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Anna Djos
Associate Researcher
Department of Laboratory Medicine-
Long-Lasting Response to Lorlatinib in Patients with ALK-Driven Relapsed or Refractory Neuroblastoma Monitored with Circulating Tumor DNA
Analysis
Torben Ek, Raghda Ragab Mohamed Hassan Ahmed Ibrahim, Hartmut Vogt, Kleopatra Georgantzi, Catarina Trager, Jennie Gaarder, Anna Djos, Ida Rahmqvist, Elisabeth Mellström, Fani Pujol-Calderón, Christoffer Vannas, Lina Hansson, Henrik Fagman, Diana Treis, Susanne Fransson, Tobias Österlund, Tzu-Po Chuang, Bronte Manouk Verhoeven, Anders Ståhlberg, Ruth H. Palmer, Bengt Hallberg, Tommy Martinsson, Per Kogner, Martin Dalin
Cancer Research Communications - 2024 -
Heterogeneous SSTR2 target expression and a novel KIAA1549::BRAF fusion clone in a progressive metastatic lesion following 177Lutetium-DOTATATE molecular radiotherapy in neuroblastoma: a case
report
Se Whee Sammy Park, Susanne Fransson, Fredrik Sundquist, Joachim N. Nilsson, Per Gryback, Sandra Wessman, Jacob Stromgren, Anna Djos, Henrik Fagman, Helene Sjoegren, Kleopatra Georgantzi, Nikolas Herold, Per Kogner, Dan Granberg, Mark N. Gaze, Tommy Martinsson, Kasper Karlsson, Jakob J. E. Stenman
FRONTIERS IN ONCOLOGY - 2024 -
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in
neuroblastoma
Ketan Thombare, Roshan Vaid, Perla Pucci, Kristina Ihrmark Lundberg, Ritish Ayyalusamy, Mohammad Hassan Baig, Akram Mendez, Rebeca Burgos-Panadero, Stefanie Hoeppner, Christoph Bartenhagen, Daniel Sjövall, Aqsa Ali Rehan, Sagar Dattatraya Nale, Anna Djos, Tommy Martinsson, Pekka Jaako, Jae-June Dong, Per Kogner, John Inge Johnsen, Matthias Fischer, Suzanne D. Turner, Tanmoy Mondal
EMBO JOURNAL - 2024 -
Altered methylation of imprinted genes in neuroblastoma: implications for prognostic
refinement
Medha Suman, Maja Löfgren, Susanne Fransson, Jewahri Idris Yousuf, Johanna Svensson, Anna Djos, Tommy Martinsson, Per Kogner, Teresia Kling, Helena Carén
JOURNAL OF TRANSLATIONAL MEDICINE - 2024 -
Loss of Chromosome Y in Neuroblastoma Is Associated With High-Risk Disease, 11q-Deletion, and Telomere
Maintenance
Anna Djos, Johanna Svensson, Jennie Gaarder, Ganesh Umapathy, Staffan Nilsson, Torben Ek, Hartmut Vogt, Kleopatra Georgantzi, Ingrid Ora, Catarina Trager, Per Kogner, Tommy Martinsson, Susanne Fransson
GENES CHROMOSOMES & CANCER - 2024 -
METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive
neuroblastoma
Roshan Vaid, Ketan Thombare, Akram Mendez, Rebeca Burgos-Panadero, Anna Djos, Daniel Jachimowicz, Kristina Ihrmark Lundberg, Christoph Bartenhagen, Navinder Kumar, Conny Tummler, Carina Sihlbom, Susanne Fransson, John Inge Johnsen, Per Kogner, Tommy Martinsson, Matthias Fischer, Tanmoy Mondal
NUCLEIC ACIDS RESEARCH - 2024 -
Telomere Maintenance Mechanisms in a Cohort of High-Risk Neuroblastoma Tumors and Its Relation to Genomic Variants in the TERT and ATRX
Genes
Anna Djos, Ketan Thombare, Roshan Vaid, Jennie Gaarder, Ganesh Umapathy, Susanne E Reinsbach, Kleopatra Georgantzi, Jakob Stenman, Helena Carén, Torben Ek, Tanmoy Mondal, Per Kogner, Tommy Martinsson, Susanne Fransson
CANCERS - 2023 -
Identification of recurrent 3q13.31 chromosomal rearrangement indicates LSAMP as a tumor suppressor gene in
neuroblastoma
Angela Martinez-Monleon, Jostein Gaarder, Anna Djos, P. Kogner, Susanne Fransson
International Journal of Oncology - 2023 -
Novel human-derived EML4-ALK fusion cell lines identify ribonucleotide reductase RRM2 as a target of activated ALK in
NSCLC
Abdulmalik Bokhari, Wei-Yun Lai, A. T. Le, Jonatan L. Gabre, Tzu-Po Chuang, Susanne Fransson, B. Bergman, Anna Djos, N. Chen, Tommy Martinsson, J. Van den Eynden, R. C. Doebele, Ruth H. Palmer, Bengt Hallberg, Ganesh Umapathy
Lung Cancer - 2022 -
Whole exome sequencing identifies KIF26B, LIFR and LAMC1 mutations in familial vesicoureteral
reflux
Zsuzsa Bartik, Ulla Sillén, Anna Djos, A. Lindholm, Susanne Fransson
Plos One - 2022 -
Multifocal Neuroblastoma and Central Hypoventilation in An Infant with Germline ALK F1174I
Mutation
Anna Djos, D. Treis, Susanne Fransson, L. G. Murkes, S. Wessman, J. Asmundsson, A. Markstrom, P. Kogner, Tommy Martinsson
Diagnostics - 2022 -
Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma
subgroup
Angela Martinez-Monleon, Hanna Kryh Öberg, Jostein Gaarder, A. P. Berbegall, Niloufar Javanmardi, Anna Djos, M. Ussowicz, S. Taschner-Mandl, I. M. Ambros, I. Ora, B. Sandstedt, K. Beiske, R. Ladenstein, R. Noguera, P. F. Ambros, L. G. Murkes, G. Ljungman, P. Kogner, Susanne Fransson, Tommy Martinsson
Scientific Reports - 2022 -
Sustained Response to Entrectinib in an Infant With a Germline ALKAL2 Variant and Refractory Metastatic Neuroblastoma With Chromosomal 2p Gain and Anaplastic Lymphoma Kinase and Tropomyosin Receptor Kinase
Activation
D. Treis, Ganesh Umapathy, Susanne Fransson, Jikui Guan, Patricia Mendoza-García, Joachim T. Siaw, S. Wessman, L. G. Murkes, J. J. E. Stenman, Anna Djos, L. H. M. Elfman, J. I. Johnsen, Bengt Hallberg, Ruth H. Palmer, Tommy Martinsson, P. Kogner
JCO Precision Oncology - 2022 -
A genome-wide scan to locate regions associated with familial vesicoureteral
reflux
Zsuzsa Bartik, Ulla Sillén, Malin Östensson, Susanne Fransson, Anna Djos, Rose-Marie Sjöberg, Tommy Martinsson
Experimental and Therapeutic Medicine - 2022 -
11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in
Neuroblastoma
Joachim T. Siaw, Niloufar Javanmardi, Jimmy Van den Eynden, Dan E. Lind, Susanne Fransson, Angela Martinez-Monleon, Anna Djos, Rose-Marie Sjöberg, Malin Östensson, H. Caren, G. Troen, K. Beiske, A. P. Berbegall, R. Noguera, Wei-Yun Lai, P. Kogner, Ruth H. Palmer, Bengt Hallberg, Tommy Martinsson
Cell Reports - 2020 -
Analysis of ALK, MYCN, and the ALK ligand ALKAL2 (FAM150B/AUG alpha) in neuroblastoma patient samples with chromosome arm 2p
rearrangements
Niloufar Javanmardi, Susanne Fransson, Anna Djos, Ganesh Umapathy, Malin Östensson, J. Milosevic, Marcus Borenäs, Bengt Hallberg, P. Kogner, Tommy Martinsson, Ruth H. Palmer
Genes Chromosomes & Cancer - 2020 -
Low Frequency ALK Hotspots Mutations In Neuroblastoma Tumours Detected By Ultra-deep Sequencing: Implications For ALK Inhibitor
Treatment
Niloufar Javanmardi, Susanne Fransson, Anna Djos, Rose-Marie Sjöberg, Staffan Nilsson, Katarina Truvé, P. Kogner, Tommy Martinsson
Scientific Reports - 2019 -
MEK inhibitor trametinib does not prevent the growth of anaplastic lymphoma kinase (ALK)-addicted
neuroblastomas.
Ganesh Umapathy, Jikui Guan, Dan Gustafsson, Niloufar Javanmardi, Diana Lizeth Cervantes-Madrid, Anna Djos, Tommy Martinsson, Ruth H. Palmer, Bengt Hallberg
Science signaling - 2017 -
Comparative genetic study of intratumoral heterogenous MYCN amplified neuroblastoma versus aggressive genetic profile neuroblastic
tumors
A. P. Berbegall, E. Villamon, M. Piqueras, I. Tadeo, Anna Djos, P. F. Ambros, Tommy Martinsson, I. M. Ambros, A. Canete, V. Castel, S. Navarro, R. Noguera
Oncogene - 2016 -
Estimation of copy number aberrations: Comparison of exome sequencing data with SNP microarrays identifies homozygous deletions of 19q13.2 and iin
neuroblastoma
Susanne Fransson, Malin Östensson, Anna Djos, Niloufar Javanmardi, P. Kogner, Tommy Martinsson
International Journal of Oncology - 2016 -
Intragenic anaplastic lymphoma kinase (ALK) rearrangements: Translocations as a novel mechanism of ALK activation in neuroblastoma
tumors.
Susanne Fransson, Magnus Hansson, Kristina Ruuth, Anna Djos, Ana Berbegall, Niloufar Javanmardi, Jonas Abrahamsson, Ruth H. Palmer, Rosa Noguera, Bengt Hallberg, Per Kogner, Tommy Martinsson
Genes, chromosomes & cancer - 2015 -
Emergence of New ALK Mutations at Relapse of
Neuroblastoma
G. Schleiermacher, Niloufar Javanmardi, V. Bernard, Q. Leroy, J. Cappo, T. R. Frio, G. Pierron, E. Lapouble, V. Combaret, F. Speleman, B. de Wilde, Anna Djos, I. Ora, F. Hedborg, C. Trager, B. M. Holmqvist, Jonas Abrahamsson, M. Peuchmaur, J. Michon, I. Janoueix-Lerosey, P. Kogner, O. Delattre, Tommy Martinsson
Journal of Clinical Oncology - 2014 -
Aneuploidy in neuroblastoma tumors is not associated with inactivating point mutations in the STAG2
gene.
Anna Djos, Susanne Fransson, Per Kogner, Tommy Martinsson
BMC medical genetics - 2013 -
Genetic Instability and Intratumoral Heterogeneity in Neuroblastoma with MYCN Amplification Plus 11q
Deletion
E. Villamon, A. P. Berbegall, M. Piqueras, I. Tadeo, V. Castel, Anna Djos, Tommy Martinsson, S. Navarro, R. Noguera
PLoS ONE - 2013 -
Anaplastic Lymphoma Kinase (ALK) regulates initiation of transcription of MYCN in neuroblastoma
cells
C. Schönherr, K. Ruuth, S. Kamaraj, C. L. Wang, H. L. Yang, V. Combaret, Anna Djos, Tommy Martinsson, J. G. Christensen, R. H. Palmer, B. Hallberg
Oncogene - 2012 -
The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in
neuroblastoma.
Anna Djos, Tommy Martinsson, Per Kogner, Helena Carén
Molecular cancer - 2012 -
Identification of epigenetically regulated genes that predict patient outcome in
neuroblastoma
Helena Carén, Anna Djos, Maria Nethander, Rose-Marie Sjöberg, Per Kogner, Camilla Enström, Staffan Nilsson, Tommy Martinsson
BMC Cancer - 2011