles
Y. M. Wang, H. Fathali, Devesh Mishra, T. Olsson, J. D. Keighron, Karolina P Skibicka, A. S. Cans
Journal of the American Chemical Society - 2019 -
Lateral hypothalamic GLP-1 receptors are critical for the control of food reinforcement, ingestive behavior and body
weight
Lorena López-Ferreras, Jennifer E. Richard, E. E. Noble, Kim Eerola, Rozita H Anderberg, Kajsa Olandersson, Lilly Taing, S. E. Kanoski, M. R. Hayes, Karolina P Skibicka
Molecular Psychiatry - 2018 -
Functional interleukin-6 receptor- is located in tanycytes at the base of the third
ventricle
Fredrik Anesten, Cristiano Santos, Edwin Gidestrand, Erik Schéle, Vilborg Palsdottir, Teodor Swedung-Wettervik, B. Meister, Karolina P Skibicka, John-Olov Jansson
Journal of Neuroendocrinology - 2017 -
Glucagon-Like Peptide 1 and Its Analogs Act in the Dorsal Raphe and Modulate Central Serotonin to Reduce Appetite and Body
Weight
Rozita H Anderberg, Jennifer E. Richard, Kim Eerola, Lorena López-Ferreras, Elin Banke, Caroline Hansson, Hans Nissbrandt, Filip Bergquist, F. M. Gribble, F. Reimann, Ingrid Wernstedt Asterholm, C. M. Lamy, Karolina P Skibicka
Diabetes - 2017 -
Estradiol is a critical regulator of food-reward
behavior
Jennifer E. Richard, Lorena López-Ferreras, Rozita H Anderberg, Kajsa Olandersson, Karolina P Skibicka
Psychoneuroendocrinology - 2017 -
Ghrelin's control of food reward and body weight in the lateral hypothalamic area is sexually
dimorphic
Lorena López-Ferreras, Jennifer E. Richard, Rozita H Anderberg, Fredrik H. Nilsson, Kajsa Olandersson, S. E. Kanoski, Karolina P Skibicka
Physiology & Behavior - 2017 -
Vagal Blocking for Obesity Control: a Possible
Mechanism-Of-Action
H. Johannessen, David Revesz, Y. Kodama, N. Cassie, Karolina P Skibicka, P. Barrett, Suzanne L. Dickson, J. Holst, J. Rehfeld, G. van der Plasse, R. Adan, B. Kulseng, Elinor Ben-Menachem, C. M. Zhao, D. Chen
Obesity Surgery - 2017 -
CNS beta(3)-adrenergic receptor activation regulates feeding behavior, white fat browning, and body
weight
Jennifer E. Richard, Lorena López-Ferreras, Belén Chanclón, Kim Eerola, Peter Micallef, Karolina P Skibicka, Ingrid Wernstedt Asterholm
American Journal of Physiology-Endocrinology and Metabolism - 2017 -
Preproglucagon neurons in the hindbrain have IL-6 receptor-α and show Ca2+ influx in response to
IL-6
Fredrik Anesten, M. K. Holt, Erik Schéle, Vilborg Palsdottir, F. Reimann, F. M. Gribble, Cecilia Safari, Karolina P Skibicka, S. Trapp, John-Olov Jansson
American Journal of Physiology. Regulatory Integrative and Comparative Physiology - 2016 -
GLP-1 and estrogen conjugate acts in the supramammillary nucleus to reduce food-reward and body
weight
Heike Vogel, Stefanie Wolf, Cristina Rabasa-Papio, Francisca Rodriguez-Pacheco, Carina S. Babaei, F. Stöber, J. Goldschmidt, R. D. DiMarchi, B. Finan, M. H. Tschöp, Suzanne L. Dickson, A. Schürmann, Karolina P Skibicka
Neuropharmacology - 2016 -
The Stomach-Derived Hormone Ghrelin Increases Impulsive
Behavior.
Rozita H Anderberg, Caroline Hansson, Maya Fenander, Jennifer E. Richard, Suzanne L. Dickson, Hans Nissbrandt, Filip Bergquist, Karolina P Skibicka
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 2016 -
GLP-1 is both anxiogenic and antidepressant; divergent effects of acute and chronic GLP-1 on
emotionality.
Rozita H Anderberg, Jennifer E. Richard, Caroline Hansson, Hans Nissbrandt, Filip Bergquist, Karolina P Skibicka
Psychoneuroendocrinology - 2016 -
Sex and estrogens alter the action of glucagon-like peptide-1 on
reward
Jennifer E. Richard, Rozita H Anderberg, Lorena López-Ferreras, Kajsa Olandersson, Karolina P Skibicka
Biology of Sex Differences - 2016 -
Food Hedonics: Insight from Animal
Models
Karolina P Skibicka, S. E. Kanoski
Neuroendocrinology of Appetite. Suzanne L. Dickson, Julian G. Mercer (eds.) - 2016 -
GLP-1 and weight loss: unraveling the diverse neural
circuitry
S. E. Kanoski, M. R. Hayes, Karolina P Skibicka
American Journal of Physiology-Regulatory Integrative and Comparative Physiology - 2016 -
Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the
offspring.
Min Hu, Jennifer E. Richard, Manuel Maliqueo, Milana Kokosar, Romina Fornes, Anna Benrick, Thomas Jansson, Claes Ohlsson, Xiaoke Wu, Karolina P Skibicka, Elisabet Stener-Victorin
Proceedings of the National Academy of Sciences of the United States of America - 2015 -
Activation of the GLP-1 Receptors in the Nucleus of the Solitary Tract Reduces Food Reward Behavior and Targets the Mesolimbic
System
Jennifer E. Richard, Rozita H Anderberg, Andreas Göteson, F. M. Gribble, F. Reimann, Karolina P Skibicka
Plos One - 2015 -
GLP-1 Receptor Stimulation of the Lateral Parabrachial Nucleus Reduces Food Intake: Neuroanatomical, Electrophysiological, and Behavioral
Evidence
Jennifer E. Richard, I. Farkas, Fredrik Anesten, Rozita H Anderberg, Suzanne L. Dickson, F. M. Gribble, F. Reimann, John-Olov Jansson, Z. Liposits, Karolina P Skibicka
Endocrinology - 2014 -
Dopamine signaling in the amygdala, increased by food ingestion and GLP-1, regulates feeding
behavior.
Rozita H Anderberg, Christine Anefors, Filip Bergquist, Hans Nissbrandt, Karolina P Skibicka
Physiology & behavior - 2014 -
Influence of ghrelin on the central serotonergic signaling system in
mice
Caroline Hansson, Mayte Alvarez-Crespo, Magdalena Taube, Karolina P Skibicka, Linnéa Schmidt, Linda Karlsson-Lindahl, Emil Egecioglu, Hans Nissbrandt, Suzanne L. Dickson
Neuropharmacology - 2014 -
The central GLP-1: Implications for food and drug
reward
Karolina P Skibicka
Frontiers in Neuroscience - 2013 -
Hypothalamic κ-Opioid Receptor Modulates the Orexigenic Effect of
Ghrelin.
Amparo Romero-Picó, Maria J Vázquez, David González-Touceda, Cintia Folgueira, Karolina P Skibicka, Mayte Alvarez-Crespo, Margriet A Van Gestel, Douglas A Velásquez, Christoph Schwarzer, Herbert Herzog, Miguel López, Roger A. H. Adan, Suzanne L. Dickson, Carlos Diéguez, Rubén Nogueiras
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 2013 -
Divergent circuitry underlying food reward and intake effects of ghrelin: Dopaminergic VTA-accumbens projection mediates ghrelin's effect on food reward but not food
intake.
Karolina P Skibicka, Rozita H. Shirazi, Cristina Rabasa-Papio, Mayte Alvarez-Crespo, Corinna Neuber, Heike Vogel, Suzanne L. Dickson
Neuropharmacology - 2013 -
Ghrelin, reward and
motivation.
John R W Menzies, Karolina P Skibicka, Gareth Leng, Suzanne L. Dickson
Endocrine development - 2013 -
Enteroendocrine hormones-central effects on
behavior
Suzanne L. Dickson, Karolina P Skibicka
Current opinion in pharmacology - 2013 -
Glucagon-like peptide 1 receptor induced suppression of food intake, and body weight is mediated by central IL-1 and
IL-6
Rozita H. Shirazi, Vilborg Palsdottir, Jim Collander, Fredrik Anesten, Heike Vogel, F. Langlet, A. Jaschke, A. Schurmann, V. Prevot, Linus Ruijin Shao, John-Olov Jansson, Karolina P Skibicka
Proceedings of the National Academy of Sciences of the United States of America - 2013 -
Gut Peptide GLP-1 and Its Analogue, Exendin-4, Decrease Alcohol Intake and
Reward
Rozita H. Shirazi, Suzanne L. Dickson, Karolina P Skibicka
Plos One - 2013 -
Role of ghrelin in the pathophysiology of eating disorders: Implications for
pharmacotherapy
Sebastian Cardona Cano, Myrte Merkestein, Karolina P Skibicka, Suzanne L. Dickson, Roger A.H. Adan
CNS Drugs - 2012 -
Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene
expression.
Karolina P Skibicka, Caroline Hansson, Emil Egecioglu, Suzanne L. Dickson
Addiction biology - 2012 -
Ghrelin Influences Novelty Seeking Behavior in Rodents and
Men
Caroline Hansson, Rozita H. Shirazi, Jakob Näslund, Heike Vogel, Corinna Neuber, Göran Holm, Henrik Anckarsäter, Suzanne L. Dickson, Elias Eriksson, Karolina P Skibicka
Plos One - 2012 -
The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: a new role for mesolimbic GLP-1
receptors.
Suzanne L. Dickson, Rozita H. Shirazi, Caroline Hansson, Filip Bergquist, Hans Nissbrandt, Karolina P Skibicka
The Journal of neuroscience : the official journal of the Society for Neuroscience - 2012 -
Ghrelin interacts with neuropeptide Y Y1 and opioid receptors to increase food
reward.
Karolina P Skibicka, Rozita H. Shirazi, Caroline Hansson, Suzanne L. Dickson
Endocrinology - 2012 -
Neural Substrates Underlying Interactions between Appetite Stress and
Reward.
John R W Menzies, Karolina P Skibicka, Suzanne L. Dickson, Gareth Leng
Obesity facts - 2012 -
The Amygdala as a Neurobiological Target for Ghrelin in Rats: Neuroanatomical, Electrophysiological and Behavioral
Evidence
Mayte Alvarez-Crespo, Karolina P Skibicka, I. Farkas, C. S. Molnar, Emil Egecioglu, E. Hrabovszky, Z. Liposits, Suzanne L. Dickson
Plos One - 2012 -
The role of the central ghrelin system in reward from food and chemical
drugs.
Suzanne L. Dickson, Emil Egecioglu, Sara Landgren, Karolina P Skibicka, Jörgen Engel, Elisabeth Jerlhag
Molecular and cellular endocrinology - 2011 -
Hedonic and incentive signals for body weight
control.
Emil Egecioglu, Karolina P Skibicka, Caroline Hansson, Mayte Alvarez-Crespo, P. Anders Friberg, Elisabeth Jerlhag, Jörgen Engel, Suzanne L. Dickson
Reviews in endocrine & metabolic disorders - 2011 -
Ghrelin directly targets the ventral tegmental area to increase food
motivation.
Karolina P Skibicka, Caroline Hansson, Mayte Alvarez-Crespo, P. Anders Friberg, Suzanne L. Dickson
Neuroscience - 2011 -
Ghrelin and food reward: The story of potential underlying
substrates.
Karolina P Skibicka, Suzanne L. Dickson
Peptides - 2011 -
Ghrelin increases intake of rewarding food in
rodents.
Emil Egecioglu, Elisabeth Jerlhag, Nicolas Salomé, Karolina P Skibicka, David Haage, Mohammad Bohlooly-Yeganeh, Daniel Andersson, Mikael Bjursell, Daniel Perrissoud, Jörgen Engel, Suzanne L. Dickson
Addiction biology - 2010 -
Blockade of central nicotine acetylcholine receptor signaling attenuate ghrelin-induced food intake in
rodents.
Suzanne L. Dickson, E Hrabovszky, Caroline Hansson, Elisabeth Jerlhag, Mayte Alvarez-Crespo, Karolina P Skibicka, C S Molnar, Z Liposits, Jörgen Engel, Emil Egecioglu
Neuroscience - 2010